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ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:46 PM EDT

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Showing 193–216 of 751 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mental Health (Depression) Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Digital Tools for Coping With Chronic Pain

NCT03234439
View directory record Official record
Conditions
Chronic Pain, Depression, Anxiety, Opioid Use
Interventions
myStrength
Behavioral
Lead sponsor
MyStrength, Inc.
Other
Eligibility
18 Years to 85 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
12
States / cities
Los Angeles, California • San Francisco, California • Denver, Colorado + 9 more
Source: ClinicalTrials.gov public record
Updated Jan 4, 2019 · Synced Oct 19, 2026, 1:46 PM EDT
Not yet recruiting Not applicable Interventional

Reduction of Depression Through Dual Treatment: Digital CBT & NBHWC Coaching

NCT07195292
View directory record Official record
Conditions
Hearing Disability, Depression, Mobility Disability
Interventions
Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
Device
Lead sponsor
Toivoa Inc
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The DC Mother-Infant Behavioral Wellness Program

NCT05345834
View directory record Official record
Conditions
Perinatal Depression, Perinatal Anxiety, Prenatal Stress
Interventions
Patient Navigation, Adapted Cognitive-Behavioral Therapy
Behavioral
Lead sponsor
Children's National Research Institute
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
700 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 24, 2025 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

FASTLANE II: Reducing Sex, Drug, and Mental Health Risk

NCT04109014
View directory record Official record
Conditions
Methamphetamine Abuse, HIV/AIDS, Depression, Sex, Unsafe
Interventions
FASTLANE II
Other
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

Pharmacogenetic Testing in an Outpatient Population of Patients With Depression

NCT02497027
View directory record Official record
Conditions
Depression
Interventions
pharmacogenetic testing
Other
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
18 Years and older
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated May 3, 2017 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

iWellness Study to Evaluate a Mental Health App for Students

NCT05234970
View directory record Official record
Conditions
Depression, Anxiety
Interventions
Wysa, Harvard College App
Other
Lead sponsor
Harvard University
Other
Eligibility
18 Years and older
Enrollment
289 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 7, 2023 · Synced Oct 19, 2026, 1:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia

NCT06493825
View directory record Official record
Conditions
Tinnitus, Misophonia
Interventions
Aurora Mindfulness app versus sham
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
10 Years to 18 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 19, 2026, 1:46 PM EDT
Not yet recruiting Not applicable Interventional

Task-Shifting Adapted IPT-A for Youth Suicide Prevention

NCT07383831
View directory record Official record
Conditions
Suicidal Ideation, Depressive Symptoms, Adolescent Mental Health
Interventions
Adapted Brief Interpersonal Psychotherapy for Adolescents (IPT-A LAZOS), Usual Community Center Services
Behavioral · Other
Lead sponsor
Boston College
Other
Eligibility
12 Years to 17 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Chestnut Hill, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional Results available

EnBrace HR for Depression Treatment and Prevention in Women Trying to Conceive and Early Pregnancy

NCT02676882
View directory record Official record
Conditions
Depressive Disorder, Pregnancy
Interventions
EnBrace HR
Dietary Supplement
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 20, 2019 · Synced Oct 19, 2026, 1:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health and Health Care Utilization Effects of Medical Debt Forgiveness

NCT04835012
View directory record Official record
Conditions
Health Care Utilization, Depression, Anxiety, Subjective Wellbeing
Interventions
Medical debt forgiveness
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
15,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Radicle Health1: A Study of Health and Wellness Formulations and Their Effects on Overall Health

NCT05783232
View directory record Official record
Conditions
Sleep, Pain, Depression, Anxiety
Interventions
Placebo Control Form 1 Capsules, Health Active Study Product 1.1 Capsules, Health Active Study Product 1.2 Capsules, Health Active Study Product 1.3 Capsules
Dietary Supplement
Lead sponsor
Radicle Science
Industry
Eligibility
21 Years to 105 Years
Enrollment
1,494 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Del Mar, California
Source: ClinicalTrials.gov public record
Updated Nov 22, 2023 · Synced Oct 19, 2026, 1:46 PM EDT
Active, not recruiting Not applicable Interventional

The Development of an Integrated Physical Activity and Mental Health Intervention for Veterans With COPD, Emotion Distress, and Low Physical Activity

NCT04953806
View directory record Official record
Conditions
COPD, Depression, Anxiety
Interventions
Step-CBT
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Not listed Not applicable Interventional

Testing Mediators and Moderators of a Fotonovela for Depression to Promote Help-seeking Behavior

NCT04319458
View directory record Official record
Conditions
Mental Health Literacy
Interventions
Fotonovela, Control
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
182 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2020 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

Mood and Nutrition Interventions in Polycystic Ovary Syndrome

NCT01899001
View directory record Official record
Conditions
Polycystic Ovary Syndrome (PCOS)
Interventions
Cognitive Behavioral Therapy, Nutrition Counseling
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2016 · Synced Oct 19, 2026, 1:46 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Digital Single Session Intervention for Youth Mental Health

NCT05449002
View directory record Official record
Conditions
Anxiety, Depression, Conduct Disorder, Stress
Interventions
Practicing the Opposite (PTO), Usual Clinical Care
Behavioral · Other
Lead sponsor
Harvard University
Other
Eligibility
9 Years to 17 Years
Enrollment
226 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
5
States / cities
Indianapolis, Indiana • Boston, Massachusetts • Concord, Massachusetts + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

SMS Messaging to Reduce Depression and Anxiety Following TBI

NCT02061553
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Motivation, Intention, BA-Tech
Behavioral
Lead sponsor
Albert Einstein Healthcare Network
Other
Eligibility
18 Years and older
Enrollment
119 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2023
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 23, 2023 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study on Prevalence, Protection and Recovery From COVID-19 in Seasoned Yoga Practitioners in Comparison to Age and Gender Matched Controls

NCT04498442
View directory record Official record
Conditions
Covid19, Stress, Anxiety Depression
Interventions
Simha Kriya, Reading a Book
Behavioral
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
8,519 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2022 · Synced Oct 19, 2026, 1:46 PM EDT
Withdrawn Phase 4 Interventional

EnBrace HR for PMS With Prominent Mood Symptoms or Menstrual Related Mood Disorders

NCT04123483
View directory record Official record
Conditions
Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Premenstrual Tension, Menstrual Related Mood Disorder
Interventions
EnBrace HR Softgel
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 52 Years · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 2, 2020 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

REstoring Mental Health Through COmmUnity-based Psychological Services in New York City

NCT04913766
View directory record Official record
Conditions
Depression, Anxiety, Psychological Distress, PTSD
Interventions
Problem Management Plus, Services as Usual
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years and older
Enrollment
1,206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Phase 1 Interventional

E-health Intervention for Cancer Survivors

NCT01114802
View directory record Official record
Conditions
Cancer
Interventions
Project Onward website + social network, Project Onward website
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
19 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 19, 2014 · Synced Oct 19, 2026, 1:46 PM EDT
Withdrawn Not applicable Interventional

Evaluating the Feasibility of Disseminating a Novel Mobile Platform to Treat Depression

NCT02817672
View directory record Official record
Conditions
Depression
Interventions
PRIME 1.0, PRIME 2.0
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 22, 2020 · Synced Oct 19, 2026, 1:46 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Enhancing Health in Rural Populations: Music as Therapy

NCT07538427
View directory record Official record
Conditions
Stress, Generalized Anxiety, Chronic Pain, Depression Disorder
Interventions
Music Based Intervention
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
Not listed
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Flagstaff, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 20, 2026 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional

Mental Health Disparities in Spanish Speaking Latina Breast Cancer Patients

NCT04834154
View directory record Official record
Conditions
Breast Cancer, Depression, Anxiety, Mindfulness, Sleep Disturbance
Interventions
Mindfulness, Control group
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Oct 19, 2026, 1:46 PM EDT
Completed Not applicable Interventional Results available

Reaching and Engaging Depressed Senior Center Clients (REDS)

NCT03246789
View directory record Official record
Conditions
Depression, Unipolar, Mental Health Disorder
Interventions
Engage-M, Wellness in Mind and Body
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
55 Years to 100 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 19, 2022 · Synced Oct 19, 2026, 1:46 PM EDT