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ClinicalTrials.gov public records Last synced Sep 30, 2026, 12:57 AM EDT

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Showing 25–48 of 789 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mental Wellbeing Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Trauma and Cardiometabolic Health in an American Indian Community

NCT06878885
View directory record Official record
Conditions
Psychological Stress, Cardiometabolic Conditions, Mental Health
Interventions
Acute psychological stress task (Paced Auditory Serial Addition Task)
Behavioral
Lead sponsor
Montana State University
Other
Eligibility
18 Years to 40 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Browning, Montana
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 30, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Testing the Effectiveness and Implementation of a Meditation App for Youth in the Legal System

NCT06997120
View directory record Official record
Conditions
Behavioral Health
Interventions
Bodhi AIM (intervention group), HIB (control group)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
13 Years to 20 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Enhancing Well-Being Through Exercise During Old Age

NCT04536727
View directory record Official record
Conditions
Depression, Osteoarthritis
Interventions
Fit & Strong!, Wait list
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
60 Years and older
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Project Uplift: Substance Use and Mental Health Treatment for Young Sexual and Gender Minorities

NCT04546061
View directory record Official record
Conditions
Substance Use, Mental Health
Interventions
Project Uplift
Behavioral
Lead sponsor
Duke University
Other
Eligibility
18 Years to 35 Years
Enrollment
112 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Charlotte, North Carolina • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Sep 30, 2026, 12:57 AM EDT
Completed No phase listed Observational

Optimizing Medication Management for Mothers With Depression

NCT02519790
View directory record Official record
Conditions
Depression, Pregnancy
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Galveston, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Nov 17, 2021 · Synced Sep 30, 2026, 12:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation

NCT05082246
View directory record Official record
Conditions
Anxiety, Depression, Stress, Pain, Heart Rate, Blood Pressure
Interventions
Conscious Breathing, Heartfulness Meditation, Emotional Freedom Technique
Other
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional

Yoga Online Feasibility to Reduce PTSD

NCT02925481
View directory record Official record
Conditions
PTSD
Interventions
Moderate Online yoga participation, Stretching and toning, Low dose online yoga participation
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 30, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Health and Health Care Utilization Effects of Medical Debt Forgiveness

NCT04835012
View directory record Official record
Conditions
Health Care Utilization, Depression, Anxiety, Subjective Wellbeing
Interventions
Medical debt forgiveness
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
15,008 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing a Wellness App for First Responders, Military Personnel and Veterans

NCT06336967
View directory record Official record
Conditions
Mental Health Wellness
Interventions
GUIDE
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Sep 30, 2026, 12:57 AM EDT
Not yet recruiting Phase 1 Interventional Accepts healthy volunteers

Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia

NCT06644573
View directory record Official record
Conditions
Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder, REM Sleep Measurement, Insomnia, Insomnia Related to Specified Disorder, Insomnia Due to Other Mental Disorder, Insomnia Comorbid to Psychiatric Disorder, Insomnia Due to Anxiety and Fear, Insomnia Related to Another Mental Condition, Insomnia Disorders, Idiopathic Hypersomnia, Sleep Disorders, Circadian Rhythm, Post Trauma Nightmares, PTSD - Post Traumatic Stress Disorder, Sleep Quality, Anesthesia, Anxiety, Depression, Mental Health, Alzheimer Disease or Associated Disorder, Parkinsons, Circadian Rhythm, Circadian Dysregulation, PTSD, Post-Traumatic, Post-Traumatic Stress Disorder Complex, Military Combat Stress Reaction, Sleep, Military Activity, Veterans, Shift Work Sleep Disorder, Menopause Related Conditions, Pain, Cancer Pain, Athletes
Interventions
PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca, Continuous EEG Monitoring
Procedure · Drug · Device
Lead sponsor
Nyree Penn
Industry
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Aventura, Florida
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acceptance and Commitment Therapy Delivered by Automated Software Messaging

NCT04329897
View directory record Official record
Conditions
Hip Osteoarthritis, Knee Osteoarthritis, Mental Stress, Coronavirus
Interventions
Software Messaging
Behavioral
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 16, 2020 · Synced Sep 30, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cold and Heat Investigation to Lower Levels of Depression

NCT06263738
View directory record Official record
Conditions
Depression, Mood Disorders, Healthy (Controls)
Interventions
Whole Body Hyperthermia, Cold Water Plunge
Procedure
Lead sponsor
Barry Sandler
Other
Eligibility
18 Years to 65 Years
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Edwards, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Phase 4 Interventional Results available

Phase IV:Safety and Efficacy of EMSAM in Adolescents With Major Depression

NCT00531947
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Selegiline Transdermal System, Placebo
Drug
Lead sponsor
Somerset Pharmaceuticals
Industry
Eligibility
12 Years to 17 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
20
States / cities
Dothan, Alabama • National City, California • San Diego, California + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 15, 2014 · Synced Sep 30, 2026, 12:57 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

CREST: Samphire Guided Care Program on Wellbeing, Work Productivity, and Quality of Life

NCT07679074
View directory record Official record
Conditions
Premenstrual Syndrome, Premenstrual Dysphoric Disorder, Dysmenorrhea, Endometriosis, Perimenopause, Menopause, Pelvic Pain
Interventions
Lutea Transcranial Direct Current Stimulation (tDCS) Device, Samphire Guided Care Program
Device · Behavioral
Lead sponsor
Samphire Group, Inc.
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Results available

An Integrated Care Model for Improving Hepatitis C Virus Patient Outcomes

NCT00722423
View directory record Official record
Conditions
Hepatitis C
Interventions
Integrated care model, Usual Care Model
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 75 Years
Enrollment
364 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
3
States / cities
Palo Alto, California • San Diego, California • The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 15, 2015 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Use of Mentoring to Promote Well-being for Female SMART Members

NCT04247880
View directory record Official record
Conditions
Harassment, Non-Sexual, Harassment, Sexual, Bullying, Workplace, Mental Stress, Work-Related Condition, Work-related Injury, Work Related Stress
Interventions
Mentoring program
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
19
States / cities
Phoenix, Arizona • Glendora, California • San Jose, California + 16 more
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Results available

EM/PROTECT: Improving Depression in Elder Mistreatment Victims

NCT03241225
View directory record Official record
Conditions
Depression
Interventions
EM/PROTECT, EM/MH
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
55 Years to 100 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 3, 2022 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Strengths-based Linkage to Alcohol Care (SLAC) for Hazardous Drinkers in Primary Care

NCT05023317
View directory record Official record
Conditions
Alcohol-induced Disorders, Alcohol Drinking, Mental Health
Interventions
Strengths-based linkage to alcohol care, Usual care
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
140 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
2
States / cities
Little Rock, Arkansas • Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Sanctuary Youth Series Randomized Control Trial

NCT06693713
View directory record Official record
Conditions
Mental Health, Mental Health Help-Seeking, Mental Health Literacy
Interventions
Mental Health Youth Series
Other
Lead sponsor
Sanctuary Mental Health Ministries
Other
Eligibility
11 Years to 18 Years
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Sep 30, 2026, 12:57 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Optimizing a Drug Abuse Prevention Program for Dissemination

NCT03125291
View directory record Official record
Conditions
Substance Abuse, Mental Health, Educational Problems
Interventions
Bridges 4-week Program
Behavioral
Lead sponsor
Arizona State University
Other
Eligibility
10 Years to 15 Years
Enrollment
664 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Tempe, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 5, 2018 · Synced Sep 30, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Perspective on Thoughts and Feelings as a Predictor of Psychological Well-being in Daily Life, in a Community Sample

NCT03336710
View directory record Official record
Conditions
Mental Health, Mindfulness
Interventions
Not listed
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 65 Years
Enrollment
380 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 30, 2019 · Synced Sep 30, 2026, 12:57 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Prevention and Early Identification for High Risk Youth in School-based Clinics

NCT04935710
View directory record Official record
Conditions
Community Mental Health Services, Adolescent Well Being, Resilience, Psychological, Health Equity, Screening
Interventions
COPE2Thrive, Usual care
Behavioral · Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
12 Years to 24 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
5
States / cities
Cambridge, Massachusetts • Everett, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 18, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Storytelling and Mindfulness for Graduate Student Wellbeing

NCT05826860
View directory record Official record
Conditions
Depression, Anxiety, Burnout, Student
Interventions
Mindfulness Practice, Storytelling Workshop
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Sep 30, 2026, 12:57 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Anxiety Level Assessment of Anesthesia Providers During COVID-19 Pandemic

NCT05212909
View directory record Official record
Conditions
Anxiety
Interventions
General Anxiety Disorder-7 scale
Behavioral
Lead sponsor
Augusta University
Other
Eligibility
Not listed
Enrollment
105 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 23, 2022 · Synced Sep 30, 2026, 12:57 AM EDT