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ClinicalTrials.gov public records Last synced Oct 18, 2026, 8:52 AM EDT

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Showing 1345–1368 of 18,720 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolic Disease Clear all
Completed Phase 2 Interventional Results available

A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes

NCT02097277
View directory record Official record
Conditions
Diabetes Mellitus Type 2
Interventions
BMS-986036, Placebo (Matching with BMS-986036)
Biological
Lead sponsor
Bristol-Myers Squibb
Industry
Eligibility
Not listed
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
10
States / cities
Little Rock, Arkansas • Anaheim, California • Los Angeles, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Oct 18, 2026, 8:52 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Exercise Training as an Intervention to Improve Muscle Function and Recovery Following Bed Rest in Older Adults With Type 2 Diabetes

NCT04057677
View directory record Official record
Conditions
Type 2 Diabetes, Muscular Atrophy, Sedentary Behavior, Exercise, Pre-diabetes
Interventions
Bed Rest Intervention, Exercise Program
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
60 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jun 6, 2025 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Nitisinone (NTBC) In Different Age Groups Of Patients With Alkaptonuria

NCT01390077
View directory record Official record
Conditions
Alkaptonuria
Interventions
Nitisinone
Drug
Lead sponsor
University of California, San Diego
Other
Eligibility
Not listed
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Phase 2 Interventional Results available

Vericiguat in Patients With Metabolic Syndrome and Coronary Vascular Dysfunction

NCT05711719
View directory record Official record
Conditions
Metabolic Syndrome, Coronary Microvascular Dysfunction
Interventions
Vericiguat, Placebo
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
35 Years to 85 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALS

NCT05003167
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Expiratory Muscle Strength Training (EMST-150)
Device
Lead sponsor
Purdue University
Other
Eligibility
40 Years to 70 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Oct 18, 2026, 8:52 AM EDT
Recruiting Phase 3 Interventional

Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients

NCT03127267
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis
Interventions
Masitinib (6.0), Riluzole, Placebo, Masitinib (4.5)
Drug
Lead sponsor
AB Science
Industry
Eligibility
18 Years to 81 Years
Enrollment
495 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
6
States / cities
Birmingham, Alabama • Los Angeles, California • Lexington, Kentucky + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 12, 2025 · Synced Oct 18, 2026, 8:52 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Do Single Use Negative Pressure Dressings Reduce Wound Complications in Obese Women After Cesarean Delivery

NCT02799667
View directory record Official record
Conditions
Obesity, Surgical Site Infections, Wound Complications, Complications; Cesarean Section
Interventions
Standard Dressing, Negative Pressure Wound Therapy Dressing
Device
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Phase 4 Interventional

Nutrition Intervention in AIDS Wasting

NCT00006167
View directory record Official record
Conditions
HIV Wasting Syndrome
Interventions
oxandrolone, Progressive Resistance Training
Drug · Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2000
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Phase 3 Interventional Results available

Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia

NCT00626392
View directory record Official record
Conditions
Dyslipidemia
Interventions
niacin extended-release (NER), aspirin (ASA), aspirin placebo (ASA Pbo)
Drug
Lead sponsor
Abbott
Industry
Eligibility
18 Years and older
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
26
States / cities
Huntsville, Alabama • Scottsdale, Arizona • Tucson, Arizona + 22 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2009 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Study on Impact of Lifestyle Change and Weight Loss Before Bariatric Surgery

NCT00623792
View directory record Official record
Conditions
Severe Obesity, Bariatric Surgery
Interventions
Preoperative lifestyle Intervention
Behavioral
Lead sponsor
Duquesne University
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2016 · Synced Oct 18, 2026, 8:52 AM EDT
Recruiting No phase listed Observational

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

NCT07567131
View directory record Official record
Conditions
Erythropoietic Protoporphyria (EPP), X-Linked Porphyria (XLP)
Interventions
Not listed
Lead sponsor
Portal Therapeutics, Inc.
Industry
Eligibility
12 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Wake Forest, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional Results available

Support and Tracking to Achieve Results (Project STAR)

NCT04116853
View directory record Official record
Conditions
Obesity
Interventions
ADAPTIVE Extended-Care Program, STATIC Extended-Care Program
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 70 Years
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Guided Imagery Intervention for Obese Latino Adolescents

NCT01895595
View directory record Official record
Conditions
Obesity, Insulin Resistance, Metabolic Syndrome
Interventions
Guided Imagery, Digital Storytelling
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
14 Years to 17 Years
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers

Red Yeast Rice and Phytosterols In Statin Intolerance

NCT00897975
View directory record Official record
Conditions
Hyperlipidemia
Interventions
red yeast rice, phytosterol, therapeutic lifestyle program, placebo
Dietary Supplement · Drug · Behavioral
Lead sponsor
Chestnut Hill Health System
Other
Eligibility
21 Years and older
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
2
States / cities
Abington, Pennsylvania • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 18, 2011 · Synced Oct 18, 2026, 8:52 AM EDT
Recruiting Phase 2 Interventional

TIRzepatide for the Treatment of Obesity in Patients With Atrial Fibrillation

NCT06802081
View directory record Official record
Conditions
Atrial Fibrillation, Obesity
Interventions
Tirzepatide, Placebo
Drug
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 13, 2026 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention for Adults With Diabetes

NCT02699307
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Counseling
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
65 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Oct 18, 2026, 8:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

PregSource: Crowdsourcing to Understand Pregnancy

NCT02577536
View directory record Official record
Conditions
Pregnancy, Pregnancy Complications, Morning Sickness, Diabetes, Gestational, Placenta Diseases, Birth Weight
Interventions
No Interventions
Other
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
18 Years to 70 Years · Female only
Enrollment
2,359 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 7, 2024 · Synced Oct 18, 2026, 8:52 AM EDT
Terminated Phase 4 Interventional

Sustainability of Vitamin D Levels After Repletion With Ergocalciferol In Chronic Kidney Disease Stage 5D

NCT01312441
View directory record Official record
Conditions
Vitamin D Deficiency, Renal Failure Chronic Requiring Hemodialysis
Interventions
Ergocalciferol, Placebo
Drug
Lead sponsor
Albany College of Pharmacy and Health Sciences
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
4
States / cities
Albany, New York • Clifton Park, New York • Saratoga Springs, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2016 · Synced Oct 18, 2026, 8:52 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Implementation of a Cardiometabolic Disease Staging System in Primary Care

NCT04922294
View directory record Official record
Conditions
Diabetes, Obesity, Overweight
Interventions
Clinical decision support system
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
20 Years to 90 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 20, 2022 · Synced Oct 18, 2026, 8:52 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Glycemic Metrics and Patterns in People With and Without Prediabetes

NCT06921902
View directory record Official record
Conditions
Pre Diabetes
Interventions
FreeStyle Libre 3
Device
Lead sponsor
Abbott Diabetes Care
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bend, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Insulet Artificial Pancreas Early Feasibility Study

NCT02897557
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Insulet Artificial Pancreas (AP) System
Device
Lead sponsor
Insulet Corporation
Industry
Eligibility
6 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
4
States / cities
Palo Alto, California • Santa Barbara, California • Walnut Creek, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 9, 2021 · Synced Oct 18, 2026, 8:52 AM EDT
Completed Not applicable Interventional

Cleveland Clinic Families Get Fit (CCFit) : A Family-based Activity-Monitor Intervention in Pediatric Obesity

NCT04312919
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Family Based Activity Intervention
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
8 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Oct 18, 2026, 8:52 AM EDT
Terminated Phase 2 Interventional Results available

Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)

NCT05217667
View directory record Official record
Conditions
Homozygous Familial Hypercholesterolemia
Interventions
ARO-ANG 3 Injection
Drug
Lead sponsor
Arrowhead Pharmaceuticals
Industry
Eligibility
16 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
Mount Sinai, New York • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2026 · Synced Oct 18, 2026, 8:52 AM EDT
Terminated Phase 3 Interventional

Efficacy of Lapaquistat Acetate Co-Administered With Statins in Subjects With Hypercholesterolemia

NCT00532311
View directory record Official record
Conditions
Hypercholesterolemia
Interventions
Lapaquistat acetate and stable statin therapy, Stable statin therapy
Drug
Lead sponsor
Takeda
Industry
Eligibility
18 Years and older
Enrollment
411 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
86
States / cities
Birmingham, Alabama • Huntsville, Alabama • Mobile, Alabama + 83 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2016 · Synced Oct 18, 2026, 8:52 AM EDT