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Showing 1–24 of 3,414 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Metabolic Effects Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Fitness Drink Formulas on Energy Expenditure and Fat Metabolism

NCT04455009
View directory record Official record
Conditions
Caffeine, Diet, Healthy, Fat Burn, Cognitive Change, Fatigue
Interventions
Fitness Drink Formula
Dietary Supplement
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 35 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 1, 2020 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preliminary Effect of Food Processing and Sweeteners on Glycemic and Metabolic Measures

NCT05658757
View directory record Official record
Conditions
Blood Sugar; High, Blood Pressure, Dietary Habits
Interventions
Regular sweetened commercial foods, Allulose sweetened commercial foods, Whole and minimally processed and sweetened foods
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
20 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated May 2, 2023 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effect of LAPS-Exendin on Body Weight in Obese Population

NCT02075281
View directory record Official record
Conditions
Obesity
Interventions
HM11260C, Placebo
Biological
Lead sponsor
Hanmi Pharmaceutical Company Limited
Industry
Eligibility
18 Years to 64 Years
Enrollment
297 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 8, 2016 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 3 Interventional Results available

A Research Study to Compare Two Types of Insulin, a New Weekly Insulin, Insulin Icodec and an Available Daily Insulin, Insulin Degludec, in People With Type 2 Diabetes Who Use Daily Insulin

NCT04770532
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
Insulin degludec, Insulin Icodec
Drug
Lead sponsor
Novo Nordisk A/S
Industry
Eligibility
Not listed
Enrollment
526 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
38
States / cities
Buena Park, California • Encino, California • Fresno, California + 32 more
Source: ClinicalTrials.gov public record
Updated Dec 14, 2025 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 3 Interventional

Anit-Inflammatory and Anti-Oxidative Nutrition in Dialysis Patients

NCT00561093
View directory record Official record
Conditions
Hypoalbuminemia, Protein-energy Malnutrition, Inflammation, Oxidative Stress, Chronic Kidney Disease (CKD) Hemodialysis
Interventions
pentoxiphylline, Nepro, anti-inflammatory module (similar to Oxepa), Placebo pill imitating pentoxiphylline, Placebo to imitate Nepro, Placebo to imitate anti-inflammatory module (similar to Oxepa)
Drug · Dietary Supplement
Lead sponsor
Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
93 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
2
States / cities
Irvine, California • Torrance, California
Source: ClinicalTrials.gov public record
Updated May 20, 2015 · Synced Jul 23, 2026, 1:29 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Snacks and Satiety

NCT03947281
View directory record Official record
Conditions
Eating Behavior, Overweight, Obesity
Interventions
Almond snack, Cereal-based snack
Other
Lead sponsor
USDA, Western Human Nutrition Research Center
Federal
Eligibility
18 Years to 45 Years · Female only
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2024 · Synced Jul 23, 2026, 1:29 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Chronic Sleep Restriction in Young and Older People

NCT00506428
View directory record Official record
Conditions
Aging, Sleep Deprivation, Metabolic Syndrome
Interventions
chronic sleep restriction
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
18 Years to 70 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 28, 2009 · Synced Jul 23, 2026, 1:29 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effect of Resistance Training on Tobacco-Related Cardiovascular Disease Risk

NCT01705951
View directory record Official record
Conditions
Smoking, Cardiovascular Disease Risk
Interventions
Resistance Training (RT), Nicotine Replacement Therapy (NRT)
Other · Biological
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 35 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 11, 2012 · Synced Jul 23, 2026, 1:29 PM EDT
Completed No phase listed Observational

The Effect of Obesity on Lung Functioning

NCT00284895
View directory record Official record
Conditions
Obesity, Asthma
Interventions
Not listed
Lead sponsor
National Jewish Health
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Jul 23, 2026, 1:29 PM EDT
Active, not recruiting Phase 1 Interventional

A Study to Evaluate the Effect of Maridebart Cafraglutide on Insulin Sensitivity and β-cell Function in Participants With Type 2 Diabetes Mellitus

NCT07160257
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Maridebart cafraglutide, Placebo
Drug
Lead sponsor
Amgen
Industry
Eligibility
18 Years to 70 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Jul 23, 2026, 1:29 PM EDT
Enrolling by invitation Phase 2 Interventional

The Effect of Osteoporotic Medications on Vertebral Bone Quality Score

NCT07587775
View directory record Official record
Conditions
Lumbar Degenerative Disease
Interventions
Abaloparatide
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
50 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Jul 23, 2026, 1:29 PM EDT
Terminated Phase 2 Interventional Results available

A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi Anemia

NCT03600909
View directory record Official record
Conditions
Fanconi Anemia, Myelodysplastic Syndrome (MDS), Acute Myelogenous Leukemia (AML)
Interventions
Busulfan, Fludarabine, Cyclophosphamide, Anti-Thymocyte Globulin (Rabbit), The CliniMACS device, G-CSF
Drug · Device
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
1 Month and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
3
States / cities
New York, New York • Cincinnati, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging

NCT03818802
View directory record Official record
Conditions
Healthy Elderly Volunteers
Interventions
Nicotinamide Riboside, Placebo
Dietary Supplement
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years to 80 Years · Female only
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 25, 2025 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 3 Interventional Results available

Saxagliptin + Metformin Compared to Saxagliptin or Metformin Monotherapy in PCOS Women With Impaired Glucose Homeostasis

NCT02022007
View directory record Official record
Conditions
Polycystic Ovary Syndrome, Disorder of Glucose Regulation
Interventions
Metformin XR, Saxagliptin, Saxagliptin-Metformin XR
Drug
Lead sponsor
Woman's
Other
Eligibility
18 Years to 42 Years · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Effect of Vitamin D Replacement on Insulin Sensitivity

NCT01268111
View directory record Official record
Conditions
Insulin Sensitivity
Interventions
Ergocalciferols, Placebo
Drug
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years to 60 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Odessa, Texas
Source: ClinicalTrials.gov public record
Updated Jun 7, 2015 · Synced Jul 23, 2026, 1:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Peanut Butter on Gut and Metabolic Health

NCT06916936
View directory record Official record
Conditions
Dysbiosis
Interventions
Creamy Richards 100% Peanuts! Creamy Natural Peanut Butter, Cadbury Milk Chocolate Spread
Other
Lead sponsor
Florida State University
Other
Eligibility
6 Years to 13 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Tallahassee, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 23, 2026, 1:29 PM EDT
Terminated Not applicable Interventional Results available

Metformin for Weight Loss in Schizophrenia

NCT01177709
View directory record Official record
Conditions
Schizophrenia, Obesity
Interventions
Metformin
Drug
Lead sponsor
Nathan Kline Institute for Psychiatric Research
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 31, 2017 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluation of Metabolism-Boosting Beverages

NCT01029236
View directory record Official record
Conditions
Energy Expenditure, Appetite
Interventions
Medifast Metabolism-boosting Beverages
Other
Lead sponsor
Medifast, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Owings Mills, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 8, 2009 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Essential Amino Acid Intake on Net Protein Synthesis in Weight-losing Non-small Cell Lung Cancer Patients

NCT01172314
View directory record Official record
Conditions
Non-small Cell Lung Cancer
Interventions
EAA+LEU vs total AA, Total AA vs EAA+LEU
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
40 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 2 Interventional

Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia

NCT01327014
View directory record Official record
Conditions
Hyperlipidemia
Interventions
XueZhiKang (XZK), a botanic product with multiple components, Placebo
Drug
Lead sponsor
Beijing Peking University WBL Biotech Co., Ltd.
Industry
Eligibility
18 Years and older
Enrollment
116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
8
States / cities
Beverly Hills, California • Hollywood, Florida • Kansas City, Kansas + 5 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2014 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Amino Acid Profile on Lipoprotein Metabolism, Vascular Reactivity and Inflammatory Markers

NCT00175084
View directory record Official record
Conditions
Hyperlipidemias, Metabolic Syndrome X, Cardiovascular Diseases
Interventions
Comparison of dietary protein amino acid profile
Behavioral
Lead sponsor
Tufts University
Other
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 4 Interventional Results available

Effect of Sitagliptin and an ACE Inhibitor on Blood Pressure in Metabolic Syndrome

NCT00666848
View directory record Official record
Conditions
Metabolic Syndrome, Hypertension
Interventions
Placebo, Enalapril 5mg, Enalapril 10mg, Sitagliptin
Drug
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 10, 2012 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Vitamin B6 Effects for Women Taking Birth Control Pills

NCT01128244
View directory record Official record
Conditions
Vitamin B6 Deficiency
Interventions
Vitamin B6, Infusion of labeled serine, methionine and leucine
Dietary Supplement · Procedure
Lead sponsor
University of Florida
Other
Eligibility
20 Years to 40 Years · Female only
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 6, 2017 · Synced Jul 23, 2026, 1:29 PM EDT
Completed Not applicable Interventional

FRESH-DOSE: Families Responsibility Education Support Health-Dual Options for Sustained Effectiveness

NCT03096132
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Family Based Behavioral Treatment, Guided Self-Help Fam. Based Bx Treatment
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
7 Years to 12 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated May 14, 2023 · Synced Jul 23, 2026, 1:29 PM EDT