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ClinicalTrials.gov public records Last synced Nov 15, 2026, 12:01 AM EST

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Showing 361–384 of 3,460 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Metabolic Effects Clear all

Conditions: Cocaine Dependence
Interventions: cocaine, hydrocortisone; Drug
Lead sponsor: National Institute on Drug Abuse (NIDA); NIH
Eligibility: 21 Years to 49 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Adrenal Hyperplasia, Congenital
Interventions: Not listed
Lead sponsor: Office of Rare Diseases (ORD); NIH
Eligibility: 12 Years and older
Enrollment: 233 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 2
States / cities: New York, New York • Dallas, Texas

Conditions: Obesity
Interventions: Survodutide, Semaglutide; Drug
Lead sponsor: Boehringer Ingelheim; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 64 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 2
States / cities: Orlando, Florida • Baton Rouge, Louisiana

Conditions: Metabolism and Nutrition Disorder, Obesity
Interventions: liraglutide, placebo; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 6 Years to 18 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 5
States / cities: Santa Monica, California • Baltimore, Maryland • Buffalo, New York + 2 more

Conditions: Ketogenic Dieting, Ketoses, Metabolic, Ketosis
Interventions: Well-formulated Ketogenic Diet; Behavioral
Lead sponsor: University of Kansas Medical Center; Other
Eligibility: 30 Years to 55 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 1
States / cities: Kansas City, Kansas

Conditions: Healthy, Ketogen-based Therapeutic Diet, Metabolic Abnormalities
Interventions: Diet; Other
Lead sponsor: The University of Tennessee at Martin; Other
Eligibility: 18 Years and older
Enrollment: 79 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Martin, Tennessee

Conditions: Obesity, Hyperlipidemia, Insulin Resistance, Hypertension
Interventions: Glutathione, N-Acetylcysteine, Placebo; Dietary Supplement · Other
Lead sponsor: Stanford University; Other
Eligibility: 18 Years and older
Enrollment: 78 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Stanford, California

Conditions: Energy Metabolism, Heart Rate, Blood Pressure, Mood
Interventions: Sugar Pill (placebo), Caffeine (plus Teacrine and Cayenne), Caffeine (plus Teacrine); Drug · Dietary Supplement
Lead sponsor: University of Mary Hardin-Baylor; Other
Eligibility: 18 Years to 35 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Belton, Texas

Conditions: Coronary Disease, Diabetes Mellitus
Interventions: torcetrapib/atorvastatin, atorvastatin; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 45 Years to 75 Years
Enrollment: 15,067 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2007
U.S. locations: 95
States / cities: Alabaster, Alabama • Birmingham, Alabama • Gilbert, Arizona + 92 more

Conditions: Diabetes Mellitus, Type 2
Interventions: Group-based Cognitive Behavioral Intervention, Web-based Cognitive Behavioral Intervention, Usual Care; Behavioral
Lead sponsor: Emory University; Other
Eligibility: 18 Years and older
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Atlanta, Georgia

Conditions: Weight Loss, Obesity
Interventions: behavioral weight loss; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years to 55 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Diabetes, Diabetes Mellitus, Type 2, Renal Impairment
Interventions: semaglutide; Drug
Lead sponsor: Novo Nordisk A/S; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 62 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2010
U.S. locations: 3
States / cities: Miami, Florida • Orlando, Florida • Knoxville, Tennessee

Conditions: Pregnancy Related, Physical Activity
Interventions: Active, Sedentary; Behavioral
Lead sponsor: Pennington Biomedical Research Center; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2020
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Overweight, Cardiovascular Diseases
Interventions: Low Fat and High Carbohydrate Diet, High Fat and Low Carbohydrate Diet; Behavioral
Lead sponsor: Brigham and Women's Hospital; Other
Eligibility: 21 Years to 75 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Hyperkalemia
Interventions: Sodium Zirconium Cyclosilicate (SZC), SZC Placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 130 Years
Enrollment: 2,690 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2024
U.S. locations: 57
States / cities: Huntsville, Alabama • Mesa, Arizona • Bakersfield, California + 47 more

Conditions: Iron Overload, Oxidative Stress, Iron-deficiency Anemia
Interventions: Iron, Placebo; Dietary Supplement
Lead sponsor: University of California, Davis; Other
Eligibility: 18 Years and older · Female only
Enrollment: 114 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2010
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Type 2 Diabetes Mellitus
Interventions: exenatide, placebo; Drug
Lead sponsor: AstraZeneca; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 196 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2008
U.S. locations: 10
States / cities: Peoria, Arizona • Jacksonville, Florida • Orlando, Florida + 7 more

Conditions: Diabetes Mellitus
Interventions: Insulin Detemir, Insulin Glargine; Drug
Lead sponsor: University of New Mexico; Other
Eligibility: 18 Years to 60 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 1
States / cities: Albuquerque, New Mexico

Conditions: Obesity, Metabolic Syndrome X, Hyperlipidemia, Hypertension
Interventions: Almond enriched diet, Low fat caloric diet; Behavioral
Lead sponsor: Temple University; Other
Eligibility: 18 Years to 75 Years
Enrollment: 123 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Congenital Hyperinsulinism
Interventions: Exendin (9-39), Vehicle; Drug
Lead sponsor: Diva De Leon; Other
Eligibility: Up to 12 Months
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Morbid Obesity, Non-alcoholic Fatty Liver Disease
Interventions: low carbohydrate diet, low-fat diet; Other
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 55 Years
Enrollment: 31 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2012
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Type 2 Diabetes Mellitus
Interventions: Placebo, Dulaglutide, Glimepiride; Drug
Lead sponsor: Eli Lilly and Company; Industry
Eligibility: 18 Years and older
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 6
States / cities: Chino, California • Miami, Florida • St Louis, Missouri + 3 more

Conditions: Hypercholesterolemia
Interventions: Disodium Ascorbyl Phytostanol Phosphate (FM-VP4); Drug
Lead sponsor: Forbes Medi-Tech; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 150 participants
Timeline: Started 2005
U.S. locations: 14
States / cities: Mobile, Alabama • San Diego, California • Daytona Beach, Florida + 10 more

Conditions: Insulin Resistance
Interventions: Hi-maize starch (Low dose), Hi-maize starch (High-dose), Control (starch); Other
Lead sponsor: Ingredion Incorporated; Industry
Eligibility: 18 Years to 69 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Glen Ellyn, Illinois

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Metabolic Effects of Cocaine

Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their Mothers

A Study to Test Whether Survodutide Improves How the Body Uses Energy and Breaks Down Fat in People With Obesity

Effect of Liraglutide for Weight Management in Paediatric Subjects With Prader-Willi Syndrome

Ketogenic Diet Health and Longevity

Comparing Intermittent Fasting, Clean Ketogenic Diet, and Their Combined Effects on Body Composition, Cardiometabolic Markers, and Metabolic Health

Effects of Glutathione (an Antioxidant) and N-Acetylcysteine on Inflammation

Effects of a Thermogenic Dietary Supplement on Metabolic, Hemodynamic, and Mood Responses

A Study Examining Torcetrapib/Atorvastatin And Atorvastatin Effects On Clinical CV Events In Patients With Heart Disease

Cognitive Behavioral Therapy for African Americans With Uncontrolled Type-2 Diabetes

The Effect of HealthWear on Short-Term Weight Loss

Effect of Renal Impairment on the Pharmacokinetics of NN9535

Mitochondrial Capacity in Pregnant Women

Dietary Fat and High-Density Lipoprotein (HDL) Metabolism-Effect of Carbohydrate and Fat Intake

Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

Effects of Taking Prenatal Vitamin-mineral Supplements During Lactation on Iron Status and Markers of Oxidation

Effect on Weight Loss of Exenatide Versus Placebo

Insulin Detemir Compared to Insulin Glargine: Appetite and Calories Consumed in Type 1 Diabetes

Weight and Metabolic Effects of an Almond Enriched Hypocaloric, Low Fat Diet on Overweight and Obese Persons

Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia

Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates

Study of How Dulaglutide Compares to Placebo in Participants With Type 2 Diabetes Who Are Also on Sulfonylurea Therapy (AWARD-8)

Study on the Safety and Effects on Lipids of FM-VP4 in Subjects With Primary Hypercholesterolemia

Effects of Hi-maize Resistant Starch on Insulin Sensitivity