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ClinicalTrials.gov public records Last synced Nov 9, 2026, 12:10 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 169–192 of 201 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Metabolic Regulation Clear all

Conditions: Obesity and Type 2 Diabetes, Diet Modification
Interventions: Regulation of craving training; Behavioral
Lead sponsor: University of Wyoming; Other
Eligibility: 15 Years to 18 Years · Female only
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: Laramie, Wyoming

Conditions: Dyslipidemia
Interventions: Atorvastatin, ABT335, ER Niacin; Drug
Lead sponsor: University of Pennsylvania; Other
Eligibility: 18 Years to 80 Years
Enrollment: 25 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Obesity, Insulin Resistance
Interventions: placebo, pioglitazone; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 80 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Atherosclerosis
Interventions: Not listed
Lead sponsor: Vanderbilt University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 50 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2007 – 2011
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Obesity
Interventions: Parents of Preschoolers Series, Incredible Years Series; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 2 Years to 6 Years
Enrollment: 697 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Type 2 Diabetes Mellitus
Interventions: Human insulin; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 30 Years to 65 Years
Enrollment: 14 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012
U.S. locations: 1
States / cities: Scottsdale, Arizona

Conditions: Pediatric Obesity, Executive Function
Interventions: Web Based Treatment; Behavioral
Lead sponsor: University of Alabama at Birmingham; Other
Eligibility: 8 Years to 14 Years
Enrollment: 19 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Birmingham, Alabama

Conditions: Branched-chain Amino Acid Metabolism, Insulin Sensitivity
Interventions: Pre-Diabetes Group - 6-mo Aerobic and Resistance combined exercise training, GBP Group - Non-diabetics intending to undergo Gastric Bypass surgery; Other
Lead sponsor: Duke University; Other
Eligibility: 30 Years to 65 Years
Enrollment: 132 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Diabetes Mellitus, Diabetic Retinopathy
Interventions: Melatonin, Placebo; Drug · Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 40 Years to 65 Years
Enrollment: 42 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Aging, Insulin Sensitivity, Chronic Disease, Mitochondria, Insulin Resistance
Interventions: Metformin, Placebo oral tablet; Drug
Lead sponsor: Oklahoma Medical Research Foundation; Other
Eligibility: 40 Years to 75 Years
Enrollment: 166 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2025
U.S. locations: 2
States / cities: Oklahoma City, Oklahoma • Madison, Wisconsin

Conditions: Obesity
Interventions: overfeeding, growth hormone treatment; Other · Drug
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years to 35 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2005 – 2015
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Metabolic Side Effects of Drugs
Interventions: SULT Allosteric Inhibition; Drug
Lead sponsor: Albert Einstein College of Medicine; Other
Eligibility: 61 Years to 61 Years · Male only
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2023
U.S. locations: 1
States / cities: The Bronx, New York

Conditions: Obesity
Interventions: Protein powder supplement, standard dosage based on 0.5 gram protein per pound of subject's lean body mass, Protein powder supplement, High Level Protein, based on 1 gram of protein per pound of lean body mass: 25% protein and 45% carbohydrate; Dietary Supplement
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 30 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2019
U.S. locations: 1
States / cities: West Los Angeles, California

Conditions: Appetite Regulation, Obesity
Interventions: Exendin-(9-39) Acetate, Saline 0.9%; Drug
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 29 Years
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Prader-Willi Syndrome
Interventions: Octreotide, Placebo; Drug
Lead sponsor: Duke University; Other
Eligibility: 5 Years to 21 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2010
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Type 2 Diabetes, Binge Eating
Interventions: DSME + ASE intervention (Centering Appetite); Behavioral
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 18 Years to 75 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2025 – 2027
U.S. locations: 2
States / cities: Kannapolis, North Carolina

Conditions: Healthy, Healthy Volunteers
Interventions: LCHF diet, LFHC diet; Dietary Supplement
Lead sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Hyperglycaemia (Non Diabetic), Prediabetes
Interventions: Lean Pork vs Plant-Based Protein; Other
Lead sponsor: University of Arkansas; Other
Eligibility: 40 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Little Rock, Arkansas

Conditions: Aging, Healthy, Blood Sugar; High, Blood Sugar (Glucose) Control, Time Restricted Eating, Circadian Dysregulation
Interventions: Circadian Rhythm Optimization; Behavioral
Lead sponsor: Salk Institute for Biological Studies; Other
Eligibility: 50 Years to 80 Years
Enrollment: 16 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2026
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Obesity, Depression
Interventions: I-CARE2; Behavioral
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 18 Years and older
Enrollment: 106 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 2
States / cities: Chicago, Illinois

Conditions: Metabolic Regulation, Fasting, Ketogenic Diet
Interventions: Dietary manipulation ketogenic diet, Dietary Manipulation - 12 day ketogenic diet, 16 Hour Fast; Behavioral
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Type 2 Diabetes, Obesity
Interventions: DvtProgram ENERGY, DvtProgramENERGY; Behavioral
Lead sponsor: Colorado State University; Other
Eligibility: 6 Years to 13 Years
Enrollment: 1,703 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2008
U.S. locations: 2
States / cities: Cortez, Colorado • Fort Collins, Colorado

Conditions: Hypercholesterolemia, Coronary Heart Disease
Interventions: Different amount of phytosterols are added into diets; Dietary Supplement
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 80 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Overweight and Obesity, Physical Activity, Weight Change, Body, Eating Behavior
Interventions: Intervention group, Control group; Behavioral
Lead sponsor: Penn State University; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: University Park, Pennsylvania

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Mobile Regulation of Craving Training (mROC-T) to Improve Dietary Intake in Rural Adolescent Girls

Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study

Ghrelin Regulation and Structure: Effect of Thiazolidinedione Therapy on Ghrelin

Characterizing PAI-1 Modulation on Monocyte Adhesion

Enhancing Self Regulation as a Strategy for Obesity Prevention in Head Start Preschoolers

Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance

Virtual Health Focused Acceptance-Based Program for Parents and Youth

Regulation of Branched-chain Amino Acid Metabolism in Pre-Diabetes

Sleep, Diabetic Retinopathy and Melatonin

Antecedent Metabolic Health and Metformin Aging Study

Growth Hormone as a Determinant of Weight Regulation

Studies of Sulfur Metabolism in Humans

Gastrointestinal Hormonal Regulation of Obesity

The Role of GLP-1 in Satiety Perception in Humans

Octreotide Therapy in Children and Young Adults With Prader-Willi Syndrome (PWS)

Improving Appetite Self-Regulation in African American Adults With Type 2 Diabetes

Effects of Low Fat Versus Low Carbohydrate Diets on Energy Metabolism

Effects of Lean Pork Loin Intake on Protein Homeostasis and Glucose Regulation in Prediabetic Adults

Circadian Health Regulation and Optimization for Rejuvenation Outcomes

Engaging Self-regulation Targets to Improve Mood and Weight and Understand Mechanism in Depressed and Obese Adults

Effects of Dietary Manipulation on Metabolism in Healthy Adults

Diabetes Virtual Trek: Obesity and Diabetes Prevention Through Science Enrichment

Addition of Phytosterols to a Low Phytosterol Diet

Healthy Mom Zone: A Gestational Weight Gain Management Intervention