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ClinicalTrials.gov public records Last synced Oct 23, 2026, 10:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 601–624 of 1,515 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed No phase listed Observational

Continuous Glucose Monitoring (CGM) in Subjects With Type 2 Diabetes Taking Twice-Daily Exenatide or Once-Weekly Exenatide

NCT00803920
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Not listed
Lead sponsor
HealthPartners Institute
Other
Eligibility
16 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 3, 2015 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

CO-OP Trial: Community-based Outreach on Obesity in Pregnancy

NCT01841424
View directory record Official record
Conditions
Obesity, Pregnancy
Interventions
Dietary counseling. Maintain a food diary.
Behavioral
Lead sponsor
University of Missouri, Kansas City
Other
Eligibility
Female only
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
2
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feeding America's Bravest: Mediterranean Diet-Based Interventions to Change Firefighters' Eating Habits

NCT02941757
View directory record Official record
Conditions
Diet, Mediterranean, Health Behavior, Program Sustainability, Program Effectiveness
Interventions
Mediterranean diet Intervention
Behavioral
Lead sponsor
Harvard School of Public Health (HSPH)
Other
Eligibility
18 Years and older
Enrollment
486 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 14, 2020 · Synced Oct 23, 2026, 10:51 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Maternal Well-Being Study

NCT05484999
View directory record Official record
Conditions
Postpartum Depression, Postpartum Anxiety, Weight Retention, Postpartum, Nutritional and Metabolic Diseases
Interventions
Meals, Meals + Social Support, Control
Other
Lead sponsor
Texas Tech University Health Sciences Center
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Amarillo, Texas
Source: ClinicalTrials.gov public record
Updated Aug 29, 2024 · Synced Oct 23, 2026, 10:51 AM EDT
Terminated Not applicable Interventional Results available

Brain Energy Metabolism and Sleep in Adults

NCT03929302
View directory record Official record
Conditions
Alzheimer Disease, Mild Cognitive Impairment, Cognitive Change, Energy Metabolism, Sleep Disturbance
Interventions
MyTAP oral appliance plus mouth shield
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
55 Years to 85 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Grapefruit or Grapefruit Juice on Anthropometry, Dietary Intakes, Appetite, and Metabolic Profile in Overweight and Obese Young and Middle-Aged Adults

NCT00581074
View directory record Official record
Conditions
Obesity
Interventions
diet (grapefruit or grapefruit juice)
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
21 Years to 50 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 27, 2011 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Mobile Weight Loss Intervention for Adolescent and Young Adult Cancer Survivors

NCT06171945
View directory record Official record
Conditions
Cancer, Physical Activity, Cancer Survivorship, Mental Health, Obesity
Interventions
AYA Connect intervention, Positive Psychology (PP) intervention, Positive Psychology Plus (PP+) intervention
Behavioral
Lead sponsor
UNC Lineberger Comprehensive Cancer Center
Other
Eligibility
18 Years to 39 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Rethinking Eating and FITness for Men

NCT01843595
View directory record Official record
Conditions
Weight Loss, Overweight
Interventions
REFIT Intervention
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years · Male only
Enrollment
107 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 21, 2014 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults

NCT00518466
View directory record Official record
Conditions
Obesity
Interventions
topiramate, phentermine
Drug
Lead sponsor
VIVUS LLC
Industry
Eligibility
19 Years to 65 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2011 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

GoalTracker: Comparing Self-Monitoring Strategies for Weight Loss

NCT03254953
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss
Interventions
self-monitoring of body weight, self-monitoring of diet, weekly personalized feedback + lessons + action plans
Behavioral
Lead sponsor
Duke University
Other
Eligibility
21 Years to 65 Years
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Oct 23, 2026, 10:51 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Weight Loss Using a Feedback Device in Obese People With the Metabolic Syndrome

NCT03491930
View directory record Official record
Conditions
Weight Loss, Obesity, Pre-Diabetes, Metabolic Syndrome
Interventions
VA MOVE! Coach app, Telephone Coaching, Standard of Care for weight loss.
Device · Behavioral
Lead sponsor
Rockefeller University
Other
Eligibility
40 Years to 70 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 24, 2018 · Synced Oct 23, 2026, 10:51 AM EDT
Terminated Phase 1Phase 2 Interventional

A Phase I/II Open-Label Dose-Escalation Clinical Trial of CPI-613 in Combination With Gemcitabine in Cancer Patients

NCT00907166
View directory record Official record
Conditions
Cancer, Pancreatic Cancer, Pancreatic Carcinoma
Interventions
CPI-613, Gemcitabine
Drug
Lead sponsor
Cornerstone Pharmaceuticals
Industry
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
2
States / cities
The Bronx, New York • Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

ClockWork Postpartum Weight Management Study

NCT04992637
View directory record Official record
Conditions
Obesity, Postpartum Weight Retention, Weight Gain, Maternal
Interventions
ClockWork, Usual Care
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older · Female only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 3, 2023 · Synced Oct 23, 2026, 10:51 AM EDT
Recruiting Phase 4 Interventional

Individualized Pharmacological Approach to Obesity in Patients With Bipolar Disorder

NCT07213466
View directory record Official record
Conditions
Bipolar I Disorder, Bipolar II Disorder, Schizo Affective Disorder, Obesity, Weight Loss, GLP - 1
Interventions
Group Therapy Program, semaglutide, Phentermine-Topiramate, naltrexone and bupropion (combination)
Behavioral · Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Assessing Risk for Osteoporosis on Physician and Patient Behaviors

NCT01572766
View directory record Official record
Conditions
Osteoporosis, Osteopenia
Interventions
FRAX Assessment Tool
Other
Lead sponsor
Duquesne University
Other
Eligibility
45 Years to 65 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2012 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Diabetes Prevention Among Post-partum Women With History of Gestational Diabetes

NCT02240420
View directory record Official record
Conditions
Gestational Diabetes Mellitus, Type 2 Diabetes Mellitus
Interventions
Life Style Counseling (Star-Mama)
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 39 Years · Female only
Enrollment
181 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Feb 11, 2021 · Synced Oct 23, 2026, 10:51 AM EDT
Active, not recruiting No phase listed Observational

Glycemic Control, Type II Diabetes, Parathyroidectomy

NCT05761743
View directory record Official record
Conditions
Primary Hyperparathyroidism, Type 2 Diabetes
Interventions
Urine and Blood Test
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

A High Protein Weight Loss Intervention for Sarcopenic Obesity in Women

NCT02033655
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Protein supplementation, Diet counseling and group education lessons
Dietary Supplement · Behavioral
Lead sponsor
Duke University
Other
Eligibility
45 Years and older · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2019 · Synced Oct 23, 2026, 10:51 AM EDT
Active, not recruiting Phase 1 Interventional

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

NCT07399678
View directory record Official record
Conditions
Overweight or Obese Adults, Overweight or Obese, Type 2 Diabetes
Interventions
ALV-100, Placebo
Drug
Lead sponsor
Alveus Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Miami, Florida • Columbus, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Glycemic Index and Brain Function

NCT01064778
View directory record Official record
Conditions
Obesity
Interventions
Low GI, High GI
Other
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
3
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 2, 2012 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Not applicable Interventional

Interaction of Cobalamin Status With Nitrous Oxide in Relation to Postoperative Cognitive Changes in the Elderly

NCT00212147
View directory record Official record
Conditions
Avitaminosis, Delirium, Dementia, Amnestic, Cognitive Disorders
Interventions
General anesthesia with nitrous oxide, General anesthesia without nitrous oxide
Drug
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
60 Years and older
Enrollment
444 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2008
U.S. locations
2
States / cities
Brooklyn, New York • New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Effect of HealthWear on Short-Term Weight Loss

NCT00177593
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
behavioral weight loss
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 55 Years
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Oct 23, 2026, 10:51 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Effects of Adding L-BAIBA to Exercising Adult Overweight and Obese Men and Women

NCT05775016
View directory record Official record
Conditions
Obesity, Weight Loss, Weight, Body, Cardiometabolic Syndrome
Interventions
Exercise
Behavioral
Lead sponsor
Lindenwood University
Other
Eligibility
18 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Saint Charles, Missouri
Source: ClinicalTrials.gov public record
Updated Jul 29, 2024 · Synced Oct 23, 2026, 10:51 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Enhancing Weight Loss Maintenance With GLP-1RA (BYDUREON™) in Adolescents With Severe Obesity

NCT02496611
View directory record Official record
Conditions
Severe Obesity
Interventions
Weight loss with pharmacotherapy, Weight loss without pharmacotherapy
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 17 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 3, 2022 · Synced Oct 23, 2026, 10:51 AM EDT