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ClinicalTrials.gov public records Last synced Oct 24, 2026, 2:41 AM EDT

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Showing 721–744 of 1,515 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed Not applicable Interventional

Study of Duodenal-Jejunal Bypass(DJB) as a Potential Cure for Type 2 Diabetes Mellitus

NCT00562029
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
Duodenal-jejunal Bypass
Procedure
Lead sponsor
Sound Shore Medical Center of Westchester
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
New Rochelle, New York
Source: ClinicalTrials.gov public record
Updated May 21, 2015 · Synced Oct 24, 2026, 2:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Gene Expression and Inflammation in Overweight Subjects

NCT00344266
View directory record Official record
Conditions
Obesity, Inflammation, Nutrition Therapy
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
25 Years to 45 Years
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 17, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Not listed No phase listed Observational

Clinical Specimen Collection From Pompe Disease Patients

NCT04476550
View directory record Official record
Conditions
Pompe Disease
Interventions
Filgrastim
Drug
Lead sponsor
Serhat Gumrukcu, MD PhD
Other
Eligibility
3 Years to 30 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Toluca Lake, California
Source: ClinicalTrials.gov public record
Updated May 19, 2022 · Synced Oct 24, 2026, 2:41 AM EDT
Not listed Not applicable Interventional

Cardiometabolic Syndrome Response to Therapeutic Lifestyle Changes

NCT04093440
View directory record Official record
Conditions
Metabolic Syndrome, ASCVD, Lifestyle Risk Reduction
Interventions
lifestyle modification
Other
Lead sponsor
Holy Cross Hospital, Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Sep 18, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Active, not recruiting Not applicable Interventional

Plant-based Diet for Kidney Transplant Recipients

NCT06186843
View directory record Official record
Conditions
Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus, Metabolic Syndrome, Inflammation, Kidney Transplant Failure, Dietary Habits
Interventions
Plant-based diet
Behavioral
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Lean Living Study

NCT02501889
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Walnut-rich weight loss diet, Standard weight loss diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Results available

Laparoscopic Sleeve Gastrectomy With Endoscopic Visualization

NCT00911989
View directory record Official record
Conditions
Morbid Obesity
Interventions
NOTES toolbox
Device
Lead sponsor
Ethicon Endo-Surgery
Industry
Eligibility
21 Years to 60 Years · Female only
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 25, 2012 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Single-Group Study to Examine the Efficacy of a Gut Health Supplement to Increase Metabolism, Improve Gut Health, and Support Weight Management

NCT06023082
View directory record Official record
Conditions
Gut Health, Metabolism, Weight Loss, Energy
Interventions
Colon Broom Premium supplement
Dietary Supplement
Lead sponsor
Gut Health, UAB
Industry
Eligibility
30 Years to 50 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 24, 2026, 2:41 AM EDT
Completed No phase listed Observational

Small Bowel Length and Bariatric Surgery Outcomes

NCT02872493
View directory record Official record
Conditions
Malnutrition, Obesity, Weight Loss, Micronutrient Deficiency
Interventions
Small bowel length measurement
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
470 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Get Active and Eat Right: Moms at Work

NCT01668316
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Weight loss
Behavioral
Lead sponsor
University of North Carolina, Greensboro
Other
Eligibility
18 Years and older · Female only
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Greensboro, North Carolina
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

New DIETs: New Dietary Interventions Enhancing the Treatment for Weight Loss

NCT01742572
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Diet
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Completed No phase listed Observational

The Collateral Impact of Bariatric Surgery on Families

NCT02021630
View directory record Official record
Conditions
Obesity, Bariatric Surgery Candidate, Weight Loss
Interventions
Outcomes
Other
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional

Stay In Treatment for Pediatric Weight Management

NCT04364282
View directory record Official record
Conditions
Pediatric Obesity, Attrition, Family Research, Weight Loss
Interventions
Care team informed, Control
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
7 Years and older
Enrollment
1,216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
2
States / cities
Kansas City, Missouri • Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 24, 2026, 2:41 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Predictors of Lorcaserin-Induced Weight Loss

NCT03353220
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Belviq, Placebo
Drug
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 60 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 27, 2024 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Internet Weight Control for Bingeing Adolescents

NCT00125112
View directory record Official record
Conditions
Obesity, Eating Disorders
Interventions
Internet-based intervention designed to reduce binge eating and improve healthy weight regulation
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
14 Years to 18 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jan 18, 2010 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Phone Coaching for Weight Loss Maintenance

NCT04293055
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Maintenance program, Phone coaching
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 72 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Dec 31, 2024 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Phase 3 Interventional

Obese Patients With or Without Comorbidities (RIO-North America)

NCT00029861
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
3,045 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Concord, California + 42 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2009 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Phase 2 Interventional Results available

A Multi-Center Study in Men With Acquired Hypogonadotropic Hypogonadism to Compare Changes in Body Composition and Metabolic Parameters With Diet and Exercise in Conjunction With Treatment With 12.5 mg or 25 mg Enclomiphene

NCT02651688
View directory record Official record
Conditions
Acquired Hypogonadotropic Hypogonadism, Obesity
Interventions
Placebo, Enclomiphene
Drug
Lead sponsor
Repros Therapeutics Inc.
Industry
Eligibility
18 Years to 60 Years · Male only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
5
States / cities
Albany, New York • Garden City, New York • Providence, Rhode Island + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 27, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Gastric Artery Embolization Trial for Lessening Appetite Nonsurgically

NCT02248688
View directory record Official record
Conditions
Arterial Embolization, Other Surgical Procedures, Obesity
Interventions
BeadBlock 300 - 500 Micron, Left Gastric Artery Embolization
Device · Procedure
Lead sponsor
Dayton Interventional Radiology
Other
Eligibility
22 Years to 65 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Family-Based Weight Loss Intervention for Youth With Intellectual Disability

NCT02033642
View directory record Official record
Conditions
Obesity
Interventions
Family Based Behavioral Intervention, Maintenance
Behavioral
Lead sponsor
University of Massachusetts, Boston
Other
Eligibility
14 Years to 22 Years
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese

NCT06567327
View directory record Official record
Conditions
Obesity
Interventions
Danuglipron, Atorvastatin, Rosuvastatin
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years to 64 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
3
States / cities
Anaheim, California • South Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 6, 2025 · Synced Oct 24, 2026, 2:41 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation of Modified Adhesives With Dexcom G6 Sensor

NCT04840446
View directory record Official record
Conditions
Diabetes
Interventions
Dexcom Continuous Glucose Monitoring System
Device
Lead sponsor
DexCom, Inc.
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2021 · Synced Oct 24, 2026, 2:41 AM EDT
Recruiting Not applicable Interventional

Using Continuous Glucose Monitoring to Quantify the Effects of NOURISH's Culturally Modified Meals on Asian Americans With Type 2 Diabetes

NCT06836479
View directory record Official record
Conditions
Type 2 Diabetes Mellitus (T2DM), Type 2 Diabetes
Interventions
NOURISH Diet, Self-Selected Diet (Control)
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 24, 2026, 2:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss

NCT00108524
View directory record Official record
Conditions
Diabetes Mellitus, Obesity
Interventions
Low carbohydrate ketogenic diet, Orlistat, Low-fat diet
Behavioral · Drug
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 69 Years
Enrollment
146 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2014 · Synced Oct 24, 2026, 2:41 AM EDT