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Showing 913–936 of 1,515 matching trials from the live ClinicalTrials.gov search.
Completed Phase 2 Interventional Accepts healthy volunteers

Safety and Efficacy of APD356 in the Treatment of Obesity

NCT00116740
Conditions
Obesity
Interventions
APD356
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Conditions
Obesity
Interventions
Social Network Intervention, Individual Lifestyle Intervention, Social Network Member
Behavioral · Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
264 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
New York, New York
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Impact of Aripiprazole Once Monthly Medications on Changes in Brain Structure and Metabolism

NCT02237417
Conditions
Schizophrenia
Interventions
Standard of Care Oral antipsychotics, IM aripiprazole once monthly, No Treatment
Drug · Other
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Type 2 Diabetes
Interventions
Digital Photography of meals/snacks and group discussion
Behavioral
Lead sponsor
Joslin Diabetes Center
Other
Eligibility
30 Years to 60 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers

Alcohol in the Treatment of Obesity

NCT00594074
Conditions
Obesity, Weight Loss, Alcohol Drinking
Interventions
white wine
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older · Female only
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Insulin Resistance, Depression
Interventions
Health-Related Quality of Life instrument, Depression Scale for Children (CES-DC)
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
11 Years to 17 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Kansas City, Missouri
Conditions
Demyelinating Diseases, Demyelination; Corpus Callosum, Multiple Sclerosis Brain Lesion, Multiple Sclerosis Acute and Progressive, Clinically Isolated Syndrome, CNS Demyelinating
Interventions
Clemastine Fumarate, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
San Francisco, California
Active, not recruiting Not applicable Interventional

Low GI Diet in Children and Adolescents With ALL

NCT03157323
Conditions
Acute Lymphoblastic Leukemia, Pediatric, Obesity, Pediatric
Interventions
Low Glycemic Index Diet
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
5 Years to 21 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2026
U.S. locations
5
States / cities
Hartford, Connecticut • Washington D.C., District of Columbia • Buffalo, New York + 2 more
Conditions
Weight Loss, Diet Habit, Physical Activity, Overweight and Obesity
Interventions
Koa Family
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 47 Years · Female only
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Sacramento, California
Terminated Not applicable Interventional Accepts healthy volunteers

microRNA Testing for Identification of Personalized Weight Management

NCT04217850
Conditions
Overweight and Obesity, Weight Loss
Interventions
250 kcal Dietary Energy Restriction, Aerobic Exercise
Other
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 60 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fargo, North Dakota
Completed Not applicable Interventional Accepts healthy volunteers

Coached or Non-Coached Weight Loss Intervention

NCT04645108
Conditions
Obesity, Behavior, Health, Behavior, Eating, Weight Loss, Overweight and Obesity, Self Efficacy
Interventions
Noom Healthy Weight; mobile behavior change program for weight loss with 1:1 coaching, Noom Healthy Weight; mobile behavior change program for weight loss
Behavioral
Lead sponsor
Noom Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
246 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
New York, New York
Conditions
Diabetes, Insulin
Interventions
insulin dose software
Device
Lead sponsor
HealthPartners Institute
Other
Eligibility
21 Years to 70 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Conditions
Gestational Diabetes
Interventions
Lifestyle Counseling
Behavioral
Lead sponsor
Kaiser Permanente
Other
Eligibility
20 Years to 45 Years · Female only
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Oakland, California
Conditions
Delirium, Confusion, Mental Status Change, Back Pain, Hip Pain Chronic, Chest Pain, Asthma, COPD, Cellulitis, Soft Tissue Infections, Cough, Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboembolism, Dyspnea, Electrolyte Metabolism Abnormal, Fever, Failure to Thrive, Weakness, Protein-Calorie Malnutrition, Headache, Neck Pain, Hypoxia, Pneumonia, Sepsis, Syncope, Vomiting, Diarrhea, Leg Pain, Abdominal Pain
Interventions
Diagnostic Uncertainty Educational Curriculum, Diagnostic Timeout, Patient Diagnostic (Dx) Questionnaire, Enhancements to Epic-integrated Quality & Safety Dashboard
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Conditions
Healthy, Mood Disorder
Interventions
Hypericum (LI-160)
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1999 – 2002
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Weight Loss, Pediatric Obesity
Interventions
iAmHealthy Parents First, iAmHealthy
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
6 Years and older
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Kansas City, Kansas
Conditions
Osteoporosis
Interventions
Diet with increased fruits, vegetables, and calcium, Increased high impact activity and resistance training
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
14 Years to 16 Years · Female only
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2003
U.S. locations
1
States / cities
Portland, Oregon
Completed Phase 4 Interventional Accepts healthy volunteers

The Safety and Efficacy of Low and High Carbohydrate Diets

NCT00143936
Conditions
Obesity
Interventions
Low- Carbohydrate -Atkins Diet, Low Calorie Diet
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 65 Years
Enrollment
360 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Conditions
Overweight and Obesity, Body Weight Changes, Healthy Lifestyle, Exercise, Dietary Supplement
Interventions
Phaeosol group, Placebo group
Dietary Supplement
Lead sponsor
Microphyt
Industry
Eligibility
18 Years to 50 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
College Station, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Renal Considerations in the Heat Stress Recommendations

NCT04767347
Conditions
Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia, Dehydration
Interventions
23.0°C WBGT - Fixed Work Rate, 25.5°C WBGT - Fixed Work Rate, 27.5°C WBGT - Fixed Work Rate, 28.5°C WBGT - Fixed Work Rate, 35.5°C WBGT - Fixed Work Rate, 26.0°C WBGT - Fixed work-to-rest ratio, 30.5°C WBGT - Fixed work-to-rest ratio, 30.5°C WBGT - Fixed work-to-rest ratio (high intensity)
Other
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Completed Not applicable Interventional Accepts healthy volunteers

Promoting Lifestyle Change Via Tailored mHealth Feedback to Improve Health

NCT03367936
Conditions
Overweight and Obesity
Interventions
One-on-one Session, Self-monitoring, Feedback
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
502 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Conditions
Obesity, Women (Between 30 to 60 Years Old)
Interventions
Protein Rich Foods
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
30 Years to 60 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Austin, Texas
Conditions
Body Weight Changes, Weight Loss, Healthy Diet, Obesity
Interventions
Video Conferencing Health Coaching with devices, Video Conferencing Health Coaching with no devices
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Conditions
Hormone Receptor-Positive Breast Cancer, HER2-Negative Breast Cancer
Interventions
Tirzepatide
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
7
States / cities
Elizabeth, New Jersey • Hamilton, New Jersey • Livingston, New Jersey + 4 more