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ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:38 AM EDT

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Showing 73–96 of 1,514 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed No phase listed Observational

Metabolic Changes in Blood Samples From Patients With Acute Myeloid Leukemia

NCT02581917
View directory record Official record
Conditions
Recurrent Adult Acute Myeloid Leukemia, Untreated Adult Acute Myeloid Leukemia
Interventions
Cytology Specimen Collection Procedure, Laboratory Biomarker Analysis
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 20, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

Diet and Exercise Intervention in Type 2 Diabetes

NCT01977560
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Intensive Lifestyle Intervention, Standard Care
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 68 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 15, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exercise After Clinically Significant Weight Loss

NCT03685123
View directory record Official record
Conditions
Obesity, Sedentary Lifestyle, Insulin Resistance
Interventions
Physical activity recommendations, Weight maintenance recommendations, OPTIFAST weight loss
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 3, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Results available

Implementing Effective, Collaborative Care for Schizophrenia (EQUIP-2)

NCT00137280
View directory record Official record
Conditions
Schizophrenia, Chronic Illness, Weight Gain, Psychotic Disorder
Interventions
Collaborative Chronic Illness Care Model
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
8
States / cities
Long Beach, California • West Los Angeles, California • Shreveport, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritional and Functional Changes in Heart Failure and COPD

NCT01787682
View directory record Official record
Conditions
Chronic Heart Failure, Chronic Obstructive Pulmonary Disorder
Interventions
BOOST High Protein
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
20 Years and older
Enrollment
99 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Feb 7, 2022 · Synced Oct 21, 2026, 5:38 AM EDT
Active, not recruiting Phase 1 Interventional

Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

NCT07399678
View directory record Official record
Conditions
Overweight or Obese Adults, Overweight or Obese, Type 2 Diabetes
Interventions
ALV-100, Placebo
Drug
Lead sponsor
Alveus Therapeutics, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
Miami, Florida • Columbus, Ohio • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Withdrawn Not applicable Interventional

Effect of a Change in HIV Therapy on Liver Steatosis, Inflammation, and Fibrosis

NCT00023218
View directory record Official record
Conditions
HIV Infections, Hepatitis C
Interventions
Lopinavir/Ritonavir, Efavirenz
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
13 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
3
States / cities
Honolulu, Hawaii • Tripler AMC, Hawaii • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 9, 2015 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Nutrisystem Meal Provision on Weight

NCT01252303
View directory record Official record
Conditions
Obesity
Interventions
Nutrisystem
Behavioral
Lead sponsor
University of Kentucky
Other
Eligibility
25 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 23, 2011 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional

A Study of a Values-Based Intervention to Promote Weight Loss

NCT03991676
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Values-Based Behavioral Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 70 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 24, 2019 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Osteoporosis Prevention: Changes to Exercise and Diet in Children

NCT00063050
View directory record Official record
Conditions
Osteoporosis
Interventions
Physical activity and nutrition intervention
Behavioral
Lead sponsor
San Diego State University
Other
Eligibility
10 Years to 12 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Nov 16, 2011 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Metabolic Health, Bones and Nuts During Weight Loss in Adults

NCT06949280
View directory record Official record
Conditions
Weight Loss, Bone Density, Obesity and Overweight
Interventions
Peanut Snack Experimental, Nut-free Snack
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
50 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated May 13, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Beverage Choice and Lifestyle Modification in Overweight Youth

NCT01662570
View directory record Official record
Conditions
Obesity
Interventions
Beverage Choice and Lifestyle Modification, Nutrition Education (NE)
Behavioral · Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
4 Years to 8 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 15, 2012 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of High Fruit, Vegetable, and Dairy Intake on Plasma Lipids and Blood Pressure in Healthy Individuals

NCT01404897
View directory record Official record
Conditions
Cardiovascular Disease, Dyslipidemia, Blood Pressure
Interventions
Dietary Intervention
Other
Lead sponsor
UCSF Benioff Children's Hospital Oakland
Other
Eligibility
22 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Mar 26, 2015 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

A Novel Obesity Prevention Program for High-Risk Infants in Primary Care

NCT06028113
View directory record Official record
Conditions
Obesity, Obesity, Childhood, Weight Gain, Weight Gain Trajectory
Interventions
THRIVE 2.0
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
1 Day and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 5, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional

Clinical Trial Assessing Human Placental Membrane Products and Standard of Care Versus Standard of Care in Nonhealing DFUs and VLUs

NCT06674980
View directory record Official record
Conditions
Pathologic Processes, Diabetes Mellitus, Glucose Metabolism Disorders, Metabolic Diseases, Endocrine System Disease, Diabetic Angiopathies, Vascular Diseases, Cardiovascular Diseases, Leg Ulcer, Skin Ulcer, Skin Diseases, Diabetes Complications, Diabetic Neuropathies, Foot Diseases, Diabetic Foot, Foot Ulcer, Diabetes Mellitus, Type 2, Ulcer, Foot Ulcer Unhealed
Interventions
Standard of Care - DFU, AM/Single - DFU, AM/Double - DFU, Standard of Care - VLU, AM/Single - VLU, AM/Double - VLU
Other
Lead sponsor
C5 Biomedical
Industry
Eligibility
18 Years and older
Enrollment
177 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Metairie, Louisiana
Source: ClinicalTrials.gov public record
Updated Dec 27, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional

VK2735 for Weight Management Phase 2

NCT06068946
View directory record Official record
Conditions
Weight Loss
Interventions
VK2735, Placebo
Biological
Lead sponsor
Viking Therapeutics, Inc.
Industry
Eligibility
18 Years and older
Enrollment
176 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
20
States / cities
Birmingham, Alabama • Long Beach, California • Los Angeles, California + 14 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Noom Health for Weight Management

NCT04797169
View directory record Official record
Conditions
Weight Loss, Obesity
Interventions
Noom Health, Noom Digital Health
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 60 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 11, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Leg Heating in Pregnant Women With Obesity

NCT06932250
View directory record Official record
Conditions
High-risk Pregnancy
Interventions
Leg heating
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers

NCT03843424
View directory record Official record
Conditions
Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity, Overweight, Overweight and Obesity, Overweight or Obesity, Overweight Adolescents, Weight Gain, Overnutrition, Body Weight, Body Weight Changes, Nutrition Disorders
Interventions
eSOC program, FBT program
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
6 Years to 15 Years
Enrollment
1,460 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
7
States / cities
Alton, Illinois • Baton Rouge, Louisiana • New Orleans, Louisiana + 4 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dietary Exchanges With Avocado and Mango in Pre-diabetes

NCT05353790
View directory record Official record
Conditions
Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change, Retinal Vascular
Interventions
Meals + snacks: control, Meals + snacks: Avocado mango
Other
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Industry
Eligibility
25 Years to 70 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 15, 2026 · Synced Oct 21, 2026, 5:38 AM EDT
Not listed Phase 4 Interventional

Effect of Biktarvy & Symtuza on microRNAs in HIV and Correlation With Weight Gain

NCT05463783
View directory record Official record
Conditions
HIV Infections, Obesity
Interventions
Biktarvy, Symtuza
Drug
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 14, 2023 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Randomized Study to Evaluate the Effect of an Investigational Product on Weight Loss and Body Composition

NCT01272739
View directory record Official record
Conditions
Obesity
Interventions
IHBG-10, Placebo
Dietary Supplement
Lead sponsor
Avera McKennan Hospital & University Health Center
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Sioux Falls, South Dakota
Source: ClinicalTrials.gov public record
Updated Oct 6, 2011 · Synced Oct 21, 2026, 5:38 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Commercial Program on Weight Loss and Health Outcomes

NCT03928483
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Modified WW Food program
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 75 Years
Enrollment
143 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 11, 2019 · Synced Oct 21, 2026, 5:38 AM EDT