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ClinicalTrials.gov public records Last synced Oct 28, 2026, 1:40 AM EDT

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Showing 1009–1032 of 1,516 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Recruiting Phase 2 Interventional Accepts healthy volunteers

Early Metabolic Effects of Antiretroviral Drugs in Healthy volUnteers: a Phase 2 Randomized Study

NCT05652478
View directory record Official record
Conditions
Healthy Volunteer, Weight Gain, Metabolic Effects, Integrase Strand Transfer Inhibitors
Interventions
Dolutegravir (DTG) AND Tenofovir alafenamide (TAF), Tenofovir Disoproxil Fumarate, Dolutegravir, Tenofovir alafenamide
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 55 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional

Efficacy and Safety of Frequently Modified Intensive Insulin

NCT01014832
View directory record Official record
Conditions
Diabetes
Interventions
Intensive insulin therapy
Drug
Lead sponsor
Hygieia, Inc
Industry
Eligibility
25 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Paramus, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 17, 2009 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Adapting Diet and Action for Everyone (ADAPT+)

NCT04800432
View directory record Official record
Conditions
Pediatric Obesity
Interventions
ADAPT+, EUC
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
8 Years to 12 Years
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Oct 28, 2026, 1:40 AM EDT
Recruiting Not applicable Interventional

Plant-Based Online Weight Loss Through Education and Resources Program and Study

NCT07095543
View directory record Official record
Conditions
Type 2 Diabetes, Overweight and Obese Adults
Interventions
Low-fat, vegan diet
Behavioral
Lead sponsor
Physicians Committee for Responsible Medicine
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Changing Sedentary Behavior in Youth

NCT00962247
View directory record Official record
Conditions
Obesity
Interventions
Television reduction device
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
8 Years to 12 Years
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2008
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 2 Interventional Results available

A Study to Evaluate the Change in Weight After 24 Weeks Treatment With LIK066 in Obese or Overweight Adults

NCT03100058
View directory record Official record
Conditions
Obesity, Overweight
Interventions
LIK066, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
59
States / cities
Anniston, Alabama • Jasper, Alabama • Beverly Hills, California + 52 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2020 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Exogenous Ketones on Indices of Keto-Adaptation in Obese Subjects on Weight Reducing Diets.

NCT06449287
View directory record Official record
Conditions
Ketogenic Diet, Weight Loss
Interventions
Diet, Blood Draw, Ketone/Glucose Monitoring, Body Composition, Urine Analysis, Neuropsychological Measures - ANAM
Other · Biological · Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
21 Years to 65 Years
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2024 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Continuous vs. Intermittent Caloric Restriction on Fat Los

NCT06079658
View directory record Official record
Conditions
Obesity
Interventions
Continuous Caloric Restriction versus Intermittent Caloric Restriction on Fat Loss
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Conway, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 12, 2023 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 4 Interventional

Contribution of Dolutegravir to Obesity and Cardiovascular Disease

NCT04340388
View directory record Official record
Conditions
HIV-1-infection, Antiviral Drug Adverse Reaction, Vascular Diseases, Cardiovascular Abnormalities, Abnormality of Adipose Tissue, Body Weight Changes, Body Fat Disorder, HIV-Associated Lipodystrophy Syndrome
Interventions
Dolutegravir 50 MG, Antiretroviral/Anti HIV
Drug
Lead sponsor
Augusta University
Other
Eligibility
18 Years to 100 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 3 Interventional Results available

Energy Balance & Weight Loss in Craniopharyngioma-related or Other Hypothalamic Tumors in Hypothalamic Obesity

NCT02664441
View directory record Official record
Conditions
Hypothalamic Obesity
Interventions
Exenatide, placebo
Drug
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
10 Years to 25 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
3
States / cities
Minneapolis, Minnesota • Nashville, Tennessee • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 5, 2022 · Synced Oct 28, 2026, 1:40 AM EDT
Not listed Not applicable Interventional

KIDFIT: Keeping Ideal Cardiovascular Health Family Intervention Trial

NCT03405246
View directory record Official record
Conditions
Childhood Obesity, Weight Gain, Diet Modification
Interventions
KIDFIT HEALTHY, KIDFIT SAFE
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
3 Years to 5 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 5, 2022 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 3 Interventional

Effects of Aripiprazole in Overweight Patients Treated With Olanzapine for Schizophrenia or Schizoaffective Disorder

NCT00095524
View directory record Official record
Conditions
Body Weight Change, Schizophrenia, Schizoaffective Disorder, Psychotic Disorder
Interventions
Aripiprazole
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
23
States / cities
Little Rock, Arkansas • Anaheim, California • Cerritos, California + 20 more
Source: ClinicalTrials.gov public record
Updated Nov 11, 2013 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Translating Neuroscience to Population Health

NCT03976427
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Guided Imagery
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 5, 2019 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Two Approaches to Weight Loss Follow-Up Study

NCT00143962
View directory record Official record
Conditions
Obesity
Interventions
Low Carbohydrate Diet
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The SLeeping and Intake Methods Taught to Infants and Mothers Early in Life (SLIMTIME) Project

NCT00359242
View directory record Official record
Conditions
Weight Gain, Obesity
Interventions
Infant Sleeping and Soothing, Repeated Food Exposure
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
1 Day to 12 Months
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 28, 2017 · Synced Oct 28, 2026, 1:40 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Modifying Adiposity Through Behavioral Strategies to Improve COVID-19 Rehabilitation

NCT05880108
View directory record Official record
Conditions
Post-COVID Conditions, Obesity
Interventions
12-weeks of Weight Loss, 12-weeks of Weight Stability
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Up to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
2
States / cities
Baltimore, Maryland • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 1, 2026 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 2Phase 3 Interventional

Risk-Adapted Allogeneic Stem Cell Transplantation For Mixed Donor Chimerism In Patients With Non-Malignant Diseases

NCT01019876
View directory record Official record
Conditions
Bone Marrow Failure, Osteopetrosis, Fanconi Anemia, Severe Combined Immunodeficiency
Interventions
Fludarabine, Cyclophosphamide, Busulfan, Alemtuzumab, Rabbit Anti-thymocyte Globulin, Horse Anti-thymocyte Globulin
Drug
Lead sponsor
Columbia University
Other
Eligibility
Up to 30 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Devaluing Foods to Change Eating Behavior

NCT03557710
View directory record Official record
Conditions
Overweight and Obesity, Cancer
Interventions
Devaluing energy-dense foods for cancer-control
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
18 Years to 60 Years
Enrollment
253 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Not applicable Interventional Results available

Lifestyle Modification and Metformin Use in the Treatment of HIV

NCT00399360
View directory record Official record
Conditions
HIV Infections, Metabolic Syndrome X
Interventions
Metformin, Placebo, Lifestyle Modification
Drug · Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 14, 2012 · Synced Oct 28, 2026, 1:40 AM EDT
Terminated Not applicable Interventional

Impact of a Digital Self-Management Program on A1C for Individuals With Type 2 Diabetes

NCT04892680
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Online Diabetes Self-Management Education and Support (DSMES) Program
Behavioral
Lead sponsor
Omada Health, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated May 11, 2022 · Synced Oct 28, 2026, 1:40 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Healthetech, Inc. SMART Study

NCT00194194
View directory record Official record
Conditions
Moderate Behavior Management, Intensive Behavior Management
Interventions
moderate, Resting Metablic Rate measurements
Behavioral · Device
Lead sponsor
Temple University
Other
Eligibility
21 Years and older
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 17, 2009 · Synced Oct 28, 2026, 1:40 AM EDT
Recruiting Not applicable Interventional

Randomized Evaluation of Voucher Interventions for Value and Effectiveness (REVIVE) in Philippines

NCT07640594
View directory record Official record
Conditions
Food Insecurity, Undernutrition, Diet Quality, Nutrition Knowledge
Interventions
Food Voucher + SBCC (PhP 3,000), Food Voucher + SBCC (PhP 5,000), Food Voucher + SBCC (PhP 8,000)
Behavioral
Lead sponsor
International Food Policy Research Institute
Other
Eligibility
0 Months to 99 Years
Enrollment
5,320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 28, 2026, 1:40 AM EDT
Completed No phase listed Observational

Long-term Lifestyle Change and Testosterone Replacement

NCT03256292
View directory record Official record
Conditions
Hypogonadism, Aging, Overweight and Obesity
Interventions
Testosterone replacement, lifestyle
Drug · Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
65 Years to 85 Years · Male only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2021 · Synced Oct 28, 2026, 1:40 AM EDT