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ClinicalTrials.gov public records Last synced Oct 29, 2026, 9:47 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1129–1152 of 1,516 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed Phase 1 Interventional

Effect of High Monounsaturated Fat Diet on Glycemic Control and Cardiovascular Risk Factors in Type 2 Diabetes

NCT00622960
View directory record Official record
Conditions
Overweight, Obesity, Type 2 Diabetes
Interventions
High-MUFA diet, High-CHO diet
Other
Lead sponsor
University of Cincinnati
Other
Eligibility
30 Years to 75 Years
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 25, 2008 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional

Feasibility and Preliminary Efficacy of a Reverse Diet as a Novel Weight Loss Maintenance Strategy for Weight-Reduced Adults With Overweight/Obesity

NCT03560635
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss Maintenance, Dietary Habits
Interventions
Weight Loss Maintenance (Control vs. Reverse Diet)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
21 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 19, 2022 · Synced Oct 29, 2026, 9:47 AM EDT
Completed No phase listed Observational

Optimizing GWG in Obese Pregnant Women: A Nationwide Real-World Study Using the U.S. Natality Cohort

NCT07796815
View directory record Official record
Conditions
Pregnancy in Obesity, Gestational Weight Gain
Interventions
Gestational Weight Gain
Behavioral
Lead sponsor
Shanghai First Maternal and Infant Health Hospital affiliated to Tongji University Medical School
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
1,600,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Hyattsville, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

STELLA-FTD: Examination of a Behavior Change Intervention for FTD Family Care Partners

NCT06613204
View directory record Official record
Conditions
Frontotemporal Dementia, Caregiver Burden, Primary Progressive Aphasia (PPA), Corticobasal Syndrome
Interventions
STELLA-FTD Control, STELLA-FTD Test
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
640 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 27, 2025 · Synced Oct 29, 2026, 9:47 AM EDT
Active, not recruiting Not applicable Interventional

Feasibility of the Paso Program for Patients With Metabolic Dysfunction Associated Steatotic Liver Disease

NCT06854185
View directory record Official record
Conditions
Metabolic Dysfunction Associated Steatotic Liver Disease, Overweight (BMI > 25), Metabolic Syndrome
Interventions
Paso Program
Behavioral
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 70 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Recruiting Phase 1 Interventional

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

NCT06974877
View directory record Official record
Conditions
Cryopyrin-Associated Periodic Syndromes, Amyloidosis
Interventions
124I AT-01
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 120 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Periodontal Inflammation and Epigenetics in Obese Individuals

NCT07610902
View directory record Official record
Conditions
Obesity, Periodontitis
Interventions
Non-surgical periodontal therapy will be administered
Procedure
Lead sponsor
Louisiana State University Health Sciences Center in New Orleans
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Nighttime Synchrony of Your Nutrition and Circadian Health

NCT07329283
View directory record Official record
Conditions
Sleep, Metabolism Changes, Circadian Rhythm, Lifestyle Factors, Sleep Hygiene, Sleep Hygiene, Inadequate, Sleep Deprivation, Insufficient Sleep, Circadian Misalignment, Circadian Dysregulation, Light Exposure
Interventions
Central Clock Misalignment, Peripheral Misalignment
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Targeting Weight and Shape Concern Among Women with High Body Weight

NCT05845866
View directory record Official record
Conditions
Body Image Disturbance, Overweight and Obesity, Weight Loss
Interventions
Modified Body Project, Facts about obesity, myths about weight loss, Lifestyle intervention for weight loss
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
25 Years to 70 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 30, 2025 · Synced Oct 29, 2026, 9:47 AM EDT
Completed No phase listed Observational

Exploring the Familial Reach of Adolescent Obesity Treatment

NCT05780970
View directory record Official record
Conditions
Pediatric Obesity
Interventions
No intervention
Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
8 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Henrico, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Oct 29, 2026, 9:47 AM EDT
Terminated Not applicable Interventional

Reducing Barriers to Behavior Change Among Youth With Pediatric Overweight and Obesity

NCT00863083
View directory record Official record
Conditions
Pediatric Obesity, Pediatric Overweight
Interventions
Multifamily weight management intervention
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
8 Years to 17 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jun 22, 2010 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Alternate Day Fasting for Weight Loss, Weight Maintenance and Cardio-protection

NCT00960505
View directory record Official record
Conditions
Coronary Heart Disease, Obesity, Weight Loss
Interventions
Alternate day fasting, Calorie restriction, Control diet
Other
Lead sponsor
University of Illinois Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 21, 2020 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Leisure Time Activity and Nutrition Program

NCT00656045
View directory record Official record
Conditions
Obesity, Physical Activity
Interventions
Dietary, Physical Activity, TV Watching
Behavioral
Lead sponsor
The University of Tennessee, Knoxville
Other
Eligibility
21 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Knoxville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 5, 2018 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Lifestyle Medicine Health Education and Intervention Program "Family Central E-Health"

NCT06934083
View directory record Official record
Conditions
Obesity, Life Style, Healthy, Behavioral Changes
Interventions
E-health education briefs
Behavioral
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 18, 2025 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Training and Time-restricted Feeding in Overweight and Obese Adults

NCT03823872
View directory record Official record
Conditions
Overweight and Obesity, Weight Loss
Interventions
Time restricted feeding, Normal feeding
Other
Lead sponsor
Kyle Hackney
Other
Eligibility
35 Years to 60 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fargo, North Dakota
Source: ClinicalTrials.gov public record
Updated Aug 25, 2020 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional

High Fat Diet II on Weight Loss

NCT00525850
View directory record Official record
Conditions
Obesity
Interventions
high fat diet, low saturated fat diet
Other
Lead sponsor
Christiana Care Health Services
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Newark, Delaware
Source: ClinicalTrials.gov public record
Updated Aug 2, 2011 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Comparison of Two Approaches to Weight Loss Follow-Up Study

NCT00143962
View directory record Official record
Conditions
Obesity
Interventions
Low Carbohydrate Diet
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
3
States / cities
Denver, Colorado • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2016 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Gender and Culturally Specific Approach to Reduce NAFLD in Mexican-American Men

NCT04186260
View directory record Official record
Conditions
NAFLD
Interventions
NAFLD-specific weight loss intervention, Wait-list control
Behavioral · Other
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 64 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 24, 2025 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Working for You" Workplace Obesity Intervention

NCT02934113
View directory record Official record
Conditions
Obesity, Diabetes
Interventions
iOTA, HWPP
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
1,283 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 8, 2021 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Weight Loss Study-Mechanism Underlying the Improvement of Insulin Resistance in Response to Weight Loss

NCT01780870
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Weight loss group (Full meal replacement products)
Dietary Supplement
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 50 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 7, 2017 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Program to Reduce Incontinence by Diet and Exercise

NCT00091988
View directory record Official record
Conditions
Urinary Incontinence
Interventions
Lifestyle & Behavioral Change Program, Structured Education Program
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
30 Years and older · Female only
Enrollment
338 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
4
States / cities
Birmingham, Alabama • Little Rock, Arkansas • San Francisco, California + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2020 · Synced Oct 29, 2026, 9:47 AM EDT
Active, not recruiting Phase 4 Interventional Accepts healthy volunteers

Lorcaserin in Obesity: Identification of CNS Targets Using fMRI

NCT02400359
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Lorcaserin HCl, Placebo
Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 29, 2026, 9:47 AM EDT
Completed Phase 3 Interventional

Obese Patients With or Without Comorbidities (RIO-North America)

NCT00029861
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
3,045 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Concord, California + 42 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2009 · Synced Oct 29, 2026, 9:47 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Impact of the Use of FeelWell™ Compression Garment on Individuals With a BMI ≥35

NCT03798873
View directory record Official record
Conditions
Obesity, Obesity, Abdominal, Mobility Limitation, Quality of Life, Back Pain, Pain, Chronic, Weight Change, Body, Inactivity, Exercise, Body Composition, Redundant Skin
Interventions
FeelWell™ Compression garment, Increase Mobility
Device · Behavioral
Lead sponsor
Feelwell Compression
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Shirlington, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 19, 2019 · Synced Oct 29, 2026, 9:47 AM EDT