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ClinicalTrials.gov public records Last synced Oct 30, 2026, 12:01 PM EDT

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Showing 1225–1248 of 1,516 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Completed Not applicable Interventional Results available

Metabolic Changes Induced by a Very Low Carbohydrate Diet in Youth With Type 1 Diabetes

NCT04955691
View directory record Official record
Conditions
Type1diabetes, Low Carbohydrate Diet
Interventions
low carbohydrate diet, standard carbohydrate diet
Other
Lead sponsor
Yale University
Other
Eligibility
12 Years to 21 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 16, 2025 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

fMRI and Appetite-Related Hormones Pre and Post Obesity Surgery

NCT01583725
View directory record Official record
Conditions
Obesity
Interventions
Liquid meal responses, fMRI responses to food-cues
Procedure · Behavioral
Lead sponsor
New York Obesity and Nutrition Research Center
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 27, 2024 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional

The IBEP Study: an Intervention for Lifestyle Modification in Women With Gestational Diabetes

NCT01858233
View directory record Official record
Conditions
Gestational Diabetes, Weight Gain During Pregnancy, Weight Loss After Pregnancy
Interventions
Intensive Behavioral Modification
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2015 · Synced Oct 30, 2026, 12:01 PM EDT
Recruiting Not applicable Interventional

Treating Early Type 2 Diabetes by Reducing Postprandial Glucose Excursions: A Paradigm Shift in Lifestyle Modification

NCT05766735
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Routine Care + Glycemic Excursion Minimization (RC+GEM), Routine Care (RC)
Behavioral · Other
Lead sponsor
Chiara Fabris, PhD
Other
Eligibility
30 Years to 80 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
Aurora, Colorado • Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 30, 2026, 12:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Neural Correlates of Food Choice Decision-making in Obesity and Weight Loss

NCT01218503
View directory record Official record
Conditions
Obesity, Weight Loss, Weight Control
Interventions
CHOICES - obese
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
35 Years to 55 Years · Female only
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Mom Zone: A Gestational Weight Gain Management Intervention

NCT03945266
View directory record Official record
Conditions
Overweight and Obesity, Physical Activity, Weight Change, Body, Eating Behavior
Interventions
Intervention group, Control group
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 24, 2023 · Synced Oct 30, 2026, 12:01 PM EDT
Active, not recruiting No phase listed Observational

Biological Sample Repository for Gastrointestinal Disorders

NCT05874726
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity, Primary, Gastro-Intestinal Disorder, Overweight and Obesity, Overweight, Overweight or Obesity, Diabetes Type 2, Diabetes Mellitus, Diabetes Mellitus, Type 2, Hypertension, Hyperlipidemias, Sleep Apnea, GERD, Gastroesophageal Reflux, Musculoskeletal Pain Disorder, Cancer
Interventions
Blood Collection, Urine Collection, Tissue Sample Collection
Diagnostic Test
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional

Text Messaging for Weight Loss

NCT01736111
View directory record Official record
Conditions
Obesity
Interventions
one way text, Personal feedback
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
21 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 10, 2015 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional

Feasibility and Impact of Yoga in Obesity

NCT05031221
View directory record Official record
Conditions
Yoga, Obesity, Weight Loss
Interventions
Yoga + behavioral weight loss
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Renal Considerations in the Heat Stress Recommendations (Aim2)

NCT05458843
View directory record Official record
Conditions
Hot Weather; Adverse Effect, Kidney Dysfunction, Kidney Injury, Hyperthermia, Dehydration
Interventions
Fluid replacement, No fluid replacement
Procedure
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 8, 2023 · Synced Oct 30, 2026, 12:01 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The Effects of Chia on Overweight/Obese Women

NCT03233906
View directory record Official record
Conditions
Obesity, Eating Behavior, Mood, Glucose, Dietary Modification
Interventions
Chia Seeds- Salvia Hispanica
Dietary Supplement
Lead sponsor
California State Polytechnic University, Pomona
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated May 11, 2018 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

HDL Lipidomic, Proteomic and Functional Changes in Women After Eating Eggs

NCT02445638
View directory record Official record
Conditions
Overweight, Obesity
Interventions
Whole egg, Yolk-free egg
Other
Lead sponsor
University of California, Davis
Other
Eligibility
45 Years to 70 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Davis, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2019 · Synced Oct 30, 2026, 12:01 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

BAriatric Surgery Induced Chromosomal Change

NCT05903521
View directory record Official record
Conditions
Obesity, Morbid
Interventions
Not listed
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Weston, Florida
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 30, 2026, 12:01 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Observing Performance of Haptic Vibrotactile Trigger Technology by Measuring Changes in Resting Metabolic Rate: Assessment and Analysis

NCT07781384
View directory record Official record
Conditions
Resting Metabolic Rate, Energy Metabolism, Haptic Technology, Vibrotactile Stimulation
Interventions
IGNITE Patch (Active), Inactive patch
Device
Lead sponsor
SuperPatch Limited LLC
Industry
Eligibility
18 Years to 85 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Tyrone, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 24, 2026 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Neurocognitive Benefits of a Weight Management Program

NCT04202133
View directory record Official record
Conditions
Overweight and Obesity
Interventions
WW (formerly Weight Watchers), Waitlist
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
61 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Acute Effects of Fitness Drink Formulas on Energy Expenditure and Fat Metabolism

NCT04455009
View directory record Official record
Conditions
Caffeine, Diet, Healthy, Fat Burn, Cognitive Change, Fatigue
Interventions
Fitness Drink Formula
Dietary Supplement
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 35 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 2, 2020 · Synced Oct 30, 2026, 12:01 PM EDT
Terminated Not applicable Interventional

Pilot Study of Dietary Modification of Appetite Set Point in Obesity

NCT00726271
View directory record Official record
Conditions
Obesity
Interventions
light olive oil, fish oil capsules, flax seed oil capsules
Dietary Supplement
Lead sponsor
State University of New York - Upstate Medical University
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Oct 30, 2026, 12:01 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Good Intentions Study

NCT03498781
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Exercise-only, Control
Other
Lead sponsor
USDA Grand Forks Human Nutrition Research Center
Federal
Eligibility
18 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Grand Forks, North Dakota
Source: ClinicalTrials.gov public record
Updated Feb 2, 2022 · Synced Oct 30, 2026, 12:01 PM EDT
Recruiting Not applicable Interventional

Evaluating the Efficacy of Perinatal Membrane Allografts in Addition to the Standard of Care for the Treatment of Non-healing Diabetic Foot Ulcers.

NCT06437028
View directory record Official record
Conditions
Diabetic Foot Ulcer
Interventions
Dual-layer perinatal tissue allograft, Three-layer fenestrated perinatal tissue allograft, Standard of care
Other
Lead sponsor
Samaritan Biologics
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Monroe, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Incentivizing Lifestyle Modification to Reduce Disease Burden

NCT02945332
View directory record Official record
Conditions
Obesity, Diabetes Mellitus
Interventions
Required supervised walking, Non-required supervised walking, Fitbit Flex
Behavioral · Device
Lead sponsor
Texas Tech University
Other
Eligibility
18 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Oct 30, 2026, 12:01 PM EDT
Terminated Not applicable Interventional Results available

Octreotide Therapy in Children and Young Adults With Prader-Willi Syndrome (PWS)

NCT00399893
View directory record Official record
Conditions
Prader-Willi Syndrome
Interventions
Octreotide, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
5 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Oct 30, 2026, 12:01 PM EDT
Recruiting Not applicable Interventional

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

NCT06138821
View directory record Official record
Conditions
Obesity, Liver Diseases, Liver Fibrosis, Liver Fat, Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Dysfunction-Associated Steatohepatitis, MASLD, MASH, Weight Loss, Insulin Resistance, Insulin Sensitivity, Insulin Sensitivity/Resistance, Metabolic Disease, Diabetes, Diabetes Mellitus, Type 2, NASH With Fibrosis, Non-Alcoholic Fatty Liver Disease, Non Alcoholic Fatty Liver, Non-alcoholic Steatohepatitis
Interventions
ESG + lifestyle modification, Lifestyle modification
Device · Behavioral
Lead sponsor
Pichamol Jirapinyo, MD, MPH
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 30, 2026, 12:01 PM EDT
Recruiting Phase 1 Interventional

Repeat PET/CT Imaging in People With CAPS and Anakinra-Induced Amyloidosis Using an Amyloid-Reactive Peptide to Measure Changes in Organ-Specific Amyloid Load

NCT06974877
View directory record Official record
Conditions
Cryopyrin-Associated Periodic Syndromes, Amyloidosis
Interventions
124I AT-01
Drug
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 120 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Oct 30, 2026, 12:01 PM EDT
Completed Not applicable Interventional

A Remote Delivered Lifestyle Therapeutics Program

NCT04201028
View directory record Official record
Conditions
Body Weight Changes, Weight Loss, Healthy Diet, Obesity
Interventions
Video Conferencing Health Coaching with devices, Video Conferencing Health Coaching with no devices
Behavioral
Lead sponsor
Coastal Carolina University
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Bradenton, Florida
Source: ClinicalTrials.gov public record
Updated Oct 6, 2022 · Synced Oct 30, 2026, 12:01 PM EDT