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ClinicalTrials.gov public records Last synced Oct 21, 2026, 9:06 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 1,514 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Changes Clear all
Recruiting Not applicable Interventional

Weight Management Intervention in College: A Pilot

NCT06994923
View directory record Official record
Conditions
Obesity and Overweight
Interventions
BWLI-College, Control
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 29 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Oct 1, 2025 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exploring Optimal Treatment Components for Contactless Online Group-based Behavioral Weight Loss Program

NCT04514900
View directory record Official record
Conditions
Obesity
Interventions
Video Chat +Personalized Feedback, Video Chat + Basic Feedback, Discussion Board for Social Support +Basic Feedback, Discussion Board for Social Support+Personalized Feedback
Behavioral
Lead sponsor
University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 30, 2021 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating a Remotely Delivered Plant-Based Behavioral Weight Loss Treatment

NCT04892030
View directory record Official record
Conditions
Obesity, Overweight
Interventions
Whole Food Plant-Based Behavioral Weight Loss Treatment
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 1, 2021 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

The GEM (Goals for Eating and Moving) Study

NCT03006328
View directory record Official record
Conditions
Weight Gain, Obesity
Interventions
GEM, Enhanced Usual Care
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 69 Years
Enrollment
489 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 27, 2023 · Synced Oct 21, 2026, 9:06 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

The Path to Optimal Black Maternal Heart Health: Comparing Two CVD Risk Reduction Interventions (Change of HEART)

NCT05499507
View directory record Official record
Conditions
Pregnancy Related, Hypertension, Obesity, Racism
Interventions
COH+
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years and older · Female only
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2029
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Diabetes Risk Education and Communication Trial

NCT03283657
View directory record Official record
Conditions
PreDiabetes, Diabetes Mellitus, Diabetes Mellitus, Type 2, Body Weight, Body Weight Changes
Interventions
DiRECT, Usual care (UC)
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 7, 2022 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Weight Loss for Prediabetes Using Episodic Future Thinking

NCT03670602
View directory record Official record
Conditions
PreDiabetes
Interventions
Episodic Future Thinking, Daily Check in
Behavioral
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years to 74 Years
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
2
States / cities
Buffalo, New York • Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 9, 2022 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Phase 3 Interventional

Obese Patients With or Without Comorbidities (RIO-North America)

NCT00029861
View directory record Official record
Conditions
Obesity, Weight Loss
Interventions
Rimonabant (SR141716)
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
3,045 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
47
States / cities
Birmingham, Alabama • Phoenix, Arizona • Concord, California + 42 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2009 · Synced Oct 21, 2026, 9:06 AM EDT
Not listed Not applicable Interventional

EMPOWER Weight Management

NCT04635722
View directory record Official record
Conditions
Obesity, Overweight, Weight Loss, Diet Habit
Interventions
Weight Management Intervention
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Oct 21, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional

Weight Loss and ExeRcise for Post-stroke Veterans

NCT06322030
View directory record Official record
Conditions
Stroke
Interventions
FOCUS-15 Lifestyle Management Program, Exercise Training
Dietary Supplement · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years to 80 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 15, 2026 · Synced Oct 21, 2026, 9:06 AM EDT
Completed No phase listed Observational

Using Exhaled Air to Determine Changes in Nutritional Status of Patients on Intravenous Nutrition

NCT02843256
View directory record Official record
Conditions
Obesity, Malnourished, Fasting
Interventions
Isomark Canary
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 28, 2017 · Synced Oct 21, 2026, 9:06 AM EDT
Completed No phase listed Observational

Redistribution of Fat and Metabolic Change in HIV Infection: Protocol 2 (FRAM Fat 2)

NCT00244803
View directory record Official record
Conditions
Human Immunodeficiency Virus
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 31, 2016 · Synced Oct 21, 2026, 9:06 AM EDT
Completed No phase listed Observational

Exploring How to Adapt an Evidence-Based Mindful Self-Compassion Program for Young Adults With Li-Fraumeni Syndrome

NCT07032922
View directory record Official record
Conditions
Li-Fraumeni Syndrome
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 29 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Metabolism and Thyroid Hormone Changes During Exposure to Cold Temperatures

NCT00521729
View directory record Official record
Conditions
Obesity
Interventions
Exposure to Cold Temperature
Procedure
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
18 Years to 60 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2019 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Childhood Obesity Treatment: A Maintenance Approach

NCT00301197
View directory record Official record
Conditions
Obesity
Interventions
Behavioral Skills Maintenance, Social Facilitation Maintenance
Behavioral
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
7 Years to 12 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 10, 2006 · Synced Oct 21, 2026, 9:06 AM EDT
Terminated Phase 4 Interventional Accepts healthy volunteers Results available

Study to Evaluate the Efficacy and Safety of Belviq XR® in Conjunction With Lifestyle Modification for Weight Loss in Obese Adolescents, Age 12 to 17 Years

NCT03338296
View directory record Official record
Conditions
Obesity
Interventions
lorcaserin hydrochloride XR, Placebo
Drug
Lead sponsor
Eisai Inc.
Industry
Eligibility
12 Years to 17 Years
Enrollment
278 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
16
States / cities
Phoenix, Arizona • Bell Gardens, California • Long Beach, California + 13 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Results available

Comparison of Two Programs for Weight Loss and Impact on Metabolic Syndrome

NCT02023515
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Emotional brain training, Behavioral weight loss
Behavioral
Lead sponsor
Kelly Webber
Other
Eligibility
25 Years to 55 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 27, 2017 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Changes in Food Reinforcement During Obesity Treatment

NCT00200291
View directory record Official record
Conditions
Obesity
Interventions
hypocaloric, low-fat diet
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
21 Years to 70 Years · Female only
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 20, 2012 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Testing the Effect of Multiple Weight Management Modalities for Chronic Disease Risk Reduction in a Clinical Setting

NCT03998878
View directory record Official record
Conditions
Obesity
Interventions
Low-Carbohydrate Diet, Intermittent Energy Restriction, Hunger Training
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Dec 17, 2021 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Weight Gain Prevention

NCT00606840
View directory record Official record
Conditions
Weight Gain
Interventions
large changes in eating and activity, small changes in eating and activity
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Apr 13, 2012 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Lean Living Study

NCT02501889
View directory record Official record
Conditions
Overweight and Obesity
Interventions
Walnut-rich weight loss diet, Standard weight loss diet
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
21 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
La Jolla, California
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

mHealth Intervention for Older Adults

NCT03398590
View directory record Official record
Conditions
Type2 Diabetes, Obesity
Interventions
self-regulation theory-based mHealth behavior intervention
Behavioral
Lead sponsor
Boston College
Other
Eligibility
65 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 22, 2018 · Synced Oct 21, 2026, 9:06 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

How Animal and Plant Protein Shakes Change the Body's Nutrient and Health Responses

NCT07121010
View directory record Official record
Conditions
Cardiometabolic Health
Interventions
Animal-Based Protein Smoothie, Plant-Based Protein Smoothie, Plant-Based Protein Smoothie with Leucine
Dietary Supplement
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 6, 2026 · Synced Oct 21, 2026, 9:06 AM EDT
Completed Not applicable Interventional

Targeted Lifestyle Change Group Prenatal Care

NCT04090307
View directory record Official record
Conditions
Pregnancy, Gestational Diabetes
Interventions
TLC Group Prenatal Care
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
13 Years and older · Female only
Enrollment
305 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
St Louis, Missouri • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 18, 2026 · Synced Oct 21, 2026, 9:06 AM EDT