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ClinicalTrials.gov public records Last synced Oct 14, 2026, 9:59 PM EDT

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Showing 457–480 of 8,436 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism Disorder, Glucose Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Pharmacokinetic Drug Interaction Study of Dapagliflozin and Valsartan or Simvastatin in Healthy Subjects

NCT00839683
View directory record Official record
Conditions
Type 2 Diabetes Mellitus
Interventions
simvastatin, Dapagliflozin, valsartan
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
18 Years to 45 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Neptune City, New Jersey
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 14, 2026, 9:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

A Sensory Strategy to Cut Sugary Beverages in African/American and Latine Adolescents

NCT07223151
View directory record Official record
Conditions
Obesity, Adolescent, Dietary Sugars, Taste Perception, Insulin Resistance, Feeding Behavior
Interventions
Unsweetened Sparkling Water Replacement, Progressively Reduced Sugar Beverage Replacement, Plain Water Replacement
Behavioral
Lead sponsor
Nana Gletsu Miller
Other
Eligibility
12 Years to 18 Years
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
3
States / cities
Bloomington, Indiana • Indianapolis, Indiana • West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Coffee Roasting on Blood Sugar Levels in Healthy Humans

NCT05119153
View directory record Official record
Conditions
Hyperglycemia
Interventions
Placebo Comparator, Light Roasted Coffee, Medium Roasted Coffee, Dark Roasted Coffee
Dietary Supplement
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 65 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 12, 2021 · Synced Oct 14, 2026, 9:59 PM EDT
Recruiting Phase 4 Interventional

Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients

NCT06140537
View directory record Official record
Conditions
Kidney Transplant; Complications, Vascular Diseases, Diabetes
Interventions
Dapagliflozin 10mg Tab, Placebo
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 29, 2025 · Synced Oct 14, 2026, 9:59 PM EDT
Not yet recruiting No phase listed Observational

Evaluation of the Clinical Spectrum of Diabetes and Obesity in Youth and Adults

NCT07388537
View directory record Official record
Conditions
Obesity, Diabetes, Metabolic Disorders
Interventions
Not listed
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
8 Years to 65 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2055
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 3 Interventional Results available

A Study In Patients With Type 2 Diabetes Mellitus

NCT00256867
View directory record Official record
Conditions
Diabetes Mellitus, Type 2
Interventions
GSK523338
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 75 Years
Enrollment
369 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
43
States / cities
Tucson, Arizona • Fresno, California • Wheat Ridge, Colorado + 38 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2018 · Synced Oct 14, 2026, 9:59 PM EDT
Terminated Not applicable Interventional Results available

Diabetic Foot Infection Antibiotic Study

NCT01539811
View directory record Official record
Conditions
Diabetic Foot Infections
Interventions
Surgical incision and drainage of diabetic foot infection, Short course antibiotics, Long course antibiotics
Procedure · Drug
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 14, 2026, 9:59 PM EDT
Recruiting Phase 3 Interventional

Comparative Effectiveness of Two Initial Combination Therapies in Patients With Recent Onset Diabetes

NCT06246799
View directory record Official record
Conditions
Type 2 Diabetes (Adult Onset)
Interventions
Tirzepatide, Pioglitazone, Sitagliptin, Metformin HCI XR
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 75 Years
Enrollment
256 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 3 Interventional

A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes

NCT01455857
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
ITCA 650, ITCA placebo
Drug · Other
Lead sponsor
Intarcia Therapeutics
Industry
Eligibility
18 Years to 80 Years
Enrollment
460 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
121
States / cities
Birmingham, Alabama • Gulf Shores, Alabama • Huntsville, Alabama + 102 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Not applicable Interventional Results available

Mi Puente: My Bridge to Better Cardiometabolic Health and Well-Being

NCT02723019
View directory record Official record
Conditions
Type 2 Diabetes Mellitus, Cardiometabolic Conditions, Behavioral Health Concerns
Interventions
Volunteer Peer Mentor+Behavioral Health Nurse
Behavioral
Lead sponsor
Scripps Whittier Diabetes Institute
Other
Eligibility
18 Years and older
Enrollment
536 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Chula Vista, California
Source: ClinicalTrials.gov public record
Updated Feb 28, 2023 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 3 Interventional Results available

An Intervention Trial for Cardiac Neuropathy in Type 1 Diabetes

NCT00116207
View directory record Official record
Conditions
Diabetic Autonomic Neuropathy
Interventions
ORAL ANTIOXIDANT
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 65 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 29, 2016 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Blood Glucose Meter Systems

NCT01714232
View directory record Official record
Conditions
Diabetes
Interventions
Contour® PLUS BGMS, OneTouch® SelectSimple™ BGMS, Accu-Chek® Performa BGMS, Accu-Chek® Active BGMS, Freestyle Freedom® BGMS
Device
Lead sponsor
Ascensia Diabetes Care
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Mishawaka, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 29, 2016 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Not applicable Interventional

Physical Activity and Glycemic Control in Adolescents

NCT02674828
View directory record Official record
Conditions
Type 1 Diabetes
Interventions
Reinforcement for meeting targeted physical activity goals, Standard of Care
Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
13 Years to 24 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 7, 2020 · Synced Oct 14, 2026, 9:59 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

NCT06605898
View directory record Official record
Conditions
Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
Interventions
MIND Diet, Control Diet
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
45 Years to 64 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 1 Interventional Results available

Characteristics of Glargine in Type 2 Diabetics

NCT00574912
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Placebo, Insulin Glargine 0.5 u/kg body wt SC, Insulin Glargine 1.0 u/kg body wt SC, Insulin Glargine 1.5 u/kg body wt SC, Insulin Glargine 2.0 u/kg body wt SC
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 17, 2017 · Synced Oct 14, 2026, 9:59 PM EDT
Terminated Phase 2 Interventional Results available

A Study to Assess Efficacy/Safety of Ladarixin in Type 1 Diabetes Patients With Preserved ß-cell Function at Baseline.

NCT04899271
View directory record Official record
Conditions
New-onset Type 1 Diabetes
Interventions
Ladarixin, Placebo
Drug · Other
Lead sponsor
Dompé Farmaceutici S.p.A
Industry
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
2
States / cities
Aurora, Colorado • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Not applicable Interventional Results available

The National Diabetes Prevention Program in Rural Communities

NCT05387434
View directory record Official record
Conditions
PreDiabetes, Weight Loss, Lifestyle Risk Reduction
Interventions
Diabetes Prevention Program-Remote (DPP-R), Diabetes Prevention Program-Facebook (DPP-FB)
Behavioral
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 8, 2023 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluating the Effects of Foot Orthotics on Plantar Pressures in the Diabetic Population

NCT00240175
View directory record Official record
Conditions
Diabetes
Interventions
No Intervention
Other
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 66 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2011
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 1, 2012 · Synced Oct 14, 2026, 9:59 PM EDT
Completed Phase 2 Interventional Results available

Metformin in Kidney Disease

NCT02252081
View directory record Official record
Conditions
Chronic Kidney Disease, Cardiovascular Disease, Metabolic Syndrome
Interventions
metformin, Placebo
Drug
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 4, 2021 · Synced Oct 14, 2026, 9:59 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Peru Longitudinal Study

NCT03742219
View directory record Official record
Conditions
Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias, Overweight and Obesity
Interventions
Lifestyle Modification
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
12 Years and older
Enrollment
861 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 15, 2021 · Synced Oct 14, 2026, 9:59 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Glycemic Impact of Myo-inositol in Pregnancy

NCT02149992
View directory record Official record
Conditions
Gestational Diabetes Mellitus as Antepartum Condition
Interventions
myo-inositol, Continuous glucose monitoring surveillance, Glucose monitoring
Dietary Supplement · Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
13 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 18, 2016 · Synced Oct 14, 2026, 9:59 PM EDT
Withdrawn Phase 3 Interventional

A Study to Evaluate ITCA 650 Compared to Sitagliptin for the Treatment of Type 2 Diabetes

NCT01455909
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
ITCA 650 60 mcg/day, sitagliptin
Drug
Lead sponsor
Intarcia Therapeutics
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Hayward, California
Source: ClinicalTrials.gov public record
Updated Dec 25, 2012 · Synced Oct 14, 2026, 9:59 PM EDT
Not listed Early Phase 1 Interventional Accepts healthy volunteers

Role of Gastrointestinal Microbes on Digestion of Resistant Starch and Tryptophan Availability to Humans

NCT02974699
View directory record Official record
Conditions
Type II Diabetes
Interventions
Potato Starch (Bob's Red Mill), Pregelatinized Starch (Resource ThickenUp)
Dietary Supplement
Lead sponsor
Wayne State University
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Oct 14, 2026, 9:59 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Diabetic Ketoacidosis and Its Impact on the Brain

NCT01753934
View directory record Official record
Conditions
Diabetes Mellitus
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
4 Years to 16 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 14, 2026, 9:59 PM EDT