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ClinicalTrials.gov public records Last synced Oct 30, 2026, 1:33 AM EDT

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Showing 1585–1608 of 6,298 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Metabolism and Nutrition Disorders Clear all
Completed Early Phase 1 Interventional

Metformin Hydrochloride vs. Placebo in Overweight or Obese Patients at Elevated Risk for Breast Cancer

NCT01793948
View directory record Official record
Conditions
Breast Cancer, Obesity
Interventions
metformin hydrochloride, placebo, laboratory biomarker analysis
Drug · Other
Lead sponsor
Anna Maria Storniolo
Other
Eligibility
18 Years to 75 Years · Female only
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 30, 2018 · Synced Oct 30, 2026, 1:33 AM EDT
Terminated Phase 3 Interventional Results available

Effect of Vitamin D Supplement on Inflammation Markers in High-Risk Cardiovascular Patients With Chronic Kidney Disease

NCT01012414
View directory record Official record
Conditions
Coronary Artery Disease, Chronic Kidney Disease, Hypovitaminosis D, Secondary Hyperparathyroidism
Interventions
paricalcitol, placebo
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 20, 2014 · Synced Oct 30, 2026, 1:33 AM EDT
Recruiting Phase 2 Interventional

A Phase 2A Clinical Trial to Assess the Safety and Tolerability of ERX1000 in Men and Women for the Treatment of Obesity.

NCT07570758
View directory record Official record
Conditions
Obesity & Overweight
Interventions
ERX1000, Placebo
Drug · Other
Lead sponsor
ERX Pharmaceuticals
Industry
Eligibility
18 Years to 60 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
3
States / cities
Louisville, Kentucky • Monroe, North Carolina • North Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Eating Mindfully to Prevent Weight Regain

NCT04847843
View directory record Official record
Conditions
Weight Loss, Weight Gain, Eating Behavior, Obesity, Bariatric Surgery Candidate
Interventions
Mindfulness Orientated Recovery Enhancement, Control Intervention
Behavioral
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional

Morning Versus Evening Exercise for Adults With Overweight and Obesity

NCT04262115
View directory record Official record
Conditions
Overweight and Obesity
Interventions
AM-EX, PM-EX
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 56 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 12, 2021 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Soy, Bone and Health in College Females

NCT00244478
View directory record Official record
Conditions
Osteoporosis, Obesity
Interventions
Soy Protein Dietary Supplement, Placebo
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 19 Years · Female only
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 25, 2015 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 1 Interventional

ALT-801 in Diabetic and Non-Diabetic Overweight and Obese Subjects With Non-alcoholic Fatty Liver Disease (NAFLD)

NCT05006885
View directory record Official record
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
ALT-801, Placebo
Drug · Other
Lead sponsor
Altimmune, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
15
States / cities
Scottsdale, Arizona • Tucson, Arizona • Montclair, California + 9 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2023 · Synced Oct 30, 2026, 1:33 AM EDT
Recruiting Not applicable Interventional

FEAST Perinatal Support Program Intervention

NCT06715787
View directory record Official record
Conditions
Diet, Healthy, Obesity, Cardiometabolic Syndrome
Interventions
FEAST Perinatal Support Program
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 3 Interventional Results available

Cognitive-Behavioral and Pharmacologic (LDX) Treatment of Binge-Eating Disorder and Obesity: Acute Treatment

NCT03924193
View directory record Official record
Conditions
Binge-Eating Disorder, Obesity
Interventions
Lisdexamfetamine Dimesylate, Cognitive-Behavioral Therapy, Combination LDX and Cognitive-Behavioral Therapy
Drug · Behavioral · Other
Lead sponsor
Yale University
Other
Eligibility
18 Years to 64 Years
Enrollment
141 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 17, 2024 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy Study of S-309309 in Obese Adults

NCT05925114
View directory record Official record
Conditions
Obesity
Interventions
S-309309, Placebo
Drug
Lead sponsor
Shionogi
Industry
Eligibility
18 Years and older
Enrollment
365 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
49
States / cities
Birmingham, Alabama • Phoenix, Arizona • Los Angeles, California + 40 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2025 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 3 Interventional

8-week Pilot Study of Relaxation for Weight Loss in Adults With Chronic Kidney Disease

NCT00944138
View directory record Official record
Conditions
Obesity
Interventions
Relaxation methods
Behavioral
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years to 88 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 28, 2010 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional

FirstWIND: Weight Loss Interventions After Delivery

NCT00377026
View directory record Official record
Conditions
Overweight, Obesity
Interventions
lifestyle intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 19, 2009 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 1 Interventional

Effects of Treating Vitamin D Deficiency in Poorly Controlled Type 2 Diabetes

NCT01855321
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Vitamin D, Placebo
Drug
Lead sponsor
University of Florida
Other
Eligibility
30 Years to 65 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 26, 2015 · Synced Oct 30, 2026, 1:33 AM EDT
Withdrawn No phase listed Observational

GLP-1 RA on Liver OMICS in MASLD

NCT06982378
View directory record Official record
Conditions
NAFLD, Diabetes, Obesity
Interventions
GLP-1 receptor agonist
Drug
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 30, 2026, 1:33 AM EDT
Completed No phase listed Observational Results available

Diabetes and Gastric By- Pass

NCT01153516
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 27, 2019 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional

Using Interventional Informatics to Address Social Determinants of Health During Clinical Care Visits to Promote Behavior Change and PREVENT Cardiovascular Disease

NCT06121193
View directory record Official record
Conditions
Cardiovascular Diseases, Obesity
Interventions
PREVENT tool, Wait-list Control
Behavioral
Lead sponsor
Washington University School of Medicine
Other
Eligibility
12 Years to 17 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2023 · Synced Oct 30, 2026, 1:33 AM EDT
Active, not recruiting Phase 2 Interventional

High-dose Vitamin D Supplements in Older Adults

NCT03613116
View directory record Official record
Conditions
Vitamin D Deficiency, Cognitive Decline
Interventions
Vitamin D3
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years to 90 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of L-citrulline Supplementation on Vascular Function in Metabolic Syndrome

NCT06025357
View directory record Official record
Conditions
Metabolic Syndrome, Menopause
Interventions
L-Citrulline supplementation, Placebo
Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
45 Years to 79 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated May 15, 2025 · Synced Oct 30, 2026, 1:33 AM EDT
Terminated Not applicable Interventional Results available

Surgical Application of Vac Dressings In Obese Patients to Reduce Wound Complications

NCT02461433
View directory record Official record
Conditions
Wound Infection, Surgical, Obesity, Postoperative Complications
Interventions
Prevena, Standard Dressing
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Feb 26, 2019 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

Healthy Lifestyles for Mentally Ill People Who Have Experienced Weight Gain From Their Antipsychotic Medications

NCT00344500
View directory record Official record
Conditions
Diabetes, Obesity, Weight Gain
Interventions
Behavioral Weight Loss Program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 70 Years
Enrollment
122 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2009
U.S. locations
1
States / cities
West Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2016 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance and Aerobic Exercise With Nutritional Supplementation in Men and Women

NCT00812409
View directory record Official record
Conditions
Obesity
Interventions
Whey protein supplementation with exercise, Non protein supplementation with exercise (control)
Dietary Supplement · Other
Lead sponsor
Purdue University
Other
Eligibility
35 Years to 65 Years
Enrollment
580 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jan 17, 2013 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional

The Hypothalamic-Pituitary-Adrenal (HPA) Axis as an Effector System in Weight Regulation

NCT00688987
View directory record Official record
Conditions
Obesity, Addison's Disease
Interventions
Hydrocortisone, Isocaloric Diet
Drug · Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2004
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jun 5, 2008 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Not applicable Interventional Results available

Time Restricted Eating for Metabolic and Psychological Optimization

NCT05997316
View directory record Official record
Conditions
Mild Cognitive Impairment, Obesity
Interventions
Time restricted eating
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 24, 2026 · Synced Oct 30, 2026, 1:33 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Metabolic Effect of Metformin in Obese Insulin Resistant Adolescents With Normal Glucose Tolerance

NCT00667498
View directory record Official record
Conditions
Pediatric Obesity, Insulin Resistance, Hyperinsulinemia
Interventions
Metformin, Placebo
Drug
Lead sponsor
Yale University
Other
Eligibility
13 Years to 17 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 18, 2009 · Synced Oct 30, 2026, 1:33 AM EDT