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Showing 1–24 of 61 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Metabolome Clear all
Completed No phase listed Observational

Ocrelizumab Effects on the Metabolome in MS

NCT03873389
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Ocrelizumab
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 75 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 11, 2023 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Epigenetic Effects of a Single Bout of Exercise on Cardiovascular Risk Factors and the Metabolome

NCT05034380
View directory record Official record
Conditions
Obesity, Type 2 Diabetes, Cardiovascular Diseases, Acute Exercise
Interventions
Acute exercise
Behavioral
Lead sponsor
East Carolina University
Other
Eligibility
18 Years to 30 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 4, 2021 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational

Environmental Health Effects on Your Physiology

NCT03986814
View directory record Official record
Conditions
Obesity
Interventions
Not listed
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
18 Years to 25 Years
Enrollment
92 participants
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 3, 2026, 5:07 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Developmental Impacts of Microplastics Exposure in Early Life

NCT06107933
View directory record Official record
Conditions
Infant Development, Breast Feeding, Environmental Exposure
Interventions
Observational only
Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 3, 2026, 5:07 AM EDT
Active, not recruiting Early Phase 1 Interventional

The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease

NCT06113003
View directory record Official record
Conditions
HIV, Non-Alcoholic Fatty Liver Disease, Metabolic-Associated Steatotic Liver Disease
Interventions
Prebiotic, Probiotic
Dietary Supplement
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impacts of Fruit on the Gut Health and Human Health

NCT05063929
View directory record Official record
Conditions
Cardiometabolic Health, Healthy Aging, Cognition
Interventions
Fruit (2 cup eq), Fruit restriction (1/2 cup eq)
Other
Lead sponsor
San Diego State University
Other
Eligibility
30 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

American Cranberries to Prevent UTIs in Susceptible Women

NCT04626362
View directory record Official record
Conditions
Healthy
Interventions
Cranberry juice
Other
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pre-analytical Sample Handling Conditions and Their Effects on the Human Urine Metabolome

NCT03063502
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
20 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 2, 2017 · Synced Sep 3, 2026, 5:07 AM EDT
Terminated No phase listed Observational

Breath Metabolomics in the Laboring Parturient

NCT04564196
View directory record Official record
Conditions
Labor Onset and Length Abnormalities
Interventions
Breath Sample
Procedure
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older · Female only
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 7, 2023 · Synced Sep 3, 2026, 5:07 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Successful Fiber Food Introduction in Short Bowel Syndrome

NCT06240065
View directory record Official record
Conditions
Short Gut Syndrome
Interventions
Green bean puree
Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
4 Months to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
2
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional

Response of the Gut Microbiome and Circulating Metabolome to Diet in Children: Ancillary Study to KIDFIT (NCT03405246)

NCT03612479
View directory record Official record
Conditions
Gastrointestinal Microbiome, Metabolome, Pediatric Obesity, Dietary Approaches to Stop Hypertension
Interventions
KIDFIT Healthy, KIDFIT Safe
Behavioral
Lead sponsor
Northwestern University
Other
Eligibility
3 Years to 5 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 28, 2022 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Discrimination and the Brain-Gut-Microbiome (BGM) Axis

NCT05120908
View directory record Official record
Conditions
Discrimination, Racial, Social Isolation, Stress
Interventions
Not listed
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
266 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jan 9, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Pre-analytical Sample Handling Conditions and Their Effects on the Human Serum Metabolome

NCT02697500
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
USDA Beltsville Human Nutrition Research Center
Federal
Eligibility
20 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Beltsville, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Metabolome and Microbiomic in Fecal Samples

NCT00938028
View directory record Official record
Conditions
Infant
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
12 Months to 20 Months
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2009 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational

Integrating Magnetic Imaging With Rich Phenotypes

NCT06615531
View directory record Official record
Conditions
Intensive Meditation in Novice and Experienced Meditators
Interventions
Advanced multi-component meditation practice
Behavioral
Lead sponsor
Tobias Moeller-Bertram
Industry
Eligibility
21 Years and older
Enrollment
21 participants
Timeline
2022 – 2023
U.S. locations
1
States / cities
Palm Desert, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2024 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Flavonoid-rich Supplement Influence on the Human Metabolome

NCT03004742
View directory record Official record
Conditions
Inflammation
Interventions
Flavonoid, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 1, 2017 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stool Microbiome, Pathogens, and Infectious Agents Among Olympic and Elite Athletes

NCT02818413
View directory record Official record
Conditions
Athletic Performance
Interventions
Biospecimen collection and questionnaires
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 28, 2017 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Concord Grape Polyphenol-soy Protein Isolate Complex (GP-SPI) on Gut Microbiota

NCT04018066
View directory record Official record
Conditions
Mechanisms, Defense
Interventions
GP-SPI
Dietary Supplement
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 35 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
New Brunswick, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 17, 2026 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fiber Blends and Gut Microbiota (FB)

NCT04101344
View directory record Official record
Conditions
Gut Microbiome
Interventions
Two fiber-blend snack and four fiber-blend snack
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 26, 2024 · Synced Sep 3, 2026, 5:07 AM EDT
Recruiting No phase listed Observational

InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort

NCT05929976
View directory record Official record
Conditions
Acute Lymphoblastic Leukemia, Nutrition Aspect of Cancer, Microtia, Genetic Predisposition
Interventions
No intervention
Other
Lead sponsor
Columbia University
Other
Eligibility
3 Years to 18 Years
Enrollment
4,900 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Pilot Feasibility of Rice Bran Supplementation in Children

NCT02557373
View directory record Official record
Conditions
Dietary Rice Bran Supplementation
Interventions
Vitamin A, Rice Bran + Vitamin A
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
4 Months to 10 Months
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Sep 3, 2026, 5:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Type 1 Diabetes Mellitus and Increased Weight on Gut Microbiome and Urine Metabolome Profiles in Children

NCT02938806
View directory record Official record
Conditions
Obesity, Overweight, Type 1 Diabetes Mellitus
Interventions
No intervention
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
7 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 30, 2022 · Synced Sep 3, 2026, 5:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dose-dependent Identification of Unique Biomarkers

NCT05600348
View directory record Official record
Conditions
Healthy
Interventions
Pork Consumption
Dietary Supplement
Lead sponsor
San Diego State University
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Jan 7, 2025 · Synced Sep 3, 2026, 5:07 AM EDT
Recruiting Phase 1 Interventional

Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan®

NCT06298409
View directory record Official record
Conditions
Small Intestinal Bacterial Overgrowth
Interventions
CapScan collection capsule
Device
Lead sponsor
Envivo Bio Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2025 · Synced Sep 3, 2026, 5:07 AM EDT