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ClinicalTrials.gov public records Last synced Nov 14, 2026, 11:47 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 1–24 of 93 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Microbiome, Human Clear all

Conditions: Stress Response, Mental Stress, Multitasking Behavior and Multitasking Ability, Physiological Stress, Cognitive Symptoms, Motor Activity
Interventions: Cranberry juice, Placebo juice; Other
Lead sponsor: University of Florida; Other
Eligibility: 30 Years to 55 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Infant Development, Stress
Interventions: Multisensory Early Oral Administration of Human Milk (M-MILK); Other
Lead sponsor: Loyola University; Other
Eligibility: 0 Years to 1 Year
Enrollment: 14 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Maywood, Illinois

Conditions: Healthy
Interventions: Not listed
Lead sponsor: University of Pennsylvania; Other
Eligibility: 25 Years to 35 Years
Enrollment: 6 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2017
U.S. locations: 1
States / cities: Philadelphia, Pennsylvania

Conditions: Fasting
Interventions: Fasting; Other
Lead sponsor: University of California, Davis; Other
Eligibility: 20 Years to 80 Years
Enrollment: 21 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018
U.S. locations: 1
States / cities: Davis, California

Conditions: Insulin Sensitivity
Interventions: Maltodextrin, Synbiotic, Sevelamer; Drug
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Enrollment: 69 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Microbiome, Stress, Food Allergy in Infants
Interventions: Cow's Milk, Soy Milk; Other
Lead sponsor: University of Idaho; Other
Eligibility: 18 Years and older · Female only
Enrollment: 38 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Moscow, Idaho

Conditions: Insulin Sensitivity
Interventions: Sevelamer, Synbiotic, Maltodextrin, High Fat diet, Low Fat diet; Drug · Other
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2020
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Influenza
Interventions: High-Fiber Diet (HFD), Prebiotic Food-Enriched Diet (PreFED); Dietary Supplement
Lead sponsor: M.D. Anderson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 31 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2029
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Gastrointestinal Microbiome
Interventions: Hyaluronan; Dietary Supplement
Lead sponsor: The Cleveland Clinic; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2016 – 2019
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Microbiome, Human, Gastrointestinal Tract
Interventions: Food provided from a commercial meal service provider for a week; Other
Lead sponsor: University of Nebraska Lincoln; Other
Eligibility: 19 Years and older
Enrollment: 65 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2030
U.S. locations: 1
States / cities: Lincoln, Nebraska

Conditions: Healthy
Interventions: Not listed
Lead sponsor: Southwest Regional Wound Care Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Accepts healthy volunteers
Timeline: 2008 – 2009
U.S. locations: 1
States / cities: Lubbock, Texas

Conditions: Colorectal Cancer
Interventions: High taurine and saturated fat diet, Low in taurine and saturated fat diet; Other
Lead sponsor: University of Illinois Chicago; Other
Eligibility: 45 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Chicago, Illinois

Conditions: Infant, Very Low Birth Weight
Interventions: Observational - no intervention; Other
Lead sponsor: Baylor College of Medicine; Other
Eligibility: Up to 3 Days
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2018
U.S. locations: 2
States / cities: Houston, Texas

Conditions: Bacterial Communities
Interventions: Not listed
Lead sponsor: Cornell University; Other
Eligibility: 18 Years and older · Female only
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Ithaca, New York

Conditions: HIV, Non-Alcoholic Fatty Liver Disease, Metabolic-Associated Steatotic Liver Disease
Interventions: Prebiotic, Probiotic; Dietary Supplement
Lead sponsor: Vanderbilt University Medical Center; Other
Eligibility: 18 Years to 89 Years
Enrollment: 63 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Nashville, Tennessee

Conditions: Gut Microbiomes
Interventions: Grape Powder, Placebo Powder; Dietary Supplement · Other
Lead sponsor: Icahn School of Medicine at Mount Sinai; Other
Eligibility: 45 Years to 65 Years
Enrollment: 40 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2027
U.S. locations: 1
States / cities: New York, New York

Conditions: Healthy Volunteers
Interventions: Saccharomyces boulardii, Amoxicillin Clavulanate; Dietary Supplement · Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Human Microbiome
Interventions: Synbiotic, Probiotic, Placebo; Dietary Supplement
Lead sponsor: University of California, San Diego; Other
Eligibility: 65 Years and older
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 1
States / cities: La Jolla, California

Conditions: Very Low Birth Weight Baby, Early Nutrition and the Preterm Infant, Nutritional Requirements, Human Milk Fortification, Human Milk Microbiome, Human Milk Feeding, Human Milk Nutrition, Growth &Amp; Development
Interventions: Opti-NuM is an observational secondary use of data/samples study, the investigators will analyze information and specimens from the MaxiMoM platform RCTs. No interventions form part of this study.; Other
Lead sponsor: The Hospital for Sick Children; Other
Eligibility: 1 Hour to 21 Days
Enrollment: 1,100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2027
U.S. locations: 2
States / cities: Palo Alto, California • San Diego, California

Conditions: Diet Modification
Interventions: Controlled diet with beef raised without antibiotics, Controlled diet with beef produced in conventional systems; Other
Lead sponsor: Purdue University; Other
Eligibility: 21 Years to 69 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: West Lafayette, Indiana

Conditions: Human Microbiome
Interventions: Pomella, Placebo; Dietary Supplement · Other
Lead sponsor: Integrative Skin Science and Research; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2020 – 2021
U.S. locations: 1
States / cities: Sacramento, California

Conditions: Human Gut Microbiota
Interventions: Trametes versicolor extract, Saccharomyces boulardii, Amoxicillin; Dietary Supplement · Drug
Lead sponsor: Beth Israel Deaconess Medical Center; Other
Eligibility: 18 Years to 39 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011 – 2012
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Acquired Immunodeficiency Syndrome, Healthy Volunteers, HIV/AIDS, HIV Diarrhea, Human Immunodeficiency Virus
Interventions: Crofelemer delayed-release tablets 125mg; Drug
Lead sponsor: Napo Pharmaceuticals, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 17 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2021
U.S. locations: 3
States / cities: Tustin, California • Stratford, Connecticut • Springfield, Massachusetts

Conditions: Human Microbiome
Interventions: Probiotic; Dietary Supplement
Lead sponsor: Integrative Skin Science and Research; Industry
Eligibility: 40 Years and older
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Sacramento, California

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Cranberry Polyphenols and Stress Resilience During Multitasking in Healthy Adults

Multisensory Early Oral Administration of Human Milk in Preterm Infants

Exploratory Study of Circadian Relationships Between Social Behavior, Blood Pressure and Metabolomics

Effects of Prolonged Fasting on Microbiome and HDL

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim2)

Investigating the Detection of Bovine and Soy Proteins in Human Milk

Mechanism of Microbiome-induced Insulin Resistance in Humans (Aim 1)

Impact of High Dietary Fiber on Microbiome and Vaccine Responses

Human Pilot Study - HA35 (Hyaluronan Molecular Weight 35) Dietary Supplement for Promoting Intestinal Health

Diet and Microbiome Longitudinal Monitoring With Food Intervention

Study of the Human Skin Microbiome

Diet Modulation of Bacterial Sulfur and Bile Acid Metabolism and Colon Cancer Risk

Growth and Microbiome Development in Very Low Birth Weight Infants Fed Primarily Mother's Own Milk vs. Donor Human Milk

Sources of Bacterial Contamination in Human Milk Samples From the MiLC Trial

The Gut, Liver And Metabolome in Human Immunodeficiency Virus and Non Alcoholic Fatty Liver Disease

Grape Impact on Human Gut Microbiome

Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota

Effects of Triphala and VSL#3 Probiotic Supplementation on Stool Microbiome Profiles and Inflammation

Optimizing Nutrition and Milk (Opti-NuM) Project

Antimicrobial-free Production of Beef Cattle's Affect on Gut Microbiome

Oral Pomegranate Extract on the Microbiome and Skin Biophysical Properties

Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota

Effects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious Diarrhea

Oral Probiotics on the Shift in Gut Microbiome and Skin Carotenoid Levels