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ClinicalTrials.gov public records Last synced Oct 20, 2026, 2:21 PM EDT

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Showing 241–264 of 985 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Microbiome Clear all
Terminated Not applicable Interventional Accepts healthy volunteers

The Role of Microbiome Reprogramming on Liver Fat Accumulation

NCT03914495
View directory record Official record
Conditions
NAFLD
Interventions
Inulin, Placebo
Dietary Supplement
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
35 Years to 65 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Feb 13, 2023 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of a Novel Nutritional Product on Nutrient Gaps and Gut Health in Adults With Occasional Gastrointestinal Issues

NCT06564285
View directory record Official record
Conditions
Gastrointestinal Microbiome, Nutrition, Healthy
Interventions
AG1 - Nutritional Supplement, Placebo
Dietary Supplement
Lead sponsor
Athletic Greens International
Industry
Eligibility
18 Years to 60 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 20, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Providing Personally Tailored Dietary Suggestions Using Individual Microbiome and Glycemic Index Response.

NCT02945514
View directory record Official record
Conditions
Healthy Volunteers
Interventions
DayTwo machine learning algorithm
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
327 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 28, 2018 · Synced Oct 20, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

The Effects of Type 1 Diabetes Mellitus and Increased Weight on Gut Microbiome and Urine Metabolome Profiles in Children

NCT02938806
View directory record Official record
Conditions
Obesity, Overweight, Type 1 Diabetes Mellitus
Interventions
No intervention
Other
Lead sponsor
University of California, San Diego
Other
Eligibility
7 Years to 17 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated May 31, 2022 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional Results available

Multisensory Early Oral Administration of Human Milk in Preterm Infants

NCT06230848
View directory record Official record
Conditions
Infant Development, Stress
Interventions
Multisensory Early Oral Administration of Human Milk (M-MILK)
Other
Lead sponsor
Loyola University
Other
Eligibility
0 Years to 1 Year
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Not listed No phase listed Observational

Microbiome and Bariatric Surgery

NCT03065426
View directory record Official record
Conditions
Weight Change, Body
Interventions
Not listed
Lead sponsor
North Dakota State University
Other
Eligibility
18 Years to 65 Years
Enrollment
144 participants
Timeline
2017 – 2021
U.S. locations
2
States / cities
Fargo, North Dakota • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated May 16, 2017 · Synced Oct 20, 2026, 2:21 PM EDT
Completed No phase listed Observational

Dynamics of the Microbiome in the Premature Infant

NCT02121938
View directory record Official record
Conditions
Infection
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
1 Hour to 1 Week
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2024 · Synced Oct 20, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Phage-based Control and Limitation of Pathobionts for Microbiome Equilibrium and Resilience

NCT07816809
View directory record Official record
Conditions
Gastrointestinal Symptoms, Skin Quality
Interventions
Bacteriophages - MuniPhage, Bacteriophages - RenuPhage, Placebo
Dietary Supplement · Other
Lead sponsor
Colorado State University
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional

The Gut Microbiome As an Indicator of Readiness for Head & Neck Cancer Surgery

NCT05061316
View directory record Official record
Conditions
Cancer of Head and Neck, Nutrition Aspect of Cancer
Interventions
Nestlé Impact Advanced Recovery
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Feb 14, 2025 · Synced Oct 20, 2026, 2:21 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Bladder Environment: Microbiome Oxygen Relationship

NCT02868463
View directory record Official record
Conditions
Urinary Incontinence, UTI's
Interventions
Not listed
Lead sponsor
Loyola University
Other
Eligibility
18 Years and older · Female only
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 20, 2018 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Microbiome Individuality and Stability Over Time

NCT04740684
View directory record Official record
Conditions
Diet
Interventions
Standardized diet
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 70 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 7, 2021 · Synced Oct 20, 2026, 2:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

User Testing of the Evivo Screening Test

NCT03601936
View directory record Official record
Conditions
Gut Microbiome
Interventions
Evivo Infant Gut Bifidobacterium Screening Test
Device
Lead sponsor
Evolve BioSystems, Inc.
Industry
Eligibility
Up to 6 Months
Enrollment
231 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
5
States / cities
Los Angeles, California • Marietta, Georgia • Gresham, Oregon + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Oct 20, 2026, 2:21 PM EDT
Not yet recruiting Not applicable Interventional

Palatable Elemental Diet for Gastrointestinal Symptoms in Chronic Pancreatitis

NCT07559448
View directory record Official record
Conditions
Chronic Pancreatitis
Interventions
Palatable Elemental Diet
Other
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 75 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Redwood City, California
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Completed No phase listed Observational

Time Longitudinal Study of the Microbiome in Colorectal Cancer Subjects

NCT03951792
View directory record Official record
Conditions
Cancer Colon, Gastrointestinal Disease
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 18, 2024 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional

Esophageal Atresia: a Natural Experiment of the Effects of Oral Inoculation on the Gut Microbiome

NCT04901546
View directory record Official record
Conditions
Esophageal Atresia
Interventions
Patient's own saliva
Other
Lead sponsor
Stanford University
Other
Eligibility
Up to 3 Months
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional

The Effects of an Orally-Administered Probiotic on Vaginal Symptoms

NCT07829861
View directory record Official record
Conditions
Vaginal Odor
Interventions
Orally-administered probiotic, Placebo
Dietary Supplement
Lead sponsor
Bonafide Health
Industry
Eligibility
18 Years to 65 Years · Female only
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Harrison, New York
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional

Exercise for Gut Microbiome in Patients With Young-Onset Colorectal Cancer Undergoing Chemotherapy: The COURAGE Trial

NCT06202183
View directory record Official record
Conditions
Colorectal Cancer, Metastatic Colon Cancer, Metastatic Colorectal Cancer
Interventions
Exercise Program
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years to 50 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 11, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional

The Inflammatory Bowel Disease - Anti-Inflammatory Diet (IBD-AID)

NCT04757181
View directory record Official record
Conditions
Inflammatory Bowel Diseases
Interventions
The IBD-AID
Other
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
15 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 21, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dairy Fat and Fermentation Study

NCT05840081
View directory record Official record
Conditions
Heart Diseases, Microbial Colonization, Inflammation
Interventions
Milk or yogurt beverage
Other
Lead sponsor
Tufts University
Other
Eligibility
50 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 12, 2025 · Synced Oct 20, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional

Microbiome Modulation With Prebiotics in PTSD and Cirrhosis

NCT06464952
View directory record Official record
Conditions
Cirrhosis, PTSD
Interventions
Resistant potato starch, Powdered cellulose
Dietary Supplement
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

A Study of a Baby Wash/Shampoo and Baby Lotion Versus Baby Wash/Shampoo Alone for Impact on Skin Barrier and Microbiome on Newborns

NCT05589038
View directory record Official record
Conditions
Healthy
Interventions
Baby Wash/Shampoo, Baby Lotion
Other
Lead sponsor
Johnson & Johnson Consumer Inc. (J&JCI)
Industry
Eligibility
0 Days to 28 Days
Enrollment
53 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Newtown Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 20, 2026, 2:21 PM EDT
Not listed Not applicable Interventional

Prebiotics in Rectal Cancer

NCT05516641
View directory record Official record
Conditions
Rectal Cancer
Interventions
Soluble Corn Fiber, Maltodextrin
Dietary Supplement
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 31, 2023 · Synced Oct 20, 2026, 2:21 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

GBPDC: Gut-Brain in PD Consortium Master Protocol

NCT07567794
View directory record Official record
Conditions
Parkinson Disease (PD), PARKINSON DISEASE (Disorder), Gut Microbiome, Gut Microbiota, Prodromal Parkinsons Disease
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
21 Years to 80 Years
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
7
States / cities
Stanford, California • Chicago, Illinois • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 20, 2026, 2:21 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Goji vs. Fiber on Macular Degeneration

NCT06237127
View directory record Official record
Conditions
Age-Related Macular Degeneration
Interventions
Goji berry, Fiber
Dietary Supplement
Lead sponsor
University of California, Davis
Other
Eligibility
65 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2027
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 17, 2026 · Synced Oct 20, 2026, 2:21 PM EDT