Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.

Clear filters
ClinicalTrials.gov public records Last synced Jul 23, 2026, 8:51 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Middle-aged Adults Clear all
Completed Not applicable Interventional

Acute Exercise on Brain Insulin Sensitivity

NCT05853913
View directory record Official record
Conditions
Aging, Obesity, Insulin Resistance, Cognition, Cardiovascular Disease Risk
Interventions
Exercise
Behavioral
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
40 Years to 80 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
4
States / cities
New Brunswick, New Jersey • Piscataway, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 20, 2025 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Results available

A Community Wellness Program for Adults Living With Long-term Physical Disability

NCT03653390
View directory record Official record
Conditions
Physical Disability
Interventions
EnhanceWellness for Disability (EW-D), Wellness Education
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
45 Years to 64 Years
Enrollment
516 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 20, 2023 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Microgreen Consumption for Healthy Aging

NCT04239898
View directory record Official record
Conditions
Aging, Menopause, Healthy
Interventions
Red cabbage microgreens, Red beet microgreens
Other
Lead sponsor
Colorado State University
Other
Eligibility
45 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jul 23, 2026, 8:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Passive Heat Therapy for Lowering Systolic Blood Pressure and Improving Vascular Function in Mid-life and Older Adults

NCT05300971
View directory record Official record
Conditions
Aging
Interventions
Heat therapy, Thermoneutral water immersion
Other
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
40 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 28, 2025 · Synced Jul 23, 2026, 8:51 AM EDT
Not listed Phase 1Phase 2 Interventional Accepts healthy volunteers

The Effect of Time-restricted Feeding on Physiological Function in Middle-aged and Older Adults

NCT02970188
View directory record Official record
Conditions
Aging
Interventions
Time Restricted Feeding
Behavioral
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
55 Years to 79 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Jul 23, 2026, 8:51 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Vitamin D and Blood Pressure

NCT00459563
View directory record Official record
Conditions
Hypertension
Interventions
Vitamin D, calcitriol, Placebo
Drug
Lead sponsor
Atlanta VA Medical Center
Federal
Eligibility
18 Years to 80 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional

The Effects of Pork vs. Chicken/Fish in a DASH Diet on Blood Pressure Regulation in Middle Aged and Older Adults

NCT01696097
View directory record Official record
Conditions
Hypertension, Dyslipidemias
Interventions
DASH diet counseling
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
40 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 16, 2015 · Synced Jul 23, 2026, 8:51 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Measurement of Insulin Levels in the Cerebrospinal Fluid of Healthy Adults After a Single Intranasal Dose - Middle Age

NCT06434038
View directory record Official record
Conditions
Healthy
Interventions
Low Dose Regular insulin, High Dose Regular insulin, 0.9% Saline
Drug · Other
Lead sponsor
HealthPartners Institute
Other
Eligibility
36 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Paul, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 24, 2025 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

The Effect of 3 Probiotic Strains on Bile Acids, Satiety, and Inflammation

NCT01879098
View directory record Official record
Conditions
Healthy
Interventions
Probiotic: Bacillus subtilis, Lactobacillus plantarum, Bifidobacterium animalis, Placebo
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
35 Years to 65 Years
Enrollment
155 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2014 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Combined Effects of Prolonged Sitting and Mental Stress on the Cardiovascular System

NCT04207333
View directory record Official record
Conditions
Sedentary Behavior, Cardiovascular Risk Factor, Mental Stress, Cognitive Change, Cerebrovascular Insufficiency
Interventions
Mental Arithmetic Test
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
35 Years to 59 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 17, 2023 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

aeRobic Exercise and Cognitive Health

NCT02384993
View directory record Official record
Conditions
Alzheimer's Disease, Aging
Interventions
Enhanced Physical Activity
Behavioral
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
45 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Mar 17, 2024 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Probiotic on Psychological and Cognitive Effects

NCT03080818
View directory record Official record
Conditions
Aging
Interventions
Probiotic - Lactobacillus Rhamnosus GG, Placebo
Dietary Supplement · Other
Lead sponsor
Kent State University
Other
Eligibility
55 Years to 75 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Kent, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 19, 2020 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Results available

A Behavioral Intervention for Depression and Chronic Pain in Primary Care

NCT03265210
View directory record Official record
Conditions
Chronic Pain, Depression
Interventions
RELIEF
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
50 Years and older
Enrollment
73 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
3
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2023 · Synced Jul 23, 2026, 8:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Daily Mixed Spice Consumption on Memory Function

NCT06889961
View directory record Official record
Conditions
Memory, Cognitive Function
Interventions
Mixed spices, Placebo
Dietary Supplement · Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Oral Trehalose Therapy to Reverse Arterial Aging in Middle-Aged and Older Adults

NCT01575288
View directory record Official record
Conditions
Vascular Aging
Interventions
Placebo, High-dose trehalose
Drug
Lead sponsor
University of Colorado, Boulder
Other
Eligibility
50 Years to 79 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boulder, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 10, 2015 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of a Vitality Dietary Supplement on Physical and Mental Function in Middle-aged Adults

NCT01155076
View directory record Official record
Conditions
Health-related Quality of Life
Interventions
Vitality Product, Placebo
Dietary Supplement
Lead sponsor
Pharmanex
Industry
Eligibility
40 Years to 70 Years
Enrollment
116 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
3
States / cities
Tucson, Arizona • Chaska, Minnesota • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 13, 2013 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional

Extending Sleep to Reverse Metabolic Syndrome in Middle-aged Adults: Acceptability and Feasibility of a Sleep Intervention

NCT03599388
View directory record Official record
Conditions
Sleep, Metabolic Syndrome
Interventions
Self- management for adequate sleep intervention (SASI)
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
40 Years to 60 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 14, 2020 · Synced Jul 23, 2026, 8:51 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

The Effectiveness of Over the Counter Hearing Products for Middle-Aged Adults

NCT03511417
View directory record Official record
Conditions
Hearing Loss, Functional
Interventions
over-the-counter hearing device
Device
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
40 Years to 64 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2021 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional

Promoting Medication Adherence Among Older Adults With Hypertension

NCT02846220
View directory record Official record
Conditions
Hypertension
Interventions
Overcoming Immunity to Change health coaching
Behavioral
Lead sponsor
Tulane University School of Medicine
Other
Eligibility
55 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 19, 2020 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Results available

P20 Extending Sleep to Reverse Metabolic Syndrome

NCT03596983
View directory record Official record
Conditions
Metabolic Syndrome
Interventions
Sleep Intervention, Week 2 Intervention
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
35 Years to 60 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 18, 2024 · Synced Jul 23, 2026, 8:51 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Childhood Trauma, Exercise, and Cognition

NCT05972265
View directory record Official record
Conditions
Adverse Childhood Experiences
Interventions
Moderate Intensity Exercise (one day), Placebo - Light Intensity Exercise (one day), Moderate Intensity Exercise (9 wks), Day 1 Assessments, Symptom Measures and Neuropsychological Tests, Day 36 Assessments, Day 57 Assessments, Day 78 Assessments
Behavioral · Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
40 Years to 60 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional

A Tailored Program to Promote Well-being and Physical Activity in Mid-life Adults With Low Physical Activity

NCT04745182
View directory record Official record
Conditions
Middle Aged, Exercise
Interventions
MASTERY
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
45 Years to 64 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 8, 2021 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Assessing Balance Changes Following an Exercise Program Among Middle-Aged Adults

NCT03161236
View directory record Official record
Conditions
Balance Changes
Interventions
home exercise program, non exercise program
Other
Lead sponsor
Loma Linda University
Other
Eligibility
45 Years to 64 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 9, 2019 · Synced Jul 23, 2026, 8:51 AM EDT
Completed Phase 1 Interventional

Telephone-delivered Behavioral Interventions to Reduce Risky Sexual Behavior in HIV-positive Late Middle-age and Older Adults

NCT01499706
View directory record Official record
Conditions
Unsafe Sex
Interventions
1-session of telephone-administered motivational interviewing, 4-session telephone-administered motivational interviewing
Behavioral
Lead sponsor
Ohio University College of Osteopathic Medicine
Other
Eligibility
45 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 25, 2011 · Synced Jul 23, 2026, 8:51 AM EDT