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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Completed Phase 3 Interventional Results available

Sling vs Botox for Mixed Incontinence

NCT04171531
Conditions
Urinary Incontinence, Stress, Urinary Incontinence, Urge
Interventions
Botox® injection, Mid-urethral sling
Drug · Device
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
8
States / cities
Birmingham, Alabama • La Jolla, California • San Diego, California + 5 more
Conditions
Stress Urinary Incontinence, Pelvic Floor Disorders
Interventions
RP Sling, SIS
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Female only
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2032
U.S. locations
5
States / cities
Coconut Creek, Florida • Augusta, Georgia • Chicago, Illinois + 1 more
Completed Not applicable Interventional Accepts healthy volunteers

Postoperative Activity Restrictions After Slings

NCT04552457
Conditions
Stress Urinary Incontinence, Patient Satisfaction, Surgery
Interventions
No activity restrictions, Activity restrictions
Behavioral
Lead sponsor
Northwell Health
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
156 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Great Neck, New York
Completed Not applicable Interventional Results available

TVT-SECUR as an Office-based Procedure

NCT01137539
Conditions
Urinary Incontinence, Stress Urinary Incontinence
Interventions
Gynecare TVT-SECUR system
Device
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
21 Years to 89 Years · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Dearborn, Michigan
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Validated Skills Simulation With the Miya Model

NCT05418764
Conditions
Vaginal Hysterectomy
Interventions
Miyamodel Training
Other
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 80 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Conditions
Stress Urinary Incontinence, Surgical Incision, Pain Vulva
Interventions
Bupivacaine-Meloxicam
Drug
Lead sponsor
TriHealth Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio
Conditions
Stress Urinary Incontinence
Interventions
No post-operative activity restrictions, Standard post-operative activity restriction
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2031
U.S. locations
1
States / cities
Beverly Hills, California
Conditions
Stress Urinary Incontinence, Knowledge, Attitudes, Practice
Interventions
Educational video, Educational leaflet
Other
Lead sponsor
Felicia Lane
Other
Eligibility
18 Years and older · Female only
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Orange, California
Conditions
Stress Urinary Incontinence
Interventions
Cough Test following Sling Surgery
Procedure
Lead sponsor
Michigan Institution of Women's Health PC
Other
Eligibility
21 Years to 89 Years · Female only
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Dearborn, Michigan
Conditions
Bladder Perforation, Retropubic Midurethral Sling, Retropubic Hydrodissection
Interventions
retropubic hydrodissection
Procedure
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Conditions
Pelvic Organ Prolapse, Stress Urinary Incontinence, Satisfaction
Interventions
Online risk calculator
Other
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years and older · Female only
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Completed Not applicable Interventional Accepts healthy volunteers

Trial of Two Techniques to Assess Postoperative Voiding Function

NCT02150083
Conditions
Urinary Retention
Interventions
OR retrograde fill
Procedure
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older · Female only
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Conditions
Patient Satisfaction, Female Sexual Dysfunction
Interventions
Early restriction release, Standard restriction recommendation
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years and older · Female only
Enrollment
155 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Charlotte, North Carolina • Winston-Salem, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers

Patient-Centered Versus Physician-Centered Counseling MidUrethral Sling Videos

NCT03198481
Conditions
Stress Urinary Incontinence, Satisfaction
Interventions
Patient-Centered Counseling Video, Physician Counseling Video
Behavioral
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
2
States / cities
Albuquerque, New Mexico • Austin, Texas
Conditions
Urinary Stress Incontinence
Interventions
3-week post-operative activity restriction, 6-week post-operative activity restriction
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years and older · Female only
Enrollment
206 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
New Haven, Connecticut
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Assessing Pyridium for Post-Sling Urinary Retention

NCT03302936
Conditions
Urinary Retention
Interventions
Phenazopyridine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older · Female only
Enrollment
98 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Accepts healthy volunteers

Comparing Voiding Trials After Midurethral Sling for Stress Incontinence

NCT02400034
Conditions
Stress Urinary Incontinence, Urethral Hypermobility, Cystocele
Interventions
Voiding trial
Other
Lead sponsor
Northwell Health
Other
Eligibility
18 Years and older · Female only
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Great Neck, New York
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Effect of Preoperative Tamsulosin on Postoperative Urinary Retention

NCT05753670
Conditions
Postoperative Retention of Urine
Interventions
Tamsulosin, Placebo
Drug
Lead sponsor
Endeavor Health
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
179 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Evanston, Illinois
Conditions
Postoperative Pain, Opioid Use
Interventions
Liberal post-discharge opioid prescribing, Restricted post-discharge opioid prescribing
Other
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Completed Phase 3 Interventional Results available

Combined Treatment for Mixed Incontinence

NCT01959347
Conditions
Urinary Incontinence, Stress, Urinary Incontinence, Urge
Interventions
Miduretheral Sling, Miduretheral Sling with behavioral/pelvic floor therapy
Procedure · Other
Lead sponsor
NICHD Pelvic Floor Disorders Network
Network
Eligibility
21 Years and older · Female only
Enrollment
480 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
10
States / cities
Birmingham, Alabama • Downey, California • La Jolla, California + 7 more
Conditions
Stress Urinary Incontinence
Interventions
Filled bladder arm
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2025
U.S. locations
1
States / cities
Beverly Hills, California
Conditions
Stress Urinary Incontinence
Interventions
Retropubic midurethral sling
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Portland, Oregon
Conditions
Stress Urinary Incontinence
Interventions
Bupivacaine, Saline, Epinephrine
Drug
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Worcester, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing KIM to TVT Exact Sling

NCT04985799
Conditions
Stress Urinary Incontinence
Interventions
Gynecare TVT Exact Continence System, Neomedic KIM (Knotless Incontinence Mesh)
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
21 Years and older · Female only
Enrollment
147 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Hillsborough, North Carolina • Raleigh, North Carolina