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ClinicalTrials.gov public records Last synced Oct 2, 2026, 9:14 AM EDT

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Showing 49–72 of 661 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Migraine Disease Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Migraine and CVD Risk in Women

NCT03081390
View directory record Official record
Conditions
Migraine
Interventions
Mixed meal tolerance testing, Skin conductance & cold pressor test, Flow-mediated dilation testing
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 35 Years · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 8, 2025 · Synced Oct 2, 2026, 9:14 AM EDT
Terminated Not applicable Interventional

Feasibility of Using a Mobile Device Controlled Micro-pressure Pulse Insufflator for Acute Migraine Relief

NCT03263897
View directory record Official record
Conditions
Migraine
Interventions
insufflation, placebo insufflation
Device
Lead sponsor
Caps Research Network
Other
Eligibility
20 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
2
States / cities
Prescott, Arizona • Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 21, 2022 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional Results available

Brief Behavioral Intervention for Comorbid Migraine and Depression

NCT01775852
View directory record Official record
Conditions
Migraine, Depression
Interventions
ACT-IM
Behavioral
Lead sponsor
Lilian N. Dindo
Other
Eligibility
18 Years to 75 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 22, 2018 · Synced Oct 2, 2026, 9:14 AM EDT
Completed No phase listed Observational

Real-World Evidence (RWE) Data Analysis of 1-year Consecutive Use of Remote Electrical Neuromodulation (REN)

NCT05760638
View directory record Official record
Conditions
Migraine
Interventions
Nerivio
Device
Lead sponsor
Theranica
Industry
Eligibility
12 Years to 99 Years
Enrollment
409 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Nov 22, 2024 · Synced Oct 2, 2026, 9:14 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Diet and Migraine Study

NCT01859052
View directory record Official record
Conditions
Migraine, Obesity
Interventions
Low carbohydrate diet, Low calorie low fat diet, AHA diet recommendations
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
19 Years to 49 Years · Female only
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Sep 2, 2015 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 4 Interventional Results available

Greater Occipital Nerve Block Versus Metoclopramide

NCT03269435
View directory record Official record
Conditions
Migraine
Interventions
Greater occipital nerve block with bupivacaine, Metoclopramide
Procedure · Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 22, 2021 · Synced Oct 2, 2026, 9:14 AM EDT
Terminated Phase 2 Interventional

The Effect of Nasal Carbon Dioxide in the Treatment of Moderate to Severe Migraine

NCT01253915
View directory record Official record
Conditions
Migraine
Interventions
Nasal Carbon Dioxide, Placebo
Drug
Lead sponsor
Capnia, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
3
States / cities
San Diego, California • Bethesda, Maryland • Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 31, 2013 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 3 Interventional Results available

The Efficacy and Tolerability of NP101 Patch in the Treatment of Acute Migraine

NCT00724815
View directory record Official record
Conditions
Migraine Disorders
Interventions
NP101 - Sumatriptan iontophoretic transdermal patch, Placebo
Drug
Lead sponsor
NuPathe Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
530 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
34
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Newport Beach, California + 31 more
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 2, 2026, 9:14 AM EDT
Withdrawn Not applicable Interventional

Is Topiramate Effective in Treating Dizziness in Patient's With Migraine-Associated Dizziness

NCT00732108
View directory record Official record
Conditions
Migraine, Headache, Dizziness
Interventions
topiramate, lactulose placebo pill
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2008
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 6, 2015 · Synced Oct 2, 2026, 9:14 AM EDT
Not listed Phase 4 Interventional Accepts healthy volunteers

Prevention of Menstrual Migraines: Effects of Estrogen Add-back During the HFI in Patients Using Continuous Oral Contraceptives.

NCT01251263
View directory record Official record
Conditions
Menstrual Migraines, Menstrual Bleeding, Menstrual Spotting
Interventions
Estradiol or Placebo
Drug
Lead sponsor
Scott and White Hospital & Clinic
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Dec 1, 2010 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Caffeine/Propranolol Intervention for Acute Migraine

NCT01080677
View directory record Official record
Conditions
Migraine Disorders
Interventions
caffeine/propranolol combination tablet, placebo
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 50 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2017 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Bioequivalency Study of Naratriptan Hydrochloride 2.5 mg Under Fasted Conditions

NCT01161667
View directory record Official record
Conditions
Migraine
Interventions
naratriptan hydrochloride
Drug
Lead sponsor
Roxane Laboratories
Industry
Eligibility
18 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 23, 2018 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 2 Interventional Results available

Normobaric Oxygen (NBO) Therapy in Acute Migraine

NCT01542307
View directory record Official record
Conditions
Migraine
Interventions
Oxygen, Room air
Biological
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2017 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 4 Interventional Results available

Use of the Tx360 Nasal Applicator in the Treatment of Chronic Migraine

NCT01709708
View directory record Official record
Conditions
Chronic Migraine
Interventions
Marcaine, Saline
Drug
Lead sponsor
Tian Medical Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Ann Arbor, Michigan • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 26, 2018 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional

Migraine--Investigational Treatment of Migraine With Noninvasive Brain Stimulation. (tDCS- Migraine)

NCT00521196
View directory record Official record
Conditions
Migraine
Interventions
DC Stimulator (Transcranial Direct Current Stimulator)
Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Oct 2, 2026, 9:14 AM EDT
Completed No phase listed Observational Results available

The Utility of Telemedicine in the Management of Migraine

NCT01706003
View directory record Official record
Conditions
Migraine Headaches
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Lifestyle Modification on Vestibular Migraine

NCT03979677
View directory record Official record
Conditions
Vestibular Migraine
Interventions
Lifestyle Modifications
Behavioral
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Aug 17, 2021 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 2 Interventional

Efficacy and Safety Trial of BHV-2100 for the Acute Treatment of Migraine

NCT06603623
View directory record Official record
Conditions
Migraine
Interventions
BHV-2100, Placebo
Drug
Lead sponsor
Biohaven Therapeutics Ltd.
Industry
Eligibility
18 Years to 64 Years
Enrollment
647 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
60
States / cities
Gilbert, Arizona • Encino, California • Los Alamitos, California + 57 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 2 Interventional

Safety and Efficacy of NPS 1776 in the Acute Treatment of Migraine Headaches

NCT00172094
View directory record Official record
Conditions
Migraine Headache
Interventions
NPS 1776 (800 mg), PLACEBO, NPS 1776 (400 mg)
Drug
Lead sponsor
Shire
Industry
Eligibility
18 Years to 60 Years
Enrollment
189 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
22
States / cities
Huntsville, Alabama • Little Rock, Arkansas • Oceanside, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional

A Study of Family-based Cognitive-behavioral Therapy for Chronic Pediatric Headache and Anxiety

NCT01182051
View directory record Official record
Conditions
Pediatric, Headache, Anxiety
Interventions
CBT or relaxation training
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
7 Years to 17 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 24, 2013 · Synced Oct 2, 2026, 9:14 AM EDT
Terminated Not applicable Interventional Results available

Trial of Nortriptyline and Topiramate in the Initial Treatment of Vestibular Migraine

NCT02169830
View directory record Official record
Conditions
Migraine Disorders
Interventions
nortriptyline, Topiramate, Diet Modification
Drug · Behavioral
Lead sponsor
St. Louis University
Other
Eligibility
18 Years to 70 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 23, 2021 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Phase 3 Interventional

Efficacy & Safety Of Zomig Nasal Spray For Acute Migraine Treatment In Subjects 6 To 11 Years, With OLE

NCT03275922
View directory record Official record
Conditions
Migraine
Interventions
Placebo ZNS, ZNS
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
6 Years to 11 Years
Enrollment
374 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
47
States / cities
Phoenix, Arizona • Little Rock, Arkansas • Anaheim, California + 38 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional Results available

A Research Study to Examine the Difference Between Local Anesthetics Alone and Local Anesthetics Plus Steroids in the Treatment of Chronic Headache

NCT00203294
View directory record Official record
Conditions
Migraine
Interventions
lidocaine, bupivicaine and saline, lidocaine plus bupivicaine plus triamcinolone (steroid)
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 7, 2014 · Synced Oct 2, 2026, 9:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-drug Interventions for Migraines

NCT01545466
View directory record Official record
Conditions
Migraine, Headache
Interventions
Mindfulness Based Stress Reduction (MBSR)
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 12, 2013 · Synced Oct 2, 2026, 9:14 AM EDT