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ClinicalTrials.gov public records Last synced Oct 13, 2026, 5:10 AM EDT

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Showing 217–240 of 742 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Migraine Headache Clear all
Recruiting Not applicable Interventional

Cocoa Extract for Migraine Trial

NCT06808230
View directory record Official record
Conditions
Migraine
Interventions
Cocoa extract, Cocoa extract placebo
Dietary Supplement
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 29, 2026 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 1 Interventional

Study to Evaluate the PK of BMS-927711 in Patient With Migraine During Acute Migraine and Non-migraine Condition

NCT01445067
View directory record Official record
Conditions
Migraine
Interventions
BMS-927711 (CGRP Antagonist)
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
4
States / cities
Glendale, California • Long Beach, California • Orlando, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 1, 2023 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of AJOVY (Fremanezumab-vfrm) on Interictal Migraine Related Burden

NCT04461795
View directory record Official record
Conditions
Migraine
Interventions
Fremanezumab-Vfrm 225 MG/1.5 ML Subcutaneous Solution [AJOVY]
Drug
Lead sponsor
David True
Industry
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
2
States / cities
City of Saint Peters, Missouri • Springfield, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 13, 2022 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Not applicable Interventional Results available

STOPAIN in the Treatment of a Single Migraine Attack

NCT01687101
View directory record Official record
Conditions
Migraine, Headache
Interventions
STOPAIN topical gel
Drug
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years to 65 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 9, 2017 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 4 Interventional

Treatment Patterns Among US Veterans Using Remote Electrical Neuromodulation (REN) for Migraine Treatment

NCT07336420
View directory record Official record
Conditions
Migraine, Acute Treatment of Migraine
Interventions
Nerivio REN device
Device
Lead sponsor
Theranica
Industry
Eligibility
18 Years and older
Enrollment
466 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 3, 2026 · Synced Oct 13, 2026, 5:10 AM EDT
Completed No phase listed Observational Results available

Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP)

NCT01257880
View directory record Official record
Conditions
Migraine With Aura, Patent Foramen Ovale
Interventions
Not listed
Lead sponsor
Swedish Medical Center
Other
Eligibility
18 Years to 55 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
2
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 27, 2011 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 3 Interventional Results available

Evaluation of Galcanezumab in the Prevention of Chronic Migraine

NCT02614261
View directory record Official record
Conditions
Chronic Migraine
Interventions
Galcanezumab, Placebo
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
1,117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
52
States / cities
Phoenix, Arizona • Encino, California • Fullerton, California + 47 more
Source: ClinicalTrials.gov public record
Updated May 18, 2022 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Sphenopalatine Ganglion Block Study

NCT05707754
View directory record Official record
Conditions
Sphenopalatine Ganglion Nerve Block
Interventions
Bupivacaine, angiocatheter
Drug · Device
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 4 Interventional Results available

A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder

NCT04041284
View directory record Official record
Conditions
Migraine, Major Depressive Disorder
Interventions
Fremanezumab, Placebo
Drug
Lead sponsor
Teva Branded Pharmaceutical Products R&D, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
353 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
17
States / cities
Little Rock, Arkansas • San Diego, California • Denver, Colorado + 14 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2023 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 3 Interventional Results available

A Safety Study of Galcanezumab in Participants With Migraine, With or Without Aura

NCT02614287
View directory record Official record
Conditions
Migraine
Interventions
Galcanezumab
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years to 65 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
13
States / cities
Santa Monica, California • Spring Valley, California • Stamford, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Jun 17, 2020 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 1 Interventional

Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness

NCT01669304
View directory record Official record
Conditions
Vestibular Migraine, Chronic Subjective Dizziness
Interventions
Verapamil, Sertraline
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 24, 2015 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 3 Interventional Results available

Metoclopramide for Migraine: A Dose Finding Study

NCT00682734
View directory record Official record
Conditions
Migraine
Interventions
metoclopramide, Diphenhydramine 25mg
Drug
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 69 Years
Enrollment
349 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2018 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Not applicable Interventional

Intervention for Sleep and Pain in Youth

NCT03137147
View directory record Official record
Conditions
Headache Disorders, Migraine Disorders, Insomnia
Interventions
Intervention for Sleep and Pain in Youth
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 17 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 19, 2018 · Synced Oct 13, 2026, 5:10 AM EDT
Completed No phase listed Observational

Association Between Chronic Headache and Back Pain With Childbirth

NCT04091321
View directory record Official record
Conditions
Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain, Anesthesia
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
10 Years and older · Female only
Enrollment
1,112 participants
Timeline
2019 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2021 · Synced Oct 13, 2026, 5:10 AM EDT
Not listed Not applicable Interventional

Auricular Acupuncture vs SOC in Migraine HA

NCT02681211
View directory record Official record
Conditions
Migraine Headache
Interventions
Auricular Acupuncture, Ketorolac 0.5mg/kg, max 30mg, Metoclopramide 0.1 mg/kg, max 10mg, Diphenhydramine 1mg/kg, max 50mg, Normal saline fluid bolus 20mL/kg, max 1000mL
Other · Drug
Lead sponsor
University of Louisville
Other
Eligibility
8 Years to 18 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2024
U.S. locations
2
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 10, 2023 · Synced Oct 13, 2026, 5:10 AM EDT
Recruiting Phase 3 Interventional

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

NCT06810505
View directory record Official record
Conditions
Chronic Migraine
Interventions
Atogepant, Placebo for Atogepant
Drug
Lead sponsor
AbbVie
Industry
Eligibility
12 Years to 17 Years
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2031
U.S. locations
32
States / cities
Huntsville, Alabama • Fayetteville, Arkansas • Little Rock, Arkansas + 29 more
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Not applicable Interventional

ACT for High Frequency Migraine; A Virtual Mindfulness Intervention

NCT05003362
View directory record Official record
Conditions
Migraine
Interventions
ACT
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 27, 2026 · Synced Oct 13, 2026, 5:10 AM EDT
Completed No phase listed Observational

A Research Study To Compare Two Kinds Of Daily Headache

NCT00335803
View directory record Official record
Conditions
Migraine
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
14 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 23, 2009 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Set Point Acupuncture for Migraines Using a Digital Assistant

NCT00714727
View directory record Official record
Conditions
Migraine Headaches
Interventions
acupuncture
Procedure
Lead sponsor
Memorial Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
1
States / cities
Johnstown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 12, 2013 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Not applicable Interventional

Mindfulness and Migraine Research Study

NCT02824250
View directory record Official record
Conditions
Migraine, Chronic Pain
Interventions
MBSR
Behavioral
Lead sponsor
California Pacific Medical Center Research Institute
Other
Eligibility
18 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2020 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 2 Interventional

Efficacy and Safety of BGG492 in the Treatment of Migraine

NCT00892203
View directory record Official record
Conditions
Migraine
Interventions
BGG492, Sumatriptan, Placebo
Drug
Lead sponsor
Novartis
Industry
Eligibility
18 Years to 60 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Glendale, California • Paramount, California
Source: ClinicalTrials.gov public record
Updated Dec 17, 2020 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Phase 4 Interventional Results available

Efficacy and Safety Study of Rimegepant in Episodic Migraine Prevention With Multiple Dosing Regimens

NCT05217927
View directory record Official record
Conditions
Migraine
Interventions
Rimegepant 75mg daily dosing, Rimegepant 75mg every other day dosing, Placebo comparator dosing
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
1,415 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
30
States / cities
Tempe, Arizona • Colton, California • Los Angeles, California + 27 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Oct 13, 2026, 5:10 AM EDT
Completed Not applicable Interventional Results available

Cranial Electrotherapy Stimulation in the Treatment of Migraine Headaches

NCT01265797
View directory record Official record
Conditions
Migraine
Interventions
Cranial Electrostimulator, Sham Device
Device
Lead sponsor
University of Toledo Health Science Campus
Other
Eligibility
18 Years to 65 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 10, 2015 · Synced Oct 13, 2026, 5:10 AM EDT
Completed No phase listed Observational Results available

Prospective ED Headache Cohort Study

NCT00313703
View directory record Official record
Conditions
Headache
Interventions
Not listed
Lead sponsor
Montefiore Medical Center
Other
Eligibility
21 Years and older
Enrollment
477 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2005
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 13, 2026, 5:10 AM EDT