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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mild Traumatic Brain Injury, Concussion Clear all
Recruiting Not applicable Interventional

Advancement of Vestibular Intervention Via Portable Electrical Stimulator (VIPES)

NCT07466589
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion
Interventions
Stochastic Galvanic Vestibular Stimulation (sGVS)
Device
Lead sponsor
Vivonics, Inc.
Industry
Eligibility
18 Years to 55 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Sep 29, 2026, 11:27 AM EDT
Terminated Phase 2 Interventional Accepts healthy volunteers Results available

Sildenafil Treatment for Mild TBI

NCT03598140
View directory record Official record
Conditions
Vascular System Injuries, Concussion, Brain, Post-Concussion Syndrome
Interventions
Sildenafil Citrate, Placebo oral capsule
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 18, 2020 · Synced Sep 29, 2026, 11:27 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Utility of Pupillary Metrics in Diagnosis and Management of Concussion in Children

NCT04540445
View directory record Official record
Conditions
Brain Concussion, Reflex, Pupillary, Post-Concussion Syndrome, Brain Injuries, Traumatic
Interventions
Pupillary Assessment
Other
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
5 Years to 17 Years
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2022 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Use of 31P MRS to Assess Brain NAD+ in Healthy Current and Former Collegiate Athletes

NCT02721537
View directory record Official record
Conditions
Concussion, Mild
Interventions
Nicotinamide Riboside, Matching placebo
Dietary Supplement · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
2
States / cities
Minneapolis, Minnesota • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 2, 2022 · Synced Sep 29, 2026, 11:27 AM EDT
Terminated No phase listed Observational

Role of NSI in Differentiating Between Mild Traumatic Brain Injury And Behavioral Health Conditions

NCT01502839
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussive Symptoms, Post-Traumatic Stress Disorder
Interventions
No Intervention
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
887 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2017 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Active Injury Management (AIM) After Pediatric Concussion

NCT03869970
View directory record Official record
Conditions
Brain Concussion
Interventions
REST, ACTIVITY, mHEALTH
Behavioral
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
11 Years to 24 Years
Enrollment
237 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 14, 2023 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional Results available

Evaluation of a Sensory Enrichment Multimodal Device (SEMD) on Physical Therapy Patients With Disequilibrium

NCT01483937
View directory record Official record
Conditions
Vestibular Diseases, Labyrinth Diseases, Ear Diseases, Otorhinolaryngologic Diseases, Traumatic Brain Injury
Interventions
Usual care physical therapy plus SEMD, Usual care physical therapy only
Device · Other
Lead sponsor
Karen L Atkins
Industry
Eligibility
21 Years to 84 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
4
States / cities
Garden Grove, California • Celebration, Florida • Fort Myers, Florida + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 26, 2014 · Synced Sep 29, 2026, 11:27 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Passive Neurosensory Reintegration Training as a Tool to Augment Mild Traumatic Brain Injury

NCT07356167
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Passive neurosensory reintegration training (PNRT)
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Building Emotional Self-Awareness Teletherapy (BEST)

NCT05623046
View directory record Official record
Conditions
Concussion, Mild, Concussion, Brain, Concussion, Severe, Concussion, Intermediate, Concussion; Syndrome, Concussion Injury of Cerebrum, Concussion with Brief Loss of Consciousness, Alexithymia
Interventions
Treatment
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional

Standardized Instruments to Provide Diagnostic and Prognostic Information in Mild Traumatic Brain Injury (mTBI)

NCT04372797
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Diagnostic test
Device
Lead sponsor
Carey Balaban
Other
Eligibility
18 Years to 50 Years
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
3
States / cities
San Diego, California • Miami, Florida • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparing and Interactive Concussion Education Platform to Current Education Standards

NCT04122274
View directory record Official record
Conditions
Concussion, Brain
Interventions
NCAA education sheet, Sham Intervention, Decision-based interactive concussive education platform
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 16, 2022 · Synced Sep 29, 2026, 11:27 AM EDT
Completed No phase listed Observational

Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)

NCT02812225
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
BrainPulse
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
5 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 29, 2026, 11:27 AM EDT
Completed No phase listed Observational

Accelerated Transcranial Magnetic Stimulation Intervention for Post-Concussion Syndrome

NCT07211919
View directory record Official record
Conditions
Post Concussive Syndrome, Chronic, Post Concussion Symptoms, Post Concussive Syndrome, Post Concussion Syndrome, Anxiety Disorder Not Otherwise Specified
Interventions
Not listed
Lead sponsor
Cognitive FX
Industry
Eligibility
16 Years to 75 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Provo, Utah
Source: ClinicalTrials.gov public record
Updated Oct 9, 2025 · Synced Sep 29, 2026, 11:27 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Cortical Plasticity Assessment in Athletes With a History of Concussion

NCT01112761
View directory record Official record
Conditions
Concussion
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 30 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Sep 29, 2026, 11:27 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Acute Concussion and Melatonin

NCT04731974
View directory record Official record
Conditions
Concussion, Mild, Concussion, Brain, Pediatric ALL
Interventions
Melatonin 3 MG, Placebo
Drug · Other
Lead sponsor
Children's National Research Institute
Other
Eligibility
12 Years to 18 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2024 · Synced Sep 29, 2026, 11:27 AM EDT
Not yet recruiting Not applicable Interventional

Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for Decreasing Concussion Recovery Timeline and Symptom Load

NCT07642739
View directory record Official record
Conditions
Concussion (Diagnosis)
Interventions
Nature-based Guided Awareness Group, Standard Guided Awareness Group
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
14 Years to 35 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Sep 29, 2026, 11:27 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

The RETINA Project: Reliable Eye Tracking in Neurocognitive Assessment of Traumatic Brain Injury

NCT01552577
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years and older
Enrollment
183 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 16, 2018 · Synced Sep 29, 2026, 11:27 AM EDT
Active, not recruiting Not applicable Interventional

Brain Stimulation for Concussion

NCT05889117
View directory record Official record
Conditions
Transcranial Magnetic Stimulation, Magnetic Resonance Imaging, Neuropsychological Tests, Traumatic Brain Injury, Post-Concussion Syndrome
Interventions
Intermittent theta-burst treatment (iTBS) using MagPro Transcranial Magnetic Stimulator (manufacturer: Magventure)
Device
Lead sponsor
The Mind Research Network
Other
Eligibility
18 Years to 64 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Sep 29, 2026, 11:27 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients

NCT00580918
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
functional magnetic resonance imaging fMRI
Other
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2003
U.S. locations
1
States / cities
Irvine, California
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 29, 2026, 11:27 AM EDT
Active, not recruiting Phase 1 Interventional

Tele-Rehabilitation to Improve Mild Traumatic Brain Injury Recovery and Reduce Subsequent Injury Risk

NCT05594225
View directory record Official record
Conditions
Brain Concussion
Interventions
Virtual Neuromuscular/Dual-Task Training
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 40 Years
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketone Supplementation in Adolescents Post-Concussion

NCT04079907
View directory record Official record
Conditions
Concussion, Mild, Concussion, Severe, Concussion, Brain, Concussive Injury, Sport Injury, Sports Injuries in Children
Interventions
Ketone, Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 19 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 29, 2026, 11:27 AM EDT
Not yet recruiting Not applicable Interventional

Female Concussion Head Cooling

NCT07303933
View directory record Official record
Conditions
Concussion (Diagnosis), Concussion Post Syndrome, Concussion, Mild
Interventions
Brain Cooling
Device
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 27 Years · Female only
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Sep 29, 2026, 11:27 AM EDT
Completed Not applicable Interventional Results available

Traditional Balance vs Vibrotactile Feedback Training for Vestibular Rehabilitation

NCT01672658
View directory record Official record
Conditions
Traumatic Brain Injury, Vestibular Deficits
Interventions
Sensory Kinetics Balance System, Traditional Vestibular Rehabilitation
Device · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 75 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 3, 2016 · Synced Sep 29, 2026, 11:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Normative Datasets for Assessments Planned for Mild Traumatic Brain Injury (NORMAL)

NCT01925963
View directory record Official record
Conditions
Focus: Healthy Adults Without Brain Injury
Interventions
Not listed
Lead sponsor
Lindell Weaver
Other
Eligibility
18 Years to 65 Years
Enrollment
83 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
2
States / cities
Colorado Springs, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 26, 2018 · Synced Sep 29, 2026, 11:27 AM EDT