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ClinicalTrials.gov public records Last synced Jul 21, 2026, 11:34 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mobility Disability Clear all
Completed Early Phase 1 Interventional

Adapted High-Intensity Virtual Reality Exergaming

NCT07155213
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Virtual reality exergaming
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 25 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional

Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion

NCT03157349
View directory record Official record
Conditions
Acute Pain, Neck Pain
Interventions
Biofreeze, Placebo
Other
Lead sponsor
Sport and Spine Rehab Clinical Research Foundation
Other
Eligibility
18 Years to 65 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Landover, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Not applicable Interventional

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

NCT05964829
View directory record Official record
Conditions
Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting, Multiple Sclerosis, Chronic Progressive
Interventions
Cionic Neural Sleeve NS-100, Walking Program
Device · Behavioral
Lead sponsor
Cionic, Inc.
Industry
Eligibility
22 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional

Advanced Virtual Exercise Environment Device for Use by Persons With Physical Disabilities

NCT02990507
View directory record Official record
Conditions
Physically Disabled
Interventions
AVEED: Arm rotation, video display, AVEED: Arm rotation, without video display, AVEED: Leg rotation, arm-energy input, video display, AVEED: Leg rotation, arm-energy input, without video display
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Phase 3 Interventional Results available

The LIFE Study - Lifestyle Interventions and Independence for Elders

NCT01072500
View directory record Official record
Conditions
Sedentary Lifestyle, Risk of Disability, Aging
Interventions
Physical Activity, Successful Aging
Behavioral
Lead sponsor
University of Florida
Other
Eligibility
70 Years to 89 Years
Enrollment
1,635 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
8
States / cities
Palo Alto, California • New Haven, Connecticut • Gainesville, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Jul 21, 2026, 11:34 PM EDT
Not yet recruiting Not applicable Interventional

Reduction of Depression in People With Disabilities Through Dual Treatment: Digital CBT & NBHWC Coaching

NCT07195292
View directory record Official record
Conditions
Hearing Disability, Depression, Mobility Disability
Interventions
Sham Digital Program - General health education and interactive quizzes unrelated to depression or CBT., Toivoa-002 - A digital Cognitive Behavioral Therapy program combined with NBHWC-certified coaching.
Device
Lead sponsor
Toivoa Inc
Industry
Eligibility
22 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
4
States / cities
Dover, Delaware • East Orange, New Jersey • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Phase 1Phase 2 Interventional

Cocoa to Maximize Exercise Training in Older Adults - The COMET Trial

NCT07161726
View directory record Official record
Conditions
Mobility Disability
Interventions
(-)-Epicatechin-rich cocoa supplementation combined with exercise training, Placebo combined with exercise training
Combination Product
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
55 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Not applicable Interventional

Harness-based Mobility Intervention for Infants With Down Syndrome

NCT06219863
View directory record Official record
Conditions
Down Syndrome
Interventions
Body weight supported harness
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
Up to 2 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional

Healthy Weight and Stress Management Study

NCT05279989
View directory record Official record
Conditions
Physical Disability, Obesity, Muscle Weakness, Anxiety, Depression
Interventions
Seated Tai Chi Qigong, Health Information Videos
Other
Lead sponsor
Arizona State University
Other
Eligibility
35 Years to 64 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Vitality, Independence, and Vigor in Elders Study I Clinical Trial

NCT01198886
View directory record Official record
Conditions
Functionally Limited, Sedentary
Interventions
Successful Aging Program, Exercise-Nutrition Program
Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years and older
Enrollment
121 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
17
States / cities
Arlington, Massachusetts • Ayer, Massachusetts • Boston, Massachusetts + 10 more
Source: ClinicalTrials.gov public record
Updated May 12, 2015 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Not applicable Interventional

Phase 4 of Designed With You

NCT07157995
View directory record Official record
Conditions
Disability Physical
Interventions
BALANCE Building Active LIving and Addressing Needs for Caregiver Empowerment
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Not applicable Interventional

Mindfulness, Exercise, and Nutrition To Optimize Resilience (MENTOR)

NCT06560619
View directory record Official record
Conditions
Disabled Persons
Interventions
MENTOR
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 26, 2024 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Community-based Functional Fitness for Adults Aging With Mobility Disability

NCT07283510
View directory record Official record
Conditions
Mobility Disability, Older Adults
Interventions
Functional Fitness
Behavioral
Lead sponsor
University of Kansas
Other
Eligibility
60 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Jul 21, 2026, 11:34 PM EDT
Terminated Not applicable Interventional

Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria

NCT00785135
View directory record Official record
Conditions
Binocular Dysfunction, Vertical Heterophoria, Vision, Binocular, Vision Disparity
Interventions
Lenses containing prismatic correction, Lenses not containing prismatic correction
Device
Lead sponsor
Vision Specialists of Birmingham
Other
Eligibility
14 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Birmingham, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 11, 2020 · Synced Jul 21, 2026, 11:34 PM EDT
Not yet recruiting Not applicable Interventional

Impact of Loss Aversion Messaging and Anticipated Regret for Inaction on Exercise Adherence in Older Adults

NCT07540052
View directory record Official record
Conditions
Mobility Disability, Walking Difficulty
Interventions
Brief Daily At-Home Strength Training Program, Loss Aversion Messaging, Standard Adherence Reminder Messaging
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
65 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility of An Active Video Gaming Intervention

NCT05310279
View directory record Official record
Conditions
Physical Disability
Interventions
GAIMplank
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Homewood, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

The LIFE Study: Lifestyle Interventions and Independence for Elders, Pilot

NCT00116194
View directory record Official record
Conditions
Physically Challenged, Aging
Interventions
Physical Activity
Behavioral
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
70 Years to 89 Years
Enrollment
424 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
4
States / cities
Palo Alto, California • Winston-Salem, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 24, 2010 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

On the Move: Optimizing Participation in Group Exercise

NCT01986647
View directory record Official record
Conditions
Physical Disability
Interventions
On the Move exercise - exercise leader, Standard program - exercise leader, On the Move exercise - staff activity personnel, Standard program - staff activity personnel
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
424 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 21, 2019 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Not applicable Interventional

Effectiveness of Frontal Plane Adaptability in a Novel Foot Prosthesis

NCT06214026
View directory record Official record
Conditions
Amputation
Interventions
META-Arc foot locked, META-Arc foot unlocked
Device
Lead sponsor
University of Washington
Other
Eligibility
16 Years and older
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Tampa, Florida • Mount Sterling, Ohio • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 22, 2024 · Synced Jul 21, 2026, 11:34 PM EDT
Completed No phase listed Observational

Osteoarthritis: Weakness From Inflammation

NCT00104312
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2009 · Synced Jul 21, 2026, 11:34 PM EDT
Recruiting Phase 2 Interventional

Proof-of-Concept Study Evaluating Total Body Weight, Physical Function & Safety of Enobosarm in Patients Treated With GLP-1 Receptor Agonist, for Weight Loss

NCT07446998
View directory record Official record
Conditions
Obesity & Overweight, Mobility Disability, HOMA-IR
Interventions
Enobosarm, Semaglutide (Wegovy) weekly injection
Drug
Lead sponsor
Veru Inc.
Industry
Eligibility
65 Years to 100 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
14
States / cities
Phoenix, Arizona • Doral, Florida • Miami, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

HIFT for People With Mobility-Related Disabilities

NCT05516030
View directory record Official record
Conditions
Mobility Limitation, Physical Disability
Interventions
HIFT for people with MRD
Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 24, 2022 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional

Up, Down, and All Around: Evaluating Mobility Devices for Young Children With Developmental Disabilities and Delays

NCT06591559
View directory record Official record
Conditions
Down Syndrome, Gross Motor Delay, Cerebral Palsy
Interventions
Permobil Explorer Mini, Portable Mobility Aid for Children (PUMA)
Device
Lead sponsor
University of Washington
Other
Eligibility
12 Months to 60 Months
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 3, 2026 · Synced Jul 21, 2026, 11:34 PM EDT
Completed Not applicable Interventional

The Effects of Virtual Zumba® in Individuals With Developmental Disabilities

NCT05198232
View directory record Official record
Conditions
Developmental Disability, Autism Spectrum Disorder, Down Syndrome, Cerebral Palsy
Interventions
Zumba High Tempo, Zumba Low Tempo
Behavioral
Lead sponsor
Auburn University
Other
Eligibility
18 Years to 75 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated May 4, 2022 · Synced Jul 21, 2026, 11:34 PM EDT