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ClinicalTrials.gov public records Last synced Oct 17, 2026, 7:46 PM EDT

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Showing 1–24 of 136 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Mobility Limitation Clear all
Completed Not applicable Interventional Results available

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

NCT04550676
View directory record Official record
Conditions
Hiv, Fatigue, Mobility Limitation
Interventions
HIIT (intervention), CME (active control), Coaching, Control text message
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional

Dry Needling and Stretching vs. Stretching Alone on Hamstring Flexibility in Patients With Knee Pain

NCT02498704
View directory record Official record
Conditions
Mobility Limitation
Interventions
Dry Needling, Sham Needling
Procedure · Other
Lead sponsor
Keller Army Community Hospital
Federal
Eligibility
18 Years to 40 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Point, New York
Source: ClinicalTrials.gov public record
Updated Feb 23, 2016 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Life 2: Improving Fitness and Function in Elders

NCT00435188
View directory record Official record
Conditions
Aging, Mobility Limitations
Interventions
Multi-component physical activity counseling program
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
70 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 9, 2015 · Synced Oct 17, 2026, 7:46 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mobility Assessment Using Surrogates in Elderly Participants

NCT03032341
View directory record Official record
Conditions
Mobility Limitation
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
70 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Live Long Walk Strong (LLWS) Rehabilitation Program: What Features Improve Mobility Skills

NCT04026503
View directory record Official record
Conditions
Mobility Limitation
Interventions
Live Long Walk Strong rehabilitation program
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
151 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Recruiting Not applicable Interventional

Walk On! National Council on Aging Innovation Lab

NCT07368907
View directory record Official record
Conditions
Falls Prevention
Interventions
Walk On! Program
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 29, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhancing Independence Using Group-based Community Interventions for Healthy AGing in Elders: the ENGAGE Pilot Study

NCT03430271
View directory record Official record
Conditions
Mobility Limitation
Interventions
Physical Activity Intervention, Healthy Aging Intervention
Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years to 89 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Boston, Massachusetts • Somerville, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 14, 2018 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Sensorimotor Locus of Balance Control in Elderly Gait

NCT03341728
View directory record Official record
Conditions
Ambulation Difficulty, Gait, Unsteady, Fall, Position Sense Disorders
Interventions
Optical flow perturbations, Normal walking
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
65 Years and older
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 5, 2019 · Synced Oct 17, 2026, 7:46 PM EDT
Completed No phase listed Observational

Biomechanical Assessment of Level Gait in Patient's Status Post Bladder Exstrophy

NCT00863070
View directory record Official record
Conditions
Bladder Exstrophy
Interventions
Not listed
Lead sponsor
Connecticut Children's Medical Center
Other
Eligibility
4 Years to 65 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
2
States / cities
Farmington, Connecticut • Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 20, 2017 · Synced Oct 17, 2026, 7:46 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)

NCT07805044
View directory record Official record
Conditions
PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness, Cardiometabolic Risk Factors, Mobility Limitation
Interventions
Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
Procedure · Other
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2041
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Emotional, Physical and Cognitive Benefits of Purposeful Green Space Activities on Seniors

NCT04913363
View directory record Official record
Conditions
Loneliness, Social Isolation, Mood, Well Aging, Physical Activity, Mobility Limitation
Interventions
Green space
Other
Lead sponsor
University of Virginia
Other
Eligibility
65 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Results available

Impact of More Frequent PT Services

NCT04778475
View directory record Official record
Conditions
Mobility Limitation, Physical Disability, Stroke, Acute
Interventions
Intensive therapy, Standard of care therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2023 · Synced Oct 17, 2026, 7:46 PM EDT
Recruiting Phase 2 Interventional

Fisetin to Reduce Senescence and Mobility Impairment in PAD

NCT06399809
View directory record Official record
Conditions
Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty, Claudication
Interventions
Fisetin, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Active, not recruiting Not applicable Interventional

Randomized Clinical Trial to Improve Mobility After Hospitalization

NCT05736484
View directory record Official record
Conditions
Hypertension, Diabetes, Heart Failure, Ambulatory Difficulty, Mobility Limitation
Interventions
Social Support Gamification
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
50 Years and older
Enrollment
350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Results available

Exercise and Weight Loss in PAD

NCT02607033
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Exercise, Weight Loss
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 90 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 17, 2024 · Synced Oct 17, 2026, 7:46 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing the Reciprocal Inhibition Method and Post-isometric Inhibition Method of Muscle Energy Technique on the Spinal Reflex Excitability in Healthy Subjects

NCT03980106
View directory record Official record
Conditions
Relaxation; Joint, Limitation, Mobility, Relaxation; Lumbosacral
Interventions
Reciprocal Inhibition Muscle Energy Technique, Post-Isometric Inhibition Muscle Energy Technique
Other
Lead sponsor
University of North Georgia
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Dahlonega, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional

Relationships Between Exercise and Emotion Regulation on Physical Activity in Frail Older Adults

NCT03514160
View directory record Official record
Conditions
Mobility Limitation, Sedentary Lifestyle, Older Adults
Interventions
Group exercise
Behavioral
Lead sponsor
Northeastern University
Other
Eligibility
60 Years to 90 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 2, 2018 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Phase 2 Interventional

Restoring Skill in Walking

NCT00177359
View directory record Official record
Conditions
Mobility Limitation
Interventions
gait intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
65 Years and older
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 13, 2007 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional

Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke

NCT01180738
View directory record Official record
Conditions
Stroke, Difficulty Walking
Interventions
Body weight supported treadmill training, Overground walking training
Behavioral
Lead sponsor
Stephanie Miller
Other
Eligibility
21 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 2, 2020 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reflex Excitability in Post-stroke Stiff-Knee Gait

NCT04947865
View directory record Official record
Conditions
Stroke, Chronic Stroke, Gait, Hemiplegic, Gait, Spastic, Gait Disorder, Sensorimotor, Gait Disorders, Neurologic, Walking, Difficulty
Interventions
Peripheral nerve stimulation, Commercial knee brace
Other · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years and older
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 4, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

IText For ICOUGH: Improving Ambulation of Surgical Patients Through Text Messaging

NCT03834428
View directory record Official record
Conditions
Ambulation Difficulty
Interventions
Text Message Intervention, ICOUGH protocol
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 16, 2019 · Synced Oct 17, 2026, 7:46 PM EDT
Not yet recruiting Not applicable Interventional

Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project

NCT03530592
View directory record Official record
Conditions
Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Foot Drop, Mobility Limitation
Interventions
Seated Ankle Robot Training
Device
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
18 Years to 88 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 21, 2018 · Synced Oct 17, 2026, 7:46 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effects of resO™ Bone and Joint Support Postbiotic on Physical Function, Pain Interference, and Mobility in Adults With Joint Discomfort

NCT07602426
View directory record Official record
Conditions
Joint Discomfort, Musculoskeletal Pain, Mobility Limitation
Interventions
Placebo, Supplement
Other · Dietary Supplement
Lead sponsor
Able Biolabs, LLC
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 22, 2026 · Synced Oct 17, 2026, 7:46 PM EDT
Recruiting Phase 3 Interventional

SMART Exercise for PAD

NCT06032065
View directory record Official record
Conditions
Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty
Interventions
Supervised Treadmill Exercise, Home-Based Exercise, Nitrate-rich beetroot Juice
Behavioral · Dietary Supplement
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Chicago, Illinois • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 17, 2026, 7:46 PM EDT