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Showing 1–24 of 130 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mobility Limitations Clear all
Completed Not applicable Interventional

Use Of Gigstride Device In Patients With Lower Extremity Deficit

NCT06548087
View directory record Official record
Conditions
Ambulation Difficulty, Lower Extremity Problem
Interventions
Gigstride Ambulatory Device
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Nov 5, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Life 2: Improving Fitness and Function in Elders

NCT00435188
View directory record Official record
Conditions
Aging, Mobility Limitations
Interventions
Multi-component physical activity counseling program
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
70 Years and older
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 8, 2015 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Remediation to Improve Mobility in Sedentary Seniors

NCT02567227
View directory record Official record
Conditions
Mobility Limitation, Motor Activity, Difficulty Walking, Cognitive Ability General
Interventions
Cognitive Remediation, Active Control
Other
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
70 Years and older
Enrollment
383 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Sep 6, 2026, 8:27 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Truway Whole-Body Digital Twin and Physiologic Resilience Study (TRU-OMNIBODY)

NCT07805044
View directory record Official record
Conditions
PHYSIOLOGICAL PHENOMENA, Homeostasis, Physical Functional Performance, Cardiorespiratory Fitness, Cardiometabolic Risk Factors, Mobility Limitation
Interventions
Standardized Physiologic Resilience Challenge, Multimodal Whole-Body Physiologic Monitoring, Research-Only Whole-Body Digital Twin Analysis
Procedure · Other
Lead sponsor
Truway Health, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
450 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2041
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Sep 3, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Recruiting Phase 2 Interventional

Fisetin to Reduce Senescence and Mobility Impairment in PAD

NCT06399809
View directory record Official record
Conditions
Peripheral Arterial Disease, Aging, Peripheral Vascular Diseases, Walking, Difficulty, Claudication
Interventions
Fisetin, Placebo
Drug
Lead sponsor
Northwestern University
Other
Eligibility
50 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 14, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Not yet recruiting Not applicable Interventional

Seated Ankle Robot for Foot Drop in Aging and Disabled Populations: A Demonstration Project

NCT03530592
View directory record Official record
Conditions
Peripheral Nervous System Diseases, Gait Disorders, Neurologic, Foot Drop, Mobility Limitation
Interventions
Seated Ankle Robot Training
Device
Lead sponsor
Baltimore VA Medical Center
Federal
Eligibility
18 Years to 88 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 20, 2018 · Synced Sep 6, 2026, 8:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cortical Processes During Walking Post-stroke

NCT05710029
View directory record Official record
Conditions
Stroke, Acute, Walking, Difficulty
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

BAILA: Being Active, Increasing Latinos Healthy Aging

NCT01988233
View directory record Official record
Conditions
Mobility Limitation
Interventions
BAILAMOS© Dance Program, Health Education Control Group
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
55 Years and older
Enrollment
333 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
12
States / cities
Bellwood, Illinois • Berwyn, Illinois • Chicago, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 26, 2022 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Heat Therapy, Functional Capacity, and Vascular Health in Older Adults

NCT05706181
View directory record Official record
Conditions
Aging Well, Walking, Difficulty, Hyperemia
Interventions
Home-based leg heat therapy, Home-based sham therapy
Other
Lead sponsor
University of North Texas Health Science Center
Other
Eligibility
55 Years to 80 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Recruiting Not applicable Interventional

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

NCT05661084
View directory record Official record
Conditions
Dementia, Memory Loss, Alzheimer Disease, Executive Dysfunction, Mobility Limitation
Interventions
Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active), Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham), Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham), Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (active)
Device
Lead sponsor
Hebrew SeniorLife
Other
Eligibility
55 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Results available

High-Intensity Exercise to Attenuate Limitations and Train Habits in Older Adults With HIV

NCT04550676
View directory record Official record
Conditions
Hiv, Fatigue, Mobility Limitation
Interventions
HIIT (intervention), CME (active control), Coaching, Control text message
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
118 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
Aurora, Colorado • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Results available

HOMEStudy: Development of a Home-based Self-delivered Prehabilitation Intervention to Proactively Reduce Fall Risk in Older Adults

NCT05583578
View directory record Official record
Conditions
Mobility Limitation, Aging
Interventions
Home-based mobility testing and active tDCS, Sham tDCS
Device
Lead sponsor
University of Florida
Other
Eligibility
70 Years to 95 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional

Functional Activity Strength Training

NCT05697497
View directory record Official record
Conditions
Walking, Difficulty
Interventions
Daily exercise intervention
Behavioral
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
65 Years and older
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional

Effects of a Home Based Walking Program Using Rhythmic Auditory Stimulation in Patients With Multiple Sclerosis

NCT02065284
View directory record Official record
Conditions
Multiple Sclerosis, Ambulation Difficulty
Interventions
Rhythmic Auditory Stimulation (RAS)
Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 20, 2022 · Synced Sep 6, 2026, 8:27 AM EDT
Recruiting Not applicable Interventional

Assisted Ambulation to Improve Health Outcomes for Older Medical Inpatients

NCT05725928
View directory record Official record
Conditions
Mobility Limitation, Frailty, Hospital Acquired Condition, Weakness, Muscle
Interventions
Mobility technician
Behavioral
Lead sponsor
The Cleveland Clinic
Other
Eligibility
65 Years and older
Enrollment
3,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
5
States / cities
Springfield, Massachusetts • Cleveland, Ohio • Garfield Heights, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2026 · Synced Sep 6, 2026, 8:27 AM EDT
Recruiting Phase 3 Interventional

Improving Mobility After Revascularization in Peripheral Artery Disease

NCT06686121
View directory record Official record
Conditions
Peripheral Artery Disease, Intermittent Claudication, Peripheral Vascular Disease, Mobility Limitation, Revascularization
Interventions
Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control, Placebo Beetroot Juice Without Nitrate
Behavioral · Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
386 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2032
U.S. locations
7
States / cities
Tucson, Arizona • Downey, California • Atlanta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Phase 2 Interventional

Increasing Physical Activity Among Overweight Women With Mobility Disabilities.

NCT00164515
View directory record Official record
Conditions
Obesity
Interventions
Personalized exercise programme (PEP)
Behavioral
Lead sponsor
Centers for Disease Control and Prevention
Federal
Eligibility
18 Years to 75 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 25, 2019 · Synced Sep 6, 2026, 8:27 AM EDT
Not yet recruiting Not applicable Interventional

Developing a Nonpharmacological Pain Intervention for Community-dwelling Older Adults With Dementia

NCT06264362
View directory record Official record
Conditions
Pain, Chronic, Dementia, Mild, Mobility Limitation, Physical Disability, Osteo Arthritis Knee, Mild Cognitive Impairment
Interventions
Tailored Physical Activity Program
Behavioral
Lead sponsor
Drexel University
Other
Eligibility
60 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 10, 2025 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Results available

Home Exercise to Enhance Mobility for Older Diabetics

NCT01308008
View directory record Official record
Conditions
Diabetes Mellitus Type 2
Interventions
home exercise/physical activity (PA) enhancement program with behavioral support, flex and toning health education program
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 7, 2018 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Early Phase 1 Interventional

Kinesio Taping Effectiveness on Idiopathic Toe Walking

NCT02025582
View directory record Official record
Conditions
Idiopathic Toe Walking
Interventions
Kinesio Tape of the Ankle
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 10 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Not applicable Interventional Results available

Impact of More Frequent PT Services

NCT04778475
View directory record Official record
Conditions
Mobility Limitation, Physical Disability, Stroke, Acute
Interventions
Intensive therapy, Standard of care therapy
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 80 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Dec 17, 2023 · Synced Sep 6, 2026, 8:27 AM EDT
Not listed Not applicable Interventional

Use of Pedometer Following Radical Prostatectomy

NCT04206280
View directory record Official record
Conditions
Prostate Cancer, Ambulation Difficulty
Interventions
Use of a pedometer following surgery, Standard of care
Behavioral
Lead sponsor
Benaroya Research Institute
Other
Eligibility
18 Years to 75 Years · Male only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Feb 10, 2020 · Synced Sep 6, 2026, 8:27 AM EDT
Completed Phase 2 Interventional Results available

Clinical Study for the Treatment of Adhesive Capsulitis of the Shoulder

NCT02006719
View directory record Official record
Conditions
Adhesive Capsulitis, Frozen Shoulder
Interventions
Collagenase Clostridium Histolyticum, Placebo
Biological · Other
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
322 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
35
States / cities
Birmingham, Alabama • Mobile, Alabama • Phoenix, Arizona + 31 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Sep 6, 2026, 8:27 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Mobility Assessment Using Surrogates in Elderly Participants

NCT03032341
View directory record Official record
Conditions
Mobility Limitation
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
70 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Sep 6, 2026, 8:27 AM EDT