- Conditions
- Moderate to Advanced Chronic Periodontitis
- Interventions
- locally-applied minocycline HCl (1 mg), scaling and root planing (Sc/RP)
- Drug · Procedure
- Lead sponsor
- University of Nebraska
- Other
- Eligibility
- 40 Years to 85 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- Lincoln, Nebraska • Omaha, Nebraska
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- Conditions
- Periodontitis
- Interventions
- Minocycline HCL Microspheres
- Drug
- Lead sponsor
- OraPharma
- Industry
- Eligibility
- 30 Years to 65 Years
- Enrollment
- 128 participants
- Timeline
- Started 2004
- U.S. locations
- 5
- States / cities
- Los Angeles, California • Baltimore, Maryland • Boston, Massachusetts + 2 more
- Conditions
- Periodontitis
- Interventions
- scaling and root planing, local tetracycline, systemic metronidazole and amoxicillin, surgery, local antibiotics and systemic metronidazole and amoxicillin, local tetracycline and periodontal surgery, periodontal surgery and systemic metronidazole and amoxicillin, surgery, local tetracycline, systemic metronidazole and amoxicillin
- Other · Drug
- Lead sponsor
- The Forsyth Institute
- Other
- Eligibility
- 20 Years and older
- Enrollment
- 187 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2004
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts