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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:11 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 49–72 of 137 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Mood Management Clear all

Conditions: Major Depressive Disorder
Interventions: ALKS 5461, Placebo; Drug
Lead sponsor: Alkermes, Inc.; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 32 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011
U.S. locations: 2
States / cities: St. Petersburg, Florida • Atlanta, Georgia

Conditions: Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Alcohol Dependence
Interventions: Usual CM, High-Magnitude CM, Shaping CM; Behavioral
Lead sponsor: Washington State University; Other
Eligibility: 18 Years to 65 Years
Enrollment: 392 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2024
U.S. locations: 2
States / cities: Seattle, Washington • Spokane, Washington

Conditions: Type 2 Diabetes, Major Depressive Disorder
Interventions: Diabetes and depression intervention, Diabetes intervention; Behavioral
Lead sponsor: University of Texas Southwestern Medical Center; Other
Eligibility: 21 Years to 70 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: Other Chronic Postoperative Pain
Interventions: Duramorph 150, Acetaminophen, Duramorph 300; Drug
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 69 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Winston-Salem, North Carolina

Conditions: Type 2 Diabetes Mellitus, Serious Mental Illness, Schizophrenia, Major Depression, Bipolar Disorder
Interventions: Lifestyle MIND; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Schizophrenia, Bipolar Disorder, Anosognosia
Interventions: Contingency Management; Behavioral
Lead sponsor: Laureate Institute for Brain Research, Inc.; Other
Eligibility: 18 Years to 65 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Tulsa, Oklahoma

Conditions: Cigarette Smoking-Related Carcinoma
Interventions: Smartphone app-based Intervention (Actify! A app), Smartphone app-based Intervention (Actify! B app), Health Promotion and Education, Survey Administration; Behavioral · Other
Lead sponsor: Fred Hutchinson Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 1,812 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Rheumatoid Arthritis (RA
Interventions: Peer Coach, Healthy Horizons; Behavioral
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 250 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: New York, New York

Conditions: Mood (Psychological Function)
Interventions: Relora, Placebo; Dietary Supplement
Lead sponsor: InterHealth Nutraceuticals, Inc.; Industry
Eligibility: 21 Years to 59 Years
Enrollment: 36 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2016
U.S. locations: 1
States / cities: Boca Raton, Florida

Conditions: Bipolar Disorder
Interventions: Group Psychotherapy; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 75 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Bipolar Disorder
Interventions: Disease Management; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2007
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depressive Disorder
Interventions: LY03005, Pristiq; Drug
Lead sponsor: Luye Pharma Group Ltd.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2017
U.S. locations: 1
States / cities: Eatontown, New Jersey

Conditions: Cigarette Smoking
Interventions: Mood Management Phone Counseling for Smoking Cessation; Behavioral
Lead sponsor: Butler Hospital; Other
Eligibility: 18 Years to 65 Years
Enrollment: 53 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2007 – 2008
U.S. locations: 1
States / cities: Providence, Rhode Island

Conditions: Treatment Resistant Depression (TRD)
Interventions: Ketamine (0.25 mg/kg), Ketamine (0.5 mg/kg), Ketamine (0.75 mg/kg); Drug
Lead sponsor: Soterix Medical; Industry
Eligibility: 18 Years to 59 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 1
States / cities: New York, New York

Conditions: Major Depressive Disorder
Interventions: Not listed
Lead sponsor: Neuronetics; Other
Eligibility: Not listed
Enrollment: 307 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 44
States / cities: Phoenix, Arizona • Berkeley, California • Beverly Hills, California + 38 more

Conditions: Smoking Cessation, Mood Tolerance, Mood Management, Nicotine Replacement Therapy
Interventions: Mood Tolearance, Mood Management, Nicotine Replacement therapy; Behavioral · Drug
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Enrollment: 128 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2003 – 2006
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Depression
Interventions: Care Management for Postpartum Depression, TAU; Behavioral
Lead sponsor: University of Pittsburgh; Other
Eligibility: 18 Years and older · Female only
Enrollment: 628 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2012
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Major Depression, Posttraumatic Stress Disorders, Anxiety Disorders
Interventions: telephone care; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 324 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2003 – 2008
U.S. locations: 1
States / cities: White River Junction, Vermont

Conditions: Depression, Sleep, Stress, Anxiety, Mood Disorders
Interventions: Probiotic; Dietary Supplement
Lead sponsor: Lindenwood University; Other
Eligibility: 18 Years to 50 Years
Enrollment: 70 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Saint Charles, Missouri

Conditions: Bipolar Disorder, Depression
Interventions: Chronic Care Model for Mood Disorders; Behavioral
Lead sponsor: University of Michigan; Other
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2010 – 2012
U.S. locations: 4
States / cities: Palo Alto, California • San Francisco, California • Denver, Colorado + 1 more

Conditions: Treatment Resistant Depression, Major Depressive Disorder, Analgesia, Ketamine, Peripheral Nervous System Agents, Central Nervous System Depressants, Neurotransmitter Agents, Anti-Inflammatory Agents, Physiological Effects of Drugs, Sensory System Agents, Analgesics, Non-Narcotic, Anti-Inflammatory Agents, Non-Steroidal, Depressive Symptoms
Interventions: VTS-K; Drug
Lead sponsor: Theresa Jacob, PhD, MPH; Other
Eligibility: 18 Years to 89 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2024
U.S. locations: 1
States / cities: Brooklyn, New York

Conditions: Treatment Resistant Depression
Interventions: Intranasal esketamine; Drug
Lead sponsor: Psych Atlanta; Other
Eligibility: 18 Years and older
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Marietta, Georgia

Conditions: Bipolar Depression
Interventions: PF-04455242, Placebo; Drug
Lead sponsor: Pfizer; Industry
Eligibility: 18 Years to 55 Years
Enrollment: 18 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2009
U.S. locations: 1
States / cities: New Haven, Connecticut

Conditions: Engagement, Patient, Quality of Life, Mood, Aging Well, Cognitive Change, Mild Cognitive Impairment, Cognitive Impairment, Dementia
Interventions: Behavioral Interventions, Robot Interventions; Behavioral
Lead sponsor: SimpleC, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 63 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2023
U.S. locations: 2
States / cities: Athens, Georgia • Atlanta, Georgia

Search by objective public record fields.

ALK33BUP-201: Safety and Tolerability Study of ALKS 33-BUP (ALKS 5461) Administration in Subjects With MDD

Individualizing Incentives for Alcohol in the Severely Mentally Ill

A Comprehensive Intervention for Diabetes and Comorbid Depression in Primary Care

High Pain Intervention in Cesarean Sections

Lifestyle MIND- Feasibility of Wait-list Control

Contingency Management for Problematic Behavior Reduction in the Community

A Behavioral Application for Improving Smoking Cessation Among Smokers

Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being

Effect of Relora Supplement on Anxiety, Cognitive Performance & Mood Tested After Induced Stress

A Pilot Study of Psychodynamic Psychotherapy for Bipolar Disorder

Improving Care for Patients With Bipolar Disorder

Relative Bioavailability (RBA) Study of LY03005 vs Pristiq®

Mood Management Phone Counseling in Smoking Cessation

Ketamine Biomarker Validation

NeuroStar TMS Therapy System: Utilization and Outcomes

Mood and Smoking: A Comparison of Smoking Cessation Treatments

Identification and Therapy of Postpartum Depression

Telephone Care as a Substitute for Routine Psychiatric Medication

Probiotic Administration on Mood

Disseminating Evidence-based Mood Disorder Chronic Care Models

Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression

Intranasal Esketamine to Maintain the Antidepressant Response to IV Racemic Ketamine

A First In Human Study To Evaluate The Safety, Tolerability And Pharmacokinetics Of PF-04455242 In Single Rising Doses In Healthy Adult Volunteers

SimpleC Wellness Platform With Social Robot Interaction (Long-term)