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ClinicalTrials.gov public records Last synced Nov 15, 2026, 2:27 PM EST

All trial information on this site comes from the official ClinicalTrials.gov public API (clinicaltrials.gov/api/v2), run by the U.S. National Library of Medicine. We only display that public information; we do not add opinions, endorsements, or any other intent. Always review the official ClinicalTrials.gov record for the latest information.

Showing 97–120 of 137 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Mood Management Clear all

Conditions: Major Depressive Disorder
Interventions: LY03005; Drug
Lead sponsor: Luye Pharma Group Ltd.; Industry
Eligibility: 18 Years to 50 Years
Enrollment: 34 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Longevity, Quality of Life, Mood, Inflammation, Immune Health, Pain Management, Weight Management, Alertness
Interventions: GLP-1, Placebo; Drug
Lead sponsor: AgelessRx; Industry
Eligibility: 18 Years to 65 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2025
U.S. locations: 1
States / cities: Ann Arbor, Michigan

Conditions: Engagement, Patient, Mood, Quality of Life, Aging, Mild Cognitive Impairment, Cognitive Impairment, Dementia
Interventions: SimpleC Wellness Platform with Social Robot Interaction; Other
Lead sponsor: SimpleC, LLC; Industry
Eligibility: 18 Years and older
Enrollment: 26 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022
U.S. locations: 2
States / cities: Athens, Georgia • Atlanta, Georgia

Conditions: Major Depression
Interventions: Eicosapentaenoic acid (EPA) 0.7 grams/day or 1.5 grams/day, Placebo; Drug
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years to 55 Years
Enrollment: 24 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2007
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Substance Withdrawal Syndrome
Interventions: dehydroepiandrosterone (DHEA), pregnenolone, Placebo; Dietary Supplement · Drug
Lead sponsor: Jed E. Rose; Other
Eligibility: 18 Years to 65 Years · Male only
Enrollment: 22 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2011
U.S. locations: 2
States / cities: Durham, North Carolina • Raleigh, North Carolina

Conditions: Schizophrenia, Schizoaffective Disorder, Bipolar Disorder, Depression
Interventions: CBHH+AT, CBHH+SMT, CBHH; Behavioral
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 301 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2021
U.S. locations: 2
States / cities: Boston, Massachusetts • Cambridge, Massachusetts

Conditions: Lung Cancer, Breast Cancer, Prostate Cancer, Multiple Myeloma, Melanoma
Interventions: mHealth Intervention; Behavioral
Lead sponsor: Ohio State University Comprehensive Cancer Center; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2029
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Depression, Depression, Postpartum
Interventions: Standard interpersonal psychotherapy (IPT), Clinician managed interpersonal psychotherapy (CM-IPT); Behavioral
Lead sponsor: University of Iowa; Other
Eligibility: 18 Years and older · Female only
Enrollment: 140 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2001 – 2007
U.S. locations: 1
States / cities: Iowa City, Iowa

Conditions: Major Depressive Disorder
Interventions: Mobile App; Behavioral
Lead sponsor: Wake Forest University Health Sciences; Other
Eligibility: 18 Years to 70 Years
Enrollment: 40 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2019
U.S. locations: 1
States / cities: Oak Lawn, Illinois

Conditions: Mood Disorder, Anxiety Disorders
Interventions: Low dose NPY, High dose NPY, Placebo; Drug
Lead sponsor: Dennis Charney; Other
Eligibility: 25 Years to 45 Years · Male only
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2012
U.S. locations: 1
States / cities: New York, New York

Conditions: Multiple Sclerosis
Interventions: Activity Monitoring and Symptom Coaching, Passive Activity Monitoring; Other
Lead sponsor: University of California, San Francisco; Other
Eligibility: 18 Years and older
Enrollment: 30 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: San Francisco, California

Conditions: Depressive Disorder, Major, Unipolar Depression
Interventions: Deep Brain Stimulation, Libra Deep Brain Stimulation System; Device
Lead sponsor: Abbott Medical Devices; Industry
Eligibility: 21 Years to 70 Years
Enrollment: 125 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2015
U.S. locations: 11
States / cities: Stanford, California • Chicago, Illinois • Worcester, Massachusetts + 8 more

Conditions: Depressive Disorder, Major, Bipolar Disorder, Schizo Affective Disorder, Schizophrenia
Interventions: CAT, R-CAT; Behavioral
Lead sponsor: The University of Texas Health Science Center at San Antonio; Other
Eligibility: 18 Years to 65 Years
Enrollment: 56 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2022
U.S. locations: 1
States / cities: San Antonio, Texas

Conditions: Emotional Distress
Interventions: Mood tracker ratings; Behavioral
Lead sponsor: Memorial Hermann Health System; Other
Eligibility: 18 Years to 62 Years
Enrollment: 126 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Houston, Texas

Conditions: Mood Disorders, Substance-Related Disorders
Interventions: Facilitate evidence-based treatment for depression; Procedure
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: Not listed
Enrollment: 300 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2004 – 2006
U.S. locations: 5
States / cities: No. Little Rock, Arkansas • New Orleans, Louisiana • Biloxi, Mississippi + 2 more

Conditions: Major Depressive Disorder
Interventions: Escitalopram, Placebo; Drug
Lead sponsor: New York State Psychiatric Institute; Other
Eligibility: 18 Years to 60 Years
Enrollment: 3 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Pharmacogenetics, Depressive Disorder, Major, Medication Therapy Management
Interventions: Pharmacogenomic Screening; Other
Lead sponsor: Auburn University; Other
Eligibility: 19 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2022
U.S. locations: 1
States / cities: Tuscaloosa, Alabama

Conditions: Schizophrenia, Psychotic Disorders, Substance-Related Disorders, Bipolar Disorder
Interventions: Time limited case management, Health Education; Behavioral
Lead sponsor: US Department of Veterans Affairs; Federal
Eligibility: 18 Years and older
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2009
U.S. locations: 2
States / cities: Bedford, Massachusetts • East Orange, New Jersey

Conditions: Major Depressive Disorder, Anxiety Disorders
Interventions: Hydrocortisone; Drug
Lead sponsor: University of Texas at Austin; Other
Eligibility: 18 Years and older
Enrollment: 120 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2014
U.S. locations: 2
States / cities: Austin, Texas

Conditions: Depressive Disorders, Alcohol Use Disorders, Post-traumatic Stress Disorder (PTSD)
Interventions: Usual Care, Blended Telemedicine-Based Integrated Care; Other
Lead sponsor: VA Office of Research and Development; Federal
Eligibility: 18 Years and older
Enrollment: 318 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2020
U.S. locations: 1
States / cities: North Little Rock, Arkansas

Conditions: Alcohol Abuse, Schizophrenia, Bipolar Disorder, Major Depressive Disorder
Interventions: Contingency Management; Behavioral
Lead sponsor: University of Washington; Other
Eligibility: 18 Years to 65 Years
Enrollment: 123 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Seattle, Washington

Conditions: Postpartum Depression
Interventions: Screening and follow up, Usual care; Behavioral
Lead sponsor: Olmsted Medical Center; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 3,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2010
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Breakthrough Bleeding, Breakthrough Spotting
Interventions: remove ring if bleeding or spotting occurs more than 5 days, If bleeding does not remove ring; Other
Lead sponsor: Scott and White Hospital & Clinic; Other
Eligibility: 18 Years to 45 Years · Female only
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2006 – 2008
U.S. locations: 1
States / cities: Temple, Texas

Conditions: Anxiety, Depression, Mood
Interventions: Improvisation + Wellness, Improvisation, Social Craft; Behavioral
Lead sponsor: Case Western Reserve University; Other
Eligibility: 8 Years to 17 Years
Enrollment: 110 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2027
U.S. locations: 1
States / cities: Cleveland, Ohio

Search by objective public record fields.

A Relative Bioavailability Food Effect Study of LY03005

Effectiveness of Microdosed GLP-1 in Improving Health, Quality of Life, and Longevity Measures

SimpleC Wellness Platform With Social Robot Interaction

Essential Fatty Acids for Major Depression

The Effects of One-Time Pregnenolone, Dehydroepiandrosterone (DHEA), or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers

Self-Management Training and Automated Telehealth to Improve SMI Health Outcomes

Telemedicine-mHealth Symptom Cluster Intervention for Advanced Cancer Patients: Finding Our Center Under Stress (FOCUS)

Clinician Managed Interpersonal Psychotherapy

Patient Management of Depression Through Technology: a Study of Digitally Enabled Engagement

Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers

Coaching and Activity Tracking in Multiple Sclerosis - A Pilot Study

Deep Brain Stimulation for Major Depressive Disorder

In-person vs. Remote Wellness Support

Mood Tracker Smartphone App for Management of Emotional Distress After TBI

Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs

Developing New Clinical Management Strategies

Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans

A Brief Community Linkage Intervention for Dually Diagnosed Individuals

Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration

Implementing a Blended Care Model That Integrates Mental Healthcare and Primary Care Using Telemedicine and Care Management for Patients With Depression or Alcohol Use Disorder in Small Primary Care Clinics

Contingency Management of Alcohol Abuse in the Severely Mentally ILL

Translating Research Into Practice for Postpartum Depression

Management of Breakthrough Bleeding During Extended Therapy Use With NuvaRing®

Developing Resilience and Anxiety Management Through the Arts