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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Moral Injury Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Better Together Physician Coaching to Mitigate Burnout Amongst Clinicians

NCT05635448
View directory record Official record
Conditions
Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome, Moral Injury, Loneliness
Interventions
Better Together Physician Coaching Program, No intervention - waitlist control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 99 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 3, 2024 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Pilot Study Testing a Web-Based Moral Elevation Intervention for Veterans With PTSD and Moral Injury

NCT03906240
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Moral Injury
Interventions
Moral Elevation intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
87 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Jul 23, 2026, 4:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Moral Injury Symptom Scale/Moral Injury Outcome Scale

NCT04261751
View directory record Official record
Conditions
Moral Injury, Anxiety, Depression, Burn-Out
Interventions
Clinician Questionnaire
Other
Lead sponsor
AdventHealth
Other
Eligibility
18 Years and older
Enrollment
483 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Oct 5, 2023 · Synced Jul 23, 2026, 4:14 AM EDT
Recruiting Not applicable Interventional

Mental Health Clinician / Chaplain Collaboration

NCT07579143
View directory record Official record
Conditions
Moral Injury
Interventions
facilitate forgiveness and community connection to address symptoms of moral injury
Behavioral
Lead sponsor
Central Arkansas Veterans Healthcare System
Federal
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Little Rock, Arkansas • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 10, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans

NCT03760731
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 89 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 28, 2025 · Synced Jul 23, 2026, 4:14 AM EDT
Not yet recruiting Not applicable Interventional

Comparing Two Moral Injury Treatments

NCT07710521
View directory record Official record
Conditions
Moral Injury
Interventions
Acceptance and Commitment Therapy for Moral Injury (ACT-MI), Present Centered Therapy for Moral Injury (PCT-MI)
Behavioral
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 89 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 16, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Phase 3 Interventional Results available

Frontline Clinician Psilocybin Study

NCT05163496
View directory record Official record
Conditions
Burnout, Caregiver, Burnout, Professional, COVID-19, Depression, Post Traumatic Stress Disorder, Moral Injury
Interventions
Psilocybin (Usona Institute), Active placebo
Drug
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Better Together: an Online Physician Coaching Program for Medical Trainees

NCT05280964
View directory record Official record
Conditions
Burnout, Self-compassion, Moral Injury, Impostor Phenomenon
Interventions
Better Together Physician Coaching
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 9, 2023 · Synced Jul 23, 2026, 4:14 AM EDT
Enrolling by invitation Not applicable Interventional

Implementation of Innovative Treatment for Moral Injury Syndrome: A Hybrid Type 2 Study

NCT06230887
View directory record Official record
Conditions
Moral Injury Syndrome
Interventions
Building Spiritual Strength, Present Centered Group Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
5
States / cities
Little Rock, Arkansas • Decatur, Georgia • Augusta, Maine + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Recruiting No phase listed Observational

Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospective Case Series

NCT07473505
View directory record Official record
Conditions
PTSD, Trauma-related Mental Health Symptoms, Moral Injury, Anxiety, Traumatic Brain Injury
Interventions
stellate ganglion block with 0.5% ropivacaine
Procedure
Lead sponsor
Reset Medical and Wellness Center
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Strongsville, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Enrolling by invitation No phase listed Observational

A Study of Moral Distress, Moral Injury and Post-Traumatic Stress for Nurses

NCT07455370
View directory record Official record
Conditions
Moral Injury, Moral Distress, Post-Traumatic Stress, Nurse Well-being, Wellbeing, Wellness, Psychological, Wellness, Nurses, Nurse Health
Interventions
Surveys
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
Not listed
Enrollment
21,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
3
States / cities
Phoenix, Arizona • Jacksonville, Florida • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Active, not recruiting Not applicable Interventional

Consulting After Combat: Interviewing Veterans to Develop a Therapy to Restore Functioning and Reintegration After Moral Injury Events

NCT05020587
View directory record Official record
Conditions
Moral Injury, Functional Impairment
Interventions
Open pilot trial of a group therapy manual.
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Mindful Self Compassion for Combat Deployed Veterans With Moral Injury and Co-occurring PTSD-SUD

NCT03681288
View directory record Official record
Conditions
Substance Use Disorder, Post-traumatic Stress Disorder, Moral Injury
Interventions
Mindful Self-Compassion
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 20, 2024 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Adaptation of Mindfulness Training to Treat Moral Injury in Veterans

NCT05341882
View directory record Official record
Conditions
Mindfulness, Educational Support
Interventions
Mindfulness, Educational Support
Behavioral
Lead sponsor
Old Dominion University
Other
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Norfolk, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2023 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional

Perioperative Outcome Risk Assessment With Computer Learning Enhancement

NCT05042804
View directory record Official record
Conditions
Morality, Acute Kidney Injury
Interventions
Machine learning models predicting postoperative death and acute kidney injury
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
5,114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 13, 2022 · Synced Jul 23, 2026, 4:14 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to Occupational Trauma

NCT04626050
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Moral Injury
Interventions
Medical Music, Narrative Writing, Prolonged Exposure Therapy, Interpersonal Psychotherapy
Behavioral
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Not yet recruiting Not applicable Interventional

A Randomized Controlled Trial of a Web-Based Moral Elevation Intervention for Veterans With PTSD

NCT06788678
View directory record Official record
Conditions
Posttraumatic Stress Disorder
Interventions
MOVED, Supportive Care Control
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Wellness Intervention for Nurses Post Traumatic Growth and Selfcare

NCT06674876
View directory record Official record
Conditions
Trauma, Psychological, Moral Injury, Compassion Fatigue
Interventions
Blog writing
Behavioral
Lead sponsor
Purdue University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Nov 4, 2024 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Better Together Physician Coaching to Mitigate Burnout in Male-Identifying Trainees

NCT05550753
View directory record Official record
Conditions
Burnout, Professional, Self Compassion, Flourishing, Imposter Syndrome, Moral Injury
Interventions
Better Together Physician Coaching Program, No intervention - placebo control
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
Male only
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 27, 2023 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

A Novel Posttraumatic Stress Disorder Treatment for Veterans With Moral Injury

NCT03764033
View directory record Official record
Conditions
Moral Injury
Interventions
Impact of Killing (IOK), Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 82 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
3
States / cities
San Francisco, California • The Bronx, New York • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Jul 23, 2026, 4:14 AM EDT
Active, not recruiting Not applicable Interventional

Non-Inferiority Trial of TrIGR for PTSD

NCT05789329
View directory record Official record
Conditions
PTSD
Interventions
Trauma Informed Guilt Reduction Therapy, Cognitive Processing Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
San Diego, California • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Jun 28, 2026 · Synced Jul 23, 2026, 4:14 AM EDT
Completed Not applicable Interventional Results available

Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure

NCT03056157
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Moral Injury, Traumatic Loss
Interventions
Adaptive Disclosure for Moral Injury and Loss, Present Centered Therapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
174 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
5
States / cities
San Diego, California • San Francisco, California • Boston, Massachusetts + 2 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2024 · Synced Jul 23, 2026, 4:14 AM EDT