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Showing 1–24 of 244 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Morbid Obesity Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Investigating the Link Between Type 2 Immunity and NAFLD in Human Obesity

NCT04232566
View directory record Official record
Conditions
Obesity, Morbid, NASH - Nonalcoholic Steatohepatitis, Chronic Inflammation
Interventions
Bariatric surgery
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 70 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 21, 2026, 7:10 AM EDT
Enrolling by invitation No phase listed Observational

Endoscopic Metabolic and Bariatric Therapies

NCT05725967
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity Associated Disorder, Bariatric Surgery Candidate, Fistula, Gastric, Roux-en-y Anastomosis Site, Ulcer, Gastric, Abdominal Pain, Abdominal Obesity, Complication of Surgical Procedure, Complication of Treatment, Complication,Postoperative, Weight Gain, Weight Loss, Leak, Anastomotic, Delayed Gastric Emptying Following Procedure
Interventions
Primary Obesity Endoscopic Procedures, Endoscopic Revision of Bariatric Surgical Procedures, Bariatric Surgery Procedures, Endoscopic Sleeve Gastroplasty, Trans-oral Outlet Reduction, Intragastric Balloon, Primary obesity surgery endoluminal, Restorative obesity surgery endoluminal, Argon Plasma Coagulation, Gastroplasty with Endoscopic Myotomy, Bariatric Endoscopic Antral Myotomy, Pylorus Sparing Antral Myotomy, Aspiration Therapy
Procedure · Device
Lead sponsor
Christopher C. Thompson, MD, MSc
Other
Eligibility
18 Years to 80 Years
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Lifestyle Intervention Feasibility for Arrhythmia and Symptoms With Intermittent Fasting (LIFE AS IF)

NCT04090840
View directory record Official record
Conditions
Obesity, Morbid Obesity, Diabetes Mellitus, Type 2, Atrial Fibrillation
Interventions
Intermittent Fasting
Behavioral
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated May 5, 2024 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Results available

Effectiveness and Safety Study of LAP-BAND Treatment for Obese Adolescents

NCT00447590
View directory record Official record
Conditions
Morbid Obesity
Interventions
LAP-BAND System
Device
Lead sponsor
Apollo Endosurgery, Inc.
Industry
Eligibility
14 Years to 17 Years
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2013
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2014 · Synced Jul 21, 2026, 7:10 AM EDT
Withdrawn No phase listed Observational

Bariatric Surgery Outcomes

NCT01057784
View directory record Official record
Conditions
Morbid Obesity
Interventions
Bariatric surgery.
Procedure
Lead sponsor
University of California, Los Angeles
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 7, 2014 · Synced Jul 21, 2026, 7:10 AM EDT
Terminated Not applicable Interventional Results available

Use of Negative Pressure Wound Therapy in Morbidly Obese Women After Cesarean Delivery

NCT03269968
View directory record Official record
Conditions
Obesity, Morbid, Wound Infection, Wound Complication
Interventions
Negative pressure wound therapy (PREVENA Incision Management Therapy System), Standard dressing
Device
Lead sponsor
Medstar Health Research Institute
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 18, 2020 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Effectiveness of Behavioral Treatments for Obesity and Major Depression in Women

NCT00572520
View directory record Official record
Conditions
Depression, Obesity
Interventions
Weight loss treatment, Behavior therapy for depression, Health education counseling
Behavioral
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
21 Years to 65 Years · Female only
Enrollment
161 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 4, 2018 · Synced Jul 21, 2026, 7:10 AM EDT
Terminated Phase 3 Interventional Results available

Effect of Subcutaneous Semaglutide on Kidney Transplant Candidacy

NCT04741074
View directory record Official record
Conditions
CKD, Diabetic Kidney Disease, Type 2 Diabetes Mellitus in Obese, Obesity, Severe Obesity
Interventions
Semaglutide 2 mg/1.5 ml (1.34 mg/ml), prefilled pen-injector for subcutaneous injection solution, Placebo 1.5 ml, prefilled pen-injector for subcutaneous injection solution
Drug
Lead sponsor
Geisinger Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
Danville, Pennsylvania • Wilkes-Barre, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 8, 2024 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Results available

Comparison of Staples Versus Subcuticular Suture in Class III Obese Women Undergoing Cesarean Delivery

NCT02466776
View directory record Official record
Conditions
Obesity, Severe, Cesarean Section
Interventions
Absorbable subcuticular suture, Stainless steel staples
Device
Lead sponsor
MemorialCare Health System
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
238 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
4
States / cities
Long Beach, California • Orange, California
Source: ClinicalTrials.gov public record
Updated Jan 8, 2024 · Synced Jul 21, 2026, 7:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study to Determine Incidence of Hypoventilation in Patients Who Have Undergone Gastric Bypass

NCT00316446
View directory record Official record
Conditions
Morbid Obesity, Bariatric Surgery
Interventions
Not listed
Lead sponsor
University of South Florida
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2009
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Sep 19, 2012 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Feasibility and Preliminary Efficacy of Support Figure Attendance at Bariatric Patients' Clinical Visits

NCT03642197
View directory record Official record
Conditions
Obesity, Morbid, Bariatric Surgery Candidate, Diet Habit, Behavior, Social, Physical Activity
Interventions
Attendance
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jul 21, 2026, 7:10 AM EDT
Recruiting No phase listed Observational

Gut Microbiota in Metabolic Surgery

NCT05000996
View directory record Official record
Conditions
Bariatric Surgery Candidate, Cardiovascular Diseases, Type 2 Diabetes, Dyslipidemias, Hypertension, Morbid Obesity
Interventions
Bariatric Surgery
Procedure
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
21 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2035
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 3, 2025 · Synced Jul 21, 2026, 7:10 AM EDT
Enrolling by invitation No phase listed Observational

Cognitive Impairment, Obesity, and the Effects of Bariatric Surgery

NCT05215886
View directory record Official record
Conditions
Obesity, Morbid, Bariatric Surgery Candidate
Interventions
Surgery
Behavioral
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 75 Years
Enrollment
9,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 21, 2026, 7:10 AM EDT
Terminated No phase listed Observational

Prospective Case-Series of Ligasure Advance Pistol Grip and LigaSure Blunt Tip

NCT01759550
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Jul 21, 2026, 7:10 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Time-restricted Eating Among Pregnant Females With Severe Obesity

NCT06477120
View directory record Official record
Conditions
Obesity, Morbid, Time Restricted Eating, Pregnancy Weight Gain
Interventions
Time Restricted Eating
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jan 22, 2026 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Endoscopic Gastric Mucosal Devitalization (GMD) as a Primary Obesity Therapy - Part 2

NCT03638843
View directory record Official record
Conditions
Obesity, Obesity, Morbid, Obesity; Endocrine, Bariatric Surgery Candidate
Interventions
Gastric mucosal devitalization
Procedure
Lead sponsor
Johns Hopkins University
Other
Eligibility
28 Years to 60 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 19, 2021 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bariatric Embolization of Arteries With Imaging Visible Embolics (BEATLES)

NCT04197336
View directory record Official record
Conditions
Obesity, Morbid Obesity, Weight Loss
Interventions
Bariatric Embolization of Arteries with imaging visible Embolics
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 16, 2025 · Synced Jul 21, 2026, 7:10 AM EDT
Completed No phase listed Observational

A Protein-sparing Modified Fast for Children and Adolescents With Severe Obesity (PSMF)

NCT03899311
View directory record Official record
Conditions
Obesity, Childhood
Interventions
protein-sparing modified fast diet
Other
Lead sponsor
Ihuoma Eneli
Other
Eligibility
11 Years to 19 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 1, 2019 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional

Connect for Health Pediatric Weight Management Program

NCT04042493
View directory record Official record
Conditions
Overweight and Obesity, Severe Obesity
Interventions
Connect for Health
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
2 Years to 12 Years
Enrollment
19,304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
3
States / cities
Denver, Colorado • Boston, Massachusetts • Greenville, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Results available

Evaluation of Endostapled Anastomoses for Laparoscopic Gastric Bypass (EEA-LGB)

NCT00254072
View directory record Official record
Conditions
Morbid Obesity
Interventions
3.5 mm vs 4.8 mm Stapler During Laparoscopic Gastric Bypass
Procedure
Lead sponsor
University of California, Irvine
Other
Eligibility
18 Years to 60 Years
Enrollment
355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
6
States / cities
Orange, California • Tampa, Florida • Boston, Massachusetts + 3 more
Source: ClinicalTrials.gov public record
Updated Feb 17, 2010 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional

The Peds Obesity Study

NCT02353637
View directory record Official record
Conditions
Pediatric Obesity
Interventions
Partial Meal Replacements
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
12 Years to 17 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 18, 2018 · Synced Jul 21, 2026, 7:10 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Adherence to Walking on an Alter G Anti-Gravity Treadmill

NCT03690752
View directory record Official record
Conditions
Severe Obesity
Interventions
unweighting using Alter-G Anti-Gravity Treadmill, normal weight using Alter-G Anti-Gravity Treadmill
Device
Lead sponsor
Texas Tech University
Other
Eligibility
20 Years to 55 Years
Enrollment
26 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Oct 17, 2018 · Synced Jul 21, 2026, 7:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Obstructive Sleep Apnea in Pregnancy

NCT02383706
View directory record Official record
Conditions
Sleep Apnea, Obstructive, Pregnancy, Obesity, Morbid
Interventions
ApneaLink Air, Berlin Quesionnaire, Epworth Sleepiness Scale, STOP-BANG questionnaire, Physical exam
Device · Behavioral · Other
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
108 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 18, 2019 · Synced Jul 21, 2026, 7:10 AM EDT
Completed No phase listed Observational

Bariatric Surgery and Skeletal Health

NCT01098942
View directory record Official record
Conditions
Morbid Obesity
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Jul 21, 2026, 7:10 AM EDT