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Showing 1–22 of 22 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mother-Child Interaction Clear all
Completed No phase listed Observational

The Influence of Maternal Age, Employment Status, and Parenthood Status on Children's Cognitive Development

NCT00361829
View directory record Official record
Conditions
Child Development
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
5 Months to 23 Years
Enrollment
2,355 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1988
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Collaborative Perinatal Mental Health and Parenting Support in Primary Care

NCT02724774
View directory record Official record
Conditions
Parenting, Mother-child Relations
Interventions
Promoting First Relationships®
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Jul 22, 2026, 12:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

NCT02158338
View directory record Official record
Conditions
Asthma in Children, Anxiety
Interventions
Asthma, Non-asthma
Other
Lead sponsor
Ran Anbar
Other
Eligibility
Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Depressed Low Income Mothers and Their Infants

NCT00105573
View directory record Official record
Conditions
Depression
Interventions
Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Phase 2 Interventional

Relational Parenting Group for Opioid-addicted Mothers

NCT00319241
View directory record Official record
Conditions
Substance Abuse, Child Abuse
Interventions
Parenting Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months

NCT03334266
View directory record Official record
Conditions
Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits, Breast Feeding, Physical Activity, Childhood Obesity, Feeding Behavior
Interventions
Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years to 24 Years · Female only
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
3
States / cities
Fort Defiance, Arizona • Whiteriver, Arizona • Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Jul 22, 2026, 12:03 PM EDT
Withdrawn Not applicable Interventional

Project BELONG: Breaking the Cycle of Intergenerational Family Violence and Trauma

NCT03212339
View directory record Official record
Conditions
Mother-child Relations, Parenting, Parent Child Abuse, Family Conflict, Parental Stress, Family Relations, Childhood Disorder of Social Functioning, Unspecified
Interventions
Therapeutic intervention
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older · Female only
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 4, 2019 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
View directory record Official record
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 12, 2025 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurobehavioral Effects of Prenatal Mindfulness Training on Maternal Presence and Compassionate Love

NCT05241600
View directory record Official record
Conditions
Maternal-Fetal Relations, Mother-Child Relations, Maternal Behavior
Interventions
Mindfulness-Based Childbirth and Parenting, Non-Mindfulness-Based Childbirth Class
Behavioral
Lead sponsor
Heidemarie Laurent
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
2
States / cities
Champaign, Illinois • University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 1, 2025 · Synced Jul 22, 2026, 12:03 PM EDT
Recruiting No phase listed Observational

Boston Birth Cohort Study

NCT03228875
View directory record Official record
Conditions
Maternal Health, Child Health, Pregnancy Complications, Birth Outcome, Adverse
Interventions
Not listed
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
0 Years to 50 Years
Enrollment
24,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Parenting Intervention for Mothers With Substance Use Disorder

NCT06489522
View directory record Official record
Conditions
Substance Use Disorders, Children of Mothers With Substance Use Disorders
Interventions
THRIVE
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
3 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 22, 2026, 12:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Evaluation Study of the Impact of the New Brain Builders Parenting Class

NCT03866616
View directory record Official record
Conditions
Child Development, Mother-Child Interaction
Interventions
Brain Builders Parenting Class, Control (Usual care)
Behavioral
Lead sponsor
William Marsh Rice University
Other
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 11, 2020 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mother-infant Bonding During COVID-19

NCT04531618
View directory record Official record
Conditions
Child Development, Mother-Infant Interaction, Relation, Parent-Child
Interventions
Emotional Exchange (EE), Newborn Care (NC)
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
12 Hours to 72 Hours
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Results available

Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

NCT00319436
View directory record Official record
Conditions
Maternal Substance Use, Child Abuse and Neglect
Interventions
Mentalizing Therapy for Substance Using Mothers, Standard Parent Education for Substance Using Mothers
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 8, 2020 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers

NCT01240993
View directory record Official record
Conditions
Parenting Capacities of Substance Abusing Mothers
Interventions
Mothers and Toddlers Program, Parent Education
Behavioral
Lead sponsor
Yale University
Other
Eligibility
21 Years to 45 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut • West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Apr 1, 2020 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piloting a Precision Approach to Home Visiting

NCT03975530
View directory record Official record
Conditions
Parenting, Mother-Child Relations, Child Development
Interventions
Precision Family Spirit, Standard Family Spirit
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Sault Ste. Marie, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Impact Evaluation of MotherWise Program

NCT02792309
View directory record Official record
Conditions
Parenting, Family Relations, Marriage, Mother-Child Relations
Interventions
MotherWise Program
Behavioral
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
953 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development

NCT05400161
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations, Child Development
Interventions
MoodGym, Social Media-Based Parenting Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 1: Long-term Follow-up

NCT05424471
View directory record Official record
Conditions
Obesity, Water; Lack of, Childhood Obesity, Feeding Behavior, Mother-Child Relations, Dietary Habits
Interventions
Family Spirit Nurture (FSN), Control Group - Vehicle Safety
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Jul 22, 2026, 12:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 Months

NCT03101943
View directory record Official record
Conditions
Obesity, Water; Lack of, Breast Feeding, Tooth Erosion, Dental Plaque, Infant Obesity, Feeding Behavior, Mother-Child Relations, Dietary Habits, Dental Caries
Interventions
Family Spirit Nurture (FSN), Control Program, Water Delivery
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years and older · Female only
Enrollment
136 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 10, 2020 · Synced Jul 22, 2026, 12:03 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Clinical Interventions to Mitigate Neurodevelopmental Risk

NCT04233489
View directory record Official record
Conditions
Child Development, Mother-Infant Interaction, Diabetes Mellitus, Gestational
Interventions
Family Nurture Intervention (FNI)
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
12 Hours to 3 Days
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 12, 2022 · Synced Jul 22, 2026, 12:03 PM EDT