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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mother-Child Relations Clear all
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent Encouragement And Coaching of Happiness in Youth

NCT06725160
View directory record Official record
Conditions
Depression, Parent-Child Relations
Interventions
Parent Coaching, Active Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
4 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Maternal Cancer Diagnosis and Treatment During Pregnancy:a Database for Maternal, Fetal, and Neonatal Outcomes

NCT02749474
View directory record Official record
Conditions
Pregnancy, Cancer, Cancer in Pregnancy, Gestational Breast Cancer, Pregnancy Related
Interventions
Not listed
Lead sponsor
The Cooper Health System
Other
Eligibility
Female only
Enrollment
400 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jun 9, 2024 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development

NCT05400161
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations, Child Development
Interventions
MoodGym, Social Media-Based Parenting Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Phase 1 Interventional

Integrating Interventions for Maternal Substance Abuse

NCT01188434
View directory record Official record
Conditions
Substance Abuse, Child Neglect
Interventions
ITSAN, Services as Usual
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
Female only
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2012
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 28, 2015 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of an Evidence-Based Parenting Service on Maternal Sensitivity and Infant Cellular Aging in a Population of Under-Resourced Families

NCT06740266
View directory record Official record
Conditions
Parent Child Relationship, Child Social-Emotional Development, Telomere Length, Epigenetic Aging
Interventions
Promoting First Relationships in Primary Care (PFR-PC)
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older · Female only
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 5, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed No phase listed Observational

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

NCT01702922
View directory record Official record
Conditions
Parents of Children With Cancer, Parents of Children With NF1, Parents of Children With Neurofibromatosis Type I
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
262 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2020
U.S. locations
2
States / cities
Bethesda, Maryland • Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 30, 2024 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Intervention for IPV-exposed Pregnant Women

NCT04068662
View directory record Official record
Conditions
Postpartum Depression, Posttraumatic Stress Disorder, Infant Behavior, Violence, Parenting
Interventions
Pregnant Moms' Empowerment Program, Nondirective Support Group
Behavioral
Lead sponsor
University of Notre Dame
Other
Eligibility
3 Months to 55 Years · Female only
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Notre Dame, Indiana • Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mother-infant Bonding During COVID-19

NCT04531618
View directory record Official record
Conditions
Child Development, Mother-Infant Interaction, Relation, Parent-Child
Interventions
Emotional Exchange (EE), Newborn Care (NC)
Behavioral · Other
Lead sponsor
Columbia University
Other
Eligibility
12 Hours to 72 Hours
Enrollment
132 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Piloting a Precision Approach to Home Visiting

NCT03975530
View directory record Official record
Conditions
Parenting, Mother-Child Relations, Child Development
Interventions
Precision Family Spirit, Standard Family Spirit
Behavioral
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years and older · Female only
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Sault Ste. Marie, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 5, 2022 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting No phase listed Observational

Predicting and Preventing Adverse Maternal and Child Outcomes of Opioid Use Disorder in Pregnancy

NCT05942313
View directory record Official record
Conditions
Opioid Use Disorder, Pregnancy Related
Interventions
Buprenorphine/ Methadone exposure
Drug
Lead sponsor
Ilana Hull
Other
Eligibility
18 Years and older · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 5, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Depressed Low Income Mothers and Their Infants

NCT00105573
View directory record Official record
Conditions
Depression
Interventions
Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 2: Family Spirit Nurture, Prenatal - 18 Months

NCT03334266
View directory record Official record
Conditions
Obesity, Infant Obesity, Mother-Child Relations, Dietary Habits, Breast Feeding, Physical Activity, Childhood Obesity, Feeding Behavior
Interventions
Family Spirit Nurture (FSN), Injury Prevention Education (IPE), Optimized Standard Care (OSC)
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
14 Years to 24 Years · Female only
Enrollment
259 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2023
U.S. locations
3
States / cities
Fort Defiance, Arizona • Whiteriver, Arizona • Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Mar 5, 2023 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Child Healthcare at MATER - Pediatric Study

NCT05488379
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Group well child care
Other
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older · Female only
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 22, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Counseling to Reduce Children's SHS Exposure: A Trial With Maternal Smokers

NCT02117947
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Behavioral Counseling, Self-help control
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 14, 2017 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Healthy Moms-Healthy Kids: Reducing Maternal Depression for Better Outcomes in Head Start Children

NCT02145273
View directory record Official record
Conditions
Maternal Depression, Parenting Behavior, Health, Interpersonal Relationships, Goal Directed Behavior, Child Behavior, Child School Readiness
Interventions
Interpersonal Psychotherapy for Depression -Group
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional

Postpartum Intervention for Mothers With Opioid Use Disorders (R33)

NCT07632053
View directory record Official record
Conditions
Opioid Use Disorder, Parent-Child Relations
Interventions
Mom Power
Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Ann Arbor, Michigan • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional

Stage III Community-based Efficacy Trial for Mothering From the Inside Out

NCT02955199
View directory record Official record
Conditions
Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional, Child Abuse, Parenting, Parent-Child Problem, Parent-Child Relations, Parent / Child Problem, Parenteral Drug Abuse, Parents
Interventions
Mothering From the Inside Out (MIO), Parent Education
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 13, 2021 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Phase 2 Interventional

Relational Parenting Group for Opioid-addicted Mothers

NCT00319241
View directory record Official record
Conditions
Substance Abuse, Child Abuse
Interventions
Parenting Intervention
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2003
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 30, 2020 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effects of Maternal Interpretation Biases on Child Anxiety and Related Responses

NCT02095340
View directory record Official record
Conditions
Anxiety Disorders
Interventions
Positive Interpretation Bias Training, Neutral Interpretation Bias Training
Other
Lead sponsor
University of Houston
Other
Eligibility
8 Years to 12 Years
Enrollment
210 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Sep 5, 2026, 5:25 PM EDT
Not listed Not applicable Interventional

A Scaleable Video Coaching Intervention for Opioid-using Mothers

NCT04749771
View directory record Official record
Conditions
Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
Interventions
Filming Interactions to Nurture Development, The Healthy Toddler Program
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Up to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Sep 5, 2026, 5:25 PM EDT
Active, not recruiting Not applicable Interventional

An Intervention to Enhance Well-Being in Trauma Exposed New Mothers

NCT05474534
View directory record Official record
Conditions
Post-traumatic Stress Disorder, Dissociation, Maternal Care Patterns, Infant Behavior, Maternal Behavior, Maternal Distress, Mood Disturbance, Emotional Regulation
Interventions
Neurofeedback (MUSE 2)
Device
Lead sponsor
Wayne State University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) During Pregnancy

NCT05822531
View directory record Official record
Conditions
Cardiovascular Diseases, Pregnancy Related, Sedentary Behavior
Interventions
Maternal CVH Intervention
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
18 Years and older · Female only
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Altoona, Pennsylvania • Danville, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 28, 2025 · Synced Sep 5, 2026, 5:25 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Mother Infant Nutrition Study

NCT04132310
View directory record Official record
Conditions
Pregnancy Related, Infant Development
Interventions
N/A This is an observational study.
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Sep 5, 2026, 5:25 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent-Child Memory Study: Improving Future Thinking Among Mothers

NCT06145919
View directory record Official record
Conditions
Behavior, Health
Interventions
Episodic Future Thinking (EFT), Episodic Recent Thinking (ERT)
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
5 Years and older · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 13, 2025 · Synced Sep 5, 2026, 5:25 PM EDT