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Showing 1–24 of 68 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mother-Child Relations Clear all
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Maternal & Offspring Microbiome Study

NCT05123612
View directory record Official record
Conditions
Pregnancy Related, Microbiome, Immune Function, Inflammation
Interventions
Fiber, Fermented Foods
Behavioral
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
135 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2029
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Children's Learning Centers Group FNI

NCT03908268
View directory record Official record
Conditions
Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem, Development Delay
Interventions
Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
Behavioral
Lead sponsor
Columbia University
Other
Eligibility
24 Months to 57 Months
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cos Cob, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Safe Mothers, Safe Children Initiative

NCT04752618
View directory record Official record
Conditions
PTSD, Depression, Child Maltreatment
Interventions
P-STAIR, Supportive Counseling
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Healthy Moms-Healthy Kids: Reducing Maternal Depression for Better Outcomes in Head Start Children

NCT02145273
View directory record Official record
Conditions
Maternal Depression, Parenting Behavior, Health, Interpersonal Relationships, Goal Directed Behavior, Child Behavior, Child School Readiness
Interventions
Interpersonal Psychotherapy for Depression -Group
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Female only
Enrollment
208 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
2
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2019 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Parent Encouragement And Coaching of Happiness in Youth

NCT06725160
View directory record Official record
Conditions
Depression, Parent-Child Relations
Interventions
Parent Coaching, Active Control
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
4 Years to 99 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Improving Future Thinking Among Mothers to Reduce Harsh Parenting and Improve Child Outcomes

NCT05229146
View directory record Official record
Conditions
Behavioral Health
Interventions
Episodic Future Thinking
Behavioral
Lead sponsor
Henry Ford Health System
Other
Eligibility
Female only
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 13, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Recruiting Not applicable Interventional

Parenting STAIR: Adapting a Trauma-Focused Parenting Intervention for Military-Connected Mothers and Their Children

NCT06262178
View directory record Official record
Conditions
PTSD, Depression, Parent-Child Relations
Interventions
Parenting-STAIR Modular (PSTAIR-M), Treatment as Usual (TAU)
Behavioral
Lead sponsor
New York University
Other
Eligibility
18 Years and older · Female only
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
3
States / cities
El Paso, Texas • Killeen, Texas • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Northwell Health Visits: A Family Connects Pilot Implementation at Northwell Health

NCT03887910
View directory record Official record
Conditions
Unspecified Child Maltreatment, Suspected, Unspecified Child Maltreatment, Confirmed, Postpartum Depression
Interventions
Enhanced Intervention, Intervention
Other
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
840 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Manhasset, New York
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

STEPuP: Prenatal Provider Education and Training to Improve Medication-assisted Treatment Use During Pregnancy

NCT04527926
View directory record Official record
Conditions
Opioid-use Disorder, Pregnancy Related
Interventions
STEPuP Intervention, Usual Care
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
1,022 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Enrolling by invitation Not applicable Interventional

MIO-CPP to Improve the Well-being, Permanency, and Safety Outcomes for Young Children at Risk of or in Out-of-home Placement in Philadelphia and Bucks Counties, and Affected by Maternal Substance Use

NCT04294134
View directory record Official record
Conditions
Substance Use Disorders, Parent-Child Relations, Parent Child Abuse
Interventions
MIO-CPP, MIO-CPP-CRS
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
Female only
Enrollment
320 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 14, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Interventions for Depressed Low Income Mothers and Their Infants

NCT00105573
View directory record Official record
Conditions
Depression
Interventions
Maternal interpersonal psychotherapy (IP), Infant-parent psychotherapy, Informational meetings plus treatment as usual
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 44 Years · Female only
Enrollment
218 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 29, 2013 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational

Attitudes Behavior and Practices of Mothering Among an Online Panel

NCT04871659
View directory record Official record
Conditions
Tantrum, Relation, Family, Parent-Child Relations, Parenting
Interventions
Online Survey completion
Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
374 participants
Timeline
2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Results available

Association Between Mother and Child Weight Gain: Statistical Methods With Validation

NCT04174521
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
0 Years and older
Enrollment
20,670 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jan 30, 2022 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

RESPECT-PLUS: Services for Infants With Prenatal Opiate Exposure

NCT02334111
View directory record Official record
Conditions
Opioid Use Disorder, Neonatal Abstinence Syndrome, Child Development, Child Abuse, Child Neglect
Interventions
RESPECT-Plus
Behavioral
Lead sponsor
Boston Medical Center
Other
Eligibility
Up to 21 Days
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 15, 2017 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Preventing Early Childhood Obesity, Part 1: Long-term Follow-up

NCT05424471
View directory record Official record
Conditions
Obesity, Water; Lack of, Childhood Obesity, Feeding Behavior, Mother-Child Relations, Dietary Habits
Interventions
Family Spirit Nurture (FSN), Control Group - Vehicle Safety
Behavioral · Other
Lead sponsor
Johns Hopkins Bloomberg School of Public Health
Other
Eligibility
13 Years and older · Female only
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Shiprock, New Mexico
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Not listed Not applicable Interventional

A Scaleable Video Coaching Intervention for Opioid-using Mothers

NCT04749771
View directory record Official record
Conditions
Child Behavior, Parent-Child Relations, Substance Use, Substance Abuse
Interventions
Filming Interactions to Nurture Development, The Healthy Toddler Program
Behavioral
Lead sponsor
University of Oregon
Other
Eligibility
Up to 50 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 28, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Mother Infant Nutrition Study

NCT04132310
View directory record Official record
Conditions
Pregnancy Related, Infant Development
Interventions
N/A This is an observational study.
Other
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
2
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Where Does Hope Fit In? The Relationship Between Hope, Uncertainty, and Coping Efficacy in Mothers of Children With Duchenne/Becker Muscular Dystrophy

NCT02194725
View directory record Official record
Conditions
Stress
Interventions
Not listed
Lead sponsor
National Human Genome Research Institute (NHGRI)
NIH
Eligibility
18 Years and older
Enrollment
228 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Sleep-Safe: A Strong African American Families Study

NCT03505203
View directory record Official record
Conditions
Weight Gain
Interventions
Sleep Soothe, Sleep Safe
Behavioral
Lead sponsor
University of Georgia
Other
Eligibility
17 Years and older
Enrollment
234 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Athens, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Maternal Risk Factors for Autism Spectrum Disorders: A Case-Control Approach

NCT05453708
View directory record Official record
Conditions
Autism, Autism Spectrum Disorder, Autistic Disorder, Pregnancy Related, Diet, Healthy, Diet; Deficiency, Folate Deficiency, Folic Acid Deficiency, Folic Acid Overdose
Interventions
Survey
Other
Lead sponsor
Walden University
Other
Eligibility
18 Years and older · Female only
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 19, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

MOSAIC (MOthers' AdvocateS In the Community) for Pregnant Women and Mothers of Children Under 5 With Experience of Intimate Partner Violence

NCT05106361
View directory record Official record
Conditions
Intimate Partner Violence, Depression, Post Traumatic Stress Disorder
Interventions
MOSAIC Plus, MOSAIC
Behavioral
Lead sponsor
Michigan State University
Other
Eligibility
18 Years and older · Female only
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Flint, Michigan
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms: Impact on Child Development

NCT05400161
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations, Child Development
Interventions
MoodGym, Social Media-Based Parenting Program
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 21, 2025 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional Results available

Social Media-Based Parenting Program for Women With Postpartum Depressive Symptoms

NCT04045132
View directory record Official record
Conditions
Postpartum Depression, Parenting, Parent-Child Relations
Interventions
Social Media-Based Parenting Program, MoodGym
Behavioral
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
18 Years and older · Female only
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Jul 21, 2026, 5:04 AM EDT
Completed Not applicable Interventional

Impact Evaluation of MotherWise Program

NCT02792309
View directory record Official record
Conditions
Parenting, Family Relations, Marriage, Mother-Child Relations
Interventions
MotherWise Program
Behavioral
Lead sponsor
Mathematica Policy Research, Inc.
Other
Eligibility
18 Years and older · Female only
Enrollment
953 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jul 21, 2026, 5:04 AM EDT