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Showing 1–24 of 76 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Motivational Enhancement Clear all
Completed Not applicable Interventional Results available

Motivational Coaching to Enhance Mental Health Engagement in Rural Veterans

NCT01893983
View directory record Official record
Conditions
Mental Health, Rural Health, Veterans Health
Interventions
Motivational Coaching
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
418 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
2
States / cities
North Little Rock, Arkansas • San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 26, 2019 · Synced Jun 10, 2026, 5:15 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Adaptive Self-Efficacy-Based AI Coaching for Cycling

NCT07318233
View directory record Official record
Conditions
Exercise Training, Exercise Behavior, Exercise Adherence Challenges, Motivation for Physical Activity, Motivational Enhancement
Interventions
Group 1: Self-efficacy-based AI coaching, Group 2: Static AI Affirmations
Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years to 40 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Coral Gables, Florida
Source: ClinicalTrials.gov public record
Updated Mar 2, 2026 · Synced Jun 10, 2026, 5:15 AM EDT
Suspended Phase 3 Interventional Accepts healthy volunteers

Glutamatergic Modulation to Facilitate the Behavioral Treatment of Cocaine Use Disorders

NCT03344419
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
CI-581a, CI-581b, Motivational Enhancement Therapy (MET), Mindfulness Based Relapse Prevention
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2024 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 2 Interventional

NEW DAY: Nutrition, Exercise, Weight Loss, Diabetes And You

NCT00007800
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Obesity
Interventions
Behavioral Group Weight Loss Intervention, Motivational Interviewing
Behavioral
Lead sponsor
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Eligibility
19 Years and older · Female only
Enrollment
218 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2002
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 13, 2010 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Ready for Change: Enhancing Motivational Engagement Prior to IIPT

NCT04093921
View directory record Official record
Conditions
Chronic Pain
Interventions
MET-based therapy, Standard Care
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
8 Years to 18 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 3, 2025 · Synced Jun 10, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

Motivational Interviewing to Enhance Behavioral Change in Older Adults with Hoarding Disorder

NCT05237466
View directory record Official record
Conditions
Hoarding Disorder
Interventions
RECLAIM: Reducing Clutter and Increasing Meaning, Sorting Practice
Behavioral
Lead sponsor
Mississippi State University
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Starkville, Mississippi
Source: ClinicalTrials.gov public record
Updated Nov 19, 2024 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ultrasound and Motivational Enhancement for Prenatal Smoking Cessation

NCT00013793
View directory record Official record
Conditions
Pregnancy, Smoking
Interventions
Motivational enhancement and ultrasound
Behavioral
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
16 Years and older · Female only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 23, 2005 · Synced Jun 10, 2026, 5:15 AM EDT
Not listed Not applicable Interventional

Training Therapists in Motivational Interviewing

NCT03322202
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Motivational Interviewing
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 13, 2020 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 3 Interventional

Motivational Incentives for Enhanced Drug Abuse Recovery: Drug Free Clinics - 1

NCT00033007
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
Up to 99 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2003
U.S. locations
11
States / cities
Los Angeles, California • Alamosa, Colorado • Littleton, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 2 Interventional

Increasing Treatment Adherence in Co-Occurring Psychiatric and Drug Use Disorders

NCT00237822
View directory record Official record
Conditions
Diagnosis, Dual (Psychiatry), Psychiatric Diagnosis, Drug Use Disorders
Interventions
Adherence Feedback (AF), AF + Contingency Management (AF + CM), AF + Motivational Enhancement Therapy (AF + MET)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 85 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2007
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 16, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 1 Interventional

Preserving Function Among Disability Applicants

NCT00530985
View directory record Official record
Conditions
Disability
Interventions
Benefits Counseling, VA Orientation
Behavioral
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 1, 2009 · Synced Jun 10, 2026, 5:15 AM EDT
Not listed Phase 2 Interventional

The Aim of This Study is to Determine the Effectiveness of a Motivational Enhancement Intervention in Reducing Risk Behaviors (Drug and Alcohol Use, Sexual Risk Behavior, Poor Adherence to Medications) Among HIV+ Youth. - 1

NCT00227825
View directory record Official record
Conditions
Adherence, HIV Risk Behaviors, Alcohol & Drug Use, Health Behaviors, Sexual Risk Behaviors
Interventions
Motivational interviewing
Behavioral
Lead sponsor
National Institute on Drug Abuse (NIDA)
NIH
Eligibility
16 Years to 24 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 10, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 4 Interventional

Behavioral Therapy Plus Naltrexone for Alcoholism

NCT00000456
View directory record Official record
Conditions
Alcoholism, Alcohol Dependence
Interventions
naltrexone (Revia), cognitive behavior therapy, motivational enhancement therapy
Drug · Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 70 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2002
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Oct 3, 2010 · Synced Jun 10, 2026, 5:15 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Improving Relationships Using Motivational Interviewing

NCT05696964
View directory record Official record
Conditions
Physician-Patient Relations, Diabetes Mellitus, Type 2
Interventions
Motivational interviewing training enhanced with artificial intelligence
Behavioral
Lead sponsor
Wright State University
Other
Eligibility
21 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
2
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 4, 2024 · Synced Jun 10, 2026, 5:15 AM EDT
Completed No phase listed Observational

mMe: Motivational Monitoring to Enhance Smoking Cessation Among Cancer Patients

NCT05370859
View directory record Official record
Conditions
Smoking Behaviors, Cancer, Motivation
Interventions
There is no intervention for this study
Other
Lead sponsor
University of Virginia
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 2, 2024 · Synced Jun 10, 2026, 5:15 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Peer MI for Substance-using Emerging Adults

NCT03264872
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Peer-Enhanced Motivational Interviewing, Waitlist Control
Behavioral · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
18 Years to 29 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2018 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Motivational Enhancement System for Adherence

NCT01009749
View directory record Official record
Conditions
HIV
Interventions
Motivational Enhancement System for Adherence (MESA), Motivational Enhancement System for Health (MESH)
Behavioral
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
16 Years to 24 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
13
States / cities
Los Angeles, California • San Francisco, California • Washington D.C., District of Columbia + 10 more
Source: ClinicalTrials.gov public record
Updated Jul 31, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of RME on Engagement in Buprenorphine Treatment

NCT05184907
View directory record Official record
Conditions
Opioid Use Disorder, Behavioral Symptoms, Psychiatric or Mood Diseases or Conditions
Interventions
Remote Motivational Enhancement (RME) Intervention Arm, Information Only
Behavioral · Other
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 4, 2024 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 2 Interventional Results available

Supported Employment: Motivational Enhancement for Entry and Outcome

NCT01041976
View directory record Official record
Conditions
Psychotic Disorders, Bipolar Disorder, Unemployment
Interventions
Adapted Motivational Interviewing (AMI), Support and Education for Recovery (SER)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
168 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Bedford, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 7, 2016 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 3 Interventional

Motivational Enhancement to Improve Treatment Engagement and Outcome in Subjects Seeking Treatment for Substance Abuse - 1

NCT00032981
View directory record Official record
Conditions
Substance-Related Disorders
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Yale University
Other
Eligibility
18 Years to 99 Years
Enrollment
561 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2004
U.S. locations
6
States / cities
San Francisco, California • Tarzana, California • Norwalk, Connecticut + 2 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Phase 2 Interventional Results available

The Impact of Psychopathic Traits on the Efficacy of a Substance Use Intervention

NCT01532934
View directory record Official record
Conditions
Substance Use, Psychopathy
Interventions
motivational enhancement therapy, standard care
Behavioral · Other
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 11, 2016 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Web-Based Adolescent Motivational Enhancement Study

NCT02584621
View directory record Official record
Conditions
Alcohol Risk Behaviors, Health Care Services Quality of Care
Interventions
Check Yourself App with Feedback
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
13 Years to 18 Years
Enrollment
148 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
3
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 4, 2017 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Internet Obesity Treatment Enhanced With Motivational Interviewing

NCT01232699
View directory record Official record
Conditions
Obesity
Interventions
Internet Obesity Treatment, Internet Obesity Treatment with MI, Contingent MI
Behavioral
Lead sponsor
University of Vermont
Other
Eligibility
18 Years and older
Enrollment
495 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Little Rock, Arkansas • Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Dec 23, 2018 · Synced Jun 10, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Substance Use Interventions for Truant Adolescents

NCT03655574
View directory record Official record
Conditions
Adolescent Problem Behavior, Truancy; Unsocialized, Marijuana Abuse, Truancy; Socialized, Substance Abuse, Alcohol Abuse
Interventions
Motivational + Family Check-up (MET+FCU), Psychoeducation
Behavioral · Other
Lead sponsor
Brown University
Other
Eligibility
12 Years to 18 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jun 2, 2024 · Synced Jun 10, 2026, 5:15 AM EDT