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Showing 1–24 of 65 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Mouth, Edentulous Clear all
Terminated Not applicable Interventional

Evaluation of Treatment With Fixture Microthread™ in Patients Missing All Teeth in the Upper Jaw, When Using One-Stage Surgery

NCT00748397
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
Fixture MicroThread (Micro-Macro)
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 7, 2008 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Multicenter Study Comparing OsseoSpeed TX With OsseoSpeed EV.

NCT01528215
View directory record Official record
Conditions
Partial Edentulism in the Maxilla or in the Mandible
Interventions
OsseoSpeed EV, OsseoSpeed TX
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Phase 4 Interventional Results available

A Study to Investigate Food Occlusion Efficacy of a Denture Adhesive in Denture Wearers

NCT03709810
View directory record Official record
Conditions
Denture Retention
Interventions
Marketed Denture Adhesive (Super Poligrip Max Seal), No Adhesive
Combination Product · Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years to 85 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 1, 2020 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Study to Compare Marginal Bone Loss Around Implants From Two Dental Implant Systems.

NCT00746187
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
ASTRA TECH Implant System; Fixture ST: Ø 4.5 cm in lengths of 9, 11 and 13 mm., 3i Osseotite® implant: Ø 4.0 in lengths of 8.5, 10, 11.5 and 13 mm
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2011
U.S. locations
2
States / cities
New York, New York • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2016 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The TREFOIL Concept 5 Year Clinical Investigation

NCT02940353
View directory record Official record
Conditions
Edentulous or Failing Dentition Mandible
Interventions
TREFOIL concept
Device
Lead sponsor
Nobel Biocare
Industry
Eligibility
18 Years to 80 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2022
U.S. locations
1
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Phase 4 Interventional Results available

Success Rate of Immediately Loaded Implants With Platform Switched Design Placed in Anterior Part of Mandible and Restored With Fixed Prostheses

NCT00780273
View directory record Official record
Conditions
Edentulism
Interventions
Ankylos Implants, Biomet 3i Prevail Implants
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2014 · Synced Jul 23, 2026, 7:08 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Soft and Hard Tissue Changes Around Implants

NCT05769673
View directory record Official record
Conditions
Edentulous Alveolar Ridge
Interventions
Placement of dental implant, Placement of stock healing abutment, Placement of customized CAD/CAM healing abutment
Procedure
Lead sponsor
East Carolina University
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Greenville, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 26, 2024 · Synced Jul 23, 2026, 7:08 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Conventionally vs. Digitally Fabricated Complete Dentures: Clinical Treatment Outcome Differences

NCT02521935
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Complete traditional dentures, Complete CADCAM dentures
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 26, 2017 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Study to Evaluate Implant Survival Rate of Astra Tech Fixture ST in the Posterior Maxilla With One-stage Surgery and Early Loading

NCT00748241
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Astra Tech Fixture ST
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2000
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 14, 2012 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Comparison of Incidence Between Two Techniques

NCT01832025
View directory record Official record
Conditions
Edentulous Posterior Maxilla
Interventions
internal maxillary sinus floor elevation technique, external maxillary sinus floor elevation technique
Procedure
Lead sponsor
Tufts University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 23, 2018 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional

Abutment Macro Design and Peri-implant Tissues

NCT02546713
View directory record Official record
Conditions
Edentulous
Interventions
Abutment with concave subcritical contour, Abutment with convex subcritical contour
Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 12, 2022 · Synced Jul 23, 2026, 7:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

The Effect of Immediate Implant Placement and Provisionalization in the Esthetic Zone

NCT02021331
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
immediate implant placement without provisionalization, immediate implant placement with immediate provisionalization
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 79 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 10, 2017 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Study to Evaluate the Effectiveness of Laser-Ablated Implant-Abutments to Promote Tissue Healing

NCT01822223
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Dental implant-abutments
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 24, 2017 · Synced Jul 23, 2026, 7:08 PM EDT
Active, not recruiting Not applicable Interventional Results available

A Clinical Study on Acuris™ - Conometric Concept for Single Tooth Restoration

NCT04063878
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Conometric Abutment and Conometric Final Cap
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 75 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
2
States / cities
Chicago, Illinois • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Implant-fixed Restorations With ANKYLOS 6.6 mm Implants in the Edentulous Maxilla - A 5-year Follow-up Study

NCT02656823
View directory record Official record
Conditions
Edentulous Maxilla
Interventions
ANKYLOS C/X implant A 6.6
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years to 80 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Feb 27, 2024 · Synced Jul 23, 2026, 7:08 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

An Observational Clinical Case Series Study to Assess Fit and Quality of Full Dentures Fabricated by AM

NCT04023006
View directory record Official record
Conditions
Mouth, Edentulous
Interventions
Removable prostheses
Device
Lead sponsor
Dentsply International
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2021 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Comparative Study of Implant Surfaces to Enhance Stabilization in Patients With Type 2 Diabetes

NCT01142297
View directory record Official record
Conditions
Partially Edentulous Mandible, Type 2 Diabetes
Interventions
dental implant and modified dental implant
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2018 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Clinical Study Comparing Submerged Versus Trans-mucosal Healing of P.004 Implants in the Anterior Mandible and Maxilla

NCT00906425
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
Straumann Bone Level Implant
Device
Lead sponsor
Institut Straumann AG
Industry
Eligibility
18 Years and older
Enrollment
145 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
2
States / cities
Boca Raton, Florida • Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2016 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Study on OsseoSpeed™ Implants Replacing 2-5 Teeth in the Posterior Upper Jaw, Restored With Provisional Teeth Attached 6-7 Weeks Later

NCT00711113
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
47 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
2
States / cities
Iowa City, Iowa • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Performance of MicroTextured Dental Implants

NCT01821417
View directory record Official record
Conditions
Partially Edentulous Jaw
Interventions
Microtextured dental implant treatment, Dental implant treatment
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
68 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Jul 23, 2026, 7:08 PM EDT
Active, not recruiting Not applicable Interventional

Non-Guided vs. Guided Surgery to Immediately Loaded PrimeTaper Implants in Partially Edentulous Patients

NCT05264545
View directory record Official record
Conditions
Partially Edentulous Maxilla or Mandible
Interventions
PrimeTaper EV
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
25 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
8
States / cities
Aurora, Colorado • Broomfield, Colorado • Oakbrook Terrace, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Jun 23, 2026 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Study on ASTRA TECH Implant System, OsseoSpeed™ Implants in Patients Missing All Teeth in the Upper Jaw, Restored With Provisional Teeth Within 24 Hours

NCT00711022
View directory record Official record
Conditions
Jaw, Edentulous
Interventions
ASTRA TECH Implant System, OsseoSpeed™, all dimensions.
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2012
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 15, 2014 · Synced Jul 23, 2026, 7:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Study of Oral Endosseous Titanium Implants in Edentulous Subjects

NCT00001211
View directory record Official record
Conditions
Ectodermal Dysplasia, Jaw, Edentulous
Interventions
Not listed
Lead sponsor
National Institute of Dental and Craniofacial Research (NIDCR)
NIH
Eligibility
Not listed
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1986 – 2000
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jul 23, 2026, 7:08 PM EDT
Completed Not applicable Interventional Results available

Study Comparing OsseoSpeed™ Implants of Two Different Lengths in the Upper and Lower Posterior Jaw

NCT00545818
View directory record Official record
Conditions
Jaw, Edentulous, Partially
Interventions
OsseoSpeed™ length 6 mm, OsseoSpeed™ length 11 mm
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
20 Years to 70 Years
Enrollment
97 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
2
States / cities
Los Angeles, California • Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 18, 2020 · Synced Jul 23, 2026, 7:08 PM EDT