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ClinicalTrials.gov public records Last synced Nov 5, 2026, 6:00 AM EST

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Showing 1–24 of 38 matching trials from the live ClinicalTrials.gov search.

Filters: Condition: Mucosal Immunity Clear all

Conditions: Shigella
Interventions: CVD 1208S, Challenge strain of wild-type Shigella flexneri 2a; Biological
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 2
States / cities: Baltimore, Maryland

Conditions: Immunity, Mucosal, Immune System Processes, Blood Specimen Collection
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 120 Years
Enrollment: 500 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Started 2010
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: COPD
Interventions: LAIV; Biological
Lead sponsor: University of North Carolina, Chapel Hill; Other
Eligibility: 40 Years and older
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2022 – 2026
U.S. locations: 1
States / cities: Chapel Hill, North Carolina

Conditions: Influenza
Interventions: Flucelvax(R), Human Challenge virus; Biological · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 55 Years
Enrollment: 82 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2020
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: HIV Infections
Interventions: MN rgp120/HIV-1 and GNE8 rgp120/HIV-1, ALVAC-HIV MN120TMG (vCP205), ALVAC-RG Rabies Glycoprotein (vCP65); Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 84 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: Ends 2000
U.S. locations: 6
States / cities: Birmingham, Alabama • Baltimore, Maryland • St Louis, Missouri + 3 more

Conditions: HIV Infections
Interventions: Ad26.ENVA.01 (rAd26), Placebo Vaccine; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2016
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Ulcerative Colitis
Interventions: Trichuris suis ova; Drug
Lead sponsor: NYU Langone Health; Other
Eligibility: 18 Years to 72 Years
Enrollment: 4 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2015
U.S. locations: 1
States / cities: New York, New York

Conditions: Initiation of Oral Contraception (OC), Initiation of Depo-Provera (DMPA), Initiation of Mirena (LNG-IUD)
Interventions: Mirena, Oral contraception, Depo-Provera; Drug
Lead sponsor: Thomas Cherpes, DVM, MD; Other
Eligibility: 15 Years to 25 Years · Female only
Enrollment: 7 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2013
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Mucosal Immunity
Interventions: Fluzone; Drug
Lead sponsor: John Sundy; Other
Eligibility: 18 Years to 50 Years
Enrollment: 60 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2011
U.S. locations: 1
States / cities: Durham, North Carolina

Conditions: Influenza, COVID-19
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 120 Years
Enrollment: 75 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Respiratory Tract Infections, Cold Symptoms, Exhaled Nitric Oxide
Interventions: Beetroot juice; Dietary Supplement
Lead sponsor: Southern Methodist University; Other
Eligibility: 18 Years to 30 Years
Enrollment: 150 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2026
U.S. locations: 2
States / cities: Dallas, Texas • Waco, Texas

Conditions: HIV Infections
Interventions: TBC-3B; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 33 Years
Enrollment: 12 participants
Healthy volunteers: Accepts healthy volunteers
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: HIV Negative, Adaptive Immunity, Innate Immunity
Interventions: VRC-HIVDNA016-00-VP, VRC-HIVADV014-00-VP; Biological
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 50 Years
Enrollment: 36 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2014
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Genital Tract Mucosal Immunity, Genital Tract Microflora
Interventions: IUD placement, Levonorgestrel IUD, Copper T380A IUD; Drug
Lead sponsor: Sharon Achilles; Other
Eligibility: 18 Years to 40 Years · Female only
Enrollment: 42 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010 – 2011
U.S. locations: 1
States / cities: Pittsburgh, Pennsylvania

Conditions: Gonorrhoea
Interventions: Meningococcal Group B Vaccine, Placebo; Biological · Other
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 49 Years
Enrollment: 52 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Decatur, Georgia

Conditions: Normal Physiology
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 18 Years to 49 Years
Enrollment: 10 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2012 – 2019
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Influenza Immunity
Interventions: Not listed
Lead sponsor: National Institute of Allergy and Infectious Diseases (NIAID); NIH
Eligibility: 2 Years to 17 Years
Enrollment: 65 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Yogurt Intake, Gastrointestinal Immune Function, Gut Microbiome, Gut Health
Interventions: Yogurt Intervention; Other
Lead sponsor: USDA, Western Human Nutrition Research Center; Federal
Eligibility: 50 Years to 75 Years
Enrollment: 32 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2024
U.S. locations: 1
States / cities: Davis, California

Conditions: Healthy
Interventions: Whole grain diet, Refined grain diet; Dietary Supplement
Lead sponsor: University of Florida; Other
Eligibility: 11 Years to 15 Years
Enrollment: 83 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Gainesville, Florida

Conditions: Vaccinia, Virus Diseases
Interventions: JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, Phlebotomy, Research bronchoscopy, Skin punch biopsy, Bone marrow aspiration; Biological · Procedure
Lead sponsor: Washington University School of Medicine; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: St Louis, Missouri

Conditions: Asthma, Allergic Rhinitis, Cat Allergy, Healthy
Interventions: Research Grade RG-RV; Biological
Lead sponsor: The University of Texas Medical Branch, Galveston; Other
Eligibility: 18 Years to 60 Years
Enrollment: 75 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2023 – 2027
U.S. locations: 1
States / cities: Galveston, Texas

Conditions: Impact of Vaccination
Interventions: Live Attenuated Influenza Vaccine; Biological
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 2 Years to 89 Years
Enrollment: 25 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2027 – 2029
U.S. locations: 1
States / cities: Baltimore, Maryland

Conditions: Contraception
Interventions: Not listed
Lead sponsor: Thomas L. Cherpes; Other
Eligibility: 15 Years to 25 Years · Female only
Enrollment: 90 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2013 – 2016
U.S. locations: 1
States / cities: Stanford, California

Conditions: Shigella
Interventions: CVD 1208S, a Shigella flexneri 2a live, oral vaccine, Placebo; Biological · Other
Lead sponsor: University of Maryland, Baltimore; Other
Eligibility: 18 Years to 45 Years
Enrollment: 20 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2010
U.S. locations: 1
States / cities: Baltimore, Maryland

Search by objective public record fields.

Safety and Efficacy Challenge Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella: Phase IIb

VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older

Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD)

Mucosal and Systemic Immunity After Viral Challenge of Healthy Volunteers Vaccinated With Inactivated Influenza Vaccine Via the Intranasal Versus Intramuscular Route

A Randomized Phase I Safety and Immunogenicity Trial of Live Recombinant Canarypox ALVAC-HIV vCP205 Delivered by Alternate Mucosal Routes in HIV-1 Uninfected Adult Volunteers

Evaluating the Safety and Immune Response of an Adenovirus-Based HIV Vaccine in HIV-Uninfected Adults

Mucosal Immunity of Ulcerative Colitis Patients Undergoing Therapy With Trichuris Suis Ova

Modulation of Mucosal and Systemic Immunity by Hormonal Contraceptives

Strategies for Enhancing Mucosal Immunity to Influenza Vaccine

Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

Beetroot Juice NO Cold Study

Determining an Effective Site (Groin Versus Arm) for Giving HIV Vaccines

Immune Responses to Two Experimental HIV Vaccines in Healthy Adults

Study of Immune Cell Changes in the Genital Tract 2 Months After Initiation of an IUD for Contraception

Mucosal Immunity Against Neisseria Gonorrhoeae After 4CMenB Vaccination

Studying Cell Immune Responses to a Live Flu Vaccine in Healthy Adults

Natural History of Systemic and Nasal Mucosal Immunity After Influenza Vaccination in a Pediatric Population

Yogurt and GI Health

The Addition of Whole Grains to the Diets of Middle-school Children

Evaluating the Human Immune Response to the JYNNEOS Vaccine

Viral Mucosal Reprogramming

Intranasal LAIV Mucosal Immunity Examination

Modulation of Immunity by Hormonal Contraceptives

Safety and Efficacy Study of CVD 1208S, a Live, Attenuated Oral Vaccine to Prevent Shigella Infection: Phase IIa