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Showing 1–24 of 25 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Multifocal Intraocular Lens Clear all
Completed Phase 4 Interventional

Efficacy of Topical Ketorolac Versus Placebo for Improving Visual Outcomes Following Multifocal IOL Implantation

NCT00433225
View directory record Official record
Conditions
Macula Thickening
Interventions
Prednisolone Acetate, Ketorolac 0.4%, Gatifloxacin 0.3%
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
50 Years and older
U.S. locations
1
States / cities
Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated Sep 9, 2007 · Synced Jul 23, 2026, 1:49 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens

NCT04128514
View directory record Official record
Conditions
Cataract
Interventions
Panoptix Toric
Device
Lead sponsor
Eye Center of North Florida
Other
Eligibility
40 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Panama City, Florida
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Jul 23, 2026, 1:49 AM EDT
Withdrawn Phase 4 Interventional

Clinical Assessment of Visual Function With the Acrysof ReSTOR Multifocal IOL

NCT00758940
View directory record Official record
Conditions
Visual Outcomes
Interventions
Acrysof ReSTOR multifocal IOL
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated May 11, 2015 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional

Evaluation Of Bilateral Tecnis Multifocal Versus ReSTOR 3D Intraocular Lenses

NCT01061918
View directory record Official record
Conditions
Cataract
Interventions
Tecnis MF, ReSTOR
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Miami, Florida • Sarasota, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2011 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

Clinical Assessment of Visual Function With the Acrysof ReSTOR Multifocal IOL

NCT00759096
View directory record Official record
Conditions
Visual Acuity
Interventions
RESTOR IOL Model SA60D3
Device
Lead sponsor
Alcon Research
Industry
Eligibility
21 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Dec 4, 2023 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

Tecnis ZLB00 & Symfony Intraocular Lens Combination Outcomes

NCT03771274
View directory record Official record
Conditions
Cataract Bilateral, Presbyopia
Interventions
Tecnis ZLB00 & Symfony IOL
Device
Lead sponsor
Carolina Eyecare Physicians, LLC
Other
Eligibility
40 Years and older
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Mt. Pleasant, South Carolina
Source: ClinicalTrials.gov public record
Updated Aug 9, 2020 · Synced Jul 23, 2026, 1:49 AM EDT
Completed No phase listed Observational Results available

AcrySof® Bilateral PanOptix(R) Spectacle Freedom and Patient Satisfaction Study

NCT04126187
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
40 Years and older
Enrollment
30 participants
Timeline
2020 – 2021
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 20, 2023 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Visual Outcomes of Subjects Bilaterally Implanted With ReSTOR Aspheric +4 vs. Tecnis or Acri.LISA

NCT00721253
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR, Tecnis, Acri.LISA
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 15, 2010 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional Results available

Contralateral ReSTOR / Monofocal or Phakic Eye

NCT00731640
View directory record Official record
Conditions
Cataracts
Interventions
ReSTOR
Device
Lead sponsor
Alcon Research
Industry
Eligibility
18 Years and older
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2007
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Mar 22, 2010 · Synced Jul 23, 2026, 1:49 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

A Clinical Assessment of the Full Range of Functional Vision With Three Tecnis Multifocal IOL 1-Piece Models in Bilateral Cataract Extraction

NCT02863159
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal 1-Piece IOL
Device
Lead sponsor
Dell Laser Consultants
Other
Eligibility
21 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Jul 23, 2026, 1:49 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Multifocals and Accommodating/Bilateral Implantation of Different Multifocal Intraocular Lens (IOLs)

NCT00934960
View directory record Official record
Conditions
Cataracts
Interventions
Not listed
Lead sponsor
Medical University of South Carolina
Other
Eligibility
40 Years to 90 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Nov 17, 2009 · Synced Jul 23, 2026, 1:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Evaluation of Quality of Vision and Spectacle Independence With the AcrySof® Panoptix® Intraocular Lens

NCT04124952
View directory record Official record
Conditions
Cataract
Interventions
Panoptix
Device
Lead sponsor
SightTrust Eye Institute
Other
Eligibility
40 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Sunrise, Florida
Source: ClinicalTrials.gov public record
Updated Nov 21, 2023 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers Results available

Clinical Investigation of Expanded Designs of a Multifocal IOL

NCT01714635
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal Intraocular Lens, Monofocal Intraocular Lens
Device
Lead sponsor
Abbott Medical Optics
Industry
Eligibility
18 Years and older
Enrollment
445 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
17
States / cities
Tucson, Arizona • Rogers, Arkansas • Bakersfield, California + 14 more
Source: ClinicalTrials.gov public record
Updated Mar 16, 2015 · Synced Jul 23, 2026, 1:49 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparative Study of Photopic and Mesopic Distance, Intermediate and Near Visual Acuity, and Spectacle Independence

NCT01191502
View directory record Official record
Conditions
Visual Acuity
Interventions
Not listed
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 5, 2011 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluating Refractive and Visual Outcomes With the Alcon Toric ReSTOR +2.5 and +3.0 Models

NCT03856944
View directory record Official record
Conditions
Cataract
Interventions
ReSTOR Toric
Device
Lead sponsor
Gainesville Eye Associates
Other
Eligibility
30 Years and older
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jul 23, 2026, 1:49 AM EDT
Enrolling by invitation Not applicable Interventional

Visual Outcomes in Patients Contralaterally Implanted With PanOptix Pro and Clareon Vivity Compared to Bilateral Implantation of PanOptix Pro

NCT07076277
View directory record Official record
Conditions
Cataract, Multifocal Intraocular Lens
Interventions
Clareon PanOptix Pro and Clareon Vivity Intraocular Lens, Clareon PanOptix Pro Intraocular Lenses
Device
Lead sponsor
Brian Shafer
Other
Eligibility
18 Years and older
Enrollment
346 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
5
States / cities
Baltimore, Maryland • Alexandria, Minnesota • Bozeman, Montana + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 21, 2025 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Prospective Evaluation of Visual Outcomes With Tecnis One-Piece Multifocal Intraocular Lenses Compared With Patients Previously Implanted With Crystalens Aspheric Optic (AO)

NCT01191229
View directory record Official record
Conditions
To Collect Information About Visual Outcomes and Participant Satisfaction
Interventions
Tecnis one-piece MF IOL, Crystalens AO
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Lake Villa, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 13, 2012 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Not applicable Interventional Results available

Investigation of the Safety and Effectiveness of a Trifocal IOL

NCT04176965
View directory record Official record
Conditions
Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
Interventions
FINEVISION HP IOL, Alcon AcrySof SN60AT
Device
Lead sponsor
Beaver-Visitec International, Inc.
Industry
Eligibility
22 Years and older
Enrollment
539 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
20
States / cities
Northridge, California • Orange, California • Orland Park, Illinois + 17 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2025 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional

Selection of Aspheric Diffractive Multifocal Intraocular Lens (IOLS) Based on Corneal Wavefront

NCT00999492
View directory record Official record
Conditions
Cataracts
Interventions
Tecnis® Multifocal (TMF)
Device
Lead sponsor
Mark Packer, MD, FACS
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional

Efficacy of Topical Cyclosporine Versus Tears for Improving Visual Outcomes Following Multifocal IOL Implantation

NCT00349583
View directory record Official record
Conditions
Cataract, Dry Eye
Interventions
Topical Cyclosporine, Tears
Drug
Lead sponsor
Innovative Medical
Industry
Eligibility
50 Years and older
U.S. locations
1
States / cities
Rockville Centre, New York
Source: ClinicalTrials.gov public record
Updated May 31, 2007 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Clinical Evaluation of the Lenstec SBL-3 Multifocal Intraocular Lens

NCT02487160
View directory record Official record
Conditions
Cataracts, Presbyopia
Interventions
SBL-3 multifocal intraocular lens, Control monofocal intraocular lens
Device
Lead sponsor
Lenstec Incorporated
Industry
Eligibility
22 Years and older
Enrollment
499 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
13
States / cities
Dothan, Alabama • Santa Maria, California • Cape Coral, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 22, 2023 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional

Comparison of Postoperative Visual Acuity and Spectacle Independence Between the Tecnis Multifocal Intraoculer Lens (IOL) and the Crystalens Accommodating IOL

NCT01275118
View directory record Official record
Conditions
Cataract
Interventions
Tecnis Multifocal IOL, crystalens Accommodating IOL
Device
Lead sponsor
Mark Packer, MD, FACS
Other
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 27, 2014 · Synced Jul 23, 2026, 1:49 AM EDT
Completed Phase 4 Interventional

Evaluation of the Tecnis™ Multifocal and Crystalens™ Accommodating Intraocular Lenses

NCT01061281
View directory record Official record
Conditions
Aphakia
Interventions
Tecnis MF IOL, Crystalens AO IOL
Device
Lead sponsor
Innovative Medical
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Cape Coral, Florida
Source: ClinicalTrials.gov public record
Updated Jan 17, 2012 · Synced Jul 23, 2026, 1:49 AM EDT
Recruiting Not applicable Interventional

Visual Performance of Clareon PanOptix vs. a Comparable Multifocal Intraocular Lens

NCT07006428
View directory record Official record
Conditions
Age Related Cataracts
Interventions
Clareon PanOptix or PanOptix Toric IOLs, Comparable multifocal IOL
Device
Lead sponsor
Argus Research Center, Inc.
Other
Eligibility
Not listed
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
3
States / cities
Torrance, California • Cape Coral, Florida • Gainesville, Georgia
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Jul 23, 2026, 1:49 AM EDT