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Showing 1–24 of 29 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Multimorbidity Clear all
Enrolling by invitation Not applicable Interventional

Living With Multimorbidity: Care Coordination and Symptom Management Program (COORDINATE)

NCT07157982
View directory record Official record
Conditions
Multimorbidity
Interventions
COORDINATE Program, Enhanced Usual Care
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
50 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 28, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Recruiting Not applicable Interventional

Transition to Cardiac Rehabilitation (T2CR) to Address Barriers of Multimorbidity and Frailty

NCT06244199
View directory record Official record
Conditions
Cardiovascular Diseases, Cardiac Rehabilitation, Transition of Care
Interventions
T2CR Intervention, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2025 · Synced Sep 4, 2026, 6:36 AM EDT
Recruiting Not applicable Interventional

Comparing Healthcare Visit Recording and Open Notes to Improve Chronic iLlness Care Experience in Older Adults

NCT05955339
View directory record Official record
Conditions
Diabetes Mellitus, Hypertension
Interventions
NOTES, AUDIO
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
18 Years and older
Enrollment
1,022 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
3
States / cities
Manchester, New Hampshire • Nashville, Tennessee • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 17, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Not listed No phase listed Observational

Bictegravir in the Elderly Living With HIV (BICEP)

NCT05064020
View directory record Official record
Conditions
HIV-1-infection
Interventions
Bictegravir/Emtricitabine/Tenofovir Alafenamide 50 MG-200 MG-25 MG Oral Tablet [BIKTARVY]
Drug
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
18 Years and older
Enrollment
162 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Buffalo, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2024 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional

Improving Patient and Caregiver Engagement by Sharing Annotated Audio-recorded Clinic Visits

NCT04827381
View directory record Official record
Conditions
Multimorbidity
Interventions
Annotated Audio, Audio
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Manchester, New Hampshire
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Evaluating the Accuracy of an Integrated Vital Sign Measurement Platform

NCT03589716
View directory record Official record
Conditions
Multimorbidity
Interventions
Vital Moto Mod, Welch Allyn Connex Spot Vital Signs Monitor, Capnostream 20 Portable Bedside Capnograph, Welch Allyn 767 Mobile Aneroid Sphygmomanometerand 3M Littmann Master Classic II Teaching Stethoscope, Scifit 1000R cycle ergometer
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
265 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Sep 4, 2026, 6:36 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Physical Activity Modifies Exercise Responsiveness

NCT07792967
View directory record Official record
Conditions
Multimorbidity
Interventions
SLIMM - Sit less, interact, move more, PB125
Behavioral · Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2027 – 2031
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional

Self-Management Interventions Using Mobile Health for the Multimorbid

NCT04566107
View directory record Official record
Conditions
Multiple Chronic Conditions
Interventions
mHealth intervention, mHealth Plus
Behavioral
Lead sponsor
University of Nebraska
Other
Eligibility
19 Years and older
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Lincoln, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 25, 2023 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional

Optimal Medication Management in Alzheimer's Disease and Dementia

NCT03984396
View directory record Official record
Conditions
Dementia
Interventions
Educational Materials - Patient & Clinician
Other
Lead sponsor
Kaiser Permanente
Other
Eligibility
65 Years and older
Enrollment
7,398 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 31, 2024 · Synced Sep 4, 2026, 6:36 AM EDT
Recruiting Not applicable Interventional

Annual Wellness Visits vs GRACE-augmented Annual Wellness Visits For Older Adults With High Needs - Phase 2

NCT07166861
View directory record Official record
Conditions
Aging, Preventive Care, Multimorbidity, Palliative Care
Interventions
Annual Wellness Visit, Annual Wellness Visits + Geriatric Resources and Assessment for the Care of Elders (AWV + GRACE)
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
6,080 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
4
States / cities
Derby, Connecticut • Boston, Massachusetts • Winston-Salem, North Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Active, not recruiting Not applicable Interventional

Telehealth-delivered Peer Support to Improve Quality of Life Among Veterans With Multimorbidity

NCT05560451
View directory record Official record
Conditions
Multimorbidity
Interventions
Peer health coach intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Sep 4, 2026, 6:36 AM EDT
Withdrawn Not applicable Interventional

High Risk Outpatient Intern-led Care (HeROIC) Clinic Initiative

NCT04375189
View directory record Official record
Conditions
Comorbidities and Coexisting Conditions, Risk Reduction, Emergencies
Interventions
High Risk Clinic
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Sep 4, 2026, 6:36 AM EDT
Active, not recruiting No phase listed Observational

Psychosocial Syndemics of Heart Failure

NCT04637776
View directory record Official record
Conditions
Heart Failure
Interventions
Hospitalization
Other
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
367 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 27, 2024 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional

Improving Communication About Patient Priorities in Multimorbidity

NCT02100982
View directory record Official record
Conditions
Chronic Disease
Interventions
Customized Care, Care As Usual
Other
Lead sponsor
University of Rochester
Other
Eligibility
40 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 25, 2018 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Health Literacy Assessment and Intervention to Reduce Disparities: FLIGHT/VIDAS II

NCT02922439
View directory record Official record
Conditions
Fatigue, Depression, Pain, Sleep Wake Disorders, Chronic Disease
Interventions
Tailored Intervention, Control Intervention
Behavioral
Lead sponsor
Nova Southeastern University
Other
Eligibility
40 Years and older
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Sep 17, 2023 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional

Evaluation of the Philips Lifeline CareSage Risk Assessment System

NCT03126565
View directory record Official record
Conditions
Multimorbidity
Interventions
Lifeline CareSage Flagging
Other
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Waltham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2020 · Synced Sep 4, 2026, 6:36 AM EDT
Active, not recruiting Not applicable Interventional

High-Risk Veteran Initiative

NCT05050643
View directory record Official record
Conditions
Multimorbidity
Interventions
EBQI-IC, EBQI-LC
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
3
States / cities
Sepulveda, California • Pittsburgh, Pennsylvania • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 22, 2025 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional Results available

Living With Multimorbidity: CO-ORDINATE Program

NCT05985044
View directory record Official record
Conditions
Multimorbidity, Quality of Life, Symptom Management
Interventions
Care cO-ORDInatioN And sympTom managEment (CO-ORDINATE) Intervention
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
55 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2025 · Synced Sep 4, 2026, 6:36 AM EDT
Completed Not applicable Interventional Results available

Video-Enhanced Care Management for Medically Complex Veterans

NCT02962687
View directory record Official record
Conditions
Multimorbidity, Cognitive Impairments
Interventions
Care management via videoconference, Care management via telephone calls
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Sep 4, 2026, 6:36 AM EDT
Recruiting Not applicable Interventional

Multicomponent Telerehabilitation to Engage Veterans in Effective Self-Management of Complex Health Conditions

NCT06288438
View directory record Official record
Conditions
Multimorbidity, Physical Deconditioning
Interventions
Motivational Interviewing Techniques, Physical Therapy Interventions, Education, Health Status Updates, Physical Therapy Consult
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
60 Years and older
Enrollment
126 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Recruiting Not applicable Interventional

Diabetes Multimorbidity Typology, Trajectory, and Feasibility of an Audio Diary Mobile Application to Support Self-management

NCT07474376
View directory record Official record
Conditions
Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1
Interventions
Fabla Mobile App
Other
Lead sponsor
Emory University
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Aug 16, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Active, not recruiting Not applicable Interventional

The Effect of Clinic Visit Audio Recordings for Self-management in Older Adults

NCT05824572
View directory record Official record
Conditions
Diabetes
Interventions
Clinic visit audio recordings for self-management in older adults, Usual Care
Other
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
65 Years and older
Enrollment
336 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
3
States / cities
Manchester, New Hampshire • Nashville, Tennessee • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Active, not recruiting Not applicable Interventional

Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions

NCT06605807
View directory record Official record
Conditions
Prescribing Decisions, Diabetes, Multimorbidity, Hypertension, Geriatrics
Interventions
Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Sep 4, 2026, 6:36 AM EDT
Not listed No phase listed Observational

Emulated Study of Vitamin D Correction Vs Non-Correction

NCT06366776
View directory record Official record
Conditions
Vitamin D Deficiency
Interventions
Not listed
Lead sponsor
The Cooper Health System
Other
Eligibility
18 Years and older
Enrollment
9,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 21, 2025 · Synced Sep 4, 2026, 6:36 AM EDT