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Showing 1–24 of 90 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Multiple Chronic Health Conditions Clear all
Completed Not applicable Interventional Accepts healthy volunteers

MOCHA Moving Forward: a CBPR Investigation of Chronic Disease Prevention in Older, Low-income African-American Men

NCT03745703
View directory record Official record
Conditions
Chronic Disease of Cardiovascular System, Multiple Chronic Conditions, Chronic Disease
Interventions
MOCHA
Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
35 Years to 70 Years · Male only
Enrollment
261 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
2
States / cities
Amherst, Massachusetts • Springfield, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 7, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Effect of Patient Priorities Care Implementation in Older Veterans With Multiple Chronic Conditions

NCT04922320
View directory record Official record
Conditions
Multiple Chronic Conditions, Decision Making, Shared
Interventions
Patient Priorities Care, Usual Care
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
65 Years and older
Enrollment
420 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
2
States / cities
West Haven, Connecticut • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Dec 29, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Integrated Population (I-POP) Health Trial

NCT04761016
View directory record Official record
Conditions
Diabetes, Hypertension, Chronic Kidney Diseases, Obesity, Chronic Disease
Interventions
Usual Care, I-POP + CHW navigation
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
18 Years to 99 Years
Enrollment
202 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Patient-Centered Models of HCV Care for People Who Inject Drugs

NCT02824640
View directory record Official record
Conditions
Hepatitis C, Medication Adherence
Interventions
Patient Navigation, modified Directly Observed Therapy
Behavioral
Lead sponsor
Prisma Health-Upstate
Other
Eligibility
18 Years to 70 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2024 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

NCT06716411
View directory record Official record
Conditions
Persian Gulf Syndrome, Gulf War Syndrome, Multiple Chronic Illnesses, Occupational Diseases, War-Related Injuries, Wounds and Injuries
Interventions
Acupuncture
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
10
States / cities
Berkeley, California • Los Angeles, California • Colorado Springs, Colorado + 7 more
Source: ClinicalTrials.gov public record
Updated Apr 2, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Web-based Resource for Children and Adolescents About Clinical Research

NCT04448210
View directory record Official record
Conditions
Healthy, Chronic Illnesses, Multiple
Interventions
DigiKnowIt News: Teen
Behavioral
Lead sponsor
Innovation Research & Training
Other
Eligibility
12 Years to 17 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 18, 2020 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Phase 1 Interventional

FLIGHT Study for Childhood Chronic Illness

NCT06377384
View directory record Official record
Conditions
Chronic Illnesses, Multiple
Interventions
FLIGHT Intervention
Other
Lead sponsor
Documenting Hope Project
Other
Eligibility
2 Years to 15 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Windsor, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 5, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Not applicable Interventional

Real-time Symptom Monitoring Using ePROs to Prevent Adverse Events During Care Transitions

NCT05282654
View directory record Official record
Conditions
Multiple Chronic Conditions, Adverse Event
Interventions
ePRO Application
Behavioral
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Results available

Group-based Integrative Pain Management (IPMP+ Pilot)

NCT05906784
View directory record Official record
Conditions
Chronic Pain
Interventions
group acupuncture, Integrative Group Medical Visits
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jan 29, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

PREEMIE PROGRESS: A Family Management Program for Parents of Preterm Infants

NCT04638127
View directory record Official record
Conditions
Premature Infant Disease, Family Research, Parent-Child Relations, Self Efficacy, Patient Engagement, Patient Empowerment, Parenting, Chronic Conditions, Multiple
Interventions
PREEMIE PROGRESS, Attention Control
Behavioral
Lead sponsor
University of Cincinnati
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 26, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Mobile Intervention Merging Yoga and Self-Management Skills

NCT04758312
View directory record Official record
Conditions
Chronic Disease
Interventions
MY-Skills Mobile
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 11, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Active, not recruiting Not applicable Interventional

Collaboration Oriented Approach to Controlling High Blood Pressure

NCT06124716
View directory record Official record
Conditions
Hypertension, Multiple Chronic Conditions
Interventions
Enhanced COACH CDS Tool, Usual Care COACH CDS Tool
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 100 Years
Enrollment
550 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
3
States / cities
Columbia, Missouri • Portland, Oregon • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Caregiver Support in the Context of Multiple Chronic Conditions

NCT04090749
View directory record Official record
Conditions
Caregiver Burnout
Interventions
Caregiver-Support
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Jul 23, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions

NCT01931644
View directory record Official record
Conditions
All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis, Asthma, Atopic Dermatitis Eczema, Beta Thalassemia, Bipolar Disorder, Breast Cancer, Celiac Disease, Cervical Cancer, Chronic Inflammatory Demyelinating Polyneuropathy, Chronic Kidney Diseases, Chronic Obstructive Pulmonary Disease, Colon Cancer, Colorectal Cancer, Crohn's Disease, Cystic Fibrosis, Depression, Diabetes Mellitus, Duchenne Muscular Dystrophy, Endometriosis, Epilepsy, Facioscapulohumeral Muscular Dystrophy, G6PD Deficiency, General Anxiety Disorder, Hepatitis B, Hereditary Hemorrhagic Telangiectasia, HIV/AIDS, Human Papilloma Virus, Huntington's Disease, Idiopathic Thrombocytopenic Purpura, Insomnia, Kidney Cancer, Leukemia, Lung Cancer, Lupus Nephritis, Lymphoma, Melanoma, Multiple Myeloma, Multiple Sclerosis, Myositis, Myotonic Dystrophy, Ovarian Cancer, Pancreatic Cancer, Parkinson's Disease, Polycystic Kidney Diseases, Prostate Cancer, Psoriasis, Psoriatic Arthritis, Rosacea, Scleroderma, Sickle Cell Anemia, Sickle Cell Trait, Sjogren's Syndrome, Skin Cancer, Spinal Muscular Atrophy, Systemic Lupus Erythematosus, Thrombotic Thrombocytopenic Purpura, Trisomy 21, Ulcerative Colitis
Interventions
Not listed
Lead sponsor
Sanguine Biosciences
Industry
Eligibility
18 Years to 100 Years
Enrollment
17,667 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2024
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Jul 23, 2026, 1:26 AM EDT
Active, not recruiting Not applicable Interventional

Telehealth-delivered Peer Support to Improve Quality of Life Among Veterans With Multimorbidity

NCT05560451
View directory record Official record
Conditions
Multimorbidity
Interventions
Peer health coach intervention
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
298 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Health Promotion and Wellness Program for Adults With Disabling Conditions

NCT01776034
View directory record Official record
Conditions
Stroke, Multiple Sclerosis, Rheumatoid Arthritis
Interventions
SystemCHANGE Group Lifestyle counseling, Phone Lifestyle Counseling
Behavioral
Lead sponsor
Case Western Reserve University
Other
Eligibility
30 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 23, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Not listed No phase listed Observational

Medication-taking Preferences & Practices of Patients With Chronic Conditions

NCT01614353
View directory record Official record
Conditions
Any Condition in N73.0 Specified as Chronic, Adult Disease, Pharmacological Action
Interventions
Electronic Diaries, Hermeneutic Interviews
Other
Lead sponsor
Washington State University
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
2
States / cities
Spokane, Washington
Source: ClinicalTrials.gov public record
Updated Dec 20, 2012 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Phase 2 Interventional

NAVIGATE Kidney: A Multi-level Intervention to Reduce Kidney Health Disparities

NCT06810622
View directory record Official record
Conditions
Kidney Diseases, Chronic Kidney Diseases
Interventions
Community health worker intervention, Standard Care (in control arm)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 75 Years
Enrollment
448 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Denver, Colorado • Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed Not applicable Interventional

Health Coaching for Chronic Multisymptom Illness

NCT04157101
View directory record Official record
Conditions
Pain Predominant Chronic Multisymptom Illness
Interventions
Health Coaching, Supportive Psychotherapy
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
Not listed
Enrollment
260 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
East Orange, New Jersey
Source: ClinicalTrials.gov public record
Updated Apr 19, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Active, not recruiting No phase listed Observational

Virta Health Registry

NCT03474692
View directory record Official record
Conditions
Multiple Chronic Conditions, Chronic Disease, Disease Progression, Long-Term Care, Telemedicine
Interventions
Not listed
Lead sponsor
Virta Health
Industry
Eligibility
Not listed
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2039
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jul 23, 2026, 1:26 AM EDT
Not yet recruiting Not applicable Interventional

Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress

NCT07483333
View directory record Official record
Conditions
Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning, Chronic Medical Conditions, Chronic Medical Condition, Chronic Medical Illness, Posttraumatic Stress Disorder PTSD, Posttraumatic Stress Disorders, Posttraumatic Stress Symptoms, Posttraumatic Stress
Interventions
Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual, Structured Psychotherapy for Adolescents Responding to Chronic Stress - Individual
Behavioral
Lead sponsor
Anthony Vesco
Other
Eligibility
8 Years to 18 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Jul 23, 2026, 1:26 AM EDT
Completed No phase listed Observational

Assessing Costs & Cost-variability Among Enrollees of Health Insurance Programs Utilizing Charlson's Comorbidity Index and Administrative Databases

NCT01761253
View directory record Official record
Conditions
Multiple Chronic Illnesses
Interventions
Not listed
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
Not listed
Enrollment
241,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Feb 19, 2017 · Synced Jul 23, 2026, 1:26 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Heart Rate and Respiratory Rate Measurements by a Novel, Radar-based Device

NCT04796181
View directory record Official record
Conditions
Healthy Subjects, Chronic Conditions, Multiple
Interventions
Neteera 130H
Device
Lead sponsor
Neteera Technologies Ltd.
Industry
Eligibility
18 Years and older
Enrollment
170 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Millcreek, Utah
Source: ClinicalTrials.gov public record
Updated Oct 4, 2022 · Synced Jul 23, 2026, 1:26 AM EDT
Recruiting Phase 4 Interventional

LIVEBETTER: A Trial Comparing Medications in Older Adults With Stable Angina and Multiple Chronic Conditions

NCT05786417
View directory record Official record
Conditions
Angina, Stable Ischemic Heart Disease
Interventions
Clinician Discretion, Beta blocker, Calcium channel blocker
Other · Drug
Lead sponsor
Yale University
Other
Eligibility
65 Years and older
Enrollment
741 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
10
States / cities
New Haven, Connecticut • Marietta, Georgia • Chicago, Illinois + 5 more
Source: ClinicalTrials.gov public record
Updated Apr 6, 2026 · Synced Jul 23, 2026, 1:26 AM EDT