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Showing 25–48 of 248 matching trials from the live ClinicalTrials.gov search.
Completed Not applicable Interventional Accepts healthy volunteers Results available

Essential Amino Acids and Protein Kinetics During Caloric Deprivation

NCT03372928
Conditions
Muscle Protein Synthesis, Whole-body Protein Balance
Interventions
Standard EAA, High EAA
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Natick, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Heart and Muscle Metabolism in Barth Syndrome

NCT01625663
Conditions
Barth Syndrome
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
8 Years to 35 Years · Male only
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2020
U.S. locations
1
States / cities
St Louis, Missouri
Conditions
HIV, Obesity
Interventions
w-3 fatty acid, L-carnitine, Control Diet
Dietary Supplement · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
20 Years to 80 Years · Male only
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Conditions
Cachexia
Interventions
Deuterated Water, Testosterone enanthate, Placebo to match testosterone enanthate
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
60 Years to 75 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Durham, North Carolina
Conditions
Anterior Cruciate Ligament Reconstruction
Interventions
Neuromuscular electrical stimulation, Microstimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
18 Years to 50 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Recruiting No phase listed Observational Accepts healthy volunteers

Exercise Intolerance in Heart Failure

NCT03775577
Conditions
Heart Failure With Normal Ejection Fraction
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
21 Years and older
Enrollment
130 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2027
U.S. locations
1
States / cities
Baltimore, Maryland
Completed Not applicable Interventional Accepts healthy volunteers

Breakfast and Muscle Health in Children

NCT03602144
Conditions
Body Weight Changes, Body Composition, Muscle Mass, Energy Expenditure, Nutrition
Interventions
Carbohydrate, Protein
Other
Lead sponsor
University of Arkansas, Fayetteville
Other
Eligibility
7 Years to 14 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Fayetteville, Arkansas
Completed Not applicable Interventional Accepts healthy volunteers

Clinical Trial of Astaxanthin Formulation With Exercise in Sarcopenia Elderly

NCT03368872
Conditions
Sarcopenia
Interventions
Astaxanthin formulation, Placebo, Exercise training
Other
Lead sponsor
Astavita, Inc.
Industry
Eligibility
65 Years to 85 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
2
States / cities
Seattle, Washington
Conditions
Prostate Cancer
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
55 Years to 89 Years · Male only
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Dallas, Texas
Completed Not applicable Interventional Accepts healthy volunteers

Mechanisms of Skeletal Muscle Insulin Resistance in Older Adults

NCT02971098
Conditions
Reduced Physical Activity
Interventions
Reduced activity
Procedure
Lead sponsor
University of Utah
Other
Eligibility
60 Years to 85 Years
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Completed Not applicable Interventional Accepts healthy volunteers

Role of MicroRNAs on Age and Contraction-induced Skeletal Muscle Growth

NCT02638454
Conditions
Sarcopenia
Interventions
Acute Resistance Exercise
Procedure
Lead sponsor
Tufts University
Other
Eligibility
20 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Recruiting Not applicable Interventional Accepts healthy volunteers

Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease

NCT03622359
Conditions
Peripheral Artery Disease, Diabetes Mellitus, Chronic Limb-Threatening Ischemia
Interventions
SPECT/CT perfusion imaging, PET/CT perfusion imaging
Diagnostic Test
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
18 Years and older
Enrollment
192 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2028
U.S. locations
1
States / cities
Columbus, Ohio
Conditions
Prediabetic State
Interventions
Heat therapy, High-intensity interval training
Behavioral
Lead sponsor
Texas Tech University
Other
Eligibility
50 Years and older
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Lubbock, Texas
Withdrawn No phase listed Observational

Muscle Atrophy in Sepsis

NCT00583206
Conditions
Atrophy, Sepsis, Weakness
Interventions
Not listed
Lead sponsor
Gregory A. Schmidt
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Skeletal Muscle Disorder
Interventions
Blueberry enriched diet
Dietary Supplement
Lead sponsor
Cornell University
Other
Eligibility
21 Years to 79 Years · Female only
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Ithaca, New York
Completed Phase 2 Interventional Results available

(-)- Epicatechin Becker Muscular Dystrophy

NCT03236662
Conditions
Becker Muscular Dystrophy
Interventions
(-)-Epicatechin
Drug
Lead sponsor
Craig McDonald, MD
Other
Eligibility
18 Years to 70 Years · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Sacramento, California
Conditions
Atrophy, Disuse, Muscle Atrophy, Muscular Disorders, Atrophic, Disuse Atrophy, Disuse Atrophy Muscle of Thigh
Interventions
Unilateral leg immobilization, Contralateral active leg
Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 39 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Natick, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers

Measurement of NAD+ Synthesis in Human Skeletal Muscle

NCT04905446
Conditions
Skeletal Muscle
Interventions
Deuterated nicotinamide (D4-NAM) IV infusion, Skeletal muscle biopsy, Skin tissue biopsy
Other · Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
21 Years to 40 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Orlando, Florida
Conditions
HIV Infections, Fatigue, HIV Positive, AIDS, Healthy Volunteer, HV
Interventions
Not listed
Lead sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Eligibility
18 Years to 55 Years
Enrollment
82 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2014
U.S. locations
1
States / cities
Bethesda, Maryland
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Muscle Effects of GH in Boys

NCT04020913
Conditions
Growth Hormone Deficiency, Idiopathic Short Stature
Interventions
Somatropin injection
Drug
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
6 Years to 11 Years · Male only
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Jacksonville, Florida
Completed Phase 2 Interventional Results available

Nitrite Supplementation in Long COVID Patients

NCT05618574
Conditions
Long COVID, Cardiorespiratory Fitness
Interventions
140 ml per day of Beet-It nitrate beverage (James White Drinks Ltd., Ipswich, UK), 210 ml of nitrate-depleted placebo
Dietary Supplement
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Identification of Novel Skeletal Muscle-derived Factors That Promote Lipid Oxidation (Columbus)

NCT01911091
Conditions
Obesity, Disorder of Lipid Storage and Metabolism, Lipid Metabolism Disorders, Metabolic Disorder
Interventions
Exercise
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years to 40 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Conditions
Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia
Interventions
Exercise, Calls and Newsletter
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older · Male only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
San Francisco, California
Completed Not applicable Interventional Accepts healthy volunteers

Effects of PrimaVie and Exercise Training on Human Skeletal Muscle (PrimaVie)

NCT02026414
Conditions
Obesity
Interventions
PrimaVie, Exercise
Dietary Supplement · Other
Lead sponsor
Sanni Raju
Industry
Eligibility
21 Years to 70 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Columbus, Ohio