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ClinicalTrials.gov public records Last synced Oct 17, 2026, 9:28 AM EDT

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Showing 49–72 of 248 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle, Skeletal Clear all
Completed No phase listed Observational Accepts healthy volunteers

Characterization of Skeletal Muscle Using Magnetic Resonance Elastography (MRE)

NCT00588432
View directory record Official record
Conditions
Stroke, Immobilization, Myofacial Pain, Hyperthyroid Myopathy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2009 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Multi-Tracer PET Quantitation of Insulin Action in Muscle (Phase 1, Phase 2, Phase 3, Phase 4)

NCT00222885
View directory record Official record
Conditions
Diabetes, Obesity
Interventions
Not listed
Lead sponsor
University of Pittsburgh
Other
Eligibility
20 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2006
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 19, 2007 · Synced Oct 17, 2026, 9:28 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Improving Exercise Rehabilitation Efficacy Outcomes Veterans Peripheral Artery Disease

NCT05648630
View directory record Official record
Conditions
Peripheral Artery Disease (D058729), Oxidative Stress (D018384), Inflammation (D007249)
Interventions
PB125, Placebo, Exercise Rehabilitation
Dietary Supplement · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
40 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
2
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Increased, Egg-Based Protein Intake on Muscle Composition,

NCT01396915
View directory record Official record
Conditions
Muscle Composition, Sarcopenia, Hypertrophy, Inflammation
Interventions
Dietary Protein Intake
Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
55 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 4, 2016 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Training and Milk Supplementation

NCT04509297
View directory record Official record
Conditions
Muscular Hypertrophy
Interventions
high protein milk, Placebo
Dietary Supplement
Lead sponsor
Marymount University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Arlington, Virginia
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Oct 17, 2026, 9:28 AM EDT
Recruiting Phase 1 Interventional Accepts healthy volunteers

: Vascular Function in Health and Disease

NCT02966665
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Pulmonary Artery Hypertension, Heart Failure, Hypertension
Interventions
Maximum Exercise Tests, BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate, BQ-123, Fexofenadine, Ranitidine, Angiotensin-II, Valsartan, Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine, BQ-123, MitoQ, BH4
Other · Drug
Lead sponsor
D. Walter Wray
Other
Eligibility
18 Years and older
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2030
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACTIV- Exercise Intervention in Healthy Young Men

NCT00401791
View directory record Official record
Conditions
Insulin Resistance
Interventions
Exercise
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
25 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 21, 2022 · Synced Oct 17, 2026, 9:28 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Strength Training and Resveratrol

NCT06585865
View directory record Official record
Conditions
Sarcopenia, Anabolic Resistance
Interventions
Resistance training, Resveratrol 500 mg oral once daily., Placebo
Behavioral · Dietary Supplement
Lead sponsor
Texas Tech University
Other
Eligibility
60 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 17, 2026, 9:28 AM EDT
Terminated Phase 4 Interventional Results available

7T Magnetic Resonance Spectroscopy and Skeletal Muscle Biopsy Findings in Statin Associated Adverse Muscle Events

NCT04507373
View directory record Official record
Conditions
Muscle Cramp, Ache, Weakness, Muscle, Statin Adverse Reaction
Interventions
Simvastatin 40mg
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 14, 2023 · Synced Oct 17, 2026, 9:28 AM EDT
Terminated Early Phase 1 Interventional

A Pilot Study of Pyridostigmine in Pompe Disease

NCT02357225
View directory record Official record
Conditions
Pompe Disease
Interventions
Pyridostigmine Bromide
Drug
Lead sponsor
University of Florida
Other
Eligibility
8 Years to 60 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 17, 2026, 9:28 AM EDT
Recruiting Not applicable Interventional

Effects of Aerobic Exercise on Skeletal Muscle Remodeling in Colorectal Cancer

NCT05789433
View directory record Official record
Conditions
Colonic Neoplasms, Rectal Neoplasms
Interventions
Aerobic exercise, Progressive stretching
Behavioral
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 3, 2025 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Meal Patterning on Weight Loss With Changes to Body Comp, Muscle and Metabolic Health

NCT02066948
View directory record Official record
Conditions
Body Composition, Beneficial, Paresis, Impaired Glucose Tolerance
Interventions
wt loss, meal pattern, even, skew
Other · Dietary Supplement
Lead sponsor
Purdue University
Other
Eligibility
19 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 1, 2017 · Synced Oct 17, 2026, 9:28 AM EDT
Recruiting Not applicable Interventional

Prebiotic Inulin for Late-Reproductive Individuals

NCT07724522
View directory record Official record
Conditions
Obesity & Overweight, Perimenopausal Women, Prebiotics, Inulin, Muscle, Skeletal, Cardiovascular Diseases (CVD), Microbiota, Gastrointestinal Microbiome, Dietary Fiber, Women Health, Vascular Health, Insulin Resistance
Interventions
Inulin, Maltodextrin (Placebo)
Dietary Supplement
Lead sponsor
George Washington University
Other
Eligibility
40 Years to 55 Years · Female only
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Skeletal Muscle Properties and the Metabolic Cost of Walking Post-stroke

NCT00721357
View directory record Official record
Conditions
Stroke
Interventions
Treadmill walking, Magnetic resonance spectroscopy
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2013
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2019 · Synced Oct 17, 2026, 9:28 AM EDT
Not yet recruiting Phase 1 Interventional

A Study to Learn About the Study Medicine Called Ponsegromab in Adults With Lung Cancer-Associated Significant Body Weight Loss

NCT07663630
View directory record Official record
Conditions
Non-small Cell Lung Cancer (NSCLC), Cachexia
Interventions
ponsegromab, placebo
Drug
Lead sponsor
Pfizer
Industry
Eligibility
18 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
6
States / cities
Decatur, Illinois • O'Fallon, Illinois • Garland, Texas + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational

Studying Skeletal Muscle, Heart, and Diaphragm Imaging in Boys With Duchenne Muscular Dystrophy

NCT01451281
View directory record Official record
Conditions
Muscular Dystrophy, Muscular Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
5 Years to 17 Years · Male only
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2019
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated May 22, 2019 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational

DNA/RNA Analysis of Blood and Skeletal Muscle in Patients Undergoing Cardiac Resynchronization Therapy (CRT)

NCT00600392
View directory record Official record
Conditions
Cardiomyopathy (Ischemic or Non-Ischemic)
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
18 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 20, 2016 · Synced Oct 17, 2026, 9:28 AM EDT
Terminated Phase 2 Interventional Results available

The Effect of Nicotinamide Riboside on Skeletal Muscle Function in Heart Failure Subjects

NCT03565328
View directory record Official record
Conditions
Heart Failure
Interventions
Nicotinamide Riboside
Dietary Supplement
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
2
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 28, 2020 · Synced Oct 17, 2026, 9:28 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Physical Inactivity and Insulin Resistance in Skeletal Muscle.

NCT00536211
View directory record Official record
Conditions
Metabolic Syndrome X, Insulin Resistance, Hypertension, Hypercholesterolemia, Obesity
Interventions
Exercise, Metformin
Behavioral · Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
20 Years to 55 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated May 4, 2021 · Synced Oct 17, 2026, 9:28 AM EDT
Active, not recruiting Phase 2 Interventional

Evolutionary Therapy for Rhabdomyosarcoma

NCT04388839
View directory record Official record
Conditions
Rhabdomyosarcoma
Interventions
Vincristine, Cyclophosphamide, Vinorelbine, Actinomycin D, Cyclophosphamide Pill
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
18
States / cities
Birmingham, Alabama • Aurora, Colorado • Hartford, Connecticut + 15 more
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Blood and Muscle Response to Cheddar Cheese in Healthy Adults

NCT04660877
View directory record Official record
Conditions
Healthy
Interventions
Cheddar Cheese, Milk
Dietary Supplement
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 35 Years
Enrollment
42 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jun 22, 2022 · Synced Oct 17, 2026, 9:28 AM EDT
Completed No phase listed Observational

Biological Markers in Patients With Pancreatic Cancer Experiencing Weight Loss

NCT00899158
View directory record Official record
Conditions
Cachexia, Pancreatic Cancer
Interventions
immunologic technique, laboratory biomarker analysis, biopsy
Other · Procedure
Lead sponsor
Case Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2008
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 30, 2015 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Effects of Strength Training on Knee Osteoarthritis

NCT00000406
View directory record Official record
Conditions
Osteoarthritis, Knee
Interventions
Progressive resistance exercise
Procedure
Lead sponsor
Indiana University
Other
Eligibility
60 Years and older
Enrollment
280 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1977 – 2006
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 30, 2013 · Synced Oct 17, 2026, 9:28 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Impact of Diet on the Gut-Muscle Axis in Older Adults

NCT05549622
View directory record Official record
Conditions
Sarcopenia, Dietary Exposure, Microbial Colonization
Interventions
Low-soluble fiber diet, High-soluble fiber diet
Other
Lead sponsor
Tufts University
Other
Eligibility
65 Years and older
Enrollment
31 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 18, 2025 · Synced Oct 17, 2026, 9:28 AM EDT