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ClinicalTrials.gov public records Last synced Oct 17, 2026, 1:36 PM EDT

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Showing 121–144 of 248 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle, Skeletal Clear all
Terminated Not applicable Interventional

Exercise Intolerance and Skeletal Muscle Bioenergetics in Children With Deep Venous Thrombosis

NCT04294849
View directory record Official record
Conditions
Deep Vein Thrombosis, Pulmonary Embolism
Interventions
Magnetic Resonance Imaging, Bicycle Ergometry, Lab Panel, Questionnaires
Other · Behavioral
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
8 Years to 21 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 17, 2026, 1:36 PM EDT
Withdrawn Not applicable Interventional

Isoleucine Addition Treatment Effects in a Controlled Diet Study

NCT07329088
View directory record Official record
Conditions
Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Metabolic Syndrome (MetS), Obesity & Overweight
Interventions
L-Isoleucine, Low-isoleucine diet
Dietary Supplement · Other
Lead sponsor
Jean L. Fry
Other
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skeletal Muscle Protein Synthesis: Traditional and Cluster Sets

NCT04028726
View directory record Official record
Conditions
Resistance Exercise
Interventions
Back-squat exercise
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 24, 2019 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Beef Consumption on Skeletal Muscle Protein Homeostasis and Inflammatory Factors in Pre- and Postmenopausal Females

NCT05714462
View directory record Official record
Conditions
Menopause Related Conditions
Interventions
meals consisting of primarily animal protein sources, meals consisting of plant protein sources
Other
Lead sponsor
University of Arkansas
Other
Eligibility
35 Years to 65 Years · Female only
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 6, 2025 · Synced Oct 17, 2026, 1:36 PM EDT
Not listed Not applicable Interventional

Flywheel Exercise for CKD

NCT03582982
View directory record Official record
Conditions
Chronic Kidney Disease stage3, Chronic Kidney Disease stage4
Interventions
Eccentric overload exercise
Behavioral
Lead sponsor
Washington D.C. Veterans Affairs Medical Center
Federal
Eligibility
18 Years to 84 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Nov 9, 2018 · Synced Oct 17, 2026, 1:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Effects of Graded Protein Intake on Body Composition in Older Adults

NCT04845282
View directory record Official record
Conditions
Sarcopenia
Interventions
Graded Protein plus Resistance Training, RDA Protein plus Resistance Training
Dietary Supplement
Lead sponsor
Wake Forest University
Other
Eligibility
55 Years to 110 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 27, 2022 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Potential Synergistic Effect of Combined Blood Flow Restriction Training and Betaine Supplementation on Skeletal Muscle

NCT05790070
View directory record Official record
Conditions
Blood Flow Restriction Training, Betaine Supplementation
Interventions
Betaine, Placebo
Dietary Supplement · Other
Lead sponsor
Baylor University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Waco, Texas
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Musculoskeletal Plasticity After Spinal Cord Injury

NCT02622295
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Single-session electrically induced exercise, Electrically-induced exercise training
Behavioral
Lead sponsor
Richard K Shields
Other
Eligibility
21 Years to 60 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 4, 2022 · Synced Oct 17, 2026, 1:36 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Dynamic in Vivo PET Imaging and ex Vivo Biopsies From Skeletal Muscle and Adipose Tissue to Investigate the Effects of Exercise on Insulin Resistance and Mitochondrial Energetics in Type 2 Diabetes

NCT04754581
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
Maximal ATP Production (ATPmax), Exercise Testing (VO2max), Muscle Biopsy, Adipose Tissue Biopsy, Hyperinsulinemic euglycemic clamp, PET imaging
Other · Procedure
Lead sponsor
AdventHealth Translational Research Institute
Other
Eligibility
30 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Phase 1Phase 2 Interventional Results available

Use of (-)-Epicatechin in the Treatment of Becker Muscular Dystrophy (Pilot Study)

NCT01856868
View directory record Official record
Conditions
Becker Muscular Dystrophy
Interventions
(-)-epicatechin
Drug
Lead sponsor
Craig McDonald, MD
Other
Eligibility
18 Years to 60 Years · Male only
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Dec 22, 2021 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

NCT02739620
View directory record Official record
Conditions
Breast Cancer
Interventions
Neuromuscular electrical stimulation
Device
Lead sponsor
University of Vermont
Other
Eligibility
40 Years to 70 Years · Female only
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Apr 11, 2023 · Synced Oct 17, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

NCT05356117
View directory record Official record
Conditions
Pancreatic Cancer
Interventions
Resistance Training (RT) and Protein Supplementation (PS), Resistance Training (RT), Attention Control (AC
Behavioral
Lead sponsor
Dana-Farber Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 19, 2026 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional

Blood Flow Restriction Exercise for Those With SCI

NCT04889092
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Blood Flow Restriction exercise, Traditional resistance exercise
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 27, 2024 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Role of Flavanols in Exercise and Aging

NCT01557738
View directory record Official record
Conditions
Aging
Interventions
High Flavanol Trial, Low Flavanol Trial, High Flavanol Trial; long-term, Low Flavanol Trial; long-term effects
Dietary Supplement
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 80 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 25, 2014 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Resistance Exercise and Low-Intensity Physical Activity Breaks in Sedentary Time to Improve Muscle and Cardiometabolic Health

NCT03771417
View directory record Official record
Conditions
Aging, Sarcopenia, Disability Physical, Cardiovascular Diseases, Insulin Resistance, Diabetes Mellitus
Interventions
Exercise Intervention
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
65 Years to 80 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
2
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Exercise Dose Response for Improving Insulin Sensitivity

NCT01452035
View directory record Official record
Conditions
Obesity
Interventions
Exercise
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 8, 2016 · Synced Oct 17, 2026, 1:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle

NCT01644279
View directory record Official record
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
20 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 3, 2016 · Synced Oct 17, 2026, 1:36 PM EDT
Terminated Phase 1 Interventional

A Study to Assess the Anti-fatigability Effect of CK-2127107 in Elderly Male and Female Subjects With Limitations in Mobility

NCT03065959
View directory record Official record
Conditions
Mobility Limitation
Interventions
reldesemtiv, Placebo
Drug
Lead sponsor
Astellas Pharma Global Development, Inc.
Industry
Eligibility
65 Years to 89 Years
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
5
States / cities
Gainesville, Florida • Boston, Massachusetts • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 31, 2024 · Synced Oct 17, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Dietary Nitrate on Immobilization-induced Changes in Skeletal Muscle in Young Healthy Men

NCT07161973
View directory record Official record
Conditions
Mitochondrial Energetics, Dietary Nitrate, Disuse Atrophy (Muscle) of Lower Leg
Interventions
Beetroot Juice - Active, Placebo Beetroot Juice Without Nitrate
Dietary Supplement
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 44 Years · Male only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 17, 2026, 1:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Insulin Action: Role of Skeletal Muscle and Insulin-Mediated Blood Flow

NCT00018304
View directory record Official record
Conditions
Hypertension
Interventions
Not listed
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
50 Years to 75 Years
Healthy volunteers
Accepts healthy volunteers
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 21, 2009 · Synced Oct 17, 2026, 1:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

The Impact of Biological Mechanisms of Aging on Response Variability to Resistance Training in Older Adults

NCT06940037
View directory record Official record
Conditions
Aging, Mobility Disability
Interventions
Progressive Resistance Training, Health Education
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 17, 2026, 1:36 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Mitochondrial Respiratory Function in Mammalian Skeletal Muscle

NCT02650570
View directory record Official record
Conditions
Cancer, Cachexia
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
30 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 17, 2026, 1:36 PM EDT
Withdrawn Not applicable Interventional

Musculotendinous Tissue Unit Repair and Reinforcement (MTURR) Coordinating Center

NCT01497678
View directory record Official record
Conditions
Traumatic Injury, Muscle Injury, Tendon Injury, Soft Tissue Injury, Extremity Injury
Interventions
Extracellular Matrix
Device
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 70 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 21, 2016 · Synced Oct 17, 2026, 1:36 PM EDT
Completed Not applicable Interventional Results available

Exercise to Prevent Muscle Mass and Functional Loss in Elderly Dialysis Patients

NCT01990495
View directory record Official record
Conditions
Chronic Kidney Disease
Interventions
Exercise training, Usual Care
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
55 Years to 80 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 25, 2021 · Synced Oct 17, 2026, 1:36 PM EDT