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ClinicalTrials.gov public records Last synced Jun 26, 2026, 5:36 PM EDT

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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Muscle Activation Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Muscle Activation With Acute Bouts of Blood Flow Restricted Resistance Exercise

NCT05586451
View directory record Official record
Conditions
Muscle, Acute Exercise
Interventions
Traditional High Load Resistance Exercise (HLRE), Low Load Resistance Exercise with Blood Flow Restriction (LLBFR), Moderate Load Resistance Exercise with Blood Flow Restriction (MLBFR)
Behavioral
Lead sponsor
Louisiana State University and A&M College
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 12, 2023 · Synced Jun 26, 2026, 5:36 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Acute Effects of Alpha-glycerylphosphorylcholine (A-GPC) on Lower Body Muscular Performance.

NCT07397273
View directory record Official record
Conditions
Healthy Adult Participants
Interventions
L-Alpha glycerylphosphorylcholine, Microcrystalline Cellulose
Dietary Supplement
Lead sponsor
Northern Illinois University
Other
Eligibility
19 Years to 29 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
DeKalb, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 8, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Perception of Electrical Stimuli in Individuals With Stroke

NCT05465005
View directory record Official record
Conditions
Stroke
Interventions
Torque Generation
Behavioral
Lead sponsor
Netta Gurari
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2028
U.S. locations
1
States / cities
Blacksburg, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Phase 2 Interventional Results available

Early Neuromuscular Electrical Stimulation For Quadriceps Muscle Activation Deficits Following Total Knee Replacement

NCT00800254
View directory record Official record
Conditions
Osteoarthritis
Interventions
Neuromuscular Electrical Stimulation (NMES), Standard Rehabilitation Protocol
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years to 85 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Aug 10, 2015 · Synced Jun 26, 2026, 5:36 PM EDT
Recruiting Not applicable Interventional

Targeting Cervical Epidural Spinal Cord Stimulation for Functional Recovery

NCT06701422
View directory record Official record
Conditions
Cervical Spinal Cord Injury, Tetraplegia/Tetraparesis, Cervical Myelopathy
Interventions
Intraoperative stimulation of the cervical spinal cord
Procedure
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jun 26, 2026, 5:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Rate of Torque Development and Voluntary Quadriceps Activation in Patients With Knee Osteoarthritis: A Quantitative Analysis Before and After a Single Session of Manual Physical Therapy

NCT04234282
View directory record Official record
Conditions
Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic, Knee Deformity, Knee Pain Swelling, Muscle Weakness, Muscle Weakness Condition, Power
Interventions
Manual Physical Therapy
Procedure
Lead sponsor
Jennifer Moreno Clinic
Other
Eligibility
45 Years to 74 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Fort Sam Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 20, 2020 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional Results available

Altering Activation Patterns Post-stroke

NCT02418949
View directory record Official record
Conditions
Stroke, Muscle Spasticity, Hemiparesis
Interventions
Cyproheptadine, Placebo for Cyproheptadine, Active Movement Practice (AMP), Passive Cyclical Stretching
Drug · Other
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
18 Years to 80 Years
Enrollment
96 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Active, not recruiting Phase 1Phase 2 Interventional

Safety and Preliminary Anti-Tumor Activity of TYRA-300 in Advanced Urothelial Carcinoma and Other Solid Tumors With FGFR3 Gene Alterations

NCT05544552
View directory record Official record
Conditions
Locally Advanced Urothelial Carcinoma, Metastatic Urothelial Carcinoma, Solid Tumor, Urothelial Carcinoma, Solid Tumor, Adult, Bladder Cancer, Non-muscle-invasive Bladder Cancer, FGFR3 Gene Mutation, FGFR3 Gene Alteration, Advanced Solid Tumor, Advanced Urothelial Carcinoma, Urinary Tract Cancer, Urinary Tract Tumor, Urinary Tract Carcinoma
Interventions
TYRA-300
Drug
Lead sponsor
Tyra Biosciences, Inc
Industry
Eligibility
18 Years and older
Enrollment
310 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
7
States / cities
Boston, Massachusetts • Worchester, Massachusetts • New York, New York + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 11, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place

NCT03853148
View directory record Official record
Conditions
Pain, Chronic, Fatigue Syndrome, Chronic, Aging
Interventions
Otago, Gentle yogic breathing, Behavioral Activation, Caregiver Gentle yogic breathing
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
45 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 28, 2022 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Evaluation of Muscle Activation Efficiency in Challenging Subjects

NCT01811446
View directory record Official record
Conditions
Obesity, COPD
Interventions
Muscle Activation with Niveus and Intelect Devices
Device
Lead sponsor
Niveus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jan 30, 2014 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional

PCMS Task After Moderate-to-severe Stroke

NCT05736653
View directory record Official record
Conditions
Stroke
Interventions
Task-specific PCMS, Task-specific sham-PCMS, PCMS-rest
Device
Lead sponsor
University of Utah
Other
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Recruiting No phase listed Observational

Wearable Sensors to Detect Atypical Muscle Activation in Young Infants

NCT06970522
View directory record Official record
Conditions
Neuromuscular Disorders, Motor Development, Muscle Tone
Interventions
Not listed
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
0 Months to 8 Weeks
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Phase 1 Interventional Results available

Phase I Study of LDK378 in Pediatric, Malignancies With a Genetic Alteration in Anaplastic Lymphoma Kinase (ALK)

NCT01742286
View directory record Official record
Conditions
ALK-activated Tumors
Interventions
Ceritinib
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
12 Months to 17 Years
Enrollment
83 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
5
States / cities
Boston, Massachusetts • New York, New York • Cincinnati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2020 · Synced Jun 26, 2026, 5:36 PM EDT
Recruiting Not applicable Interventional

The Influence of Movement Velocity Biofeedback on Muscle Activation and Self Perception in Older Adults With Sarcopenia

NCT06853275
View directory record Official record
Conditions
Sarcopenia, Sarcopenia in Elderly, Age-associated Muscle Loss
Interventions
Experimental: External Focus, Other: Internal Focus
Behavioral
Lead sponsor
Creighton University
Other
Eligibility
60 Years to 95 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Comparing Intact and Residual Amputated Muscle

NCT06182202
View directory record Official record
Conditions
Amputation
Interventions
Powered Prosthesis
Device
Lead sponsor
North Carolina State University
Other
Eligibility
18 Years to 64 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Raleigh, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 25, 2023 · Synced Jun 26, 2026, 5:36 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Muscle Activation Characteristics During Spinal Manipulation in Healthy and Low Back Pain Participants

NCT03483714
View directory record Official record
Conditions
Back Pain
Interventions
Spinal Manipulation
Procedure
Lead sponsor
University of Denver
Other
Eligibility
18 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Mar 29, 2018 · Synced Jun 26, 2026, 5:36 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effects of Torso Weighting on Muscle Activation During Balance Tests in Individuals With and Without Multiple Sclerosis

NCT06981013
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
balance based torso weighting
Other
Lead sponsor
University of St. Augustine for Health Sciences
Other
Eligibility
18 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Saint Augustine, Florida
Source: ClinicalTrials.gov public record
Updated May 19, 2025 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Cervical Multifidus Muscle Function

NCT00733837
View directory record Official record
Conditions
Proprioception, Muscle Activation
Interventions
Nonspecific, Innocuous, Mechanoreceptor Stimulation
Other
Lead sponsor
Logan College of Chiropractic
Other
Eligibility
18 Years to 30 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008
U.S. locations
1
States / cities
Chesterfield, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 17, 2008 · Synced Jun 26, 2026, 5:36 PM EDT
Enrolling by invitation Not applicable Interventional

Comparison of Dynamic Ultrasound Visual Feedback to Manual Feedback on Scapular Stabilizer Activation and Change in the Subacromial Space in Persons With Pain During Shoulder Elevation

NCT07464639
View directory record Official record
Conditions
Subacromial Impingement Syndrome, Apical Shoulder Pain, Rotator Cuff Syndrome
Interventions
Verbal and tactile feedback with exercise
Other
Lead sponsor
California State University, Long Beach
Other
Eligibility
18 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Long Beach, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

ACTIV- Exercise Intervention in Healthy Young Men

NCT00401791
View directory record Official record
Conditions
Insulin Resistance
Interventions
Exercise
Behavioral
Lead sponsor
Pennington Biomedical Research Center
Other
Eligibility
25 Years to 35 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Baton Rouge, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 20, 2022 · Synced Jun 26, 2026, 5:36 PM EDT
Terminated Not applicable Interventional

PB125, Osteoarthritis, Pain, Mobility, and Energetics

NCT04638387
View directory record Official record
Conditions
Osteoarthritis, Knee, Muscle Weakness, Pain, Joint
Interventions
PB125, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
50 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Jun 26, 2026, 5:36 PM EDT
Active, not recruiting Not applicable Interventional

Activating Spinal Circuits to Improve Walking, Balance, Strength, and Reduce Spasticity

NCT05429736
View directory record Official record
Conditions
Incomplete Spinal Cord Injury, Spasticity, Muscle
Interventions
Motor Skill Training (MST), Transcutaneous Spinal Stimulation (TSS)
Behavioral · Device
Lead sponsor
Shepherd Center, Atlanta GA
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Prior Muscle Activation on the Compound Muscle Action Potential (CMAP)

NCT01182558
View directory record Official record
Conditions
Focus: Effect of Muscle Activation on CMAP in Normal Humans
Interventions
Hypothenar muscle activation--maximum, voluntary, isometric, Thenar muscle activation--maximum, voluntary, isometric, EDB muscle activation--maximum, voluntary, isometric, Relaxation of muscle
Other
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years to 49 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2019
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Aug 13, 2019 · Synced Jun 26, 2026, 5:36 PM EDT
Completed Not applicable Interventional

Conditioning Brain Responses to Improve Thigh Muscle Function After Anterior Cruciate Ligament Reconstruction

NCT03209531
View directory record Official record
Conditions
Anterior Cruciate Ligament Injury
Interventions
Operant Conditioning, Control, Single Pulse Transcranial Magnetic Stimulation
Behavioral · Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 45 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2025
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 25, 2025 · Synced Jun 26, 2026, 5:36 PM EDT