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Showing 1–24 of 115 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Muscle Damage Clear all
Completed Phase 2 Interventional Accepts healthy volunteers

The Effects of Probiotic Supplementation on Markers of Muscle Damage and Performance Following Exercise Induced Muscle Damage

NCT02520583
View directory record Official record
Conditions
Probiotics
Interventions
Lactic acid bacteria and bifidobacteria, Placebo
Dietary Supplement · Other
Lead sponsor
Texas Christian University
Other
Eligibility
18 Years to 35 Years · Male only
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Oct 18, 2016 · Synced Jun 26, 2026, 10:43 AM EDT
Withdrawn Early Phase 1 Interventional Accepts healthy volunteers

Topical Cannabidiol Cream and Post-exercise Recovery

NCT05044936
View directory record Official record
Conditions
Muscle Damage
Interventions
Cannabidiol Oil, Resistance Exercise
Drug · Other
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 35 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated May 16, 2023 · Synced Jun 26, 2026, 10:43 AM EDT
Recruiting Phase 4 Interventional

Ramipril Treatment of Claudication: Oxidative Damage and Muscle Fibrosis

NCT02842424
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Ramipril
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
18 Years to 90 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 22, 2025 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Quadriceps Muscle Plasticity in Children With Cerebral Palsy

NCT00629070
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Traditional strength training, Velocity-enhanced training
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
7 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 16, 2018 · Synced Jun 26, 2026, 10:43 AM EDT
Recruiting No phase listed Observational

Toward Ubiquitous Lower Limb Exoskeleton Use in Children and Young Adults

NCT06998134
View directory record Official record
Conditions
Muscle Weakness, Problems Moving Their Arms and Legs
Interventions
Extension assist knee ankle foot orthosis (EA-KAFO)
Device
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
5 Years to 25 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Phase 3 Interventional Results available

BOTOX® Treatment in Pediatric Lower Limb Spasticity

NCT01603628
View directory record Official record
Conditions
Pediatrics, Muscle Spasticity, Cerebral Palsy
Interventions
botulinum toxin Type A, Normal Saline (Placebo)
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
2 Years to 16 Years
Enrollment
384 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
24
States / cities
Pasadena, California • Pomona, California • Aurora, Colorado + 19 more
Source: ClinicalTrials.gov public record
Updated Aug 13, 2018 · Synced Jun 26, 2026, 10:43 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Transitioning to a Valve-Gated Intrathecal Drug Delivery System (IDDS)

NCT04530955
View directory record Official record
Conditions
Injuries, Spinal Cord, CVA (Cerebrovascular Accident), Traumatic Brain Injury, MS (Multiple Sclerosis), Muscle Spasticity, Cerebral Palsy, Spastic
Interventions
Prometra II Programmable Pump - Flowonix Medical
Device
Lead sponsor
Culicchia Neurological Clinic
Other
Eligibility
22 Years to 85 Years
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marrero, Louisiana
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Astaxanthin, Exercise Inflammation, Skin Health

NCT05409092
View directory record Official record
Conditions
Inflammatory Response, Metabolic Disturbance, Immune Suppression
Interventions
Astaxanthin, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 57 Years
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Pea Proteins on Muscle Damage and Recovery

NCT05657314
View directory record Official record
Conditions
Pea Proteins, Muscle Damage, Amino Acid Change
Interventions
Active Comparator
Dietary Supplement
Lead sponsor
The Center for Applied Health Sciences, LLC
Industry
Eligibility
18 Years to 55 Years · Male only
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Canfield, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 19, 2022 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Long-term Effects of Oceanix™ on Resistance Training Adaptations

NCT04136821
View directory record Official record
Conditions
Oxidative Stress, Muscle Strength, Resistance Training, Body Composition, Muscle Damage
Interventions
Oceanix, Resistance Training
Dietary Supplement · Other
Lead sponsor
Applied Science & Performance Institute
Industry
Eligibility
18 Years to 45 Years
Enrollment
25 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 26, 2020 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cranberry Ingestion and Cycling Related Immunity and Inflammation

NCT05407701
View directory record Official record
Conditions
Inflammatory Response, Metabolic Disturbance, Immune Suppression
Interventions
Cranberry Juice, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
18 Years to 55 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jun 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Resveratrol Supplementation on Exercise Performance and Recovery

NCT06723119
View directory record Official record
Conditions
Effect of Resveratrol on Performance and Recovery
Interventions
Resveratrol (VRES) 500 mg oral once daily., Placebo 500 mg oral once daily.
Other
Lead sponsor
University of Central Florida
Other
Eligibility
18 Years to 40 Years · Male only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Results available

Study Assessing High-Frequency Chest Wall Oscillation (HFCWO) in Preventing Pulmonary Exacerbations

NCT00739310
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Vest Treatment (high frequency chest wall oscillation)
Device
Lead sponsor
Hill-Rom
Industry
Eligibility
18 Months to 18 Years
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Brooklyn, New York
Source: ClinicalTrials.gov public record
Updated Aug 6, 2017 · Synced Jun 26, 2026, 10:43 AM EDT
Terminated Phase 2Phase 3 Interventional Results available

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

NCT04815967
View directory record Official record
Conditions
Spasticity, Cerebrovascular Accident, Multiple Sclerosis, Traumatic Brain Injury, Cervical Spinal Cord Injury, Cerebral Palsy
Interventions
Phase 2; Low Dose MYOBLOC (10,000 Units), Phase 2; High Dose MYOBLOC (20,000 Units), Phase 2; Placebo, Phase 3; MYOBLOC, Phase 3; Placebo
Drug
Lead sponsor
Solstice Neurosciences, LLC, a subsidiary of MDD US Operations, LLC
Industry
Eligibility
18 Years to 80 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
4
States / cities
Downey, California • Boise, Idaho • Port Royal, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated May 26, 2026 · Synced Jun 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

NCT06070233
View directory record Official record
Conditions
Spasticity as Sequela of Stroke, Spastic Cerebral Palsy, Spasticity, Muscle
Interventions
stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation, Sham
Radiation · Other
Lead sponsor
Ohio State University
Other
Eligibility
16 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
2
States / cities
Winter Park, Florida • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein and Recovery From Exercise-induced Muscle Damage

NCT02034721
View directory record Official record
Conditions
Muscle Damage, Inflammation
Interventions
Protein supplement, Placebo
Dietary Supplement
Lead sponsor
Appalachian State University
Other
Eligibility
Male only
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2014
U.S. locations
1
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 12, 2016 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vitamin D2, Muscle Damage, NASCAR Pitcrew

NCT01825616
View directory record Official record
Conditions
Muscle Function, Muscle Soreness, Vitamin D Status
Interventions
Vitamin D2 mushroom powder, Placebo
Dietary Supplement · Other
Lead sponsor
Appalachian State University
Other
Eligibility
20 Years to 40 Years · Male only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
3
States / cities
Kannapolis, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 8, 2013 · Synced Jun 26, 2026, 10:43 AM EDT
Recruiting Not applicable Interventional

Intrathecal Baclofen and Pediatric Dystonia

NCT06606574
View directory record Official record
Conditions
Dystonic Cerebral Palsy
Interventions
Titration protocol
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Up to 17 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional

A Randomized Exercise Trial for Wheelchair Users

NCT00866112
View directory record Official record
Conditions
Spinal Cord Injury, Multiple Sclerosis, Muscular Dystrophy, Cerebral Palsy, Spina Bifida, Amputation, Arthritis, Stroke
Interventions
Educational session to promote physical activity, Minimal contact
Other
Lead sponsor
University of Kansas
Other
Eligibility
18 Years to 65 Years
Enrollment
135 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2012
U.S. locations
1
States / cities
Lawrence, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 14, 2012 · Synced Jun 26, 2026, 10:43 AM EDT
Active, not recruiting Not applicable Interventional

Short-Burst Interval Treadmill Training Cerebral Palsy

NCT04026295
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Short Burst Interval Treadmill Training (SBLTT), Traditional Locomotor Treadmill Training (TLTT)
Behavioral
Lead sponsor
Kristie Bjornson
Other
Eligibility
6 Years to 10 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
New Orleans, Louisiana • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jul 29, 2025 · Synced Jun 26, 2026, 10:43 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Skeletal Muscle Apoptosis and Physical Performance; Oxidative RNA/DNA Damage and Repair in Aged Human Muscle

NCT01644279
View directory record Official record
Conditions
Sarcopenia
Interventions
Not listed
Lead sponsor
University of Florida
Other
Eligibility
20 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 2, 2016 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Not applicable Interventional

Mechanisms That Produce the Leg Dysfunction of Claudication & Treatment Strategies

NCT01970332
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Revascularization Surgery, Supervised exercise therapy
Procedure · Other
Lead sponsor
University of Nebraska
Other
Eligibility
Not listed
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2016
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Jun 26, 2026, 10:43 AM EDT
Completed Phase 3 Interventional Results available

Dysport® Pediatric Lower Limb Spasticity Follow-on Study

NCT01251380
View directory record Official record
Conditions
Cerebral Palsy, Muscle Spasticity, Children
Interventions
Botulinum toxin type A
Biological
Lead sponsor
Ipsen
Industry
Eligibility
2 Years to 17 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
8
States / cities
Aurora, Colorado • Chicago, Illinois • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 27, 2022 · Synced Jun 26, 2026, 10:43 AM EDT
Not listed Phase 2 Interventional Accepts healthy volunteers

Outcomes Mandate National Integration With Cannabis as Medicine

NCT03944447
View directory record Official record
Conditions
Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma, Fibromyalgia, Seizures, Hepatitis C, Cancer, Crohn Disease, HIV/AIDS, Multiple Sclerosis, Traumatic Brain Injury, Sickle Cell Disease, Post Traumatic Stress Disorder, Tourette Syndrome, Ulcerative Colitis, Glaucoma, Epilepsy, Inflammatory Bowel Diseases, Parkinson Disease, Amyotrophic Lateral Sclerosis, Chronic Traumatic Encephalopathy, Anxiety, Depression, Insomnia, Autism, Opioid-use Disorder, Bipolar Disorder, Covid19, SARS-CoV Infection, COVID-19, Corona Virus Infection, Coronavirus
Interventions
Cannabis, Medical, RYAH-Medtech Inhaler
Drug · Device
Lead sponsor
OMNI Medical Services, LLC
Network
Eligibility
7 Years and older
Enrollment
200,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2025
U.S. locations
17
States / cities
Boca Raton, Florida • Bradenton, Florida • Fort Lauderdale, Florida + 13 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2022 · Synced Jun 26, 2026, 10:43 AM EDT