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ClinicalTrials.gov public records Last synced Nov 6, 2026, 10:03 AM EST

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Showing 1201–1224 of 3,714 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle Disorders Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Nitric Oxide Production in MELAS Syndrome

NCT01339494
View directory record Official record
Conditions
MELAS Syndrome
Interventions
Arginine and citrulline supplementations
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 5, 2016 · Synced Nov 6, 2026, 10:03 AM EST
Recruiting Phase 2 Interventional

Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD

NCT07435129
View directory record Official record
Conditions
Facioscapulohumeral Muscular Dystrophy, FSHD
Interventions
Apitegromab, Placebo
Drug
Lead sponsor
Scholar Rock, Inc.
Industry
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 1Phase 2 Interventional Results available

Evaluate Safety and Biological Activity of ATYR1940 in Participants With Limb Girdle Muscular Dystrophy 2B (LGMD2B) and Facioscapulohumeral Muscular Dystrophy (FSHD)

NCT02579239
View directory record Official record
Conditions
Limb-Girdle Muscular Dystrophies, Facioscapulohumeral Muscular Dystrophy
Interventions
ATYR1940, Placebo
Biological
Lead sponsor
aTyr Pharma, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Irvine, California • Baltimore, Maryland • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Oct 19, 2023 · Synced Nov 6, 2026, 10:03 AM EST
Recruiting No phase listed Observational

Clinical Trial Readiness for the Dystroglycanopathies

NCT00313677
View directory record Official record
Conditions
Muscular Dystrophy
Interventions
Not listed
Lead sponsor
Katherine Mathews
Other
Eligibility
Not listed
Enrollment
190 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2030
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Nov 6, 2026, 10:03 AM EST
Recruiting No phase listed Observational

Imaging Genetics of Laryngeal Dystonia

NCT03042975
View directory record Official record
Conditions
Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients, Voice Tremor, Muscle Tension Dysphonia
Interventions
MRI, Blood draw
Other · Procedure
Lead sponsor
Kristina Simonyan
Other
Eligibility
Not listed
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 2, 2025 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 3 Interventional Results available

BOTOX® Treatment in Adult Patients With Post-Stroke Lower Limb Spasticity

NCT01575054
View directory record Official record
Conditions
Muscle Spasticity
Interventions
botulinum toxin Type A, Normal Saline
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
18 Years to 85 Years
Enrollment
468 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2015
U.S. locations
2
States / cities
Downey, California • Daytona Beach, Florida
Source: ClinicalTrials.gov public record
Updated Sep 28, 2016 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Trigger Finger Corticosteroid Injection With and Without Local Anesthetic

NCT04023695
View directory record Official record
Conditions
Trigger Finger
Interventions
Corticosteroid with lidocaine with epinephrine, Corticosteroid with normal saline
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Dec 18, 2019 · Synced Nov 6, 2026, 10:03 AM EST
Terminated Not applicable Interventional Results available

Studying Changes in Physical Function Measures in Stem Cell Transplant Patients at Risk for Steroid Myopathy

NCT04521777
View directory record Official record
Conditions
Acute Graft Versus Host Disease
Interventions
Exercise Intervention, Physical Performance Testing, Questionnaire Administration
Behavioral · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Nov 6, 2026, 10:03 AM EST
Terminated Phase 3 Interventional

A Phase III Double-blind Study With Idebenone in Patients With Duchenne Muscular Dystrophy (DMD) Taking Glucocorticoid Steroids

NCT02814019
View directory record Official record
Conditions
Duchenne Muscular Dystrophy (DMD)
Interventions
Idebenone 150 mg film-coated tablets, placebo
Drug
Lead sponsor
Santhera Pharmaceuticals
Industry
Eligibility
10 Years and older · Male only
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
20
States / cities
Birmingham, Alabama • Phoenix, Arizona • Tucson, Arizona + 16 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2021 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 2Phase 3 Interventional Results available

Efficacy and Safety of Tideglusib in Congenital Myotonic Dystrophy

NCT03692312
View directory record Official record
Conditions
Congenital Myotonic Dystrophy
Interventions
Tideglusib, Placebo
Drug
Lead sponsor
AMO Pharma Limited
Industry
Eligibility
6 Years to 16 Years
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
9
States / cities
Little Rock, Arkansas • Los Angeles, California • Palo Alto, California + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Nov 6, 2026, 10:03 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics

NCT04226131
View directory record Official record
Conditions
Rheumatoid Arthritis, Healthy Controls
Interventions
Blood Draw, Disease Activity (DAS-28) Assessment, Skeletal Muscle Mitochondrial Respiratory Capacity, Muscle Biopsy, Body Composition, Cardiopulmonary Exercise Test (CPET), Strength Testing, Questionnaires, Skeletal Muscle Biomechanical Property Assessment
Other
Lead sponsor
Duke University
Other
Eligibility
25 Years to 75 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2023 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 2 Interventional Results available

Alisertib in Treating Patients With Advanced or Metastatic Sarcoma

NCT01653028
View directory record Official record
Conditions
Myxofibrosarcoma, Recurrent Adult Soft Tissue Sarcoma, Recurrent Leiomyosarcoma, Recurrent Liposarcoma, Recurrent Malignant Peripheral Nerve Sheath Tumor, Recurrent Undifferentiated Pleomorphic Sarcoma, Stage III Soft Tissue Sarcoma AJCC v7, Stage IV Soft Tissue Sarcoma AJCC v7
Interventions
Alisertib, Laboratory Biomarker Analysis
Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
235
States / cities
Scottsdale, Arizona • Aurora, Colorado • Boulder, Colorado + 153 more
Source: ClinicalTrials.gov public record
Updated Nov 30, 2017 · Synced Nov 6, 2026, 10:03 AM EST
Enrolling by invitation Phase 1 Interventional

A Phase 1b Study of Adenylosuccinic Acid (ASA-001) for Adenylosuccinate Synthase 1 (ADSS1) Deficient Myopathy.

NCT07412821
View directory record Official record
Conditions
Adenylosuccinate Synthase 1 Deficient Myopathy
Interventions
adenylosuccinic acid
Drug
Lead sponsor
Cure ADSSL1
Other
Eligibility
18 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Nov 6, 2026, 10:03 AM EST
Terminated Phase 3 Interventional

Efficacy Evaluation of Enobosarm Monotherapy in Treatment of AR+/ER+/HER2- Metastatic Breast Cancer

NCT04869943
View directory record Official record
Conditions
Metastatic Breast Cancer
Interventions
Enobosarm, Exemestane
Drug
Lead sponsor
Veru Inc.
Industry
Eligibility
18 Years to 100 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
34
States / cities
Chandler, Arizona • Gilbert, Arizona • Glendale, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jan 26, 2024 · Synced Nov 6, 2026, 10:03 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Electrical Impedance Myography and Ultrasound as Biomarkers of Duchenne Muscular Dystrophy

NCT01491555
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 30 Years · Male only
Enrollment
73 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 24, 2016 · Synced Nov 6, 2026, 10:03 AM EST
Completed Not applicable Interventional Accepts healthy volunteers

Brain Mechanisms of Juvenile Fibromyalgia

NCT03612258
View directory record Official record
Conditions
Fibromyalgia
Interventions
Functional Magnetic Resonance Imaging
Diagnostic Test
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
13 Years to 17 Years · Female only
Enrollment
153 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 6, 2025 · Synced Nov 6, 2026, 10:03 AM EST
Not listed No phase listed Observational Accepts healthy volunteers

Longitudinal Study of the Natural History of Duchenne Muscular Dystrophy (DMD)

NCT00468832
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
Not listed
Lead sponsor
Cooperative International Neuromuscular Research Group
Network
Eligibility
2 Years to 30 Years · Male only
Enrollment
551 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2019
U.S. locations
11
States / cities
Sacramento, California • Washington D.C., District of Columbia • Gainesville, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Apr 21, 2016 · Synced Nov 6, 2026, 10:03 AM EST
Terminated Phase 4 Interventional Results available

Platelet-rich Plasma vs. Whole Blood for Gluteus Medius Tendinopathy

NCT02978833
View directory record Official record
Conditions
Tendinopathy, Hip Pain
Interventions
PRP, Whole Blood, Ultrasound
Biological · Device
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
30 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Nov 6, 2026, 10:03 AM EST
Completed No phase listed Observational

A Study of Dosing Patterns and Costs in Patients With Spinal Muscular Atrophy Receiving Disease Modifying Therapies

NCT07378943
View directory record Official record
Conditions
Muscular Atrophy, Spinal
Interventions
Not listed
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
4,114 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 30, 2026 · Synced Nov 6, 2026, 10:03 AM EST
Completed No phase listed Observational Accepts healthy volunteers

Characterization of Skeletal Muscle Using Magnetic Resonance Elastography (MRE)

NCT00588432
View directory record Official record
Conditions
Stroke, Immobilization, Myofacial Pain, Hyperthyroid Myopathy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 4, 2009 · Synced Nov 6, 2026, 10:03 AM EST
Completed Phase 2 Interventional Accepts healthy volunteers

Muscle Treatment for Management of Pain & Disability in Tension-type Headache

NCT01244555
View directory record Official record
Conditions
Tension-type Headache
Interventions
ultrasound, massage
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 59 Years
Enrollment
69 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Dec 2, 2015 · Synced Nov 6, 2026, 10:03 AM EST
Terminated Phase 1 Interventional Accepts healthy volunteers

Molecular Regulation of Muscle Glucose Metabolism

NCT01581736
View directory record Official record
Conditions
Obesity, Type 2 Diabetes Mellitus
Interventions
U100 Humulin, Exercise
Drug · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
30 Years to 65 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Nov 27, 2017 · Synced Nov 6, 2026, 10:03 AM EST
Recruiting Phase 1Phase 2 Interventional

A Study of STM-416 Administered to Patients Undergoing TURBT for Recurrent Bladder Cancer

NCT05710848
View directory record Official record
Conditions
Non-muscle-invasive Bladder Cancer
Interventions
STM-416
Drug
Lead sponsor
SURGE Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
20
States / cities
Mesa, Arizona • Tucson, Arizona • Little Rock, Arkansas + 16 more
Source: ClinicalTrials.gov public record
Updated May 27, 2026 · Synced Nov 6, 2026, 10:03 AM EST
Completed Not applicable Interventional Accepts healthy volunteers Results available

Occupational Therapy's Role in Promoting Community Wellness Utilizing Sit-Stand Workstations

NCT03052426
View directory record Official record
Conditions
Musculoskeletal Pain, Musculoskeletal Strain, Sedentary Lifestyle
Interventions
Ergotron WorkFit - TL
Device
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 14, 2019 · Synced Nov 6, 2026, 10:03 AM EST