Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
Search Results

Search by objective public record fields.

Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results come from ClinicalTrials.gov. When the live registry is unavailable, a clearly labeled stored copy may be shown.

Clear filters

These results were retrieved from the live ClinicalTrials.gov registry. Filters and sort order apply to this result list.

ClinicalTrials.gov public records Last synced Oct 17, 2026, 6:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 121–144 of 182 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle Hypertonia Clear all
Completed Not applicable Interventional Accepts healthy volunteers

HIFEM for Arms, Lower Limbs, and Oblique Muscles

NCT04426526
View directory record Official record
Conditions
Muscle Tone Increased
Interventions
BTL 799-2
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
2
States / cities
Fort Collins, Colorado • New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2021 · Synced Oct 17, 2026, 6:02 AM EDT
Recruiting Phase 2 Interventional

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

NCT06782490
View directory record Official record
Conditions
Multiple Sclerosis Spasticity
Interventions
BMS-986368, Placebo
Drug
Lead sponsor
Celgene
Industry
Eligibility
18 Years to 70 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
16
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Aurora, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Oct 1, 2026 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 3 Interventional Results available

BOTOX® Treatment in Pediatric Upper Limb Spasticity

NCT01603602
View directory record Official record
Conditions
Pediatrics, Muscle Spasticity, Cerebral Palsy, Stroke
Interventions
botulinum toxin Type A, Normal Saline (Placebo)
Biological · Drug
Lead sponsor
Allergan
Industry
Eligibility
2 Years to 16 Years
Enrollment
235 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
20
States / cities
Pasadena, California • Pomona, California • Aurora, Colorado + 15 more
Source: ClinicalTrials.gov public record
Updated Aug 14, 2018 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Botox and Vibration on Bone in Children With Cerebral Palsy

NCT01803464
View directory record Official record
Conditions
Cerebral Palsy, Muscle Spasticity
Interventions
Low-magnitude vibration, Botox
Device · Drug
Lead sponsor
University of Delaware
Other
Eligibility
2 Years to 12 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
2
States / cities
Newark, Delaware • Wilmington, Delaware
Source: ClinicalTrials.gov public record
Updated Mar 20, 2018 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Not applicable Interventional

Exploring Advanced Imaging Techniques to Characterize Botulinum Toxin Diffusion in Human Muscle

NCT01412008
View directory record Official record
Conditions
Stroke, Muscle Spasticity
Interventions
Botox (botulinum toxin)
Drug
Lead sponsor
New York Presbyterian Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 1, 2013 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Not applicable Interventional

A Multifactorial Exercise Program to Reduce Falls in People With Parkinson Disease

NCT02302144
View directory record Official record
Conditions
Parkinson Disease
Interventions
Balance & Strengthening Exercises
Behavioral
Lead sponsor
Boston University Charles River Campus
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 1Phase 2 Interventional

ADX-629 Therapy for Sjogren-Larsson Syndrome

NCT05443685
View directory record Official record
Conditions
Sjogren-Larsson Syndrome
Interventions
ADX-629
Drug
Lead sponsor
University of Nebraska
Other
Eligibility
5 Years to 50 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Omaha, Nebraska
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Oct 17, 2026, 6:02 AM EDT
Recruiting No phase listed Observational

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

NCT05354622
View directory record Official record
Conditions
Hereditary Spastic Paraplegia, Neurodegenerative Diseases, Pediatric Disorder, Spasticity, Muscle, Motor Neuron Disease, Movement Disorders
Interventions
Not listed
Lead sponsor
Boston Children's Hospital
Other
Eligibility
1 Month to 30 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 18, 2026 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 4 Interventional

Safety of Xeomin for Lower Limb Spasticity in Multiple Sclerosis Patients

NCT01968902
View directory record Official record
Conditions
Muscle Spasticity, Multiple Sclerosis
Interventions
incabotulinumtoxinA, Placebo
Biological
Lead sponsor
Multiple Sclerosis Center of Northeastern New York
Other
Eligibility
18 Years to 65 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Latham, New York
Source: ClinicalTrials.gov public record
Updated Mar 22, 2017 · Synced Oct 17, 2026, 6:02 AM EDT
Completed No phase listed Observational

Prevalence of Spasticity in Adults With Mental Retardation Living in the Community

NCT00282191
View directory record Official record
Conditions
Mental Retardation, Spasticity
Interventions
Not listed
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
1
States / cities
Davidson County, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 28, 2008 · Synced Oct 17, 2026, 6:02 AM EDT
Completed No phase listed Observational

A Study to Collect Participants Experience of Living With Adult Upper Limb (AUL) Spasticity and to Assess the Arm Activity Measure (ArmA)

NCT05546190
View directory record Official record
Conditions
Spastic Hemiparesis, Muscle Spasticity
Interventions
Not listed
Lead sponsor
Ipsen
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
2
States / cities
Downey, California • Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 17, 2026, 6:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis

NCT00023075
View directory record Official record
Conditions
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 17, 2026, 6:02 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Cannabis for Spasticity in Multiple Sclerosis

NCT00682929
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
Inhaled Cannabis, Oral THC, Oral Placebo, Inhaled placebo
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
21 Years and older
Enrollment
41 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 3 Interventional Results available

Dysport® Pediatric Lower Limb Spasticity Follow-on Study

NCT01251380
View directory record Official record
Conditions
Cerebral Palsy, Muscle Spasticity, Children
Interventions
Botulinum toxin type A
Biological
Lead sponsor
Ipsen
Industry
Eligibility
2 Years to 17 Years
Enrollment
216 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
8
States / cities
Aurora, Colorado • Chicago, Illinois • New Orleans, Louisiana + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 28, 2022 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Not applicable Interventional

Changes in Pain, Spasticity, and Quality of Life After Use of Counterstrain Treatment in Individuals With SCI

NCT05559255
View directory record Official record
Conditions
Pain, Spasticity, Muscle, Quality of Life
Interventions
Counterstrain manual manipulative treatment
Other
Lead sponsor
William Carey University
Other
Eligibility
21 Years to 70 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Hattiesburg, Mississippi
Source: ClinicalTrials.gov public record
Updated Aug 6, 2024 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 3 Interventional

One Year, Open Label, Dose Escalation Long-term Safety Study in Multiple Sclerosis (MS) Subjects With Spasticity

NCT01844232
View directory record Official record
Conditions
Multiple Sclerosis, Spasticity
Interventions
arbaclofen
Drug
Lead sponsor
RVL Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
21
States / cities
Gilbert, Arizona • Phoenix, Arizona • Pasadena, California + 17 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2022 · Synced Oct 17, 2026, 6:02 AM EDT
Terminated Not applicable Interventional

Bilateral Versus Unilateral Task Retraining Using the SaeboFlex Orthosis

NCT00893776
View directory record Official record
Conditions
Muscle Spasticity
Interventions
Task Training
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2014
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 26, 2017 · Synced Oct 17, 2026, 6:02 AM EDT
Completed No phase listed Observational

Measures of Motor Impairment in Early Parkinson's Disease

NCT00291265
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
30 Years to 85 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 17, 2026, 6:02 AM EDT
Completed No phase listed Observational

Classification of Cerebral Palsy Subtypes

NCT00072800
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 2 Interventional

Botulinum Toxin (BOTOX) for Cerebral Palsy

NCT00060957
View directory record Official record
Conditions
Cerebral Palsy, Muscle Spasticity
Interventions
Botulinum toxin type A
Drug
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
3 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1997
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 26, 2016 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 3 Interventional

Safety Study of 3 mg/mL Baclofen Injection (Intrathecal) Using A Programmable Pump

NCT01520545
View directory record Official record
Conditions
Severe Spasticity
Interventions
Gablofen® 3 mg/mL (baclofen injection), SynchroMed® II Programmable Pump
Drug · Device
Lead sponsor
Piramal Critical Care, Ltd.
Industry
Eligibility
4 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
13
States / cities
Little Rock, Arkansas • Loma Linda, California • Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated May 3, 2019 · Synced Oct 17, 2026, 6:02 AM EDT
Recruiting Not applicable Interventional

The Effect of Cupping on Spasticity and Function of the Lower Extremity During Rehabilitation After Stroke

NCT06653855
View directory record Official record
Conditions
Stroke Gait Rehabilitation
Interventions
Dry Static Cupping, Placebo cupping, Standard physical therapy treatment
Other
Lead sponsor
Scott Getsoian
Industry
Eligibility
30 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Joliet, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 13, 2024 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Not applicable Interventional Results available

Passive Tactile Stimulation for Stroke Rehabilitation

NCT03814889
View directory record Official record
Conditions
Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
Interventions
Vibration pattern, No vibration
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Apr 8, 2024 · Synced Oct 17, 2026, 6:02 AM EDT
Completed Phase 2 Interventional

A Study With IPX056 in Subjects With Spasticity Associated With Multiple Sclerosis

NCT00914290
View directory record Official record
Conditions
Spasticity, Multiple Sclerosis
Interventions
IPX056, Baclofen IR, Placebo IPX056, Placebo IR
Drug
Lead sponsor
Impax Laboratories, LLC
Industry
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
11
States / cities
Tucson, Arizona • Aurora, Colorado • Tampa, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Nov 6, 2019 · Synced Oct 17, 2026, 6:02 AM EDT