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Showing 1–24 of 45 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Muscle Protein Synthesis Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Casein Protein and Leucine Supplementation in Chronic Obstructive Pulmonary Disease (COPD)

NCT01734473
View directory record Official record
Conditions
COPD
Interventions
Hydrolyzed casein protein, Hydrolyzed casein protein + carbohydrates, Hydrolyzed casein protein + leucine, Hydrolyzed casein protein + carbohydrates + leucine, 4 levels of hydrolyzed casein protein + carbohydrates
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving the Anabolic Action of Plant-based Foods Using Complementary Proteins

NCT06781723
View directory record Official record
Conditions
Health, Recreational Activities, Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis
Interventions
Resistance Exercise, Isolated Mixture, Rice and Beans
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Protein Blends (Soy, Whey and Casein) for Muscle Synthesis

NCT01358305
View directory record Official record
Conditions
Muscle Synthesis
Interventions
Protein Blend
Other
Lead sponsor
DuPont Nutrition and Health
Industry
Eligibility
18 Years to 35 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Oct 6, 2019 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional

Effects of Nutritional Supplementation (Product 4808) on Acute Skeletal Muscle Protein Synthesis in Cancer Patients

NCT00446888
View directory record Official record
Conditions
Cancer
Interventions
Standardized Meals for Diet Stabilization, Forticare, Product 4808
Behavioral · Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
40 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Jun 18, 2009 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Essential Amino Acids and Protein Kinetics During Caloric Deprivation

NCT03372928
View directory record Official record
Conditions
Muscle Protein Synthesis, Whole-body Protein Balance
Interventions
Standard EAA, High EAA
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 19, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistance Exercise and Muscle Protein Synthesis in Obese Adults

NCT03411681
View directory record Official record
Conditions
Obesity
Interventions
Resistance Exercise
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 45 Years
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers

Essential Amino Acids Supplementation and Muscle Protein Synthesis

NCT01366924
View directory record Official record
Conditions
Muscle Loss, Muscle Anabolism
Interventions
Essential Amino Acids, Endurance exercise
Dietary Supplement · Other
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2010
U.S. locations
2
States / cities
Boston, Massachusetts • Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 20, 2017 · Synced Jun 10, 2026, 3:44 AM EDT
Completed No phase listed Observational

Genomic Translation for Amyotrophic Lateral Sclerosis Care

NCT02795897
View directory record Official record
Conditions
ALS
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 80 Years
Enrollment
254 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2022
U.S. locations
13
States / cities
Los Angeles, California • Aurora, Colorado • Ann Arbor, Michigan + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Skeletal Muscle Protein Synthesis: Traditional and Cluster Sets

NCT04028726
View directory record Official record
Conditions
Resistance Exercise
Interventions
Back-squat exercise
Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 23, 2019 · Synced Jun 10, 2026, 3:44 AM EDT
Terminated Phase 1Phase 2 Interventional

Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy

NCT01847573
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
HT-100
Drug
Lead sponsor
Processa Pharmaceuticals
Industry
Eligibility
6 Years to 20 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Sacramento, California • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Whey Protein Hydrolysate on Human Muscle Protein Synthesis

NCT03313830
View directory record Official record
Conditions
Healthy
Interventions
Whey Protein Hydrolysate (WPH), Intact Whey Protein (WHEY)
Dietary Supplement
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
20 Years to 35 Years · Male only
Enrollment
11 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 9, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults

NCT03870165
View directory record Official record
Conditions
Hypertrophy
Interventions
Resistance exercise, Salmon, Isolated amino acids and fatty acids
Behavioral · Other · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 35 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 27, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

"Effect of High Fat and High Glycemic Diets

NCT01494935
View directory record Official record
Conditions
Type 2 Diabetes
Interventions
High Glycemic Diet, Control diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
40 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2019
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Diet Synergy in Muscle Protein Synthesis

NCT07367854
View directory record Official record
Conditions
Muscle Protein Synthetic Response to Protein, Muscle Protein Synthesis, Muscle Health, Protein Metabolism, Recreational Activities, Isotope Labeling
Interventions
Resistance Exercise, Potato and Beef, Bread and Beef, Beef
Behavioral · Dietary Supplement
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
19 Years to 40 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Jun 10, 2026, 3:44 AM EDT
Terminated Phase 2 Interventional

Open Label Extension Study of HT-100 in Patients With DMD

NCT01978366
View directory record Official record
Conditions
Duchenne Muscular Dystrophy
Interventions
HT-100
Drug
Lead sponsor
Processa Pharmaceuticals
Industry
Eligibility
6 Years to 20 Years · Male only
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
5
States / cities
Sacramento, California • Baltimore, Maryland • St Louis, Missouri + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Amino Acid Profile and Muscle Protein Synthetic Response to Consuming Meat or Plant-based Alternatives

NCT04784806
View directory record Official record
Conditions
Healthy
Interventions
Ground beef, Ground pork, Tofu, Beyond Meat
Other
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 30 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jan 13, 2022 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Defining Beef and Meal Frequency as Key Components of a Healthy Eating Pattern for Muscle Health and Wellbeing

NCT04232254
View directory record Official record
Conditions
Meal Frequency, Dietary Habits, Muscle Protein Synthesis
Interventions
Animal-based Protein Foods, Skewed Protein Distribution, Plant-based Protein Foods, Balanced Protein Distribution
Behavioral
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 16, 2025 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Peanut Protein Supplementation to Augment Muscle Growth and Improve Markers of Muscle Quality and Health in Older Adults

NCT04015479
View directory record Official record
Conditions
Aging, Sarcopenia
Interventions
Peanut Protein Powder, Full body resistance training
Dietary Supplement · Behavioral
Lead sponsor
Auburn University
Other
Eligibility
50 Years to 80 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Auburn, Alabama
Source: ClinicalTrials.gov public record
Updated Jan 11, 2021 · Synced Jun 10, 2026, 3:44 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Anti-Inflammatory Milk Matrix

NCT04216004
View directory record Official record
Conditions
Obesity, Skeletal Muscle, Inflammation
Interventions
Controlled-Feeding Intervention, Non-dairy beverage, Full-fat milk, Fat-free milk
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
40 Years to 59 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2024
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated May 8, 2023 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Eicosapentaenoic Acid and Protein Modulation to Induce Anabolism in Chronic Obstructive Pulmonary Disease (COPD): Aim 2

NCT01624792
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease, Muscle Wasting
Interventions
Olive oil, Fish oil, Fish oil and placebo
Dietary Supplement
Lead sponsor
Texas A&M University
Other
Eligibility
45 Years and older
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2016
U.S. locations
1
States / cities
College Station, Texas
Source: ClinicalTrials.gov public record
Updated Sep 29, 2025 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Essential Amino Acid-enriched Whey and Carbohydrate Co-ingestion on Protein Kinetics

NCT04621175
View directory record Official record
Conditions
Energy Deficit
Interventions
EAA+W & Carbohydrate, EAA+W & EAA
Dietary Supplement
Lead sponsor
United States Army Research Institute of Environmental Medicine
Federal
Eligibility
18 Years to 35 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Natick, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 26, 2025 · Synced Jun 10, 2026, 3:44 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nutritional Strategies to Augment the Postprandial Muscle Protein Synthetic Response to the Ingestion of a Low Dose of Protein in Middle-aged Women

NCT02918981
View directory record Official record
Conditions
Aging
Interventions
Resistance Exercise, 14 g Whey protein, 6.6 g Whey protein + 1.25 g leucine, 4 g Whey protein + 1.25 g leucine + 2.6 g Whey peptides, 6.6 g Whey protein + 1.25 g leucine + 0.8 g Citrulline, Water control
Behavioral · Dietary Supplement · Other
Lead sponsor
University of Illinois at Urbana-Champaign
Other
Eligibility
20 Years to 79 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Urbana, Illinois
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Jun 10, 2026, 3:44 AM EDT
Not listed Not applicable Interventional

Nutritional Stimulation of Muscle Protein Synthesis and Metabolic Rate After Bariatric Surgery

NCT04751916
View directory record Official record
Conditions
Weight Loss
Interventions
Essential Amino Acid Protein Supplement, Beneprotein®
Dietary Supplement
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 3, 2023 · Synced Jun 10, 2026, 3:44 AM EDT
Terminated Not applicable Interventional

Moderate Intensity Exercise and Phenylketonuria

NCT01904708
View directory record Official record
Conditions
Phenylketonuria, PKU
Interventions
Acute Moderate Intensity Exercise
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
14 Years to 17 Years · Male only
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Oct 15, 2014 · Synced Jun 10, 2026, 3:44 AM EDT