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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Muscle Tone Clear all
Completed Not applicable Interventional Accepts healthy volunteers

MRI Evaluation of Change in Gluteal Muscles Following the Treatment With HIFEM Device

NCT03815747
View directory record Official record
Conditions
Muscle Tone Increased
Interventions
High-Intensity Focused Electromagnetic (HIFEM) Field Device
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years and older
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Solana Beach, California
Source: ClinicalTrials.gov public record
Updated May 19, 2020 · Synced Jun 10, 2026, 9:16 PM EDT
Completed No phase listed Observational

Classification of Cerebral Palsy Subtypes

NCT00072800
View directory record Official record
Conditions
Cerebral Palsy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
115 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 10, 2026, 9:16 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Electrical Muscle Stimulation with 1064 Nm Diode Laser and RF/PEMF for Non-invasive Body Contouring and Fat Reduction.

NCT05256771
View directory record Official record
Conditions
Fat Reduction, Muscle Tone Increased
Interventions
EMS, 1064 nm diode laser, RF/PEMF
Device
Lead sponsor
Venus Concept
Industry
Eligibility
18 Years to 65 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
3
States / cities
San Diego, California • Hackensack, New Jersey • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 27, 2025 · Synced Jun 10, 2026, 9:16 PM EDT
Recruiting Not applicable Interventional

Voice Therapy Per the Rehabilitation Treatment Specification System

NCT06152627
View directory record Official record
Conditions
Muscle Tension Dysphonia
Interventions
Standard of care voice therapy with novice clinician RTSS-Voice documentation, Standard of care voice therapy with expert clinician RTSS-Voice documentation
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
14 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
5
States / cities
Atlanta, Georgia • Boston, Massachusetts • New York, New York + 2 more
Source: ClinicalTrials.gov public record
Updated May 25, 2026 · Synced Jun 10, 2026, 9:16 PM EDT
Recruiting Not applicable Interventional

Deconstructing Voice Therapy: Towards Enhanced Communication Outcomes

NCT07176988
View directory record Official record
Conditions
Dysphonia, Primary Muscle Tension Dysphonia (MTD)
Interventions
Hierarchical method, Non Hierarchical method
Other
Lead sponsor
Emory University
Other
Eligibility
16 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Enhanced External Counterpulsation on Delayed Onset Muscle Soreness

NCT02175316
View directory record Official record
Conditions
Muscle Tightness
Interventions
Enhanced External Counterpulsation
Device
Lead sponsor
David Grant U.S. Air Force Medical Center
Federal
Eligibility
25 Years to 59 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Travis Air Force Base, California
Source: ClinicalTrials.gov public record
Updated Apr 21, 2020 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Lipolysis and Improvement of Muscle Tone in Lateral Abdomen

NCT05540080
View directory record Official record
Conditions
Fat Burn
Interventions
BTL-899
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
46 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
6
States / cities
Sacramento, California • Greenwood Village, Colorado • Marietta, Georgia + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional

EMG Guided Botulinum Toxin Type A Injections for Refractory High Tone Pelvic Floor Dysfunction

NCT01323829
View directory record Official record
Conditions
High Tone Pelvic Floor Dysfunction
Interventions
EMG Guidance of Injection
Other
Lead sponsor
Pelvic and Sexual Health Institute
Other
Eligibility
18 Years to 79 Years · Female only
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2014 · Synced Jun 10, 2026, 9:16 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Non-invasive Buttock Lifting Induced by Magnetic Device - Multicentric Study

NCT03579147
View directory record Official record
Conditions
Muscle Tightness
Interventions
Treatment with BTL EMSCULPT device
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
6
States / cities
Gilbert, Arizona • Beverly Hills, California • Miami, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated May 25, 2020 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Role of Therapy for Muscle Tension Dysphagia

NCT02647931
View directory record Official record
Conditions
Muscle Tension Dysphagia
Interventions
Voice therapy for Muscle Tension Dysphagia
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Scottsdale, Arizona
Source: ClinicalTrials.gov public record
Updated Mar 13, 2018 · Synced Jun 10, 2026, 9:16 PM EDT
Completed No phase listed Observational

Sensory Function in Idiopathic Voice Disorders

NCT00001922
View directory record Official record
Conditions
Phonation Disorder, Spastic Dysphonia, Voice Disorder
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
20 Years to 80 Years
Enrollment
370 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1998
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Non-invasive Lipolysis and Improvement of Muscle Tone in Upper Arms

NCT04596241
View directory record Official record
Conditions
Fat Disorder
Interventions
BTL-899
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
2
States / cities
Chicago, Illinois • Hunt Valley, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 28, 2022 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging

NCT02685319
View directory record Official record
Conditions
Flaccid Muscle Tone
Interventions
muscle biopsy
Procedure
Lead sponsor
Purdue University
Other
Eligibility
20 Years to 29 Years · Male only
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
West Lafayette, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Results available

Preliminary Study 2 to Test the Effects of Ambulatory Voice Biofeedback

NCT03416868
View directory record Official record
Conditions
Vocal Fold Nodules, Muscle Tension Dysphonia
Interventions
Ambulatory voice biofeedback
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Jun 10, 2026, 9:16 PM EDT
Terminated Phase 3 Interventional Results available

Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis

NCT04984278
View directory record Official record
Conditions
Spasticity With Multiple Sclerosis
Interventions
Nabiximols, Placebo
Drug
Lead sponsor
Jazz Pharmaceuticals
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
6
States / cities
Denver, Colorado • Naples, Florida • Tampa, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 10, 2024 · Synced Jun 10, 2026, 9:16 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Non-invasive Improvement of Buttocks With Magnetic Device

NCT03575507
View directory record Official record
Conditions
Muscle Tightness
Interventions
Treatment with BTL EMSCULPT device.
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older · Female only
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Roller Massage on Short-Term Passive Muscle Stiffness

NCT04571034
View directory record Official record
Conditions
Muscle Tightness
Interventions
Sham Therapeutic Ultrasound, Medium-Intensity Roller Massage, High-Intensity Roller Massage
Procedure
Lead sponsor
Jeffrey Sykora
Other
Eligibility
18 Years to 30 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 8, 2022 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of OA Decompression on the Autonomic Nervous System

NCT00403936
View directory record Official record
Conditions
Muscle Tension
Interventions
OA decompression manipulation
Procedure
Lead sponsor
Nova Southeastern University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Feb 24, 2010 · Synced Jun 10, 2026, 9:16 PM EDT
Recruiting No phase listed Observational

Imaging Genetics of Laryngeal Dystonia

NCT03042975
View directory record Official record
Conditions
Laryngeal Dystonia, Unaffected Relatives of Laryngeal Dystonia Patients, Voice Tremor, Muscle Tension Dysphonia
Interventions
MRI, Blood draw
Other · Procedure
Lead sponsor
Kristina Simonyan
Other
Eligibility
Not listed
Enrollment
410 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jun 10, 2026, 9:16 PM EDT
Completed No phase listed Observational

Efficacy of Conversation Training Therapy (CTT)

NCT02441348
View directory record Official record
Conditions
Voice Disorders
Interventions
Conversation Training Therapy
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 7, 2019 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

A Study to Evaluate Effects of Gargle Phonation in Voice

NCT04766658
View directory record Official record
Conditions
Voice Disorders, Muscle Tension Dysphonia, Speech Therapy
Interventions
Gargle Phonation, Water swallow
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 89 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
2
States / cities
Scottsdale, Arizona • Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Oct 18, 2022 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cranial Laser Reflex Technique for Hamstring Function

NCT03044106
View directory record Official record
Conditions
Hamstring Injury, Muscle Tone Increased, Muscle Pain, Muscle Weakness
Interventions
CLRT
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 35 Years
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 11, 2019 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Phase 2 Interventional

Prospective Studies of the Use of Self Hypnosis, Acupuncture and Osteopathic Manipulation on Muscle Tension in Children With Spastic Cerebral Palsy

NCT00011024
View directory record Official record
Conditions
Spastic Cerebral Palsy
Interventions
Self Hypnosis, Acupuncture, Osteopathic Manipulation
Procedure
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
4 Years to 21 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1998 – 2004
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 17, 2006 · Synced Jun 10, 2026, 9:16 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Abdomen - Fat Reduction and Muscle Toning

NCT04587804
View directory record Official record
Conditions
Fat Burn
Interventions
rPMS+RF
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
21 Years and older
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
2
States / cities
Macon, Georgia • Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 31, 2021 · Synced Jun 10, 2026, 9:16 PM EDT