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ClinicalTrials.gov public records Last synced Oct 7, 2026, 6:14 AM EDT

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Showing 97–120 of 127 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Muscle and Joint Pain Clear all
Completed Phase 3 Interventional Results available

S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy

NCT01598298
View directory record Official record
Conditions
Breast Cancer, Musculoskeletal Complications, Pain
Interventions
duloxetine hydrochloride, placebo
Drug · Other
Lead sponsor
SWOG Cancer Research Network
Network
Eligibility
Up to 120 Years · Female only
Enrollment
299 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
714
States / cities
Anchorage, Alaska • Fairbanks, Alaska • Jonesboro, Arkansas + 475 more
Source: ClinicalTrials.gov public record
Updated Dec 16, 2022 · Synced Oct 7, 2026, 6:14 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

JIT: Effect of Pain on DT in TMD

NCT06659991
View directory record Official record
Conditions
Temporomandibular Disorder (TMD)
Interventions
alcohol condition, control condition
Drug · Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years to 65 Years
Enrollment
160 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 2Phase 3 Interventional

Diclofenac Patch for Treatment of Mild to Moderate Tendonitis or Bursitis

NCT00640939
View directory record Official record
Conditions
Rotator Cuff Tendonitis, Bicipital Tendonitis, Subdeltoid Bursitis of the Shoulder, Subacromial Bursitis of the Shoulder, Medial Epicondylitis of the Elbow, Lateral Epicondylitis of the Elbow, DeQuervain's Tenosynovitis of the Wrist
Interventions
diclofenac sodium, Matching Placebo
Drug
Lead sponsor
Cerimon Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Aug 6, 2008 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 2 Interventional Results available

Comparison of Psychological and Pharmacological Treatments for Pain Due to Temporomandibular Joint Disorder (TMD)

NCT00066937
View directory record Official record
Conditions
Temporomandibular Joint Disorders
Interventions
Nortriptyline Oral Capsule, Benztropine Oral Product, CBT, Disease MGT
Drug · Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
140 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2008
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 24, 2017 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional Results available

Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated

NCT03100539
View directory record Official record
Conditions
Neck Pain, Chronic Pain, Pain, Arthritis, Musculoskeletal Pain, Osteoarthritis
Interventions
Therapist treated massage, Care ally assisted massage
Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
395 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 20, 2024 · Synced Oct 7, 2026, 6:14 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Embo Registry; National Registry for Artery Embolization

NCT06477965
View directory record Official record
Conditions
Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder, Pain, Chronic, Tendonitis Elbow, Tendonitis Shoulder, Tendonitis;Achilles, Tenosynovitis
Interventions
Artery Embolization
Procedure
Lead sponsor
Vascular Solutions of North Carolina
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2029
U.S. locations
2
States / cities
Cary, North Carolina • Winchester, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 28, 2024 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Pilot Study of the Efficacy & Safety of Natural Eggshell Membrane (NEM) for Joint & Connective Tissue Disorders

NCT00750230
View directory record Official record
Conditions
Osteoarthritis, Fibromyalgia
Interventions
NEM
Dietary Supplement
Lead sponsor
ESM Technologies, LLC
Industry
Eligibility
18 Years to 100 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2004
U.S. locations
1
States / cities
Carthage, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 7, 2023 · Synced Oct 7, 2026, 6:14 AM EDT
Terminated No phase listed Observational

Role of Biomarkers in Muscle Pain and Joint Pain in Patients With Solid Tumors Receiving Paclitaxel

NCT01096407
View directory record Official record
Conditions
Arthralgia, Pain, Unspecified Adult Solid Tumor, Protocol Specific
Interventions
laboratory biomarker analysis, questionnaire administration, assessment of therapy complications
Other · Procedure
Lead sponsor
Vanderbilt-Ingram Cancer Center
Other
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Apr 4, 2013 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 4 Interventional Results available

A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction

NCT01524913
View directory record Official record
Conditions
Temporomandibular Joint Dysfunction, Pain, Arthrocentesis
Interventions
Hyaluronic acid, Corticosteroid, Lactated Ringers
Drug
Lead sponsor
Emory University
Other
Eligibility
18 Years to 90 Years
Enrollment
102 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
5
States / cities
Los Angeles, California • Atlanta, Georgia • Cinncinati, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Manipulation Effects on Abdominal Muscles

NCT01745939
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbar Manipulation, Sham manipulation
Other
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Nov 5, 2014 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional Results available

Effectiveness of the Compression Belt for Patients With Sacroiliac Joint Pain

NCT01559948
View directory record Official record
Conditions
Low Back Pain
Interventions
Lumbopelvic stabilization exercise, Sacroiliac joint belt
Behavioral · Device
Lead sponsor
Texas Woman's University
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 7, 2019 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

High-speed Power Training in Older Adults With Knee Osteoarthritis (OA)

NCT01328340
View directory record Official record
Conditions
Knee Osteoarthritis
Interventions
High-speed power training, Slow-speed strength training
Other
Lead sponsor
University of Missouri-Columbia
Other
Eligibility
55 Years and older
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Columbia, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 4, 2016 · Synced Oct 7, 2026, 6:14 AM EDT
Recruiting Not applicable Interventional

Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)

NCT06214923
View directory record Official record
Conditions
Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Interventions
RelieVRx, Sham-VR, No-VR (natural history control)
Device · Other
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years to 88 Years
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 7, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Recruiting Not applicable Interventional

A Pilot Study to Evaluate the Effectiveness of Focused Massage on Pain, Mobility, and Quality of Life During Radiation Treatment for Patients With Breast Cancer

NCT07447700
View directory record Official record
Conditions
Breast Cancer, Radiation Therapy Patient
Interventions
upper body massage
Other
Lead sponsor
Ohio State University Comprehensive Cancer Center
Other
Eligibility
18 Years and older
Enrollment
55 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 2, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Protocol For The Quantitation Of Pain In The Diagnosis Of Polymyalgia Rheumatica

NCT00847236
View directory record Official record
Conditions
Polymyalgia Rheumatica, Rheumatoid Arthritis, Rheumatic Disease
Interventions
Not listed
Lead sponsor
Lahey Clinic
Other
Eligibility
50 Years and older
Enrollment
142 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2013
U.S. locations
1
States / cities
Arlington, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 23, 2017 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 3 Interventional

Study to Evaluate the Efficacy and Safety of OraVescent Fentanyl Citrate Treatment for the Management of Breakthrough Pain in Opioid-Tolerant Patients With Noncancer-Related Chronic Pain

NCT00343733
View directory record Official record
Conditions
Pain
Interventions
OraVescent Fentanyl
Drug
Lead sponsor
Cephalon
Industry
Eligibility
18 Years to 80 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
21
States / cities
Hot Springs, Arkansas • Los Gatos, California • Oxnard, California + 16 more
Source: ClinicalTrials.gov public record
Updated May 9, 2014 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 2 Interventional Results available

Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments

NCT03844412
View directory record Official record
Conditions
Vestibulodynia, Temporomandibular Disorder, Fibromyalgia Syndrome, Irritable Bowel Syndrome, Migraines, Tension Headache, Endometriosis, Interstitial Cystitis, Back Pain, Chronic Fatigue Syndrome
Interventions
5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline, Placebo cream, Placebo pill
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Los Angeles, California • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 19, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Not yet recruiting Not applicable Interventional

Marine Lipids Ease Painful TMD

NCT07437313
View directory record Official record
Conditions
Temporomandibular Disorder (TMD)
Interventions
SPM Precursor-Enriched Marine Lipid Supplement, Medium-Chain Triglyceride Supplement
Dietary Supplement
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

NCT02971072
View directory record Official record
Conditions
Acute Pain, Atrophic, Goals, Impairment, Infiltration, Injury, Muscle Weakness, Pain, Pathology, Shoulder Pain, Syndrome, Tendinopathy
Interventions
Subacromial injection, Physical Therapy
Procedure · Other
Lead sponsor
University of Oregon
Other
Eligibility
21 Years to 45 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 7, 2026, 6:14 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Connectivity Patterns in Chronic Temporomandibular Joint Disorders

NCT05068908
View directory record Official record
Conditions
Chronic Pain, Temporomandibular Joint Disorders, Temporomandibular Joint Pain
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
75 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Clinical Research Study to Evaluate Selegiline in the Treatment of Borderline Personality Disorder

NCT01912391
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Selegiline, Placebo (for Selegiline)
Drug
Lead sponsor
Mood and Anxiety Research, Inc
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Fresno, California
Source: ClinicalTrials.gov public record
Updated Oct 8, 2015 · Synced Oct 7, 2026, 6:14 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

PatientSpot Formerly Known as ArthritisPower

NCT03840928
View directory record Official record
Conditions
Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout, Crohn Disease, Juvenile Idiopathic Arthritis, Lupus Erythematosus, Myositis, Osteoarthritis, Osteoporosis, Psoriasis, Psoriatic Arthritis, Scleroderma, Dermatomyositis, Inflammatory Bowel Diseases, Polymyositis, Axial Spondyloarthritis, Diffuse Idiopathic Skeletal Hyperostosis, Polymyalgia Rheumatica, Giant Cell Arteritis, Temporal Arteritis, Wegener, Relapsing Polychondritis, Undifferentiated Connective Tissue Disease, Spinal Cord Injuries, Alzheimer Disease, Amyotrophic Lateral Sclerosis, Ataxia, Bell Palsy, Brain Tumor, Cerebral Aneurysm, Epilepsy, Guillain-Barre Syndrome, Headache, Head Injury, Hydrocephalus, Lumbar Disc Disease, Meningitis, Multiple Sclerosis, Muscular Dystrophy, Neurocutaneous Syndromes, Parkinson Disease, Stroke, Cluster Headache, Tension-Type Headache, Chronic Obstructive Pulmonary Disease, Asthma, Lung Cancer, Cystic Fibrosis, Sleep Apnea, Eczema, Alopecia, Chronic Inflammation, Unstable Angina, Heart Attack, Heart Failure, Arrythmia, Valve Heart Disease, High Blood Pressure, Congenital Heart Disease, Peripheral Arterial Disease, Diabetes, Chronic Liver Disease, Obesity
Interventions
Not listed
Lead sponsor
Global Healthy Living Foundation
Other
Eligibility
19 Years and older
Enrollment
40,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2025
U.S. locations
1
States / cities
Upper Nyack, New York
Source: ClinicalTrials.gov public record
Updated Dec 13, 2023 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional

A Controlled Study to Evaluate the Effects of a Topical Cream on Symptoms of Arthritis, Joint, and Muscle Pain

NCT07767669
View directory record Official record
Conditions
Arthritis, Joint Pain, Muscle Pain, Musculoskeletal Pain, Joint Stiffness
Interventions
Intervention (Saje Pain Release Joint & Arthritis Cream), Placebo Comparator
Dietary Supplement
Lead sponsor
Saie Beauty
Industry
Eligibility
20 Years to 65 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 7, 2026, 6:14 AM EDT
Completed Not applicable Interventional

Tonation Breathing Technique Method to Ease Aromatase Inhibitor-induced Joint and/or Muscle Pain

NCT05412953
View directory record Official record
Conditions
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
Interventions
Questionnaire Administration, Tonation Breathing Technique
Other · Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 3, 2024 · Synced Oct 7, 2026, 6:14 AM EDT